Efficacy of cold and cryo-preserved nerve allografts with low-dose FK506 for motor nerve regeneration: a preclinical study

Authors: Jong Pil Kim, Soon Chul Heo, Dae Hee Lee, Jun Sang Bae, Young Kwang Shin, Su Hyeok Son, Il Yong Park, Hae-Won Kim, Jun Hee Lee, Kyung Wook Kim

Source: Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-13 (2024)

Subject Terms: Cryopreservation, Cold preservation, Allograft, Immunosuppression, Nerve reconstruction, FK506, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1749-799X

Access URL: https://doaj.org/article/23523df006f84621b30951a1c2c07ad6

Adaptive immunity of materials: Implications for tissue healing and regeneration

Authors: Jung-Hwan Lee, Seong-Jin Shin, Jun Hee Lee, Jonathan C. Knowles, Hae-Hyoung Lee, Hae-Won Kim

Source: Bioactive Materials, Vol 41, Iss , Pp 499-522 (2024)

Subject Terms: Adaptive immunity, Materials interactions, Tissue healing, Physicochemical properties, Immune cell interplay, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X24003104; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/e9534607330048948702666225d4cf22

Matrix‐Rigidity Cooperates With Biochemical Cues in M2 Macrophage Activation Through Increased Nuclear Deformation and Chromatin Accessibility

Authors: Seung Jae Shin, Buuvee Bayarkhangai, Khaliunsarnai Tsogtbaatar, Meng Yuxuan, Sang‐Hyun Kim, Yong‐Jae Kim, Ali Taghizadeh, Daesan Kim, Dong‐Hwee Kim, Jung‐Hwan Lee, Jeongeun Hyun, Hae‐Won Kim

Source: Advanced Science, Vol 12, Iss 8, Pp n/a-n/a (2025)

Subject Terms: chromatin accessibility, macrophage activation, matrix rigidity, mechano‐chemical signaling, nuclear mechanosensing, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/5dfe693628814db79f7b4e4acd406cce

In vitro and ex vivo models of the oral mucosa as platforms for the validation of novel drug delivery systems

Authors: Robyn A Macartney, Abijit Das, Atina G Imaniyyah, Annabelle TR Fricker, Andrew M Smith, Stefano Fedele, Ipsita Roy, Hae-Won Kim, Dongjoon Lee, Jonathan C Knowles

Source: Journal of Tissue Engineering, Vol 16 (2025)

Subject Terms: Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2041-7314

Access URL: https://doaj.org/article/83912deecb434b9180ebe53c259e4346

Corrigendum to ‘Cyclic stretch-induced epigenetic activation of periodontal ligament cells’ [Mater. Today Bio 26 (2024), 101050]

Authors: Han-Jin Bae, Seong-Jin Shin, Seung Bin Jo, Cheng Ji Li, Dong-Joon Lee, Jun-Hee Lee, Hae-Hyoung Lee, Hae-Won Kim, Jung-Hwan Lee

Source: Materials Today Bio, Vol 29, Iss , Pp 101277- (2024)

Subject Terms: Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590006424003387; https://doaj.org/toc/2590-0064

Access URL: https://doaj.org/article/f881616e8c8341579cb9814329e6c12e

Titanium-doped phosphate glasses containing zinc and strontium applied in bone regeneration

Authors: Tianyi Tang, Rachel Wandless, Zalike Keskin-Erdogan, Nandin-Erdene Mandakhbayar, Jeong-Hui Park, Hae-Won Kim, Morgana Abramchuk, Felipe P. Daltoe, Jonathan C. Knowles

Source: Journal of Materials Science: Materials in Medicine, Vol 35, Iss 1, Pp 1-10 (2024)

Subject Terms: Materials of engineering and construction. Mechanics of materials, TA401-492, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1573-4838

Access URL: https://doaj.org/article/ee1aaa0f93ea41338f184b99a7c9cdfb

Chaga mushroom extract suppresses oral cancer cell growth via inhibition of energy metabolism

Authors: Donghyeon Yeo, Yeo Gyun Yun, Seong-Jin Shin, Khandmaa Dashnyam, Anand Khurelbaatar, Jun Hee Lee, Hae-Won Kim

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Subject Terms: Chaga mushroom extract, Oral cancer cell, Cancer progression, Glycolysis, Mitochondrial respiration, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/321282b6bccd410998c0f924eeba4067

