Integrative Transcriptome‐Wide Association Study With Expression Quantitative Trait Loci Colocalization Identifies a Causal VAMP8 Variant for Nasopharyngeal Carcinoma Susceptibility

Authors: Yan Liang, Xiang‐Yu Xiong, Guo‐Wang Lin, Xiaomeng Bai, Fugui Li, Josephine Mun‐Yee Ko, Yun‐He Zhou, An‐Yi Xu, Shu‐Qiang Liu, Shuai He, Pan‐Pan Wei, Qiu‐Yan Chen, Lin‐Quan Tang, Vivien Ya‐Fan Wang, Hai‐Qiang Mai, Chun‐Ling Luo, Yanni Zeng, Maria Li Lung, Mingfang Ji, Jin‐Xin Bei

Source: Advanced Science, Vol 12, Iss 11, Pp n/a-n/a (2025)

Subject Terms: expression quantitative trait loci (eQTL), genome‐wide association study (GWAS), nasopharyngeal carcinoma (NPC), transcriptome‐wide association study (TWAS), vesicle‐associated membrane protein 8 (VAMP8), Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/5153cb7d6a664923adbb10e529ad3ccf

Comparison of long-term quality of life and their predictors in survivors between paediatric and adult nasopharyngeal carcinoma in the intensity-modulated radiotherapy era

Authors: Jing Jin, Shan-Shan Guo, Li-Ting Liu, Dong-Xiang Wen, Rong-Ping Liu, Jie-Yi Lin, Si-Qi Liu, Xue-Song Sun, Yu-Jing Liang, Lin-Quan Tang, Hai-Qiang Mai, Qiu-Yan Chen

Source: BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)

Subject Terms: Nasopharyngeal carcinoma (NPC), Long-term quality of life, Paediatric NPC, Adult NPC, Cancer survivors, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/592b2308aec84c75b5b8bac7596abdf6

Single-cell and spatial transcriptome analyses reveal tertiary lymphoid structures linked to tumour progression and immunotherapy response in nasopharyngeal carcinoma

Authors: Yang Liu, Shuang-Yan Ye, Shuai He, Dong-Mei Chi, Xiu-Zhi Wang, Yue-Feng Wen, Dong Ma, Run-Cong Nie, Pu Xiang, You Zhou, Zhao-Hui Ruan, Rou-Jun Peng, Chun-Ling Luo, Pan-Pan Wei, Guo-Wang Lin, Jian Zheng, Qian Cui, Mu-Yan Cai, Jing-Ping Yun, Junchao Dong, Hai-Qiang Mai, Xiaojun Xia, Jin-Xin Bei

Source: Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f9f5d4a7bf504b5fa4c009861bafad39

Joint modeling of longitudinal health-related quality of life during concurrent chemoradiotherapy period and long-term survival among patients with advanced nasopharyngeal carcinoma

Authors: Ji-Bin Li, Shan-Shan Guo, Ting Liu, Zhuo-Chen Lin, Wei-Jie Gong, Lin-Quan Tang, Ling Guo, Hao-Yuan Mo, Hai-Qiang Mai, Qiu-Yan Chen

Source: Radiation Oncology, Vol 19, Iss 1, Pp 1-7 (2024)

Subject Terms: Nasopharyngeal carcinoma, Quality of life, Joint model, Survival, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1748-717X

Access URL: https://doaj.org/article/ee37ef6e8736468db2ceeb2e3bd5d7cc

Prevalence of mental disorders and their associations with age at diagnosis and time since diagnosis of nasopharyngeal cancer

Authors: Wen-Xuan Wang, Yi-Shan Wu, Li-Ping Qi, Anise M. S. Wu, Ying-Ying Zhu, Wei-Jie Gong, Shan-Shan Guo, Yi-Jun Hua, Dong-Hua Luo, Qiu-Yan Chen, Yan-Qun Xiang, Jin-Xin Zhang, Hai-Qiang Mai, Ji-Bin Li

Source: Frontiers in Public Health, Vol 12 (2024)

Subject Terms: nasopharyngeal carcinoma, depression, anxiety, sleep disorders, age at diagnosis, time since diagnosis, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpubh.2024.1469001/full; https://doaj.org/toc/2296-2565

Access URL: https://doaj.org/article/4d2e8df68be346ffa76efcdaf1d8b714

Individualised cumulative cisplatin dose for locoregionally advanced nasopharyngeal carcinoma patients based on induction chemotherapy response and tumour volume

