Regulation of human GnT-IV family activity by the lectin domain

Authors: Osada, Naoko, Nagae, Masamichi, Yamasaki, Takahiro, Harduin-Lepers, Anne, Kizuka, Yasuhiko

Source: In Carbohydrate Research November 2024 545

Molecular dynamics simulations shed light into the donor substrate specificity of vertebrate poly-alpha-2,8-sialyltransferases ST8Sia IV

Authors: Teppa, Roxana Elin, Galuska, Sebastian Peter, Harduin-Lepers, Anne

Source: In BBA - General Subjects August 2024 1868(8)

LacdiNAc synthase B4GALNT3 has a unique PA14 domain and suppresses N-glycan capping

Authors: Tokoro, Yuko, Nagae, Masamichi, Nakano, Miyako, Harduin-Lepers, Anne, Kizuka, Yasuhiko

Source: In Journal of Biological Chemistry July 2024 300(7)

Cadmium induces physiological and behavioral changes associated with 180 kDa NCAM lower expression and higher polysialic acid, in the African clawed Xenopus laevis tadpoles

Authors: Marchand, Guillaume, Fliniaux, Ingrid, Titran, Pauline, Takeda Uchimura, Yoshiko, Bodart, Jean-François, Harduin Lepers, Anne, Cailliau, Katia, Marin, Matthieu

Source: In Ecotoxicology and Environmental Safety 15 March 2024 273

A Rapid and Sensitive MicroPlate Assay (MPSA) Using an Alkyne‐Modified CMP‐Sialic Acid Donor to Evaluate Human Sialyltransferase Specificity.

Authors: Clairene Filipe, Kiamungongo, Dangudubiyyam, Sushmaa, Lion, Cédric, Decloquement, Mathieu, Elin Teppa, Roxana, Biot, Christophe, Harduin‐Lepers, Anne

Source: ChemBioChem; 3/3/2025, Vol. 26 Issue 5, p1-7, 7p

Analysis of the proximal promoter of the human colon-specific B4GALNT2 (Sda synthase) gene: B4GALNT2 is transcriptionally regulated by ETS1

Authors: Wavelet-Vermuse, Cindy, Groux-Degroote, Sophie, Vicogne, Dorothée, Cogez, Virginie, Venturi, Giulia, Trinchera, Marco, Brysbaert, Guillaume, Krzewinski-Recchi, Marie-Ange, Hadj Bachir, Elsa, Schulz, Céline, Vincent, Audrey, Van Seuningen, Isabelle, Harduin-Lepers, Anne

Source: In BBA - Gene Regulatory Mechanisms November-December 2021 1864(11-12)

B4GALNT2 Controls Sda and SLex Antigen Biosynthesis in Healthy and Cancer Human Colon

Authors: Groux‐Degroote, Sophie, Vicogne, Dorothée, Cogez, Virginie, Schulz, Céline, Harduin‐Lepers, Anne

Source: Chembiochem. 22(24):3381-3390

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100147036378.0x000001&indx=1&recIds=ETOCvdc_100147036378.0x000001

Unliganded and CMP-Neu5Ac bound structures of human α-2,6-sialyltransferase ST6Gal I at high resolution

Authors: Harrus, Deborah, Harduin-Lepers, Anne, Glumoff, Tuomo

Source: In Journal of Structural Biology 1 November 2020 212(2)

Assembly of B4GALT1/ST6GAL1 heteromers in the Golgi membranes involves lateral interactions via highly charged surface domains

Alternate Title: Molecular interactions between B4GALT1 and ST6GAL1 (English)

Authors: Khoder-Agha, Fawzi, Harrus, Deborah, Brysbaert, Guillaume, Lensink, Marc F., Harduin-Lepers, Anne, Glumoff, Tuomo, Kellokumpu, Sakari

Source: In Journal of Biological Chemistry 27 September 2019 294(39):14383-14393

A Golgi-associated redox switch regulates catalytic activation and cooperative functioning of ST6Gal-I with B4GalT-I

Authors: Hassinen, Antti, Khoder-Agha, Fawzi, Khosrowabadi, Elham, Mennerich, Daniela, Harrus, Deborah, Noel, Maxence, Dimova, Elitsa Y., Glumoff, Tuomo, Harduin-Lepers, Anne, Kietzmann, Thomas, Kellokumpu, Sakari

Source: In Redox Biology June 2019 24

Mycobacterium bovis BCG infection alters the macrophage N-glycomeElectronic supplementary information (ESI) available. See DOI: 10.1039/c9mo00173e

Authors: Delannoy, Clément, Huang, Chin, Coddeville, Bernadette, Chen, Jian-You, Mouajjah, Dounia, Groux-Degroote, Sophie, Harduin-Lepers, Anne, Khoo, Kay-Hooi, Guerardel, Yann, Elass-Rochard, Elisabeth

