Identification and characterisation of novel mammalian homologues of Drosophila polyhomeotic permits new insights into relationships between members of the polyhomeotic family.

Authors: Tonkin, Emma, Hagan, Donna-Marie, Li, Weiping, Strachan, Tom

Source: Human Genetics; Oct2002, Vol. 111 Issue 4/5, p435-442, 8p

Subject Terms: DROSOPHILA, HOMEOBOX genes, HUMAN genetics, GENOMES, BIOLOGICAL classification, HUMAN heredity, HUMAN biology

A homeobox gene, HLXB9, is the major locus for dominantly inherited sacral agenesis.

Authors: Ross, Alison J., Ruiz-Perez, Victor, Wang, Yiming, Hagan, Donna-Marie, Scherer, Steve, Lynch, Sally A., Lindsay, Susan, Custard, Emily, Belloni, Elena, Wilson, David I., Wadey, Roy, Goodman, Frances, Orstavik, Karen Helene, Monclair, Tom, Robson, Steve, Reardon, William, Burn, John, Scambler, Pete, Strachan, Tom

Source: Nature Genetics; Dec98, Vol. 20 Issue 4, p358, 4p

Subject Terms: SACRUM, CHROMOSOMES, HOMEOBOX genes, GENETIC disorders