Engineering of protein nanopores for sequencing, chemical or protein sensing and disease diagnosis

Authors: Wang, Shaoying, Zhao, Zhengyi, Haque, Farzin, Guo, Peixuan

Source: In Current Opinion in Biotechnology June 2018 51:80-89

RNA Nanotherapeutics for the Amelioration of Astroglial Reactivity

Authors: Smith, Jayden A., Braga, Alice, Verheyen, Jeroen, Basilico, Silvia, Bandiera, Sara, Alfaro-Cervello, Clara, Peruzzotti-Jametti, Luca, Shu, Dan, Haque, Farzin, Guo, Peixuan, Pluchino, Stefano

Source: In Molecular Therapy - Nucleic Acids 2 March 2018 10:103-121

Favorable biodistribution, specific targeting and conditional endosomal escape of RNA nanoparticles in cancer therapy

Authors: Xu, Congcong, Haque, Farzin, Jasinski, Daniel L., Binzel, Daniel W., Shu, Dan, Guo, Peixuan

Source: In Cancer Letters 1 February 2018 414:57-70

Channel of viral DNA packaging motor for real time kinetic analysis of peptide oxidation states

Authors: Wang, Shaoying, Zhou, Zhi, Zhao, Zhengyi, Zhang, Hui, Haque, Farzin, Guo, Peixuan

Source: In Biomaterials May 2017 126:10-17

Methods for Single-Molecule Sensing and Detection Using Bacteriophage Phi29 DNA Packaging Motor

Authors: Haque, Farzin, Zhang, Hui, Wang, Shaoying, Chang, Chun-Li, Savran, Cagri, Guo, Peixuan

Source: Methods in molecular biology. 1805:423-450

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN617707730&indx=1&recIds=ETOCRN617707730

Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression

Authors: Pi, Fengmei, Binzel, Daniel, Lee, Tae, Li, Zhefeng, Sun, Meiyan, Rychahou, Piotr, Li, Hui, Haque, Farzin, Wang, Shaoying, Croce, Carlo, Guo, Bin, Evers, B., Guo, Peixuan

Source: Nature nanotechnology. 13(1):82-89

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099974132.0x000001&indx=1&recIds=ETOCvdc_100099974132.0x000001

Oriented single directional insertion of nanochannel of bacteriophage SPP1 DNA packaging motor into lipid bilayer via polar hydrophobicity

Authors: Zhou, Zhi, Ji, Zhouxiang, Wang, Shaoying, Haque, Farzin, Guo, Peixuan

Source: In Biomaterials October 2016 105:222-227

Controllable self-assembly of RNA dendrimers

Authors: Sharma, Ashwani, Haque, Farzin, Pi, Fengmei, Shlyakhtenko, Lyudmila S., Evers, B. Mark, Guo, Peixuan

Source: In Nanomedicine: Nanotechnology, Biology, and Medicine April 2016 12(3):835-844

RNA as a stable polymer to build controllable and defined nanostructures for material and biomedical applications

Authors: Li, Hui, Lee, Taek, Dziubla, Thomas, Pi, Fengmei, Guo, Sijin, Xu, Jing, Li, Chan, Haque, Farzin, Liang, Xing-Jie, Guo, Peixuan

Source: In Nano Today October 2015 10(5):631-655

Single pore translocation of folded, double-stranded, and tetra-stranded DNA through channel of bacteriophage phi29 DNA packaging motor

Authors: Haque, Farzin, Wang, Shaoying, Stites, Chris, Chen, Li, Wang, Chi, Guo, Peixuan

Source: In Biomaterials June 2015 53:744-752

Three-step channel conformational changes common to DNA packaging motors of bacterial viruses T3, T4, SPP1, and Phi29

Authors: Wang, Shaoying, Ji, Zhouxiang, Yan, Erfu, Haque, Farzin, Guo, Peixuan

Source: Virology. 500:285-291

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100051619065.0x000001&indx=1&recIds=ETOCvdc_100051619065.0x000001

Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression

Authors: Pi, Fengmei, Binzel, Daniel W., Lee, Tae Jin, Li, Zhefeng, Sun, Meiyan, Rychahou, Piotr, Li, Hui, Haque, Farzin, Wang, Shaoying, Croce, Carlo M., Guo, Bin, Evers, B. Mark, Guo, Peixuan

Source: Nature nanotechnology. 13(1):82-89

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130015951.0x000001&indx=1&recIds=ETOCvdc_100130015951.0x000001

Using Planar Phi29 pRNA Three-Way Junction to Control Size and Shape of RNA Nanoparticles for Biodistribution Profiling in Mice

Authors: Haque, Farzin, Xu, Congcong, Jasinski, Daniel L., Li, Hui, Guo, Peixuan

Source: Methods in molecular biology. 1632:359-380

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN612305169&indx=1&recIds=ETOCRN612305169

Stable RNA nanoparticles as potential new generation drugs for cancer therapy

Authors: Shu, Yi, Pi, Fengmei, Sharma, Ashwani, Rajabi, Mehdi, Haque, Farzin, Shu, Dan, Leggas, Markos, Evers, B. Mark, Guo, Peixuan

Source: In Advanced Drug Delivery Reviews February 2014 66:74-89

Solid-state and biological nanopore for real-time sensing of single chemical and sequencing of DNA

Authors: Haque, Farzin, Li, Jinghong, Wu, Hai-Chen, Liang, Xing-Jie, Guo, Peixuan

Source: In Nano Today February 2013 8(1):56-74

Systemic Delivery of Anti-miRNA for Suppression of Triple Negative Breast Cancer Utilizing RNA Nanotechnology

Authors: Shu, Dan, Li, Hui, Shu, Yi, Xiong, Gaofeng, Carson, William E., Haque, Farzin, Xu, Ren, Guo, Peixuan

Source: ACS nano. 9(10):9731-9740

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN603545060&indx=1&recIds=ETOCRN603545060

Delivery of RNA Nanoparticles into Colorectal Cancer Metastases Following Systemic Administration

Authors: Rychahou, Piotr, Haque, Farzin, Shu, Yi, Zaytseva, Yekaterina, Weiss, Heidi L., Lee, Eun Y., Mustain, William, Valentino, Joseph, Guo, Peixuan, Evers, B. Mark

Source: ACS nano. 9(2):1108-1116

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN600429509&indx=1&recIds=ETOCRN600429509

Ultrastable synergistic tetravalent RNA nanoparticles for targeting to cancers

Authors: Haque, Farzin, Shu, Dan, Shu, Yi, Shlyakhtenko, Luda S., Rychahou, Piotr G., Mark Evers, B., Guo, Peixuan

Source: In Nano Today August 2012 7(4):245-257

Role of Channel Lysines and the “Push Through a One-Way Valve” Mechanism of the Viral DNA Packaging Motor

Authors: Fang, Huaming, Jing, Peng, Haque, Farzin, Guo, Peixuan

Source: In Biophysical Journal 4 January 2012 102(1):127-135

Three reversible and controllable discrete steps of channel gating of a viral DNA packaging motor

Authors: Geng, Jia, Fang, Huaming, Haque, Farzin, Zhang, Le, Guo, Peixuan

Source: In Biomaterials 2011 32(32):8234-8242