Establishing Minimum Criteria for Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs) Cultured in Human Platelet Lysate (hPL)-Contained Media as Cell Therapy Candidates: Characterization and Predictive Analysis of Secretome Effects

Authors: Ji-Young Yoon, Bình Do Quang, Ji-Sun Shin, Jong-Bin Kim, Jun Hee Lee, Hae-Won Kim, Jung-Hwan Lee

Source: Cells, Vol 14, Iss 4, p 316 (2025)

Subject Terms: SHED, DPSC, hPL, cell therapy, stem cell characterization, standards for cell therapy, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/14/4/316; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/de9f5c1e3dd742dda57d412090f9a793

Tissue Mechanics and Hedgehog Signaling Crosstalk as a Key Epithelial–Stromal Interplay in Cancer Development

Authors: Shanika Karunasagara, Ali Taghizadeh, Sang‐Hyun Kim, So Jung Kim, Yong‐Jae Kim, Mohsen Taghizadeh, Moon‐Young Kim, Kyu‐Young Oh, Jung‐Hwan Lee, Hye Sung Kim, Jeongeun Hyun, Hae‐Won Kim

Source: Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)

Subject Terms: cancer development, chemomechanical cues, epithelial–stroma interplay, hedgehog, tissue stiffness, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/5d9ed89cb8184bc5be14e2bdcc15a4b7

Neural Tissue‐Like, not Supraphysiological, Electrical Conductivity Stimulates Neuronal Lineage Specification through Calcium Signaling and Epigenetic Modification

Authors: Yu‐Meng Li, Yunseong Ji, Yu‐Xuan Meng, Yu‐Jin Kim, Hwalim Lee, Amal George Kurian, Jeong‐Hui Park, Ji‐Young Yoon, Jonathan C. Knowles, Yunkyu Choi, Yoon‐Sik Kim, Bo‐Eun Yoon, Rajendra K. Singh, Hae‐Hyoung Lee, Hae‐Won Kim, Jung‐Hwan Lee

Source: Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)

Subject Terms: calcium signaling, electrical conductivity, epigenetic change, neural lineage specification, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/d3f7b2a333ba455288ce4265a6dfcab3

Nanozyme-Engineered Hydrogels for Anti-Inflammation and Skin Regeneration

Authors: Amal George Kurian, Rajendra K. Singh, Varsha Sagar, Jung-Hwan Lee, Hae-Won Kim

Source: Nano-Micro Letters, Vol 16, Iss 1, Pp 1-53 (2024)

Subject Terms: Nanozymes, Hydrogels, ROS scavenging, Anti-inflammation, Skin regeneration, Technology

File Description: electronic resource

Relation: https://doaj.org/toc/2311-6706; https://doaj.org/toc/2150-5551

Access URL: https://doaj.org/article/a942dc17c76747f58aa8ccd4d157a684

Double hits with bioactive nanozyme based on cobalt-doped nanoglass for acute and diabetic wound therapies through anti-inflammatory and pro-angiogenic functions

Authors: Nandin Mandakhbayar, YunSeong Ji, Ahmed El-Fiqi, Kapil D. Patel, Dong Suk Yoon, Khandmaa Dashnyam, Oyunchimeg Bayaraa, Gangshi Jin, Khaliunsarnai Tsogtbaatar, Tae-Hyun Kim, Jung-Hwan Lee, Hae-Won Kim

Source: Bioactive Materials, Vol 31, Iss , Pp 298-311 (2024)

Subject Terms: Diabetic wound, Nanozyme, Anti-inflammation, Angiogenesis, Therapeutic materials, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X23002530; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/7d1729ee6c9549d6840f8ed5149d543a

Chronic Opioid Treatment Arrests Neurodevelopment and Alters Synaptic Activity in Human Midbrain Organoids

Authors: Hye Sung Kim, Yang Xiao, Xuejing Chen, Siyu He, Jongwon Im, Moshe J. Willner, Michael O. Finlayson, Cong Xu, Huixiang Zhu, Se Joon Choi, Eugene V. Mosharov, Hae‐Won Kim, Bin Xu, Kam W. Leong

Source: Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)

Subject Terms: brain organoid, fentanyl, neurodevelopment, opioid, single‐cell RNA sequencing, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/b46900ca4b6748a09f94984845285e8f

