Development of a deep learning algorithm for Paneth cell density quantification for inflammatory bowel disease

Authors: Kang, Liang-I, Sarullo, Kathryn, Marsh, Jon N., Lu, Liang, Khonde, Pooja, Ma, Changqing, Haritunians, Talin, Mujukian, Angela, Mengesha, Emebet, McGovern, Dermot P.B., Stappenbeck, Thaddeus S., Swamidass, S. Joshua, Liu, Ta-Chiang

Source: In eBioMedicine December 2024 110

Comprehensive Association Analyses of Extraintestinal Manifestations in Inflammatory Bowel Disease

Authors: Khrom, Michelle, Long, Millie, Dube, Shishir, Robbins, Lori, Botwin, Gregory J., Yang, Shaohong, Mengesha, Emebet, Li, Dalin, Naito, Takeo, Bonthala, Nirupama N., Ha, Christina, Melmed, Gil, Rabizadeh, Shervin, Syal, Gaurav, Vasiliauskas, Eric, Ziring, David, Brant, Steven R., Cho, Judy, Duerr, Richard H., Rioux, John, Schumm, Phil, Silverberg, Mark, Ananthakrishnan, Ashwin N., Faubion, William A., Jabri, Bana, Lira, Sergio A., Newberry, Rodney D., Sandler, Robert S., Xavier, Ramnik J., Kugathasan, Subra, Hercules, David, Targan, Stephan R., Sartor, R. Balfour, Haritunians, Talin, McGovern, Dermot P.B.

Source: In Gastroenterology July 2024 167(2):315-332

Allogeneic bone marrow transplantation for patients with treatment-refractory Crohn's Disease

Authors: McDonald, George B. ^{a, b, ∗}, Landsverk, Ole J.B. ^c, McGovern, Dermot P.B. ^d, Aasebø, Anders ^c, Paulsen, Vemund ^e, Haritunians, Talin ^d, Reims, Henrik M. ^c, McLaughlin, Bernadette M. ^a, Zisman, Timothy ^b, Li, Dalin ^d, Elholm, Elisabeth T.M.M. ^{a, g}, Jahnsen, Frode L. ^f, Georges, George E. ^{a, b}, Gedde-Dahl, Tobias ^g

Source: In Heliyon 15 January 2024 10(1)

Ancestral Diversity in Pharmacogenomics Affects Treatment for Hispanic/Latine Populations With Inflammatory Bowel Disease

Authors: Ioannou, Stephanie, Beecham, Ashley, Gomez, Lissette, Dauer, Ryan, Khakoo, Nidah, Pascual, Lauren, Quintero, Maria, Lopez, Joanna, Leavitt, James S., Solis, Norma, Ortega, Mailenys, Deshpande, Amar R., Kerman, David H., Proksell, Siobhan, Torres, Esther A., Haritunians, Talin, Li, Dalin, Abreu, Maria T., McGovern, Dermott P.B., McCauley, Jacob L., Damas, Oriana M.

Source: In Clinical Gastroenterology and Hepatology

Potential determinants of low circulating glucagon‐like peptide 2 concentrations in Zambian children with non‐responsive stunting

Authors: Besa, Ellen, Tembo, Mizinga Jacqueline, Mulenga, Chola, Mweetwa, Monica, Choudhry, Naheed, Chandwe, Kanta, Storer, Chad, Head, Richard, Amadi, Beatrice, Haritunians, Talin, McGovern, Dermot, Kwenda, Geoffrey, Peiris, Madusha, Kelly, Paul

Source: Experimental physiology. 108(4):568-580

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182005627.0x000001&indx=1&recIds=ETOCvdc_100182005627.0x000001

Profiling the inflammatory bowel diseases using genetics, serum biomarkers, and smoking information

Authors: Liu, Ruize, Li, Dalin, Haritunians, Talin, Ruan, Yunfeng, Daly, Mark J., Huang, Hailiang, McGovern, Dermot P.B.

