Multimodal screen identifies noise-regulatory proteins

Authors: García-Blay, Óscar ^{1, 2}, Hu, Xinyu ^{1, 2}, Wassermann, Christin L. ¹, van Bokhoven, Tom ¹, Struijs, Fréderique M.B. ¹, Hansen, Maike M.K. ^{1, 2, 3, ∗}

Source: In Developmental Cell 6 January 2025 60(1):133-151

Co‐action of COP1, SPA and cryptochrome in light signal transduction and photomorphogenesis of the moss Physcomitrium patens

Authors: Kreiss, Melanie, Haas, Fabian B., Hansen, Maike, Rensing, Stefan A., Hoecker, Ute

Source: Plant journal. 114(1):159-175

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182258733.0x000001&indx=1&recIds=ETOCvdc_100182258733.0x000001

'What's (the) Matter?', A Show on Elementary Particle Physics with 28 Demonstration Experiments

Authors: Dreiner, Herbi K., Becker, Max, Borzyszkowski, Mikolaj, Braun, Maxim, Faßbender, Alexander, Hampel, Julia, Hansen, Maike, Hebecker, Dustin, Heepenstrick, Timo, Heinz, Sascha, Hortmanns, Katharina, Jost, Christian, Kortmann, Michael, Kruckow, Matthias U., Leuteritz, Till, Lütz, Claudia, Mahlberg, Philip, Müllers, Johannes, Opferkuch, Toby, Paul, Ewald, Pauli, Peter, Rossbach, Merlin, Schaepe, Steffen, Schiffer, Tobias, Schmidt, Jan F., Schüller-Ruhl, Jana, Schürmann, Christoph, Ubaldi, Lorenzo, Wagner-Carena, Sebastian

Subject Terms: Physics - Popular Physics, High Energy Physics - Experiment, High Energy Physics - Phenomenology, High Energy Physics - Theory, Physics - Physics Education

Access URL: http://arxiv.org/abs/1607.07478

Cytoplasmic Amplification of Transcriptional Noise Generates Substantial Cell-to-Cell Variability

Authors: Hansen, Maike M.K., Desai, Ravi V., Simpson, Michael L., Weinberger, Leor S.

Source: In Cell Systems 24 October 2018 7(4):384-397

A Post-Transcriptional Feedback Mechanism for Noise Suppression and Fate Stabilization

Authors: Hansen, Maike M.K., Wen, Winnie Y., Ingerman, Elena, Razooky, Brandon S., Thompson, Cassandra E., Dar, Roy D., Chin, Charles W., Simpson, Michael L., Weinberger, Leor S.

Source: In Cell 14 June 2018 173(7):1609-1621

ARTseq-FISH reveals position-dependent differences in gene expression of micropatterned mESCs.

Authors: Hu, Xinyu, van Sluijs, Bob, García-Blay, Óscar, Stepanov, Yury, Rietrae, Koen, Huck, Wilhelm T. S., Hansen, Maike M. K.

Source: Nature Communications; 5/9/2024, Vol. 15 Issue 1, p1-17, 17p

Subject Terms: GENE expression, EMBRYONIC stem cells, CHEMICAL labeling, PHOSPHOPROTEINS

HIV Latency: Stochastic across Multiple Scales

Authors: Hansen, Maike M.K., Martin, Benjamin, Weinberger, Leor S.

Source: Cell host & microbe. 26(6):703-705

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100093985075.0x000001&indx=1&recIds=ETOCvdc_100093985075.0x000001

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly.

Authors: Murigneux, Emilie, Softic, Laurent, Aubé, Corentin, Grandi, Carmen, Judith, Delphine, Bruce, Johanna, Le Gall, Morgane, Guillonneau, François, Schmitt, Alain, Parissi, Vincent, Berlioz-Torrent, Clarisse, Meertens, Laurent, Hansen, Maike M. K., Gallois-Montbrun, Sarah

Source: Nature Communications; 1/20/2024, Vol. 15 Issue 1, p1-17, 17p

Subject Terms: PARTICLE analysis, PROTEOMICS, VIRION, SARS-CoV-2, ULTRACENTRIFUGATION

Exploring the role of transcriptional and post‐transcriptional processes in mRNA co‐expression.

Authors: García‐Blay, Óscar, Verhagen, Pieter G. A., Martin, Benjamin, Hansen, Maike M. K.

