A recombinant protein vaccine induces protective immunity against SARS-CoV-2 JN.1 and XBB-lineage subvariants

Authors: Jingyun Yang, Weiqi Hong, Huashan Shi, Zhenling Wang, Cai He, Hong Lei, Hong Yan, Aqu Alu, Danyi Ao, Zimin Chen, Yanan Zhou, Hao Yang, Yun Yang, Wenhai Yu, Cong Tang, Junbin Wang, Bai Li, Qing Huang, Hongbo Hu, Wei Cheng, Haohao Dong, Jian Lei, Lu Chen, Xikun Zhou, Li Yang, Wei Wang, Guobo Shen, Jinliang Yang, Zhiwei Zhao, Xiangrong Song, Qiangming Sun, Youchun Wang, Shuaiyao Lu, Jiong Li, Guangwen Lu, Weimin Li, Yuquan Wei, Xiawei Wei

Source: Signal Transduction and Targeted Therapy, Vol 10, Iss 1, Pp 1-15 (2025)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/690b2150733c4ab29cda7334ea12fa3a

Deciphering the molecular basis of lipoprotein recognition and transport by LolCDE

Authors: Wen Qiao, Chongrong Shen, Yujiao Chen, Shenghai Chang, Xin Wang, Lili Yang, Jie Pang, Qinghua Luo, Zhibo Zhang, Yingxin Xiang, Chao Zhao, Guangwen Lu, Bi-Sen Ding, Binwu Ying, Xiaodi Tang, Haohao Dong

Source: Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-12 (2024)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/b66c6b0810f74304bf3894a88112c39c

Intranasal delivery of a subunit protein vaccine provides protective immunity against JN.1 and XBB-lineage variants

Authors: Hong Lei, Weiqi Hong, Jingyun Yang, Cai He, Yanan Zhou, Yu Zhang, Aqu Alu, Jie Shi, Jian Liu, Furong qin, Danyi Ao, Xiya Huang, Zimin Chen, Hao Yang, Yun Yang, Wenhai Yu, Cong Tang, Junbin Wang, Bai Li, Qing Huang, Hongbo Hu, Wei Cheng, Haohao Dong, Jian Lei, Lu Chen, Xikun Zhou, Jiong Li, Li Yang, Zhenling Wang, Wei Wang, Guobo Shen, Jinliang Yang, Zhiwei Zhao, Xiangrong Song, Guangwen Lu, Qiangming Sun, Youchun Wang, Shuaiyao Lu, Xiawei Wei

Source: Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-13 (2024)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/4039a5b9350c462c956fad1e5cfd6111

The combination of rAAV pseudo-lipid nanoparticle and triamcinolone acetonide enables multi-administration to liver

Authors: Chunmei Gan, Mi Leng, Yu Liu, Zhaoyue Zheng, Siwu He, Wen Qiao, Lin Xiao, Yao Xiao, Jingya Ye, Lixing Zhou, Jiao Zhou, Boduan Xiao, Wenxin Zhao, Jiamei Yang, Aohan Wu, Huiyuan Zhang, Hongbo Hu, Xiaobo Cen, Zhiyong Qian, Haohao Dong, C. Alexander Valencia, Lunzhi Dai, Hoi Yee Chow, Lei Zhang, Biao Dong

Source: Molecular Therapy: Methods & Clinical Development, Vol 33, Iss 1, Pp 101399- (2025)

Subject Terms: recombinant adeno-associated virus, lipid nanoparticle, corticosteroid, immunosuppression, multiple systemic administration, Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050124002158; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/e600824c6c1b44acb14b30e69690dab5

Structural insights into the mechanotransducing mechanism of FtsEX in cell division

Authors: Yuejia Chen, Du Guo, Xin Wang, Changbin Zhang, Yatian Chen, Qinghua Luo, Yujiao Chen, Lili Yang, Zhibo Zhang, Tian Hong, Zhengyu Zhang, Haohao Dong, Shenghai Chang, Jianping Hu, Xiaodi Tang

Source: MedComm, Vol 5, Iss 11, Pp n/a-n/a (2024)

Subject Terms: ABC transporter, cell division, EnvC, FtsEX, mechanotransmission, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2688-2663

Access URL: https://doaj.org/article/1217d081d0d04c89b4fa30fb5ecf0160

Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT

Authors: Tian Hong, Qinghua Luo, Haiyun Ma, Xin Wang, Xinqiong Li, Chongrong Shen, Jie Pang, Yan Wang, Yuejia Chen, Changbin Zhang, Zhaoming Su, Haohao Dong, Xiaodi Tang

