Hydroxychloroquine in combination with platinum doublet chemotherapy as first-line treatment for extensive-stage small cell lung cancer (Study 15): A randomised phase II multicentre trial

Authors: Lee, Siow Ming ^{a, n, o, ⁎, 1}, Hewish, Madeleine ^b, Ahmed, Samreen ^c, Papadatos-Pastos, Dionysis ^{a, d}, Karapanagiotou, Eleni ^e, Blackhall, Fiona ^f, Ford, Amy ^g, Young, Robin ^h, Garcia, Angel ⁱ, Arora, Arvind ^j, Hollingdale, Abigail ^k, Ahmad, Tanya ^a, Forster, Martin ^a, Greystoke, Alastair ^l, Bremner, Fion ^m, Rudd, Robin ⁿ, Farrelly, Laura ^o, Vaja, Simran ^o, Hackshaw, Allan ^o

Source: In European Journal of Cancer 17 January 2025 215

Induction chemotherapy followed by standard chemoradiotherapy versus standard chemoradiotherapy alone in patients with locally advanced cervical cancer (GCIG INTERLACE): an international, multicentre, randomised phase 3 trial

Authors: Reed, Nicholas, Drake, Anne, Bashir, Faheem, Cook, Audrey, Mandal, Ranajit, Barraclough, Lisa, Dubey, Sidarth, Park, Won-Ho Edward, Pilar, Maria, Gallardo, Dolores, Alamilla-Garcia, Gabriela, Colombo, Nicoletta, Adusumalli, Madhavi, Kent, Christopher, Panades, Miguel, King, Margaret, Wade, Robert, Forrest, Jennifer, Mak, Choi, Anand, Anjana, McGrane, John, Persic, Mojca, Bhana, Rajanee, Lankester, Kate, Chowdhury, Rahul Roy, McFarlane, Vicky, Powell, Melanie, Whitmarsh, Karen, McCormack, Mary, Eminowicz, Gemma, Hudson, Emma, Mathew, Tony, Diez, Patricia ^c, Farrelly, Laura ^d, Mukhopadhyay, Asima ^p, Chávez-Blanco, Adriana ^x, Stobart, Hilary ^y, Feeney, Amanda ^d, Vaja, Simran ^d, Hacker, Anne-Marie ^d, Hackshaw, Allan ^d, Ledermann, Jonathan Andrew ^d

Source: In The Lancet 19-25 October 2024 404(10462):1525-1535

Urinary biomarkers in metastatic bone pain: Results from a multicentre randomized trial of ibandronate compared to single dose radiotherapy for localized metastatic bone pain in prostate cancer (RIB)

Authors: Hoskin, P.J., Malhi, Aman, Reczko, Krystyna, Hackshaw, Allan

Source: In Journal of Bone Oncology August 2024 47

Radiation Dose Be Personalized in Patients With Localized NSCLC and Actionable Genetic Alterations? Insight From a Multicenter Real-World Study

Authors: Ashraf, Salman, Khan, Madeha, Naguib, Nada, Rulach, Robert, Welsh, Katharine, Carozzi, Rebecca, Horne, Ashley, Payne, Amelia, Jones, Sarah Bowen, Denholm, Mary, Stewart, Georgia, Bedair, Ahmed, Lindsay, Colin R., Harrow, Stephen, Faivre-Finn, Corinne, McAleese, Jonathan, Hanna, Gerard G., Hackshaw, Allan, McDonald, Fiona, Walls, Gerard M.

Source: In JTO Clinical and Research Reports November 2024

The SUMMIT Study: Utilising a written 'Next Steps' information booklet to prepare participants for potential lung cancer screening results and follow-up

Authors: Bhamani, Amyn, Horst, Carolyn, Bojang, Fanta, Quaife, Samantha L, Dickson, Jennifer L, Tisi, Sophie, Hall, Helen, Verghese, Priyam, Creamer, Andrew, Prendecki, Ruth, McCabe, John, Gyertson, Kylie, Bowyer, Vicky, El-Emir, Ethaar, Cotton, Alice, Mehta, Simranjit, Levermore, Claire, Mullin, Anne-Marie, Teague, Jonathan, Farrelly, Laura, Nair, Arjun, Devaraj, Anand, Hackshaw, Allan, Janes, Sam M

Source: Lung cancer. 176:75-81

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185607846.0x000001&indx=1&recIds=ETOCvdc_100185607846.0x000001