Source: In iScience 20 October 2023 26(10)

HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis

Authors: Akar, Alaa, Flemming, Cornelius, Felix, Flomm, Flosbach, Markus, Jäger, Julia, Jeromin, Niklas, Jung, Johannes, Ohms, Mareike, Reinshagen, Konrad, Rische, Johann, Sagebiel, Adrian, Sandfort, Deborah, Steinert, Fenja, Tomuschat, Christian, Wesche, Jasmin, Shifteh Abedian, Abraham, Clara, Achkar, Jean-Paul, Ahmad, Tariq, Alberts, Rudi, Alizadeh, Behrooz, Amininejad, Leila, Ananthakrishnan, Ashwin N., Andersen, Vibeke, Anderson, Carl A., Andrews, Jane M., Annese, Vito, Aumais, Guy, Baidoo, Leonard, Baldassano, Robert N., Bampton, Peter A., Barclay, Murray, Barrett, Jeffrey C., Bethge, Johannes, Bewshea, Claire, Bis, Joshua C., Bitton, Alain, BK, Thelma, Boucher, Gabrielle, Brain, Oliver, Brand, Stephan, Brant, Steven R., Cheon, Jae Hee, Chew, Angela, Cho, Judy H., Cleynen, Isabelle, Cohain, Ariella, Cooney, Rachel, Croft, Anthony, Daly, Mark J., D'Amato, Mauro, Danese, Silvio, Daryani, Naser Ebrahim, Datta, Lisa Wu, Degenhardt, Frauke, Denapiene, Goda, Denson, Lee A., Devaney, Kathy L., Dewit, Olivier, D'Inca, Renata, Drummond, Hazel E., Dubinsky, Marla, Duerr, Richard H., Edwards, Cathryn, Ellinghaus, David, Ellul, Pierre, Esaki, Motohiro, Essers, Jonah, Ferguson, Lynnette R., Festen, Eleonora A., Fleshner, Philip, Florin, Tim, Franchimont, Denis, Franke, Andre, Fuyuno, Yuta, Gearry, Richard, Georges, Michel, Gieger, Christian, Glas, Jürgen, Goyette, Philippe, Green, Todd, Griffiths, Anne M., Guthery, Stephen L., Hakonarson, Hakon, Halfvarson, Jonas, Hanigan, Katherine, Haritunians, Talin, Hart, Ailsa, Hawkey, Chris, Hayward, Nicholas K., Hedl, Matija, Henderson, Paul, Hold, Georgina L., Hong, Myhunghee, Hu, Xinli, Huang, Hailiang, Hugot, Jean-Pierre, Hui, Ken Y., Imielinski, Marcin, Jazayeri, Omid, Jonaitis, Laimas, Jostins, Luke, Juyal, Garima, Chandra Juyal, Ramesh, Kalla, Rahul, Karlsen, Tom H., Kennedy, Nicholas A., Khan, Mohammed Azam, Kim, Won Ho, Kitazono, Takanari, Kiudelis, Gediminas, Kubo, Michiaki, Kugathasan, Subra, Kupcinskas, Limas, Lamb, Christopher A., de Lange, Katrina M., Latiano, Anna, Laukens, Debby, Lawrance, Ian C., Lee, James C., Lees, Charlie W., Leja, Marcis, Lewis, Nina, Van Limbergen, Johan, Lionetti, Paolo, Liu, Jimmy Z., Louis, Edouard, Luo, Yang, Mahy, Gillian, Malekzadeh, Masoud