High Polygenic Risk Is Associated with Earlier Initiation and Escalation of Treatment in Early Primary Open-Angle Glaucoma

Authors: Marshall, Henry N., Mullany, Sean, Han, Xikun, Qassim, Ayub, He, Weixiong, Hassall, Mark M., Schmidt, Joshua, Thomson, Daniel, Nguyen, Thi Thi, Berry, Ella C., Knight, Lachlan S.W., Hollitt, Georgina L., Ridge, Bronwyn, Schulz, Angela, Mills, Richard A., Healey, Paul R., Agar, Ashish, Galanopoulos, Anna, Landers, John, Graham, Stuart L., Hewitt, Alex W., Casson, Robert J., MacGregor, Stuart, Siggs, Owen M., Craig, Jamie E.

Source: Ophthalmology. 130(8):830-836

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Association Between Body Mass Index and Primary Open Angle Glaucoma in Three Cohorts

Authors: Marshall, Henry, Berry, Ella C, Torres, Santiago Diaz, Mullany, Sean, Schmidt, Joshua, Thomson, Daniel, Nguyen, Thi Thi, Knight, Lachlan SW, Hollitt, Georgina, Qassim, Ayub, Kolovos, Antonia, Ridge, Bronwyn, Schulz, Angela, Lake, Stewart, Mills, Richard A, Agar, Ashish, Galanopoulos, Anna, Landers, John, Healey, Paul R, Graham, Stuart L, Hewitt, Alex W, Casson, Robert J, MacGregor, Stuart, Siggs, Owen M, Craig, Jamie E

Source: American journal of ophthalmology. 245:126-133

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No Strong Association between the Apolipoprotein E E4 Allele and Glaucoma: A Multicohort Study

Authors: Mullany, Sean, Diaz-Torres, Santiago, Schmidt, Joshua M., Thomson, Daniel, Qassim, Ayub, Marshall, Henry N., Knight, Lachlan S.W., Berry, Ella C., Kolovos, Antonia, Dimasi, David, Lake, Stewart, Mills, Richard A., Landers, John, Mitchell, Paul, Healey, Paul R., Commerford, Toby, Klebe, Sonja, Souzeau, Emmanuelle, Hassall, Mark M., MacGregor, Stuart, Gharahkhani, Puya, Siggs, Owen M., Craig, Jamie E.

Source: In Ophthalmology Science September 2023 3(3)

Comparative study of 2‐year outcomes for Hydrus or iStent inject microinvasive glaucoma surgery implants with cataract surgery

Authors: Holmes, David P., Clement, Colin I., Nguyen, Vuong, Healey, Paul R., Lim, Ridia, White, Andrew, Yuen, Joshua, Lawlor, Mitchell

Source: Clinical & experimental ophthalmology. 50(3):303-311

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Classification of Visual Field Abnormalities in Highly Myopic Eyes without Pathologic Change

Authors: Lin, Fengbin, Chen, Shida, Song, Yunhe, Li, Fei, Wang, Wei, Zhao, Zhenni, Gao, Xinbo, Wang, Peiyuan, Jin, Ling, Liu, Yuhong, Chen, Meiling, Liang, Xiaohong, Yang, Bin, Ning, Guili, Cheng, Ching-Yu, Healey, Paul R., Park, Ki Ho, Zangwill, Linda M., Aung, Tin, Ohno-Matsui, Kyoko, Jonas, Jost B., Weinreb, Robert N., Zhang, Xiulan

Source: Ophthalmology. 129(7):803-812

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Classification of Visual Field Abnormalities in Highly Myopic Eyes without Pathologic Change

Authors: Liu, Yizhi, Lv, Lin, Friedman, David, Gao, Kai, Liu, Bingqian, Bressler, Neil M., He, Mingguang, Chen, Xiang, Tang, Guangxian, Lin, Fengbin, Chen, Shida, Song, Yunhe, Li, Fei, Wang, Wei, Zhao, Zhenni, Gao, Xinbo, Wang, Peiyuan, Jin, Ling, Liu, Yuhong, Chen, Meiling, Liang, Xiaohong, Yang, Bin, Ning, Guili, Cheng, Ching-Yu, Healey, Paul R., Park, Ki Ho, Zangwill, Linda M., Aung, Tin, Ohno-Matsui, Kyoko, Jonas, Jost B., Weinreb, Robert N., Zhang, Xiulan