Uptake of invitations to a lung health check offering low-dose CT lung cancer screening among an ethnically and socioeconomically diverse population at risk of lung cancer in the UK (SUMMIT): a prospective, longitudinal cohort study

Authors: Dickson, Jennifer L, Hall, Helen, Horst, Carolyn, Tisi, Sophie, Verghese, Priyam, Mullin, Anne-Marie, Teague, Jon, Farrelly, Laura, Bowyer, Vicky, Gyertson, Kylie, Bojang, Fanta, Levermore, Claire, Anastasiadis, Tania, McCabe, John, Navani, Neal, Nair, Arjun, Devaraj, Anand, Hackshaw, Allan, Quaife, Samantha L, Janes, Sam M

Source: Lancet.Public health. 8(2):e130-e140

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179821691.0x000001&indx=1&recIds=ETOCvdc_100179821691.0x000001

Concept: A randomised multicentre trial of first line chemotherapy comparing three weekly cabazitaxel versus weekly paclitaxel in HER2 negative metastatic breast cancer

Authors: Bahl, Amit, Wilson, William, Ball, Jessica, Renninson, Emily, Dubey, Sidharth, Bravo, Alicia, Foulstone, Emily, Spensley, Saiqa, Bowen, Rebecca, Mansi, Janine, Waters, Simon, Riddle, Pippa, Wheatley, Duncan, Stephens, Peter, Bezecny, Pavel, Madhusudan, Srinivasan, Verrill, Mark, Braybrooke, Jeremy, Comins, Charles, Mohan, Vivek, Gee, Abigail, Kirk, Hannah, Markham, Alison, Evans, Heidi, Watson, Eve, Callaway, Mark, Pearson, Sylvia, Hackshaw, Allan, Churn, Mark

Source: In The Breast December 2022 66:69-76

Utilisation of primary care electronic patient records for identification and targeted invitation of individuals to a lung cancer screening programme

Authors: Dickson, Jennifer L., Hall, Helen, Horst, Carolyn, Tisi, Sophie, Verghese, Priyam, Worboys, Sarah, Perugia, Andrew, Rusius, James, Mullin, Anne-Marie, Teague, Jonathan, Farrelly, Laura, Bowyer, Vicky, Gyertson, Kylie, Bojang, Fanta, Levermore, Claire, Anastasiadis, Tania, McCabe, John, Devaraj, Anand, Nair, Arjun, Navani, Neal, Hackshaw, Allan, Quaife, Samantha L., Janes, Sam M.

Source: Lung cancer. 173:94-100

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184960639.0x000001&indx=1&recIds=ETOCvdc_100184960639.0x000001

Prognostic factors for survival and ambulatory status at 8 weeks with metastatic spinal cord compression in the SCORAD randomised trial

Authors: Hoskin, Peter J., Hopkins, Kirsten, Misra, Vivek, Holt, Tanya, McMenemin, Rhona, McKinna, Fiona, Madhavan, Krishnaswamy, Bates, Andrew, O'Rourke, Noelle, Lester, Jason F., Sevitt, Tim, Roos, Daniel, Brown, Gillian, Thomas, Sharon Shibu, Forsyth, Sharon, Reczko, Krystyna, Hackshaw, Allan, O'Hara, Catherine, Lopes, Andre

Source: Radiotherapy and oncology. 173:77-83

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173152088.0x000001&indx=1&recIds=ETOCvdc_100173152088.0x000001

The reporting of pulmonary nodule results by letter in a lung cancer screening setting

Authors: Dickson, Jennifer L, Bhamani, Amyn, Quaife, Samantha L, Horst, Carolyn, Tisi, Sophie, Hall, Helen, Verghese, Priyam, Creamer, Andrew, Prendecki, Ruth, McCabe, John, Gyertson, Kylie, Bowyer, Vicky, El-Emir, Ethaar, Cotton, Alice, Mehta, Simranjit, Bojang, Fanta, Levermore, Claire, Mullin, Anne-Marie, Teague, Jonathan, Farrelly, Laura, Nair, Arjun, Devaraj, Anand, Hackshaw, Allan, Janes, Sam M

Source: Lung cancer. 168:46-49

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164150688.0x000001&indx=1&recIds=ETOCvdc_100164150688.0x000001

New genomic technologies for multi-cancer early detection: Rethinking the scope of cancer screening

Authors: Hackshaw, Allan, Clarke, Christina A., Hartman, Anne-Renee

Source: Cancer cell. 40(2):109-113

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100158365317.0x000001&indx=1&recIds=ETOCvdc_100158365317.0x000001

Long term efficacy of first-line afatinib and the clinical utility of ctDNA monitoring in patients with suspected or confirmed EGFR mutant non-small cell lung cancer who were unsuitable for chemotherapy: Clinical Studies.