Mohammad, Malekzadeh, Reza, Mansfield, John, Marriott, Suzie, Massey, Dunecan, Mathew, Christopher G., Matsui, Toshiyuki, McGovern, Dermot P.B., van der Meulen, Andrea, Midha, Vandana, Milgrom, Raquel, Mirzaei, Samaneh, Mitrovic, Mitja, Montgomery, Grant W., Mowat, Craig, Müller, Christoph, Newman, William G., Ng, Aylwin, Ng, Siew C., Evelyn Ng, Sok Meng, Nikolaus, Susanna, Ning, Kaida, Nöthen, Markus, Oikonomou, Ioannis, Okou, David, Orchard, Timothy R., Palmieri, Orazio, Parkes, Miles, Phillips, Anne, Ponsioen, Cyriel Y., Potocnik, Urõs, Poustchi, Hossein, Prescott, Natalie J., Proctor, Deborah D., Radford-Smith, Graham, Rahier, Jean- Francois, Regueiro, Miguel, Reinisch, Walter, Rieder, Florian, Rioux, John D., Roberts, Rebecca, Rogler, Gerhard, Russell, Richard K., Sanderson, Jeremy D., Sans, Miquel, Satsangi, Jack, Schadt, Eric E., Scharl, Michael, Schembri, John, Schreiber, Stefan, Schumm, L. Philip, Scott, Regan, Seielstad, Mark, Shah, Tejas, Sharma, Yashoda, Silverberg, Mark S., Simmons, Alison, Simms, Lisa A., Singh, Abhey, Skieceviciene, Jurgita, van Sommeren, Suzanne, Song, Kyuyoung, Sood, Ajit, Spain, Sarah L., Steinhart, A. Hillary, Stempak, Joanne M., Stronati, Laura, Sung, Joseph J.Y., Targan, Stephan R., Taylor, Kirstin M., Theatre, Emilie, Torkvist, Leif, Torres, Esther A., Tremelling, Mark, Uhlig, Holm H., Umeno, Junji, Vahedi, Homayon, Vasiliauskas, Eric, Velde, Anje ter, Ventham, Nicholas T., Vermeire, Severine, Verspaget, Hein W., De Vos, Martine, Walters, Thomas, Wang, Kai, Wang, Ming-Hsi, Weersma, Rinse K., Wei, Zhi, Whiteman, David, Wijmenga, Cisca, Wilson, David C., Winkelmann, Juliane, Wong, Sunny H., Xavier, Ramnik J., Yamazaki, Keiko, Yang, Suk-Kyun, Ye, Byong Duk, Zeissig, Sebastian, Zhang, Bin, Zhang, Clarence K., Zhang, Hu, Zhang, Wei, Zhao, Hongyu, Zhao, Zhen Z., Baumdick, Martin E., Niehrs, Annika, Schwerk, Maria, Hinrichs, Ole, Jordan-Paiz, Ana, Padoan, Benedetta, Wegner, Lucy H.M., Schloer, Sebastian, Zecher, Britta F., Malsy, Jakob, Joshi, Vinita R., Illig, Christin, Schröder-Schwarz, Jennifer, Möller, Kimberly J., Martin, Maureen P., Yuki, Yuko, Ozawa, Mikki, Sauter, Jürgen, Schmidt, Alexander H., Perez, Daniel, Giannou, Anastasios D., Carrington, Mary, Davis, Randall S., Schumacher, Udo, Sauter, Guido, Huber, Samuel, Puelles, Victor G., Melling, Nathaniel, Altfeld, Marcus, Bunders, Madeleine J.