Source: Molecular omics. 16(4):345-354

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108995482.0x000001&indx=1&recIds=ETOCvdc_100108995482.0x000001

Roles of GalNAc-disialyl Lactotetraosyl Antigens in Renal Cancer Cells

Authors: Tsuchida, Akiko, Senda, Motohiro, Ito, Akihiro, Saito, Seiichi, Kiso, Makoto, Ando, Takayuki, Harduin-Lepers, Anne, Matsuda, Akio, Furukawa, Keiko, Furukawa, Koichi

Source: Scientific reports. 8(1):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100136259103.0x000001&indx=1&recIds=ETOCvdc_100136259103.0x000001

Reconstruction of the sialylation pathway in the ancestor of eukaryotes

Authors: Petit, Daniel, Teppa, Elin, Cenci, Ugo, Ball, Steven, Harduin-Lepers, Anne

Source: Scientific reports. 8(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112267204.0x000001&indx=1&recIds=ETOCvdc_100112267204.0x000001

The extended cytoplasmic tail of the human B4GALNT2 is critical for its Golgi targeting and post‐Golgi sorting

Authors: Groux‐Degroote, Sophie, Schulz, Céline, Cogez, Virginie, Noël, Maxence, Portier, Lucie, Vicogne, Dorothée, Solorzano, Carlos, Dall'Olio, Fabio, Steenackers, Agata, Mortuaire, Marlène, Gonzalez‐Pisfil, Mariano, Henry, Mélanie, Foulquier, François, Héliot, Laurent, Harduin‐Lepers, Anne

Source: FEBS journal. 285(18):3442-3463

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083710696.0x000001&indx=1&recIds=ETOCvdc_100083710696.0x000001

MicroPlate Sialyltransferase Assay: A Rapid and Sensitive Assay Based on an Unnatural Sialic Acid Donor and Bioorthogonal Chemistry

Authors: Noel, Maxence, Gilormini, Pierre-André, Cogez, Virginie, Lion, Cédric, Biot, Christophe, Harduin-Lepers, Anne, Guérardel, Yann

Source: Bioconjugate chemistry. 29(10):3377-3384

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631363465&indx=1&recIds=ETOCRN631363465

B4GALNT2 gene expression controls the biosynthesis of Sda and sialyl Lewis X antigens in healthy and cancer human gastrointestinal tract

Authors: Groux-Degroote, Sophie, Wavelet, Cindy, Krzewinski-Recchi, Marie-Ange, Portier, Lucie, Mortuaire, Marlène, Mihalache, Adriana, Trinchera, Marco, Delannoy, Philippe, Malagolini, Nadia, Chiricolo, Mariella, Dall’Olio, Fabio, Harduin-Lepers, Anne

Source: In International Journal of Biochemistry and Cell Biology August 2014 53:442-449

The expanding roles of the Sda/Cad carbohydrate antigen and its cognate glycosyltransferase B4GALNT2

Authors: Dall'Olio, Fabio, Malagolini, Nadia, Chiricolo, Mariella, Trinchera, Marco, Harduin-Lepers, Anne

Source: In BBA - General Subjects January 2014 1840(1):443-453

Salmonid polysialyltransferases to generate a variety of sialic acid polymers.

Authors: Decloquement, Mathieu, Venuto, Marzia Tindara, Cogez, Virginie, Steinmetz, Anna, Schulz, Céline, Lion, Cédric, Noel, Maxence, Rigolot, Vincent, Teppa, Roxana Elin, Biot, Christophe, Rebl, Alexander, Galuska, Sebastian Peter, Harduin-Lepers, Anne

Source: Scientific Reports; 11/18/2023, Vol. 13 Issue 1, p1-14, 14p

Subject Terms: SIALIC acids, POLYMERS, BIOLOGICAL evolution, OVUM, HETEROCHAIN polymers, NEURAMINIDASE, MONOCLONAL antibodies

Unliganded and CMP-Neu5Ac bound structures of human α-2, 6-sialyltransferase ST6Gal I at high resolution

Authors: Harrus, Deborah, Harduin-Lepers, Anne, Glumoff, Tuomo

Source: Journal of structural biology. 212(2)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100109967876.0x000001&indx=1&recIds=ETOCvdc_100109967876.0x000001

Author Correction: Roles of GalNAc-disialyl Lactotetraosyl Antigens in Renal Cancer Cells

Authors: Tsuchida, Akiko, Senda, Motohiro, Ito, Akihiro, Saito, Seiichi, Kiso, Makoto, Ando, Takayuki, Harduin-Lepers, Anne, Matsuda, Akio, Furukawa, Keiko, Furukawa, Koichi

Source: Scientific reports. 10(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174699815.0x000001&indx=1&recIds=ETOCvdc_100174699815.0x000001