Pembrolizumab in microsatellite instability-high/mismatch repair deficient (MSI-H/dMMR) and non–MSI-H/non–dMMR advanced endometrial cancer: Phase 2 KEYNOTE-158 study results

Authors: O'Malley, David M. ^{a, ⁎}, Bariani, Giovani M. ^b, Cassier, Philippe A. ^c, Marabelle, Aurelien ^d, Hansen, Aaron R. ^e, Acosta, Ana De Jesus ^f, Miller, Wilson H., Jr ^g, Safra, Tamar ^h, Italiano, Antoine ^{i, j}, Mileshkin, Linda ^k, Yao, Lili ^l, Gozman, Alexander ^l, Jin, Fan ^l, Maio, Michele ^m

Source: In Gynecologic Oncology February 2025 193:130-135

Advancing patient-centric care: integrating patient reported outcomes for tolerability assessment in early phase clinical trials – insights from an expert virtual roundtable

Authors: Yap, Christina, Lee Aiyegbusi, Olalekan, Alger, Emily, Basch, Ethan, Bell, Jill, Bhatnagar, Vishal, Cella, David, Collis, Philip, Dueck, Amylou C., Gilbert, Alexandra, Gnanasakthy, Ari, Greystoke, Alastair, Hansen, Aaron R., Kamudoni, Paul, Kholmanskikh, Olga, King-Kallimanis, Bellinda L., Krumholz, Harlan, Minchom, Anna, O'Connor, Daniel, Petrie, Joan, Piccinin, Claire, Rantell, Khadija Rerhou, Rauz, Saaeha, Retzer, Ameeta, Rizk, Steven, Wagner, Lynne, Sasseville, Maxime, Seymour, Lesley K., Weber, Harald A., Wilson, Roger, Calvert, Melanie, Peipert, John Devin

Source: In eClinicalMedicine October 2024 76

A Phase II, Open-Label, Randomized Trial of Durvalumab With Olaparib or Cediranib in Patients With Mismatch Repair—Proficient Colorectal or Pancreatic Cancer

Authors: Hernando-Calvo, Alberto, Han, Ming, Ayodele, Olubukola, Wang, Ben X., Bruce, Jeffrey P., Abbas-Aghababazadeh, Farnoosh, Vila-Casadesús, Maria, Sanz-Garcia, Enrique, Yang, S.Y. Cindy, Berman, Hal K., Vivancos, Ana, Lam, Bernard, Lungu, Ilinca, Salawu, Abdulazeez, Stayner, Lee-Anne, Haibe-Kains, Benjamin, Bedard, Philippe L., Avery, Lisa, Razak, Albiruni R.A., Pugh, Trevor J., Spreafico, Anna, Siu, Lillian L., Hansen, Aaron R.

Source: In Clinical Colorectal Cancer September 2024 23(3):272-284

Impact of teratoma on survival probabilities of patients with metastatic non-seminomatous germ cell cancer: Results from the IGCCCG Update Consortium

Authors: Bührer, Emanuel, D'Haese, David, Daugaard, Gedske, de Wit, Ronald, Albany, Costantine, Tryakin, Alexey, Fizazi, Karim, Stahl, Olof, Gietema, Jourik A., De Giorgi, Ugo, Cafferty, Fay H., Hansen, Aaron R., Tandstad, Torgrim, Huddart, Robert A., Necchi, Andrea, Sweeney, Christopher J., Garcia-Del-Muro, Xavier, Heng, Daniel Y.C., Lorch, Anja, Chovanec, Michal, Winquist, Eric, Grimison, Peter, Feldman, Darren R., Terbuch, Angelika, Hentrich, Marcus, Bokemeyer, Carsten, Negaard, Helene, Fankhauser, Christian, Shamash, Jonathan, Vaughn, David J., Sternberg, Cora N., Heidenreich, Axel, Collette, Laurence, Gillessen, Silke, Beyer, Jörg

Source: In European Journal of Cancer May 2024 202

Circulating tumour DNA kinetics in recurrent/metastatic head and neck squamous cell cancer patients

Authors: Taylor, Kirsty, Zou, Jinfeng, Magalhaes, Marcos, Oliva, Marc, Spreafico, Anna, Hansen, Aaron R., McDade, Simon S., Coyle, Vicky M., Lawler, Mark, Elimova, Elena, Bratman, Scott V., Siu, Lillian L.