Source: BioEssays; Dec2023, Vol. 45 Issue 12, p1-15, 15p

Subject Terms: MESSENGER RNA, GENETIC transcription regulation, GENE expression, GENE clusters, GENETIC regulation

Protocol for simultaneous detection of mRNAs and (phospho-)proteins with ARTseq-FISH in mouse embryonic stem cells

Authors: Hu, Xinyu ^{1, 2, 3}, van Sluijs, Bob ¹, García-Blay, Óscar ^{1, 2}, Huck, Wilhelm T.S. ^{1, ∗}, Hansen, Maike M.K. ^{1, 2, 4, ∗∗}

Source: In STAR Protocols 20 December 2024 5(4)

Enhanced transcription rates in membrane-free protocells formed by coacervation of cell lysate

Authors: Sokolova, Ekaterina, Spruijt, Evan, Hansen, Maike M. K., Dubuc, Emilien, Groen, Joost, Chokkalingam, Venkatachalam, Piruska, Aigars, Heus, Hans A., Huck, Wilhelm T. S.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2013 Jul . 110(29), 11692-11697.

Access URL: https://www.jstor.org/stable/42712463

Environmental gradients reveal stress hubs pre-dating plant terrestrialization.

Authors: Dadras, Armin, Fürst-Jansen, Janine M. R., Darienko, Tatyana, Krone, Denis, Scholz, Patricia, Sun, Siqi, Herrfurth, Cornelia, Rieseberg, Tim P., Irisarri, Iker, Steinkamp, Rasmus, Hansen, Maike, Buschmann, Henrik, Valerius, Oliver, Braus, Gerhard H., Hoecker, Ute, Feussner, Ivo, Mutwil, Marek, Ischebeck, Till, de Vries, Sophie, Lorenz, Maike

Source: Nature Plants; Sep2023, Vol. 9 Issue 9, p1419-1438, 20p

Noise Minimization in Cell-Free Gene Expression.

Authors: Bartelds, Mart W., García-Blay, Óscar, Verhagen, Pieter G. A., Wubbolts, Elise J., van Sluijs, Bob, Heus, Hans A., de Greef, Tom F. A., Huck, Wilhelm T. S., Hansen, Maike M. K.

Source: ACS Synthetic Biology; 8/18/2023, Vol. 12 Issue 8, p2217-2225, 9p

Protocol for in vitro transcribing mRNAs with defined poly(A)-tail lengths and visualizing sequential PABP binding

Authors: Grandi, Carmen ^{1, 2, 3}, Emmaneel, Martin ^{1, 2}, Nelissen, Frank H.T. ^{1, 2}, Hansen, Maike M.K. ^{1, 2, 4, ∗}

Source: In STAR Protocols 20 September 2024 5(3)

Post‐Transcriptional Noise Control

Authors: Hansen, Maike M. K., Weinberger, Leor S.

Source: BioEssays. 41(7)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085904867.0x000001&indx=1&recIds=ETOCvdc_100085904867.0x000001

Counting mRNAs: Single-molecule in vitro transcription (smIVT) assay

Authors: Bogatyr, Vadim G., Biebricher, Andreas S., Hansen, Maike M.K., Maas, Roel J.M., Huck, Wilhelm T.S., wuite, Gijs J.L.

Source: In Biophysical Journal 8 February 2024 123(3) Supplement 1:224a-224a

TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV.

Authors: Matkovic, Roy, Morel, Marina, Lanciano, Sophie, Larrous, Pauline, Martin, Benjamin, Bejjani, Fabienne, Vauthier, Virginie, Hansen, Maike M. K., Emiliani, Stéphane, Cristofari, Gael, Gallois-Montbrun, Sarah, Margottin-Goguet, Florence

Source: Nature Communications; 1/10/2022, Vol. 13 Issue 1, p1-17, 17p

Subject Terms: RNA polymerase II, RNA, HIV, PROTEOLYSIS, EPIGENETICS, RNA metabolism

Nonlatching positive feedback enables robust bimodality by decoupling expression noise from the mean.

Authors: Razooky, Brandon S.^1,2,3,4,5, Cao, Youfang^6,7, Hansen, Maike M. K.², Perelson, Alan S.⁶, Simpson, Michael L.^4,5, simpsonml1@ornl.gov, Weinberger, Leor S.^2,8,9,10, leor.weinberger@gladstone.ucsf.edu

Source: PLoS Biology; 10/18/2017, Vol. 15 Issue 10, p1-26, 26p, 2 Diagrams, 3 Graphs

Effectors with Different Gears: Divergence of Ustilago maydis Effector Genes Is Associated with Their Temporal Expression Pattern during Plant Infection.

Authors: Depotter, Jasper R. L., Weiliang Zuo, Hansen, Maike, Boqi Zhang, Mingliang Xu, Doehlemann, Gunther

Source: Journal of Fungi; Jan2021, Vol. 7 Issue 1, p1-14, 14p

Subject Terms: USTILAGO maydis, PHYTOPATHOGENIC microorganisms, IMMUNE system, AMINO acid analysis, CELL proliferation

Protocol for in vitrotranscribing mRNAs with defined poly(A)-tail lengths and visualizing sequential PABP binding

Authors: Grandi, Carmen, Emmaneel, Martin, Nelissen, Frank H.T., Hansen, Maike M.K.

Source: STAR Protocols; September 2024, Vol. 5 Issue: 3