Source: Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-10 (2024)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/7a1960f67bde4591b7740fc6c6d71d32

XBB.1.16‐RBD‐based trimeric protein vaccine can effectively inhibit XBB.1.16‐included XBB subvariant infection

Authors: Dandan Peng, Cai He, Zimin Chen, Hong Lei, Xiya Huang, Chunjun Ye, Binhan Wang, Ying Hao, Xinyi Du, Shuaiyao Lu, Hongbo Hu, Wei Cheng, Haohao Dong, Jian Lei, Xikun Zhou, Xiangrong Song, Guangwen Lu, Xiawei Wei

Source: MedComm, Vol 5, Iss 9, Pp n/a-n/a (2024)

Subject Terms: heterologous booster, recombinant RBD‐HR protein, XBB.1.16 variant, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2688-2663

Access URL: https://doaj.org/article/c908ba919f4842c19e66f011e8f0b3e0

Structural insights into the activation of the divisome complex FtsWIQLB

Authors: Lili Yang, Yujiao Chen, Shenghai Chang, Chongrong Shen, Xin Wang, Changbin Zhang, Zhibo Zhang, Bi-Sen Ding, Zhaoming Su, Haohao Dong, Xiaodi Tang

Source: Cell Discovery, Vol 10, Iss 1, Pp 1-4 (2024)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2056-5968

Access URL: https://doaj.org/article/ca1549239e954489b63533e1395dc614

Structure and activity of the septal peptidoglycan hydrolysis machinery crucial for bacterial cell division.

Authors: Yatian Chen, Jiayue Gu, Biao Yang, Lili Yang, Jie Pang, Qinghua Luo, Yirong Li, Danyang Li, Zixin Deng, Changjiang Dong, Haohao Dong, Zhengyu Zhang

Source: PLoS Biology, Vol 22, Iss 5, p e3002628 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/fd623835784347278a537b1563275b60

A chimeric adenovirus‐vectored vaccine based on Beta spike and Delta RBD confers a broad‐spectrum neutralization against Omicron‐included SARS‐CoV‐2 variants

Authors: Weiqi Hong, Hong Lei, Dandan Peng, Yuhe Huang, Cai He, Jingyun Yang, Yanan Zhou, Jian Liu, Xiangyu Pan, Haiying Que, Aqu Alu, Li Chen, Jiayuan Ai, Furong Qin, Binhan Wang, Danyi Ao, Zhen Zeng, Ying Hao, Yu Zhang, Xiya Huang, Chunjun Ye, MinYang Fu, Xuemei He, Zhenfei Bi, Xuejiao Han, Min Luo, Hongbo Hu, Wei Cheng, Haohao Dong, Jian Lei, Lu Chen, Xikun Zhou, Wei Wang, Guangwen Lu, Guobo Shen, Li Yang, Jinliang Yang, Jiong Li, Zhenling Wang, Xiangrong Song, Qiangming Sun, Shuaiyao Lu, Youchun Wang, Ping Cheng, Xiawei Wei

Source: MedComm, Vol 5, Iss 5, Pp n/a-n/a (2024)

Subject Terms: adenovirus, broad‐spectrum neutralization, intranasal vaccine, SARS‐CoV‐2, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2688-2663

Access URL: https://doaj.org/article/5f86cf25f441434681a4705fbc53e5ee

Cryo-EM structure of the nucleocapsid-like assembly of respiratory syncytial virus

Authors: Yan Wang, Chong Zhang, Yongbo Luo, Xiaobin Ling, Bingnan Luo, Guowen Jia, Dan Su, Haohao Dong, Zhaoming Su

Source: Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-9 (2023)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/4e9714bad1894559ad41ee35a8a02f35

Crystal structure of vaccinia virus G3/L5 sub-complex reveals a novel fold with extended inter-molecule interactions conserved among orthopoxviruses

Authors: Sheng Lin, Dan Yue, Fanli Yang, Zimin Chen, Bin He, Yu Cao, Haohao Dong, Jian Li, Qi Zhao, Guangwen Lu

Source: Emerging Microbes and Infections, Vol 12, Iss 1 (2023)

Subject Terms: Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/da87056ffd7b4126b89b142bda45dc81

Structural basis of poxvirus A16/G9 binding for sub-complex formation

Authors: Fanli Yang, Sheng Lin, Zimin Chen, Dan Yue, Ming Yang, Bin He, Yu Cao, Haohao Dong, Jian Li, Qi Zhao, Guangwen Lu