Source: In Ophthalmology July 2022 129(7):803-812

The APOE E4 Allele Is Associated with Faster Rates of Neuroretinal Thinning in a Prospective Cohort Study of Suspect and Early Glaucoma

Authors: Mullany, Sean, Marshall, Henry, Diaz-Torres, Santiago, Berry, Ella C., Schmidt, Joshua M., Thomson, Daniel, Qassim, Ayub, To, Minh-Son, Dimasi, David, Kuot, Abraham, Knight, Lachlan S.W., Hollitt, Georgina, Kolovos, Antonia, Schulz, Angela, Lake, Stewart, Mills, Richard A., Agar, Ashish, Galanopoulos, Anna, Landers, John, Mitchell, Paul, Healey, Paul R., Graham, Stuart L., Hewitt, Alex W., Souzeau, Emmanuelle, Hassall, Mark M., Klebe, Sonja, MacGregor, Stuart, Gharahkhani, Puya, Casson, Robert J., Siggs, Owen M., Craig, Jamie E.

Source: In Ophthalmology Science June 2022 2(2)

Genetic Risk of Cardiovascular Disease Is Associated with Macular Ganglion Cell–Inner Plexiform Layer Thinning in an Early Glaucoma Cohort

Authors: Marshall, Henry, Mullany, Sean, Han, Xikun, Berry, Ella C., Hassall, Mark M., Qassim, Ayub, Nguyen, Thi, Hollitt, Georgina L., Knight, Lachlan S.W., Ridge, Bronwyn, Schmidt, Joshua, Crowley, Caroline, Schulz, Angela, Mills, Richard A., Agar, Ashish, Galanopoulos, Anna, Landers, John, Healey, Paul R., Graham, Stuart L., Hewitt, Alex W., Casson, Robert J., MacGregor, Stuart, Siggs, Owen M., Craig, Jamie E.

Source: In Ophthalmology Science March 2022 2(1)

A Polygenic Risk Score Predicts Intraocular Pressure Readings Outside Office Hours and Early Morning Spikes as Measured by Home Tonometry

Authors: Qassim, Ayub, Mullany, Sean, Awadalla, Mona S., Hassall, Mark M., Nguyen, Thi, Marshall, Henry, Kolovos, Antonia, Schulz, Angela M., Han, Xikun, Gharahkhani, Puya, Galanopoulos, Anna, Agar, Ashish, Healey, Paul R., Hewitt, Alex W., Landers, John, Casson, Robert J., Graham, Stuart L., MacGregor, Stuart, Souzeau, Emmanuelle, Siggs, Owen M., Craig, Jamie E.

Source: In Ophthalmology Glaucoma July-August 2021 4(4):411-420

Corneal Stiffness Parameters Are Predictive of Structural and Functional Progression in Glaucoma Suspect Eyes

Authors: Qassim, Ayub, Mullany, Sean, Abedi, Farshad, Marshall, Henry, Hassall, Mark M., Kolovos, Antonia, Knight, Lachlan S.W., Nguyen, Thi, Awadalla, Mona S., Chappell, Angela, Schulz, Angela M., Galanopoulos, Anna, Agar, Ashish, Healey, Paul R., Hewitt, Alex W., Graham, Stuart L., Landers, John, Casson, Robert J., Siggs, Owen M., Craig, Jamie E.

Source: In Ophthalmology July 2021 128(7):993-1004

Cardiovascular Disease Predicts Structural and Functional Progression in Early Glaucoma

Authors: Marshall, Henry, Mullany, Sean, Qassim, Ayub, Siggs, Owen, Hassall, Mark, Ridge, Bronwyn, Nguyen, Thi, Awadalla, Mona, Andrew, Nicholas H., Healey, Paul R., Agar, Ashish, Galanopoulos, Anna, Hewitt, Alex W., MacGregor, Stuart, Graham, Stuart L., Mills, Richard, Shulz, Angela, Landers, John, Casson, Robert J., Craig, Jamie E.

Source: In Ophthalmology January 2021 128(1):58-69

EFOCUS 2: A randomised crossover trial of smartphone fundoscopy and direct ophthalmoscopy aiming to improve optic disc interpretation by medical students with e‐learning support

Authors: Dunn, Hamish P., Marks, Samuel, Teo, Kai Z., Dunn, Stewart M., Healey, Paul R., White, Andrew J.