Authors: Jie-Yi Lin, Zi-Jian Lu, Su-Chen Li, Dong-Hua Luo, Ting Liu, Wan-Ru Zhang, Zhen-Chong Yang, Hao-Yuan Mo, Hai-Qiang Mai, Sai-Lan Liu

Source: Therapeutic Advances in Medical Oncology, Vol 16 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1758-8359

Access URL: https://doaj.org/article/341f6e78c58a42d4aa164f05b21422ea

Radiomic signatures reveal multiscale intratumor heterogeneity associated with tissue tolerance and survival in re-irradiated nasopharyngeal carcinoma: a multicenter study

Authors: Ting Liu, Di Dong, Xun Zhao, Xiao-Min Ou, Jun-Lin Yi, Jian Guan, Ye Zhang, Lv Xiao-Fei, Chuan-Miao Xie, Dong-Hua Luo, Rui Sun, Qiu-Yan Chen, Lv Xing, Shan-Shan Guo, Li-Ting Liu, Da-Feng Lin, Yan-Zhou Chen, Jie-Yi Lin, Mei-Juan Luo, Wen-Bin Yan, Mei-Lin He, Meng-Yuan Mao, Man-Yi Zhu, Wen-Hui Chen, Bo-Wen Shen, Shi-Qian Wang, Hai-Lin Li, Lian-Zhen Zhong, Chao-Su Hu, De-Hua Wu, Hai-Qiang Mai, Jie Tian, Lin-Quan Tang

Source: BMC Medicine, Vol 21, Iss 1, Pp 1-13 (2023)

Subject Terms: Recurrent nasopharyngeal carcinoma, Re-radiotherapy, Nasopharyngeal necrosis, Radiomics, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/2857f5bbbf144de9b35a90bda0ec9864

Enhancer remodeling activates NOTCH3 signaling to confer chemoresistance in advanced nasopharyngeal carcinoma

Authors: Lizhen Liu, Peng Deng, Sailan Liu, Jing Han Hong, Rong Xiao, Peiyong Guan, Yali Wang, Peili Wang, Jiuping Gao, Jinghong Chen, Yichen Sun, Jianfeng Chen, Hai-Qiang Mai, Jing Tan

Source: Cell Death and Disease, Vol 14, Iss 8, Pp 1-12 (2023)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/1bdffcc862c14d5fbf6c15dd5b641646

Camrelizumab combined with apatinib in patients with first-line platinum-resistant or PD-1 inhibitor resistant recurrent/metastatic nasopharyngeal carcinoma: a single-arm, phase 2 trial

Authors: Li Yuan, Guo-Dong Jia, Xiao-Fei Lv, Si-Yi Xie, Shan-Shan Guo, Da-Feng Lin, Li-Ting Liu, Dong-Hua Luo, Yi-Fu Li, Shen-Wen Deng, Ling Guo, Mu-Sheng Zeng, Xiu-Yu Cai, Sai-Lan Liu, Xue-Song Sun, Xiao-Yun Li, Su-Chen Li, Qiu-Yan Chen, Lin-Quan Tang, Hai-Qiang Mai

Source: Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/27667fc2633a47359b998b866e9c4201

The efficacy and safety of apatinib plus capecitabine in platinum-refractory metastatic and/or recurrent nasopharyngeal carcinoma: a prospective, phase II trial

Authors: Lin-Quan Tang, Xiao-Yun Li, Zhi-Ming Li, Zhi-Gang Liu, Miao-Zhen Lin, Huan Zhou, Qi-Wen Yu, Jian Zhou, Chong Zhao, Ze-Bin Chen, Xi-Cheng Wang, Jia-Yu Peng, Qiu-Yan Chen, Wen-Feng Fang, Yun-Peng Yang, Bei Zhang, Liang-Ping Xia, Pi-Li Hu, Wei-Han Hu, Yi-Jie Li, Hai-Qiang Mai, Xiu-Yu Cai

Source: BMC Medicine, Vol 21, Iss 1, Pp 1-12 (2023)

Subject Terms: Nasopharyngeal carcinoma, Tyrosine kinase inhibitor, Apatinib, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/d39243ce9eed47f6b32e467b391849f8

A deep learning-based semiautomated workflow for triaging follow-up MR scans in treated nasopharyngeal carcinoma

Authors: Ying-Ying Huang, Yi-Shu Deng, Yang Liu, Meng-Yun Qiang, Wen-Ze Qiu, Wei-Xiong Xia, Bing-Zhong Jing, Chen-Yang Feng, Hao-Hua Chen, Xun Cao, Jia-Yu Zhou, Hao-Yang Huang, Ze-Jiang Zhan, Ying Deng, Lin-Quan Tang, Hai-Qiang Mai, Ying Sun, Chuan-Miao Xie, Xiang Guo, Liang-Ru Ke, Xing Lv, Chao-Feng Li