Source: In Gastroenterology October 2023 165(4):946-962

Histo-Blood Group Antigens, Enteropathogen Carriage and Environmental Enteropathy in Stunted Zambian Children

Authors: Chandwe, Kanta, Zyambo, Kanekwa, Mulenga, Chola, Haritunians, Talin, Amadi, Beatrice, Kosek, Margaret, Heimburger, Douglas C., McGovern, Dermot, Kelly, Paul

Source: Journal of pediatric gastroenterology and nutrition. 74(4):529-534

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100156359656.0x000001&indx=1&recIds=ETOCvdc_100156359656.0x000001

Eleven Grand Challenges for Inflammatory Bowel Disease Genetics and Genomics.

Authors: Gibson, Greg, Rioux, John D, Cho, Judy H, Haritunians, Talin, Thoutam, Akshaya, Abreu, Maria T, Brant, Steven R, Kugathasan, Subra, McCauley, Jacob L, Silverberg, Mark, McGovern, Dermot

Source: Inflammatory Bowel Diseases; Jan2025, Vol. 31 Issue 1, p272-284, 13p

Stratification of risk of progression to colectomy in ulcerative colitis via measured and predicted gene expression

Authors: Mo, Angela, Nagpal, Sini, Gettler, Kyle, Haritunians, Talin, Giri, Mamta, Haberman, Yael, Karns, Rebekah, Prince, Jarod, Arafat, Dalia, Hsu, Nai-Yun, Chuang, Ling-Shiang, Argmann, Carmen, Kasarskis, Andrew, Suarez-Farinas, Mayte, Gotman, Nathan, Mengesha, Emebet, Venkateswaran, Suresh, Rufo, Paul A., Baker, Susan S., Sauer, Cary G., Markowitz, James, Pfefferkorn, Marian D., Rosh, Joel R., Boyle, Brendan M., Mack, David R., Baldassano, Robert N., Shah, Sapana, LeLeiko, Neal S., Heyman, Melvin B., Griffiths, Anne M., Patel, Ashish S., Noe, Joshua D., Davis Thomas, Sonia, Aronow, Bruce J., Walters, Thomas D., McGovern, Dermot P.B., Hyams, Jeffrey S., Kugathasan, Subra, Cho, Judy H., Denson, Lee A., Gibson, Greg

Source: In The American Journal of Human Genetics 2 September 2021 108(9):1765-1779

Crohn's disease-associated ATG16L1 T300A genotype is associated with improved survival in gastric cancer

Authors: Ma, Changqing, Storer, Chad E., Chandran, Uma, LaFramboise, William A., Petrosko, Patricia, Frank, Madison, Hartman, Douglas J., Pantanowitz, Liron, Haritunians, Talin, Head, Richard D., Liu, Ta-Chiang

Source: In EBioMedicine May 2021 67

Inflamed Ulcerative Colitis Regions Associated With MRGPRX2-Mediated Mast Cell Degranulation and Cell Activation Modules, Defining a New Therapeutic Target

Authors: Chen, Ernie, Chuang, Ling-shiang, Giri, Mamta, Villaverde, Nicole, Hsu, Nai-yun, Sabic, Ksenija, Joshowitz, Sari, Gettler, Kyle, Nayar, Shikha, Chai, Zhi, Alter, Isaac L., Chasteau, Colleen C., Korie, Ujunwa M., Dzedzik, Siarhei, Thin, Tin Htwe, Jain, Aayushee, Moscati, Arden, Bongers, Gerardus, Duerr, Richard H., Silverberg, Mark S., Brant, Steven R., Rioux, John D., Peter, Inga, Schumm, L. Philip, Haritunians, Talin, McGovern, Dermot P., Itan, Yuval, Cho, Judy H.