Authors: Popat, Sanjay, Januszewski, Adam, O'Brien, Mary, Ahmad, Tanya, Lewanski, Conrad, Dernedde, Ulrike, Jankowska, Petra, Mulatero, Clive, Shah, Riyaz, Hicks, Jonathan, Geldart, Tom, Cominos, Mathilda, Gray, Gill, Spicer, James, Bell, Karen, Roitt, Simon, Morris, Clive, Ngai, Yenting, Hughes, Laura, Hackshaw, Allan

Source: British Journal of Cancer; Feb2025, Vol. 132 Issue 3, p245-252, 8p

Psychological Targets for Lung Cancer Screening Uptake: A Prospective Longitudinal Cohort Study

Authors: Quaife, Samantha L., Waller, Jo, Dickson, Jennifer L., Brain, Kate E., Kurtidu, Clara, McCabe, John, Hackshaw, Allan, Duffy, Stephen W., Janes, Samuel M.

Source: In Journal of Thoracic Oncology December 2021 16(12):2016-2028

Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma

Authors: Abbosh, Chris, Shiu, Kai-Keen, Bridgewater, John, Hochhauser, Daniel, Forster, Martin, Lee, Siow-Ming, Ahmad, Tanya, Papadatos-Pastos, Dionysis, Janes, Sam, Van Loo, Peter, Enfield, Katey, McGranahan, Nicholas, Huebner, Ariana, Beck, Stephan, Parker, Peter, Walczak, Henning, Enver, Tariq, Hynds, Rob, Sinclair, Ron, Lok, Chi-wah, Rhodes, Zoe, Moore, David, Khiroya, Reena, Trevisan, Giorgia, Ellery, Peter, Linch, Mark, Brandner, Sebastian, Hiley, Crispin, Veeriah, Selvaraju, Razaq, Maryam, Shaw, Heather, Attard, Gert, Akther, Mita Afroza, Naceur-Lombardelli, Cristina, Manzano, Lizi, Al-Bakir, Maise, Summan, Simranpreet, Kanu, Nnenna, Ward, Sophie, Asghar, Uzma, Lim, Emilia, Gishen, Faye, Tookman, Adrian, Stone, Paddy, Stirling, Caroline, Hunter, Nikki, Vaughan, Sarah, Mangwende, Mary, Spain, Lavinia, Yan, Haixi, Shum, Ben, Carlyle, Eleanor, Yousaf, Nadia, Popat, Sanjay, Curtis, Olivia, Stamp, Gordon, Toncheva, Antonia, Nye, Emma, Murra, Aida, Korteweg, Justine, Josephs, Debra, Chandra, Ashish, Spicer, James, Stewart, Ruby, Iredale, Lara-Rose, Mackay, Tina, Deakin, Ben, Enting, Debra, Rudman, Sarah, Ghosh, Sharmistha, Karapagniotou, Lena, Pintus, Elias, Tutt, Andrew, Howlett, Sarah, Michalarea, Vasiliki, Brenton, James, Caldas, Carlos, Fitzgerald, Rebecca, Jimenez-Linan, Merche, Provenzano, Elena, Cluroe, Alison, Stewart, Grant, Watts, Colin, Gilbertson, Richard, McDermott, Ultan, Tavare, Simon, Beddowes, Emma, Roxburgh, Patricia, Biankin, Andrew, Chalmers, Anthony, Fraser, Sioban, Oien, Karin, Kidd, Andrew, Blyth, Kevin, Krebs, Matt, Blackhall, Fiona, Summers, Yvonne, Dive, Caroline, Marais, Richard, Gomes, Fabio, Carter, Mat, Dransfield, Jo, Le Quesne, John, Fennell, Dean, Shaw, Jacqui, Naidu, Babu, Baijal, Shobhit, Tanchel, Bruce, Langman, Gerald, Robinson, Andrew, Collard, Martin, Cockcroft, Peter, Ferris, Charlotte, Bancroft, Hollie, Kerr, Amy, Middleton, Gary, Webb, Joanne, Kadiri, Salma, Colloby, Peter, Olisemeke, Bernard, Wilson, Rodelaine, Tomlinson, Ian, Jogai, Sanjay, Ottensmeier, Christian, Harrison, David, Loda, Massimo, Flanagan, Adrienne, McKenzie, Mairead, Hackshaw, Allan, Ledermann, Jonathan, Chan, Kitty, Sharp, Abby, Farrelly, Laura, Bridger, Hayley, Challacombe, Ben, Chowdhury, Simon, Drake, William, Fernando, Archana, Harrison-Phipps, Karen, Hazell, Steve, Hill, Peter, Horsfield, Catherine, O'Brien, Tim, Olsburgh, Jonathon, Polson, Alexander, Varia, Mary, Verma, Hema, Au, Lewis, Hatipoglu, Emine, Robert de Massy, Marc, Litchfield, Kevin, Beattie, Gordon, Rowan, Andrew, Schnidrig, Desiree, Thompson, Rachael, Byrne, Fiona, Horswell, Stuart, Fotiadis, Nicos, Nicol, David, Shepherd, Scott T.C., Fendler, Annika, Mason, Robert, Del Rosario, Lyra, Edmonds, Kim, Lingard, Karla, Sarker, Sarah, Attig, Jan, Joshi, Kroopa, Uddin, Imran, Becker, Pablo D., Sunderland, Mariana Werner, Akarca, Ayse, Puccio, Ignazio, Yang, William W., Lund, Tom, Dhillon, Kim, Vasquez, Marcos Duran, Ghorani, Ehsan, Xu, Hang, Spencer, Charlotte, López, José I., Green, Anna, Mahadeva, Ula, Borg, Elaine, Mitchison, Miriam, Moore, David A., Proctor, Ian, Falzon, Mary, Pickering, Lisa, Furness, Andrew J.S., Reading, James L., Salgado, Roberto, Marafioti, Teresa, Jamal-Hanjani, Mariam, Kassiotis, George, Chain, Benny, Larkin, James, Swanton, Charles, Quezada, Sergio A., Turajlic, Samra