Source: Emerging Microbes and Infections, Vol 12, Iss 1 (2023)

Subject Terms: Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/165272f91d524048b424859c6c17b6f2

Development of a bispecific nanobody conjugate broadly neutralizes diverse SARS-CoV-2 variants and structural basis for its broad neutralization

Authors: Jing Yang, Sheng Lin, Zimin Chen, Fanli Yang, Liyan Guo, Lingling Wang, Yanping Duan, Xindan Zhang, Yushan Dai, Keqing Yin, Chongzhang Yu, Xin Yuan, Honglu Sun, Bin He, Yu Cao, Haoyu Ye, Haohao Dong, Xianbo Liu, Bo Chen, Jian Li, Qi Zhao, Guangwen Lu

Source: PLoS Pathogens, Vol 19, Iss 11 (2023)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688893/?tool=EBI; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/2dffef19e8d7440e90a4d29de22eda9e

An engineered 5-helix bundle derived from SARS-CoV-2 S2 pre-binds sarbecoviral spike at both serological- and endosomal-pH to inhibit virus entry

Authors: Xi Lin, Liyan Guo, Sheng Lin, Zimin Chen, Fanli Yang, Jing Yang, Lingling Wang, Ao Wen, Yanping Duan, Xindan Zhang, Yushan Dai, Keqing Yin, Xin Yuan, Chongzhang Yu, Bin He, Yu Cao, Haohao Dong, Jian Li, Qi Zhao, Guangwen Lu

Source: Emerging Microbes and Infections, Vol 11, Iss 1, Pp 1920-1935 (2022)

Subject Terms: Broad-spectrum inhibition, 5-helix bundle (5HB), SARS-CoV-2, structural basis, viral entry, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/014127c84bd1444aa4fae567ebb2f31f

Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.

Authors: Hua Chen, Sheng Lin, Fanli Yang, Zimin Chen, Liyan Guo, Jing Yang, Xi Lin, Lingling Wang, Yanping Duan, Ao Wen, Xindan Zhang, Yushan Dai, Keqing Yin, Xin Yuan, Chongzhang Yu, Yarong He, Bin He, Yu Cao, Haohao Dong, Jian Li, Qi Zhao, Quan Liu, Guangwen Lu

Source: PLoS Pathogens, Vol 19, Iss 10, p e1011694 (2023)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011694&type=printable; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/9a374ab188f74bdbbce0d0cf34472fe8

Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides

Authors: Jinzhu Zhang, Minghai Tang, Yujie Chen, Dan Ke, Jie Zhou, Xinyu Xu, Wenxian Yang, Jianxiong He, Haohao Dong, Yuquan Wei, James H. Naismith, Yi Lin, Xiaofeng Zhu, Wei Cheng

Source: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/3992bcac521a4b928331e2b513baaeab

Dorsal and ventral striatal functional connectivity shifts play a potential role in internet gaming disorder

Authors: Guang-Heng Dong, Haohao Dong, Min Wang, Jialin Zhang, Weiran Zhou, Xiaoxia Du, Marc N. Potenza

Source: Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/2bc6e54c183f41e7a9f1bdc66d07dcff

Uncovering lipopolysaccharide regulation in bacteria via the critical lipid binding tunnel of YciS/YciM

Authors: Lina Yan, Haohao Dong, Huanyu Li, Xingyu Liu, Zixin Deng, Changjiang Dong, Zhengyu Zhang

Source: iScience, Vol 25, Iss 9, Pp 104988- (2022)

Subject Terms: Biological sciences, Molecular biology, Microbiology, Bacteriology, Structural biology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004222012603; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/42cd7dcb8ccd4dc0b758728030b6611e

A Potent Neutralizing Nanobody Targeting the Spike Receptor-Binding Domain of SARS-CoV-2 and the Structural Basis of Its Intimate Binding

Authors: Jing Yang, Sheng Lin, Honglu Sun, Zimin Chen, Fanli Yang, Xi Lin, Liyan Guo, Lingling Wang, Ao Wen, Xindan Zhang, Yushan Dai, Bin He, Yu Cao, Haohao Dong, Xianbo Liu, Bo Chen, Jian Li, Qi Zhao, Guangwen Lu

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: SARS-CoV-2, spike receptor-binding domain, nanobody, neutralization, structural basis, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.820336/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/2e5be194beba46858f6c196f0b40d75b