Source: Clinical & experimental ophthalmology. 49(7):704-713

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Standalone iStent Trabecular Micro-bypass Glaucoma Surgery: A Systematic Review and Meta-Analysis

Authors: Healey, Paul R., Clement, Colin I., Kerr, Nathan M., Tilden, Dominic, Aghajanian, Lara

Source: Journal of glaucoma. 30(7):606-620

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An Intraocular Pressure Polygenic Risk Score Stratifies Multiple Primary Open-Angle Glaucoma Parameters Including Treatment Intensity

Authors: Qassim, Ayub, Souzeau, Emmanuelle, Siggs, Owen M., Hassall, Mark M., Han, Xikun, Griffiths, Helen L., Frost, N. Andrew, Vallabh, Neeru A., Kirwan, James F., Menon, Geeta, Cree, Angela J., Galanopoulos, Anna, Agar, Ashish, Healey, Paul R., Graham, Stuart L., Landers, John, Casson, Robert J., Gharahkhani, Puya, Willoughby, Colin E., Hewitt, Alex W., Lotery, Andrew J., MacGregor, Stuart, Craig, Jamie E.

Source: In Ophthalmology July 2020 127(7):901-907

Fast Facts: Glaucoma

Authors: Healey, Paul R., Thomas, Ravi

Resource Type: eBook.

Subjects: Glaucoma

Categories: MEDICAL / Ophthalmology

Macular Ganglion Cell–Inner Plexiform Layer Loss Precedes Peripapillary Retinal Nerve Fiber Layer Loss in Glaucoma with Lower Intraocular Pressure

Authors: Marshall, Henry N., Andrew, Nicholas H., Hassall, Mark, Qassim, Ayub, Souzeau, Emmanuelle, Ridge, Bronwyn, Nguyen, Thi, Fitzgerald, Jude, Awadalla, Mona S., Burdon, Kathryn P., Healey, Paul R., Agar, Ashish, Galanopoulos, Anna, Hewitt, Alex W., Graham, Stuart L., Landers, John, Casson, Robert J., Craig, Jamie E.

Source: In Ophthalmology August 2019 126(8):1119-1130

Effect of phacoemulsification cataract surgery on intraocular pressure in early glaucoma: A prospective multi‐site study

Authors: Qassim, Ayub, Walland, Mark J., Landers, John, Awadalla, Mona, Nguyen, Thi, Loh, Jason, Schulz, Angela M., Ridge, Bronwyn, Galanopoulos, Anna, Agar, Ashish, Hewitt, Alex W., Graham, Stuart L., Healey, Paul R., Casson, Robert J., Craig, Jamie E.

Source: Clinical & experimental ophthalmology. 48(4):442-449

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Myocilin Predictive Genetic Testing for Primary Open-Angle Glaucoma Leads to Early Identification of At-Risk Individuals

Authors: Souzeau, Emmanuelle, Tram, Kien Hou, Witney, Martin, Ruddle, Jonathan B., Graham, Stuart L., Healey, Paul R., Goldberg, Ivan, Mackey, David A., Hewitt, Alex W., Burdon, Kathryn P., Craig, Jamie E.

Source: In Ophthalmology March 2017 124(3):303-309

DNA methylation at the 9p21 glaucoma susceptibility locus is associated with normal-tension glaucoma

Authors: Burdon, Kathryn P., Awadalla, Mona S., Mitchell, Paul, Wang, Jie Jin, White, Andrew, Keane, Miriam C., Souzeau, Emmanuelle, Graham, Stuart L., Goldberg, Ivan, Healey, Paul R., Landers, John, Mills, Richard A. D., Best, Stephen, Hewitt, Alex W., Sharma, Shiwani, Craig, Jamie E.

Source: Ophthalmic genetics. 39(2):221-227

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Association of Open-Angle Glaucoma Loci With Incident Glaucoma in the Blue Mountains Eye Study

Authors: Burdon, Kathryn P., Mitchell, Paul, Lee, Anne, Healey, Paul R., White, Andrew J.R., Rochtchina, Elena, Thomas, Peter B.M., Wang, Jie Jin, Craig, Jamie E.

Source: In American Journal of Ophthalmology January 2015 159(1):31-36