0.5 Gy confers resistance to a subsequent high dose of γ-rays by modulating HO-1/Nrf2 and apoptosis pathways

Authors: Yasser F. Ali, Ibrahim M. Hassan, Hussein M. Abdelhafez, Omar S. Desouky

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-10 (2025)

Subject Terms: Adaptive response, 0.5 Gy, HMOX1, Low dose, Apoptosis pathways, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/c6878bdf79ba4a9292db6920cbb12cb7

Fascia-derived stem cells enhance fat graft retention by promoting vascularization through the HMOX1-HIF-1α pathway

Authors: Guo Chen, Jie Long, Yuge Zhang, Xuhua Zhou, Botao Gao, Zijin Qin, Yuhan Zhu, Binyu Song, Ziwei Cui, Zhangzi liu, Man Xu, Zhou Yu, Baoqiang Song, Ziang Zhang

Source: Stem Cell Research & Therapy, Vol 16, Iss 1, Pp 1-21 (2025)

Subject Terms: Superficial Fascia, Stem cells, Vascularization, Graft Retention, HMOX1, HIF-α, Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/29cc3669aa064d66b55ce56487e3cc35

Bio-nanocomplexes impair iron homeostasis to induce non-canonical ferroptosis in cancer cells

Authors: Xin Wang, Tianyi Zhang, Shuai Wang, Hanping Shi, Hong Dong, Yanning Huang, Wenjia Lai, Yiqiao Hu, Chunyan Yue

Source: Journal of Nanobiotechnology, Vol 23, Iss 1, Pp 1-14 (2025)

Subject Terms: Non-canonical ferroptosis, Iron homeostasis, HMOX1, Bio-nanocomplex, CBS, Labile iron pool, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/0e40b54513f34cfc8b8d39c16658c8b7

CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis

Authors: Yan Xi, Niu Yinghao, Wang Yaojie, Wei Sisi, Han Lina, Guo Zhongyu, Zhao Lianmei, Gao Feng

Source: Open Medicine, Vol 20, Iss 1, Pp 11193-205 (2025)

Subject Terms: p-hydroxyl cinnamaldehyde, cmsp, sclc, mitochondrial dysfunction, ferroptosis, hmox1, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2391-5463

Access URL: https://doaj.org/article/2367d1681ad549cea523407f47681a1e

miR-328-3p suppresses hepatocellular carcinoma progression by regulating HMOX1 expression

Authors: Weixing Wang, Jun Li, Changjun Pan, Deguo Wang, Jian Dong

Source: Discover Oncology, Vol 15, Iss 1, Pp 1-12 (2024)

Subject Terms: Hepatocellular carcinoma, miR-328-3p, HMOX1, Progression, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2730-6011

Access URL: https://doaj.org/article/29b2d802535743eb9a38f6b9dc99fefb

Gut microbiota derived metabolite trimethylamine N-oxide influences prostate cancer progression via the p38/HMOX1 pathway

Authors: Yuhua Zhou, Jing Lv, Shengkai Jin, Chaowei Fu, Bo Liu, Yang Shen, Menglu Li, Yuwei Zhang, Ninghan Feng

Source: Frontiers in Pharmacology, Vol 15 (2025)

Subject Terms: trimethylamine N-oxide, gut microbiota, prostate cancer, HMOX1, high-choline diet, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1526051/full; https://doaj.org/toc/1663-9812

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HMOX1: A pivotal regulator of prognosis and immune dynamics in ovarian cancer

Authors: Jinfa Huang, Ruiwan Tan

Source: BMC Women's Health, Vol 24, Iss 1, Pp 1-15 (2024)

Subject Terms: HMOX1, Ovarian cancer, Immune infiltration, Gynecology and obstetrics, RG1-991, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1472-6874

Access URL: https://doaj.org/article/1666e1db7314450da61547ca94049523

Synthesis and antitumor activity of a novel class of covalent inhibitors of EGFR with 2-indolone backbone

Authors: Tan, Huayuan ^{a, b, 1}, Zhou, Yue ^{b, 1}, Li, Fulian ^b, Xu, Chenlu ^b, Li, Chengpeng ^b, Meng, Jiao ^a, Shao, Lihui ^a, Liu, Bingqian ^b, Chen, Danping ^b, Li, Zhurui ^b, Li, Chenchen ^{b, ⁎}, Wu, Jian ^{a, ⁎}, Wang, Zhenchao ^{a, b, ⁎⁎}

Source: In Bioorganic Chemistry March 2025 156

Bilirubin bioconversion to urobilin in the gut-liver-kidney axis: A biomarker for insulin resistance in the Cardiovascular-Kidney-Metabolic (CKM) Syndrome

Authors: Kipp, Zachary A. ^a, Badmus, Olufunto O. ^b, Stec, David E. ^b, Hall, Brantley ^c, Hinds, Terry D., Jr ^{a, ⁎}

Source: In Metabolism February 2025 163

Spermidine inactivates proteasome activity and enhances ferroptosis in prostate cancer

Authors: Feng, Dan ^a, Zhang, Jian ^b, Niu, Huanmin ^b, Zheng, Xiaoxue ^b, Jia, Mengqi ^b, Lu, Qiqi ^b, Wang, Jing ^b, Guo, Wenxue ^b, Sun, Qi ^b, Yuan, Huiqing ^{b, ⁎}, Lou, Hongxiang ^{a, c, ⁎}

Source: In Acta Pharmaceutica Sinica B December 2024

M2 macrophage derived HMOX1 defines chronic rhinosinusitis with nasal polyps

Authors: Enhao Wang, Yanghe Hao, Jing Song, Jing Yuan, Yu Hong, Ying Li, Yang Wang, Chengshuo Wang, Ming Wang, Luo Zhang