Source: In European Journal of Cancer July 2023 188:29-38

Phase 1 Study of Safety and Preliminary Clinical Activity of JNJ-63898081, a PSMA and CD3 Bispecific Antibody, for Metastatic Castration-Resistant Prostate Cancer

Authors: Lim, Emerson A., Schweizer, Michael T., Chi, Kim N., Aggarwal, Rahul, Agarwal, Neeraj, Gulley, James, Attiyeh, Edward, Greger, James, Wu, Shujian, Jaiprasart, Pharavee, Loffredo, John, Bandyopadhyay, Nibedita, Xie, Hong, Hansen, Aaron R.

Source: In Clinical Genitourinary Cancer June 2023 21(3):366-375

Feasibility and acceptability of remote symptom monitoring (RSM) in older adults during treatment for metastatic prostate cancer

Authors: Feng, Gregory, Parthipan, Milothy, Breunis, Henriette, Puts, Martine, Emmenegger, Urban, Timilshina, Narhari, Hansen, Aaron R., Finelli, Antonio, Krzyzanowska, Monika K., Matthew, Andrew, Clarke, Hance, Mina, Daniel Santa, Soto-Perez-de-Celis, Enrique, Tomlinson, George, Alibhai, Shabbir M.H.

Source: In Journal of Geriatric Oncology April 2023 14(3)

The role of frailty in modifying physical function and quality of life over time in older men with metastatic castration-resistant prostate cancer

Authors: Kim, Valerie S., Yang, Helen, Timilshina, Narhari, Breunis, Henriette, Emmenegger, Urban, Gregg, Richard, Hansen, Aaron R., Tomlinson, George, Alibhai, Shabbir M.H.

Source: In Journal of Geriatric Oncology March 2023 14(2)

Evaluation of pembrolizumab monotherapy in patients with previously treated advanced salivary gland carcinoma in the phase 2 KEYNOTE-158 study

Authors: Even, Caroline, Delord, Jean-Pierre, Price, Katharine A., Nakagawa, Kazuhiko, Oh, Do-Youn, Burge, Matthew, Chung, Hyun C., Doi, Toshihiko, Fakih, Marwan, Takahashi, Shunji, Yao, Lili, Jin, Fan, Norwood, Kevin, Hansen, Aaron R.

Source: In European Journal of Cancer August 2022 171:259-268

Outcomes of Radiation Therapy Plus Immunotherapy in Metastatic Renal Cell Carcinoma: Results From the Canadian Kidney Cancer Information System

Authors: Nguyen, Eric K., Lalani, Aly Khan A., Ghosh, Sunita, Basappa, Naveen S., Kapoor, Anil, Hansen, Aaron R., Kollmannsberger, Christian, Heng, Daniel, Wood, Lori A., Castonguay, Vincent, Soulières, Denis, Winquist, Eric, Canil, Christina, Graham, Jeffrey, Bjarnason, Georg A., Breau, Rodney H., Pouliot, Frédéric, Swaminath, Anand

Source: In Advances in Radiation Oncology July-August 2022 7(4)

Comprehensive genomic profiling of treatment resistant metastatic castrate sensitive prostate cancer reveals high frequency of potential therapeutic targets

Authors: Kappel, Coralea, Jiang, Di Maria, Wong, Bryan, Zhang, Tong, Selvarajah, Shamini, Warner, Evan, Hansen, Aaron R., Fallah-Rad, Nazanin, Sacher, Adrian G., Stockley, Tracy L., Bedard, Philippe L., Sridhar, Srikala S.

Source: In Clinical Genitourinary Cancer June 2022 20(3):278-284

Utilization and Safety of Ipilimumab Plus Nivolumab in a Real-World Cohort of Metastatic Renal Cell Carcinoma Patients

Authors: Thana, Myuran, Basappa, Naveen S., Ghosh, Sunita, Kollmannsberger, Christian K., Heng, Daniel Y.C., Hansen, Aaron R., Graham, Jeffery, Soulières, Denis, Reaume, Martin Neil, Lalani, Aly-Khan A., Castonguay, Vincent, Bjarnason, Georg A., Patenaude, François, Breau, Rodney H., Pouliot, Frédéric, Kapoor, Anil, Wood, Lori A.