Source: In Gastroenterology April 2021 160(5):1709-1724

Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry

Authors: Graff, Mariaelisa, Justice, Anne E., Young, Kristin L., Marouli, Eirini, Zhang, Xinruo, Fine, Rebecca S., Lim, Elise, Buchanan, Victoria, Rand, Kristin, Feitosa, Mary F., Wojczynski, Mary K., Yanek, Lisa R., Shao, Yaming, Rohde, Rebecca, Adeyemo, Adebowale A., Aldrich, Melinda C., Allison, Matthew A., Ambrosone, Christine B., Ambs, Stefan, Amos, Christopher, Arnett, Donna K., Atwood, Larry, Bandera, Elisa V., Bartz, Traci, Becker, Diane M., Berndt, Sonja I., Bernstein, Leslie, Bielak, Lawrence F., Blot, William J., Bottinger, Erwin P., Bowden, Donald W., Bradfield, Jonathan P., Brody, Jennifer A., Broeckel, Ulrich, Burke, Gregory, Cade, Brian E., Cai, Qiuyin, Caporaso, Neil, Carlson, Chris, Carpten, John, Casey, Graham, Chanock, Stephen J., Chen, Guanjie, Chen, Minhui, Chen, Yii-Der I., Chen, Wei-Min, Chesi, Alessandra, Chiang, Charleston W.K., Chu, Lisa, Coetzee, Gerry A., Conti, David V., Cooper, Richard S., Cushman, Mary, Demerath, Ellen, Deming, Sandra L., Dimitrov, Latchezar, Ding, Jingzhong, Diver, W. Ryan, Duan, Qing, Evans, Michele K., Falusi, Adeyinka G., Faul, Jessica D., Fornage, Myriam, Fox, Caroline, Freedman, Barry I., Garcia, Melissa, Gillanders, Elizabeth M., Goodman, Phyllis, Gottesman, Omri, Grant, Struan F.A., Guo, Xiuqing, Hakonarson, Hakon, Haritunians, Talin, Harris, Tamara B., Harris, Curtis C., Henderson, Brian E., Hennis, Anselm, Hernandez, Dena G., Hirschhorn, Joel N., McNeill, Lorna Haughton, Howard, Timothy D., Howard, Barbara, Hsing, Ann W., Hsu, Yu-Han H., Hu, Jennifer J., Huff, Chad D., Huo, Dezheng, Ingles, Sue A., Irvin, Marguerite R., John, Esther M., Johnson, Karen C., Jordan, Joanne M., Kabagambe, Edmond K., Kang, Sun J., Kardia, Sharon L., Keating, Brendan J., Kittles, Rick A., Klein, Eric A., Kolb, Suzanne, Kolonel, Laurence N., Kooperberg, Charles, Kuller, Lewis, Kutlar, Abdullah, Lange, Leslie, Langefeld, Carl D., Le Marchand, Loic, Leonard, Hampton, Lettre, Guillaume, Levin, Albert M., Li, Yun, Li, Jin, Liu, Yongmei, Liu, Youfang, Liu, Simin, Lohman, Kurt, Lotay, Vaneet, Lu, Yingchang, Maixner, William, Manson, JoAnn E., McKnight, Barbara, Meng, Yan, Monda, Keri L., Monroe, Kris, Moore, Jason H., Mosley, Thomas H., Mudgal, Poorva, Murphy, Adam B., Nadukuru, Rajiv, Nalls, Mike A., Nathanson, Katherine L., Nayak, Uma, N’Diaye, Amidou, Nemesure, Barbara, Neslund-Dudas, Christine, Neuhouser, Marian L., Nyante, Sarah, Ochs-Balcom, Heather, Ogundiran, Temidayo O., Ogunniyi, Adesola, Ojengbede, Oladosu, Okut, Hayrettin, Olopade, Olufunmilayo I., Olshan, Andrew, Padhukasahasram, Badri, Palmer, Julie, Palmer, Cameron D., Palmer, Nicholette D., Papanicolaou, George, Patel, Sanjay R., Pettaway, Curtis A., Peyser, Patricia A., Press, Michael F., Rao, D.C., Rasmussen-Torvik, Laura J., Redline, Susan, Reiner, Alex P., Rhie, Suhn K., Rodriguez-Gil, Jorge L., Rotimi, Charles N., Rotter, Jerome I., Ruiz-Narvaez, Edward A., Rybicki, Benjamin A., Salako, Babatunde, Sale, Michele M., Sanderson, Maureen, Schadt, Eric, Schreiner, Pamela J., Schurmann, Claudia, Schwartz, Ann G., Shriner, Daniel A., Signorello, Lisa B., Singleton, Andrew B., Siscovick, David S., Smith, Jennifer A., Smith, Shad, Speliotes, Elizabeth, Spitz, Margaret, Stanford, Janet L., Stevens, Victoria L., Stram, Alex, Strom, Sara S., Sucheston, Lara, Sun, Yan V., Tajuddin, Salman M., Taylor, Herman, Taylor, Kira, Tayo, Bamidele O., Thun, Michael J., Tucker, Margaret A., Vaidya, Dhananjay, Van Den Berg, David J., Vedantam, Sailaja, Vitolins, Mara, Wang, Zhaoming, Ware, Erin B., Wassertheil-Smoller, Sylvia, Weir, David R., Wiencke, John K., Williams, Scott M., Williams, L. Keoki, Wilson, James G., Witte, John S., Wrensch, Margaret, Wu, Xifeng, Yao, Jie, Zakai, Neil, Zanetti, Krista, Zemel, Babette S., Zhao, Wei, Zhao, Jing Hua, Zheng, Wei, Zhi, Degui, Zhou, Jie, Zhu, Xiaofeng, Ziegler, Regina G., Zmuda, Joe, Zonderman, Alan B., Psaty, Bruce M., Borecki, Ingrid B., Cupples, L. Adrienne, Liu, Ching-Ti, Haiman, Christopher A., Loos, Ruth, Ng, Maggie C.Y., North, Kari E.