Cyclic stretch induced epigenetic activation of periodontal ligament cells

Authors: Han-Jin Bae, Seong-Jin Shin, Seung Bin Jo, Cheng Ji Li, Dong-Joon Lee, Jun-Hee Lee, Hae-Hyoung Lee, Hae-Won Kim, Jung-Hwan Lee

Source: Materials Today Bio, Vol 26, Iss , Pp 101050- (2024)

Subject Terms: Biophysical cues, Periodontal ligament cell, Lineage specification, Euchromatin status, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590006424001091; https://doaj.org/toc/2590-0064

Access URL: https://doaj.org/article/9a8159e69bc04568a6f64499fad1b5ef

Targeting Nuclear Mechanics Mitigates the Fibroblast Invasiveness in Pathological Dermal Scars Induced by Matrix Stiffening

Authors: Xiangting Fu, Ali Taghizadeh, Mohsen Taghizadeh, Cheng Ji Li, Nam Kyu Lim, Jung‐Hwan Lee, Hye Sung Kim, Hae‐Won Kim

Source: Advanced Science, Vol 11, Iss 15, Pp n/a-n/a (2024)

Subject Terms: cell migration, cellular mechanosensing, matrix stiffness, nuclear lamin, pathological dermal scar, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/4f09ac006026481e99c86fe032a98ad6

Selective Suppression of Integrin‐Ligand Binding by Single Molecular Tension Probes Mediates Directional Cell Migration

Authors: Seong‐Beom Han, Geonhui Lee, Daesan Kim, Jeong‐Ki Kim, In‐San Kim, Hae‐Won Kim, Dong‐Hwee Kim

Source: Advanced Science, Vol 11, Iss 14, Pp n/a-n/a (2024)

Subject Terms: cell adhesion, FAK phosphorylation, integrin αvβ3, molecular tension probes, persistent migration, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/97c8d97bf6444d42851bcd75b7f2f6c9

Biosubstitutes for dural closure: Unveiling research, application, and future prospects of dura mater alternatives

Authors: Dolphee Khurana, Ankitha Suresh, Raghavendra Nayak, Manjunath Shetty, Rohit Kumar Sarda, Jonathan C Knowles, Hae-Won Kim, Rajendra K Singh, Bhisham Narayan Singh

Source: Journal of Tissue Engineering, Vol 15 (2024)

Subject Terms: Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2041-7314

Access URL: https://doaj.org/article/1652a39a39754f3580f139434561c9b7

Dendritic cell-mimicking scaffolds for ex vivo T cell expansion

Authors: Hye Sung Kim, Tzu-Chieh Ho, Moshe J. Willner, Michael W. Becker, Hae-Won Kim, Kam W. Leong

Source: Bioactive Materials, Vol 21, Iss , Pp 241-252 (2023)

Subject Terms: Adoptive cell therapy, Ex vivo T cell expansion, Cytotoxic T cell, Dendritic cell membrane, Cell membrane coating, Scaffold, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X22003589; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/0906ac8908a34bbaaface5029651fdba

Materials and extracellular matrix rigidity highlighted in tissue damages and diseases: Implication for biomaterials design and therapeutic targets

Authors: Jae Hee Park, Seung Bin Jo, Jung-Hwan Lee, Hae-Hyoung Lee, Jonathan C. Knowles, Hae-Won Kim

Source: Bioactive Materials, Vol 20, Iss , Pp 381-403 (2023)

Subject Terms: Matrix rigidity, Biophysical cue, Cell and tissue engineering, 3D biomaterials conditions, Therapeutic targets, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X22002699; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/6dbe634a85ee424293f2e7fbb6d6a5c1

Cyclic Stretch Promotes Cellular Reprogramming Process through Cytoskeletal‐Nuclear Mechano‐Coupling and Epigenetic Modification

Authors: Sung‐Min Park, Jung‐Hwan Lee, Kwang Sung Ahn, Hye Won Shim, Ji‐Young Yoon, Jeongeun Hyun, Jun Hee Lee, Sunyoung Jang, Kyung Hyun Yoo, Yoon‐Kwan Jang, Tae‐Jin Kim, Hyun Kyu Kim, Man Ryul Lee, Jun‐Hyeog Jang, Hosup Shim, Hae‐Won Kim

Source: Advanced Science, Vol 10, Iss 32, Pp n/a-n/a (2023)

Subject Terms: cell reprogramming, epigenetic change, induced pluripotent stem cells, mechanotransduction, physical force, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/e33d70cb762d44bd8b98683ebb4a70ba