Source: In Clinical Genitourinary Cancer June 2022 20(3):210-218

Inter-rater concordance and operating definitions of radiologic nodal feature assessment in human papillomavirus-positive oropharyngeal carcinoma

Authors: Chin, Olivia, Alshafai, Laila, O'Sullivan, Brian, Su, Jie, Hope, Andrew, Bartlett, Eric, Hansen, Aaron R., Waldron, John, Chepeha, Douglas, Xu, Wei, Huang, Shao Hui, Yu, Eugene

Source: In Oral Oncology February 2022 125

Active Surveillance in Metastatic Renal Cell Carcinoma: Results From the Canadian Kidney Cancer Information System

Authors: Kushnir, Igal, Basappa, Naveen S., Ghosh, Sunita, Lalani, Aly-Khan A., Hansen, Aaron R., Wood, Lori, Kollmannsberger, Christian K., Heng, Daniel Y.C., Bjarnason, Georg A., Soulières, Denis, Dawe, David E., Tanguay, Simon, Breau, Rodney H., Pouliot, Frédéric, Kapoor, Anil, Graham, Jeffrey, Reaume, M. Neil

Source: In Clinical Genitourinary Cancer December 2021 19(6):521-530

Phase II Trial of Trametinib and Panitumumab in RAS/RAF Wild Type Metastatic Colorectal Cancer

Authors: Alshammari, Kanan, Aung, Kyaw L., Zhang, Tong, Razak, Albiruni R.A., Serra, Stefano, Stockley, Tracy, Wang, Lisa, Nguyen, Jessica, Spreafico, Anna, Hansen, Aaron R., Zwir, Dave, Siu, Lillian L., Bedard, Philippe L.

Source: In Clinical Colorectal Cancer December 2021 20(4):334-341

Outcome and treatment toxicity in east-indian versus white-canadian patients with oral cavity cancer following postoperative (chemo-)radiotherapy delivered under similar multidisciplinary care: A propensity-matched cohort study

Authors: Gudi, Shivakumar, O'Sullivan, Brian, Hosni, Ali, Su, Jie, Hope, Andrew, Ringash, Jolie, Hueniken, Katrina, Liu, Geoffrey, Tong, Li, Goldstein, David, de Almeida, John, Hansen, Aaron R., Bratman, Scott V., Cho, John, Giuliani, Meredith, Hahn, Ezra, Kim, John, Xu, Wei, Waldron, John, Huang, Shao Hui

Source: In Oral Oncology September 2021 120

Clinical Effectiveness of Second-line Sunitinib Following Immuno-oncology Therapy in Patients with Metastatic Renal Cell Carcinoma: A Real-world Study

Authors: Wells, J. Connor, Dudani, Shaan, Gan, Chun Loo, Stukalin, Igor, Azad, Arun A., Liow, Elizabeth, Donskov, Frede, Yuasa, Takeshi, Pal, Sumanta K., De Velasco, Guillermo, Hansen, Aaron R., Beuselinck, Benoit, Kollmannsberger, Christian K., Powles, Thomas, McGregor, Bradley A., Duh, Mei S., Huynh, Lynn, Heng, Daniel Y.C.

Source: In Clinical Genitourinary Cancer August 2021 19(4):354-361

Efficacy of immune-checkpoint inhibitors (ICI) in the treatment of older adults with metastatic renal cell carcinoma (mRCC) – an International mRCC Database Consortium (IMDC) analysis

Authors: Araujo, Daniel V., Wells, J. Connor, Hansen, Aaron R., Dizman, Nazli, Pal, Sumanta K., Beuselinck, Benoit, Donskov, Frede, Gan, Chun L., Yan, Flora, Tran, Ben, Kollmannsberger, Christian K., de Velasco, Guillermo, Yuasa, Takeshi, Reaume, M. Neil, Ernst, D. Scott, Powles, Thomas, Bjarnason, Georg A., Choueiri, Toni K., Heng, Daniel Y.C., Dudani, Shaan

Source: In Journal of Geriatric Oncology June 2021 12(5):820-826

Prognostic value of clinical and radiologic extranodal extension and their role in the 8th edition TNM cN classification for HPV-negative oropharyngeal carcinoma

Authors: Pilar, Avinash, Yu, Eugene, Su, Jie, O'Sullivan, Brian, Bartlett, Eric, Waldron, John N., Ringash, Jolie, Spreafico, Anna, Hansen, Aaron R., de Almeida, John, Bayley, Andrew, Bratman, Scott V., Cho, John, Giuliani, Meredith, Hope, Andrew, Hosni, Ali, Kim, John, Tong, Li, Xu, Wei, Huang, Shao Hui

Source: In Oral Oncology March 2021 114

Pathologic concordance of resected metastatic nonseminomatous germ cell tumors in the chest

Authors: Donahoe, Laura L., Nason, Gregory J., Bedard, Philippe L., Hansen, Aaron R., Jewett, Michael A.S., Hamilton, Robert J., de Perrot, Marc

Source: In The Journal of Thoracic and Cardiovascular Surgery March 2021 161(3):856-868