Source: iScience, Vol 26, Iss 12, Pp 108347- (2023)

Subject Terms: Health technology, Applied computing, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004223024240; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/b4270ef9ccac4c828f68fe93491a5b13

Paclitaxel liposome, cisplatin and 5-fluorouracil-based induction chemotherapy followed by de-escalated intensity-modulated radiotherapy with concurrent cisplatin in stage IVA–IVB childhood nasopharyngeal carcinoma in endemic area: a phase II, single-arm trialResearch in context

Authors: Dong-Hua Luo, Xiao-Yun Li, Shan-Shan Guo, Wan-Ping Guo, Li-Ting Liu, Hao-Yuan Mo, Ling Guo, Xiao-Fei Lv, Li-Zhi Liu, Ji-Bin Li, Qing Liu, Pan Wang, Xue-Song Sun, Sai-Lan Liu, Qiu-Yan Chen, Lin-Quan Tang, Hai-Qiang Mai

Source: The Lancet Regional Health. Western Pacific, Vol 40, Iss , Pp 100895- (2023)

Subject Terms: Nasopharyngeal carcinoma, Children and adolescents, Chemoradiotherapy, Induction chemotherapy, Survival, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666606523002134; https://doaj.org/toc/2666-6065

Access URL: https://doaj.org/article/fb7b6b29c54f415da4ab3124c69dc6d0

Clinical characteristics and prognostic factors affecting survival after radical radiotherapy for early and late post-treatment metastatic nasopharyngeal carcinoma

Authors: Guo-Dong Jia, Xue-Song Sun, Xiao-Yun Li, Sai-Lan Liu, Jin-Hao Yang, Qiu-Yan Chen, Li Yuan, Hai-Qiang Mai

Source: BMC Cancer, Vol 23, Iss 1, Pp 1-9 (2023)

Subject Terms: Nasopharyngeal carcinoma, Prognosis, Early metastatic, Late metastatic, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/1410bcd9097d4f8c8a048374317af5f4

Identifying optimal candidates for postoperative adjuvant therapy among regional persistent/recurrent nasopharyngeal carcinoma patients after neck dissection

Authors: Sai-Lan Liu, Xiao-Yun Li, Xue-Song Sun, Jing-Yun Peng, Chao Lin, Jin-Jie Yan, Qiu-Yan Chen, Lin-Quan Tang, Shan-Shan Guo, Ling Guo, Li-Ting Liu, Hai-Qiang Mai

Source: BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)

Subject Terms: Regional recurrent nasopharyngeal carcinoma, Neck dissection, Postoperative adjuvant therapy, Plasma Epstein–Barr virus, Prognosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/8526add604294940b4931849109b754b

Prognostic significance of AKR1C4 and the advantage of combining EBV DNA to stratify patients at high risk of locoregional recurrence of nasopharyngeal carcinoma

Authors: Shan-Shan Guo, Yan-Zhou Chen, Li-Ting Liu, Rong-Ping Liu, Yu-Jing Liang, Dong-Xiang Wen, Jing Jin, Lin-Quan Tang, Hai-Qiang Mai, Qiu-Yan Chen

Source: BMC Cancer, Vol 22, Iss 1, Pp 1-14 (2022)

Subject Terms: AKR1C4, EBV DNA, Recurrence, Nomogram, Nasopharyngeal carcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/47428624bcb44e6babfc0e3a1c32c52f

Meta-analysis of chemotherapy in nasopharynx carcinoma (MAC-NPC): An update on 26 trials and 7080 patients

Authors: Pierre Blanchard, Anne W.M. Lee, Alexandra Carmel, Ng Wai Tong, Jun Ma, Anthony T.C. Chan, Ruey Long Hong, Ming-Yuan Chen, Lei Chen, Wen-Fei Li, Pei-Yu Huang, Dora L.W. Kwong, Sharon S.X. Poh, Roger Ngan, Hai-Qiang Mai, Camille Ollivier, George Fountzilas, Li Zhang, Jean Bourhis, Anne Aupérin, Benjamin Lacas, Jean-Pierre Pignon, Ellen Benhamou, Somvilai Chakrabandhu, Anthony TC Chan, Qiu-Yan Chen, Yong Chen, Richard J Chappell, Horace Choi, Daniel TT Chua, Melvin Lee Kiang Chua, Julian Higgins, Ming-Huang Hong, Ruey-Long Hong, Edwin Pun Hui, C.F. Hsiao, Michael Kam, Georgia Angeliki Koliou, Dora LW Kwong, Shu-Chuan Lai, Ka On Lam, Michael L LeBlanc, Anne WM Lee, Ho Fun Victor Lee, Wen Fei Li, Brigette Ma, Frankie Mo, James Moon, Wai Tong Ng, Brian O'Sullivan, Claire Petit, Jean Pierre Pignon, Sharon X. Poh, Gerta Rücker, Jonathan Sham, Yoke Lim Soong, Ying Sun, Terence Tan, Lin-Quan Tang, Yuk Tung, Joseph Wee, Xuang Wu, Tingting Xu, Yuan Zhang, Guopei Zhu