Source: In The American Journal of Human Genetics 1 April 2021 108(4):564-582

Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease

Authors: Somineni, Hari K., Nagpal, Sini, Venkateswaran, Suresh, Cutler, David J., Okou, David T., Haritunians, Talin, Simpson, Claire L., Begum, Ferdouse, Datta, Lisa W., Quiros, Antonio J., Seminerio, Jenifer, Mengesha, Emebet, Alexander, Jonathan S., Baldassano, Robert N., Dudley-Brown, Sharon, Cross, Raymond K., Dassopoulos, Themistocles, Denson, Lee A., Dhere, Tanvi A., Iskandar, Heba, Dryden, Gerald W., Hou, Jason K., Hussain, Sunny Z., Hyams, Jeffrey S., Isaacs, Kim L., Kader, Howard, Kappelman, Michael D., Katz, Jeffry, Kellermayer, Richard, Kuemmerle, John F., Lazarev, Mark, Li, Ellen, Mannon, Peter, Moulton, Dedrick E., Newberry, Rodney D., Patel, Ashish S., Pekow, Joel, Saeed, Shehzad A., Valentine, John F., Wang, Ming-Hsi, McCauley, Jacob L., Abreu, Maria T., Jester, Traci, Molle-Rios, Zarela, Palle, Sirish, Scherl, Ellen J., Kwon, John, Rioux, John D., Duerr, Richard H., Silverberg, Mark S., Zwick, Michael E., Stevens, Christine, Daly, Mark J., Cho, Judy H., Gibson, Greg, McGovern, Dermot P.B., Brant, Steven R., Kugathasan, Subra

Source: In The American Journal of Human Genetics 4 March 2021 108(3):431-445

Altered Intestinal ACE2 Levels Are Associated With Inflammation, Severe Disease, and Response to Anti-Cytokine Therapy in Inflammatory Bowel Disease

Authors: Potdar, Alka A., Dube, Shishir, Naito, Takeo, Li, Katherine, Botwin, Gregory, Haritunians, Talin, Li, Dalin, Casero, David, Yang, Shaohong, Bilsborough, Janine, Perrigoue, Jacqueline G., Denson, Lee A., Daly, Mark, Targan, Stephan R., Fleshner, Phillip, Braun, Jonathan, Kugathasan, Subra, Stappenbeck, Thaddeus S., McGovern, Dermot P.B.

Source: In Gastroenterology February 2021 160(3):809-822

Prevalence and Effect of Genetic Risk of Thromboembolic Disease in Inflammatory Bowel Disease

Authors: Cho, Judy, Silverberg, Mark, Duerr, Richard, Rioux, John, Brant, Steven, Schumm, Philip, Naito, Takeo, Botwin, Gregory J., Haritunians, Talin, Li, Dalin, Yang, Shaohong, Khrom, Michelle, Braun, Jonathan, Abbou, Lisa, Mengesha, Emebet, Stevens, Christine, Masamune, Atsushi, Daly, Mark, McGovern, Dermot P.B.

Source: In Gastroenterology February 2021 160(3):771-780

Genetic variation in environmental enteropathy and stunting in Zambian children: A pilot genome wide association study using the H3Africa chip.

