Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation

Authors: Schwerbel, Kristin, Kamitz, Anne, Krahmer, Natalie, Hallahan, Nicole, Jähnert, Markus, Gottmann, Pascal, Lebek, Sandra, Schallschmidt, Tanja, Arends, Danny, Schumacher, Fabian, Kleuser, Burkhard, Haltenhof, Tom, Heyd, Florian, Gancheva, Sofiya, Broman, Karl W., Roden, Michael, Joost, Hans-Georg, Chadt, Alexandra, Al-Hasani, Hadi, Vogel, Heike, Jonas, Wenke, Schürmann, Annette

Source: In Journal of Hepatology October 2020 73(4):771-782

Capillary contact points determine beta cell polarity, control secretion and are disrupted in the db/db mouse model of diabetes.

Authors: Jevon, Dillon, Cottle, Louise, Hallahan, Nicole, Harwood, Richard, Samra, Jaswinder S., Gill, Anthony J., Loudovaris, Thomas, Thomas, Helen E., Thorn, Peter

Source: Diabetologia; Aug2024, Vol. 67 Issue 8, p1683-1697, 15p

A computational biology approach of a genome-wide screen connected miRNAs to obesity and type 2 diabetes

Authors: Gottmann, Pascal, Ouni, Meriem, Saussenthaler, Sophie, Roos, Julian, Stirm, Laura, Jähnert, Markus, Kamitz, Anne, Hallahan, Nicole, Jonas, Wenke, Fritsche, Andreas, Häring, Hans-Ulrich, Staiger, Harald, Blüher, Matthias, Fischer-Posovszky, Pamela, Vogel, Heike, Schürmann, Annette

Source: In Molecular Metabolism May 2018 11:145-159

Abstract 1656: Presynaptic scaffold protein, liprin, regulates glucose stimulated insulin secretion and the spatial organisation of exocytosis in pancreatic β-cells

Authors: Deng, Kylie, Hallahan, Nicole, Sun, Kitty, Thorn, Peter

Source: In Journal of Biological Chemistry 2023 299(3) Supplement

Two Novel Candidate Genes for Insulin Secretion Identified by Comparative Genomics of Multiple Backcross Mouse Populations.

Authors: Schallschmidt, Tanja^1,2, Lebek, Sandra^1,2, Altenhofen, Delsi^1,2, Damen, Mareike^1,2, Schulte, Yvonne^1,2, Knebel, Birgit^1,2, Stermann, Torben^1,2, Chadt, Alexandra^1,2, Al-Hasani, Hadi^1,2, Kamitz, Anne^2,3, Hallahan, Nicole^2,3, Jähnert, Markus^2,3, Vogel, Heike^2,3, Schürmann, Annette^2,3, Herwig, Ralf⁴, Rasche, Axel⁴

Source: Genetics; Dec2018, Vol. 210 Issue 4, p1527-1542, 17p

Metabolic defects induced by high-fat feeding in mice are rapidly reversed by a low-fat diet

Authors: Hallahan Nicole L, Leslie Simon J, Turner Nigel, Cooney Gregory J

Source: BMC Proceedings, Vol 6, Iss Suppl 3, p P49 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1753-6561

Access URL: https://doaj.org/article/54df2f54d3f64a1aa4293521b5b9a4e2

Local activation of focal adhesion kinase orchestrates the positioning of presynaptic scaffold proteins and Ca²⁺ signalling to control glucose- dependent insulin secretion.

Authors: Jevon, Dillon, Deng, Kylie, Hallahan, Nicole, Kumar, Krish, Tong, Jason, Gan, Wan Jun, Tran, Clara, Bilek, Marcela, Thorn, Peter

Source: eLife; 5/23/2022, p1-25, 25p

Bioactivation of Encapsulation Membranes Reduces Fibrosis and Enhances Cell Survival.

Authors: Tan, Richard P., Hallahan, Nicole, Kosobrodova, Elena, Michael, Praveesuda L., Wei, Fei, Santos, Miguel, Lam, Yuen Ting, Chan, Alex H. P., Xiao, Yin, Bilek, Marcela M. M., Thorn, Peter, Wise, Steven G.

Source: ACS Applied Materials & Interfaces; 12/23/2020, Vol. 12 Issue 51, p56908-56923, 16p

Identification of Novel Potential Type 2 Diabetes Genes Mediating β-Cell Loss and Hyperglycemia Using Positional Cloning.

Authors: Aga, Heja, Hallahan, Nicole, Gottmann, Pascal, Jaehnert, Markus, Osburg, Sophie, Schulze, Gunnar, Kamitz, Anne, Arends, Danny, Brockmann, Gudrun, Schallschmidt, Tanja, Lebek, Sandra, Chadt, Alexandra, Al-Hasani, Hadi, Joost, Hans-Georg, Schürmann, Annette, Vogel, Heike

Source: Frontiers in Genetics; 9/30/2020, Vol. 11, pN.PAG-N.PAG, 11p

Subject Terms: TYPE 2 diabetes, ISLANDS of Langerhans, BLOOD sugar, GLYCEMIC control, METABOLIC disorders, MOLECULAR cloning

Geographic Terms: NEW Zealand

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Plasma Surface Engineering to Biofunctionalise Polymers for β-Cell Adhesion.

Authors: Tran, Clara¹, clara.tran@sydney.edu.aukosobrodova@fastmail.com.au, Hallahan, Nicole², nic.hallahan@gmail.com, Kosobrodova, Elena¹, marcela.bilek@sydney.edu.au, Tong, Jason², jason.tong@rdm.ox.ac.uk, Thorn, Peter², p.thorn@sydney.edu.au, Bilek, Marcela¹

Source: Coatings (2079-6412); Sep2021, Vol. 11 Issue 9, p1085-1085, 1p

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High Passage MIN6 Cells Have Impaired Insulin Secretion with Impaired Glucose and Lipid Oxidation.

Authors: Kim Cheng, Delghingaro-Augusto, Viviane, Nolan, Christopher J., Turner, Nigel, Hallahan, Nicole, Andrikopoulos, Sofianos, Gunton, Jenny E.

Source: PLoS ONE; Jul2012, Vol. 7 Issue 7, p1-12, 12p

Subject Terms: TYPE 2 diabetes, INSULIN, GLUCOSE metabolism, HOMEOSTASIS, LIPID metabolism

Enhanced responsiveness to T-cell help causes loss of B-lymphocyte tolerance to a β-cell neo-self-antigen in type 1 diabetes prone NOD mice.

Authors: Cox, Selwyn Lewis, Stolp, Jessica, Hallahan, Nicole L., Counotte, Jacqueline, Zhang, Wenyu, Serreze, David V., Basten, Antony, Silveira, Pablo A.

Source: European Journal of Immunology; Dec2010, Vol. 40 Issue 12, p3413-3425, 13p

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Metabolic defects induced by high-fat feeding in mice are rapidly reversed by a low-fat diet.

Authors: Turner, Nigel, Leslie, Simon J., Hallahan, Nicole L., Cooney, Gregory J.

Source: BMC Proceedings; 2012, Vol. 6 Issue Suppl 3, p1-1, 1p

Subject Terms: METABOLISM, LOW-fat diet