Source: In Cancer Cell 8 November 2021 39(11):1497-1518

Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma

Authors: Black, James R. M., Bartha, Gabor, Abbott, Charles W., Boyle, Sean M., Karasaki, Takahiro, Li, Bailiang, Chen, Rui, Harris, Jason, Veeriah, Selvaraju, Colopi, Martina, Bakir, Maise Al, Liu, Wing Kin, Lyle, John, Navarro, Fábio C. P., Northcott, Josette, Pyke, Rachel Marty, Hill, Mark S., Thol, Kerstin, Huebner, Ariana, Bailey, Chris, Colliver, Emma C., Martínez-Ruiz, Carlos, Grigoriadis, Kristiana, Pawlik, Piotr, Moore, David A., Marinelli, Daniele, Shutkever, Oliver G., Murphy, Cian, Sivakumar, Monica, Shaw, Jacqui A., Hackshaw, Allan, McGranahan, Nicholas, Jamal-Hanjani, Mariam, Frankell, Alexander M., Chen, Richard O., Swanton, Charles

Source: Nature Medicine; 20250101, Issue: Preprints p1-7, 7p

A feasibility trial of acupuncture in cancer patients undergoing radiotherapy treatment

Authors: Hughes, John, Gyertson, Kylie, Carballo, Lallita, Plant, Hilary, Sharman, Mitch, Ruane, Katie, Mendoza-Naranjo, Ariadna, Hackshaw, Allan, Cummings, Mike, Edwards, Alex, Lewith, George, Fisher, Peter

Source: In Complementary Therapies in Clinical Practice May 2021 43

Chemotherapy and radiotherapy in locally advanced head and neck cancer: an individual patient data network meta-analysis