Authors: Mweetwa, Monica N.^1,2 (AUTHOR) monica@tropgan.net, Haritunians, Talin³ (AUTHOR), Dube, Shishir³ (AUTHOR), Chandwe, Kanta^1,4 (AUTHOR), Amadi, Beatrice^1,4 (AUTHOR), Zyambo, Kanekwa¹ (AUTHOR), Liu, Ta-Chiang⁵ (AUTHOR), McGovern, Dermot³ (AUTHOR), Kelly, Paul^1,5,6 (AUTHOR)

Source: PLoS ONE. 9/27/2023, Vol. 18 Issue 9, p1-15. 15p.

Subject Terms: *STUNTED growth, *GENOME-wide association studies, *GENETIC variation, *SINGLE nucleotide polymorphisms, *INTESTINAL diseases, *CELIAC disease, *MALNUTRITION in children, *IMMUNOGLOBULINS

Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations

Authors: Degenhardt, Frauke, Mayr, Gabriele, Wendorff, Mareike, Boucher, Gabrielle, Ellinghaus, Eva, Ellinghaus, David, ElAbd, Hesham, Rosati, Elisa, Hübenthal, Matthias, Juzenas, Simonas, Abedian, Shifteh, Vahedi, Homayon, Thelma, B K, Yang, Suk-Kyun, Ye, Byong Duk, Cheon, Jae Hee, Datta, Lisa Wu, Daryani, Naser Ebrahim, Ellul, Pierre, Esaki, Motohiro, Fuyuno, Yuta, McGovern, Dermot P B, Haritunians, Talin, Hong, Myhunghee, Juyal, Garima, Jung, Eun Suk, Kubo, Michiaki, Kugathasan, Subra, Lenz, Tobias L, Leslie, Stephen, Malekzadeh, Reza, Midha, Vandana, Motyer, Allan, Ng, Siew C, Okou, David T, Raychaudhuri, Soumya, Schembri, John, Schreiber, Stefan, Song, Kyuyoung, Sood, Ajit, Takahashi, Atsushi, Torres, Esther A, Umeno, Junji, Alizadeh, Behrooz Z, Weersma, Rinse K, Wong, Sunny H, Yamazaki, Keiko, Karlsen, Tom H, Rioux, John D, Brant, Steven R, Franke, Andre

Source: Human molecular genetics. 30(5):356-369

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121120138.0x000001&indx=1&recIds=ETOCvdc_100121120138.0x000001

Ileal Paneth Cell Phenotype is a Cellular Biomarker for Pouch Complications in Ulcerative Colitis.

Authors: Ma, Changqing, Haritunians, Talin, Gremida, Anas K, Syal, Gaurav, Shah, Janaki, Yang, Shaohong, Rivers, Claudia Ramos Del Aguila de, Storer, Chad E, Chen, Ling, Mengesha, Emebet, Mujukian, Angela, Hanna, Mary, Fleshner, Phillip, Binion, David G, VanDussen, Kelli L, Stappenbeck, Thaddeus S, Head, Richard D, Ciorba, Matthew A, McGovern, Dermot P B, Liu, Ta-Chiang

Source: Journal of Crohn's & Colitis; Dec2024, Vol. 18 Issue 12, p2010-2022, 13p

Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction.

Authors: Sun, Shengxiang, Hodel, Miki, Wang, Xiang, De Vicente, Javier, Haritunians, Talin, Debebe, Anketse, Hung, Chen-Ting, Ma, Changqing, Malique, Atika, Nguyen, Hoang N., Agam, Maayan, Maloney, Michael T., Goo, Marisa S., Kluss, Jillian H., Mishra, Richa, Frein, Jennifer, Foster, Amanda, Ballentine, Samuel, Pandey, Uday, Kern, Justin

Source: Science Immunology; 2024, Vol. 9 Issue 101, p1-13, 13p

Subject Terms: DARDARIN, CROHN'S disease, PARKINSON'S disease, CIGARETTE smoke, SMOKING