Source: Clinical and Translational Radiation Oncology, Vol 32, Iss , Pp 59-68 (2022)

Subject Terms: Individual patient data, Meta-analysis, Randomized trials, Chemotherapy, Nasopharynx carcinoma, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405630821000987; https://doaj.org/toc/2405-6308

Access URL: https://doaj.org/article/d434522ac81e4f6b939f0c3692a98f78

Percent change in apparent diffusion coefficient and plasma EBV DNA after induction chemotherapy identifies distinct prognostic response phenotypes in advanced nasopharyngeal carcinoma

Authors: Li-Ting Liu, Shan-Shan Guo, Hui Li, Chao Lin, Rui Sun, Qiu-Yan Chen, Yu-Jing Liang, Qing-Nan Tang, Xue-Song Sun, Lin-Quan Tang, Chuan-Miao Xie, Hai-Qiang Mai

Source: BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)

Subject Terms: Nasopharyngeal carcinoma, Apparent diffusion coefficient, EBV DNA, Response phenotypes, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/9363cd81165144ca9255c9996b7d1f32

The Chinese Society of Clinical Oncology (CSCO) clinical guidelines for the diagnosis and treatment of nasopharyngeal carcinoma

Authors: Ling‐Long Tang, Yu‐Pei Chen, Chuan‐Ben Chen, Ming‐Yuan Chen, Nian‐Yong Chen, Xiao‐Zhong Chen, Xiao‐Jing Du, Wen‐Feng Fang, Mei Feng, Jin Gao, Fei Han, Xia He, Chao‐Su Hu, De‐sheng Hu, Guang‐Yuan Hu, Hao Jiang, Wei Jiang, Feng Jin, Jin‐Yi Lang, Jin‐Gao Li, Shao‐Jun Lin, Xu Liu, Qiu‐Fang Liu, Lin Ma, Hai‐Qiang Mai, Ji‐Yong Qin, Liang‐Fang Shen, Ying Sun, Pei‐Guo Wang, Ren‐Sheng Wang, Ruo‐Zheng Wang, Xiao‐Shen Wang, Ying Wang, Hui Wu, Yun‐Fei Xia, Shao‐Wen Xiao, Kun‐Yu Yang, Jun‐Lin Yi, Xiao‐Dong Zhu, Jun Ma

Source: Cancer Communications, Vol 41, Iss 11, Pp 1195-1227 (2021)

Subject Terms: Chinese Society of Clinical Oncology, CSCO, Nasopharyngeal carcinoma, Diagnosis, Staging, Risk, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2523-3548

Access URL: https://doaj.org/article/d1b3df74dd3845eea72df7182aab876b

Advances in pathogenesis and precision medicine for nasopharyngeal carcinoma

Authors: Qian‐Ying Zhu, Ge‐Xin Zhao, Yan Li, Girish Talakatta, Hai‐Qiang Mai, Quynh‐Thu Le, Lawrence S. Young, Mu‐Sheng Zeng

Source: MedComm, Vol 2, Iss 2, Pp 175-206 (2021)

Subject Terms: Epstein‐Barr virus, nasopharyngeal carcinoma, precision medicine, signal transduction, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2688-2663

Access URL: https://doaj.org/article/5012eac8ba794ed781b5464cf1160b49

Subdivision of de-novo metastatic nasopharyngeal carcinoma based on tumor burden and pretreatment EBV DNA for therapeutic guidance of locoregional radiotherapy

Authors: Jin-Hao Yang, Xue-Song Sun, Bei-Bei Xiao, Li-Ting Liu, Shan-Shan Guo, Jia-Dong Liang, Guo-Dong Jia, Lin-Quan Tang, Qiu-Yan Chen, Hai-Qiang Mai

Source: BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)

Subject Terms: Nasopharyngeal carcinoma, Distant metastasis, Locoregional radiotherapy, EBV DNA, Risk stratifications, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/e1984a3db8f94e669f060298fb35b33f