Authors: Adelstein, D.J., Agarwal, J., Alfonsi, M., Argiris, A., Aupérin, A., Bacigalupo, A., Bar-Ad, V., Bartelink, H., Beadle, B., Belkacemi, Y., Bensadoun, R.J., Bernier, J., Blanchard, P., Bourhis, J., Bratland, Å., Brizel, D., Budach, V., Budach, W., Burtness, B., Calais, G., Campbell, B., Caudell, J., Chabaud, S., Chamorey, E., Chaukar, D., Cheugoua-Zanetsie, M., Cho, K.H., Choussy, O., Cruz Hernandez, J.J., Denham, J.W., Dobrowsky, W., Dominello, M.M, Driessen, C.M.L., Fallai, C., Forastiere, A.A., Fortpied, C., Fountzilas, G., Garaud, P., Garden, A.S., Gery, B., Ghadjar, P., Ghi, M.G., Ghosh Laskar, S., Graff-Cailleaud, P., Grau, C., Gregoire, V., Hackshaw, A., Haddad, E, Haffty, B.G., Hansen, A., Hay, J.H., Hayoz, S., Horiot, J.C., Hitt, R., Jeremic, B., Johansen, J., Jones, C., Julieron, M., Kristensen, C.A., Kumar, S., Lacas, B., Langendijk, J.A., Lapeyre, M., Lartigau, E., Licitra, L., Le, Q.T., Lee, J.W., Lee, P., Lewin, F., Li, Y., Lopes, A., Lotayef, M., Maciejewski, B., Mazeron, J.J., Mehta, S., Michalski, W., Moon, J., Moon, S.H., Moyal, E., Nankivell, M., Nilsson, P., Olmi, P., Orecchia, R., O'Sullivan, B., Overgaard, J., Parmar, M.K.B., Petit, C., Pignon, J.P., Pointreau, Y., Posner, M.R., Poulsen, M.G., Quon, H., Racadot, S., Rosenthal, D.I., Rovea, P., Ruo Redda, M.G., Sanguineti, G., Shenouda, G., Simes, J., Sharma, A., Simon, C., Sire, C., Skladowski, K., Spencer, S., Staar, S., Strojan, P., Stromberger, C., Suwinski, R., Szutkowski, Z., Takácsi-Nagy, Z., Tao, Y.G., Temam, S., Thomson, D., Tobias, J.S., Torres-Saavedra, P., Torri, V., Tripcony, L., Trotti, A., Tseroni, V., van Herpen, C., van Tinteren, H., Vermorken, J., Viegas, C.M.P., Vokes, E.E., Waldron, J., Wernecke, K.D, Widder, J., Wolf, G.T., Wong, S.J., Wu, J.S., Yamazaki, H., Zaktonik, B., Zackrisson, B., Zhong, L.P., Petit, Claire, Lacas, Benjamin, Pignon, Jean-Pierre, Le, Quynh Thu, Grégoire, Vincent, Grau, Cai, Hackshaw, Allan, Zackrisson, Björn, Parmar, Mahesh K B, Lee, Ju-Whei, Ghi, Maria Grazia, Sanguineti, Giuseppe, Temam, Stéphane, Cheugoua-Zanetsie, Maurice, O'Sullivan, Brian, Posner, Marshall R, Vokes, Everett E, Cruz Hernandez, Juan J, Szutkowski, Zbigniew, Lartigau, Eric, Budach, Volker, Suwiński, Rafal, Poulsen, Michael, Kumar, Shaleen, Ghosh Laskar, Sarbani, Mazeron, Jean-Jacques, Jeremic, Branislav, Simes, John, Zhong, Lai-Ping, Overgaard, Jens, Fortpied, Catherine, Torres-Saavedra, Pedro, Bourhis, Jean, Aupérin, Anne, Blanchard, Pierre ^*

Source: In The Lancet Oncology May 2021 22(5):727-736

The effect of clinical decision making for initiation of systemic anticancer treatments in response to the COVID-19 pandemic in England: a retrospective analysis

Authors: Clark, James J, Dwyer, Dominic, Pinwill, Nina, Clark, Peter, Johnson, Peter, Hackshaw, Allan

Source: Lancet oncology. 22(1):66-73

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135867204.0x000001&indx=1&recIds=ETOCvdc_100135867204.0x000001

Risk stratification in breast screening workshop.

Authors: Anderson, Andrew, Visintin, Cristina, Antoniou, Antonis, Pashayan, Nora, Gilbert, Fiona J., Hackshaw, Allan, Bhatt, Rikesh, Hill, Harry, Wright, Stuart, Payne, Katherine, Rogers, Gabriel, Shinkins, Bethany, Taylor-Phillips, Sian, Given-Wilson, Rosalind

Source: BMC Proceedings; 10/24/2024, Vol. 18 Issue 19, p1-9, 9p

Subject Terms: MEDICAL screening, DIGITAL technology, EVIDENCE gaps, EPIDEMIOLOGY of cancer, EARLY detection of cancer

The adapted Zelen was a feasible design to trial exercise in myeloma survivors

Authors: Land, Joanne, McCourt, Orla, Heinrich, Malgorzata, Beeken, Rebecca J., Koutoukidis, Dimitrios A., Paton, Bruce, Yong, Kwee, Hackshaw, Allan, Fisher, Abigail

Source: In Journal of Clinical Epidemiology September 2020 125:76-83