Source: Clinical and Translational Allergy, Vol 14, Iss 12, Pp n/a-n/a (2024)

Subject Terms: CD163, chronic rhinosinusitis with nasal polyps, diagnostic signature, HMOX1, M2 macrophages, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7022

Access URL: https://doaj.org/article/bdf81df919564ccc890289ca9c84e17a

Centipeda minima extract exhibits anti-liver cancer effects via the ER stress/HMOX1/Fe2+/ROS pathway

Authors: Wei, Jinrui ^{b, 1}, Zhao, Xuqi ^{a, 1}, Wu, Baixuan ^{a, 1}, Tan, Zhenkai ^a, Xie, Yuxin ^a, Wei, Mingming ^{c, ⁎}, Wu, Lichuan ^{a, ⁎}

Source: In Phytomedicine April 2025 139

Juglone induces ferroptotic effect on hepatocellular carcinoma and pan-cancer via the FOSL1-HMOX1 axis

Authors: Wang, Chuyu ^{a, 1}, Zhao, Ying ^{a, 1}, Peng, Yingfei ^{a, 1}, Chen, Wei ^a, Zhu, Jie ^a, Gu, Chenzheng ^a, Huo, Ran ^a, Ding, Lin ^a, Liu, Yu ^a, Liu, Te ^e, Zhang, Chunyan ^{a, b, c, d}, Yang, Wenjing ^{a, ⁎}, Wang, Hao ^{a, ⁎}, Guo, Wei ^{a, b, c, d, ⁎}, Wang, Beili ^{a, b, c, d, ⁎}

Source: In Phytomedicine April 2025 139

Association of long non-coding RNAs and ABO blood groups with acute lymphoblastic leukemia in Egyptian children

Authors: Noha H. Sayed, Mahmoud Hammad, Safeya A. Abdelrahman, Hanan M. Abdelgawad

Source: Non-coding RNA Research, Vol 9, Iss 2, Pp 307-317 (2024)

Subject Terms: ABO blood groups, ANRIL, CDKN2A, Childhood ALL, HMOX1, LINC-PINT, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468054024000106; https://doaj.org/toc/2468-0540

Access URL: https://doaj.org/article/5ddc162f11ac4cdfa15a2ab5fbf5e2a3

Pathological significance of heme oxygenase-1 as a potential tumor promoter in heme-induced colorectal carcinogenesis

Authors: Rachitha Singhabahu, Sujani M. Kodagoda Gamage, Vinod Gopalan

Source: Cancer Pathogenesis and Therapy, Vol 2, Iss 2, Pp 65-73 (2024)

Subject Terms: Heme, Carcinogenesis, Colorectal cancer, HMOX1, Promoter, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2949713223000216; https://doaj.org/toc/2949-7132

Access URL: https://doaj.org/article/877f774adf28498fa9c16b1f1e46cf8a

Chronic IL-1-Exposed LNCaP Cells Evolve High Basal p62-KEAP1 Complex Accumulation and NRF2/KEAP1-Dependent and -Independent Hypersensitive Nutrient Deprivation Response

Authors: Haley Dahl-Wilkie, Jessica Gomez, Anastasia Kelley, Kirti Manjit, Basir Mansoor, Preethi Kanumuri, Sammy Pardo, Dana Molleur, Rafah Falah, Anisha R. Konakalla, Morolake Omiyale, Susan Weintraub, Nikki A. Delk

Source: Cells, Vol 14, Iss 3, p 192 (2025)

Subject Terms: chronic IL-1, HMOX1, GCLC, p62-KEAP1, NRF2, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/14/3/192; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/4a99a9ca9b6c4b738cab02c8046fe413

The Plasma-Induced Leukemia Cell Death is Dictated by the ROS Chemistry and the HO-1/CXCL8 Axis

Authors: Bekeschus, S., Clemen, R., Haralambiev, L., Niessner, F., Grabarczyk, P., Weltmann, K., Menz, J., Stope, M., von Woedtke, T., Gandhirajan, R., Schmidt, A.

Source: IEEE Transactions on Radiation and Plasma Medical Sciences IEEE Trans. Radiat. Plasma Med. Sci. Radiation and Plasma Medical Sciences, IEEE Transactions on. 5(3):398-411 May, 2021

Shenqi Sanjie Granules induce Hmox1-mediated ferroptosis to inhibit colorectal cancer

Authors: Meng Chen, Shengli Ma, Wenbo Ji, Weihua Hu, Jiguang Gao, Jianke Yang, Yu Liu, Qianwen Cui, Shasha Yang, Xiaohui Xu, Haiming Dai, Lei Hu

Source: Heliyon, Vol 10, Iss 18, Pp e38021- (2024)

Subject Terms: Chinese herbal medicine, Shenqi Sanjie granules, Hmox1, Ferroptosis, Colorectal cancer, Quercetin, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024140522; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/8e5b7e0ce4b04d5ab78d0c70194e4438

Follicular fluid-derived exosomal HMOX1 promotes granulosa cell ferroptosis involved in follicular atresia in geese (Anser cygnoides)

Authors: Yu Zhang, Youluan Jiang, Xiaoqian Dong, Shuwen Luo, Guoyu Jiao, Kaiqi Weng, Qiang Bao, Yang Zhang, Wanwipa Vongsangnak, Guohong Chen, Qi Xu

Source: Poultry Science, Vol 103, Iss 8, Pp 103912- (2024)

Subject Terms: exosome, HMOX1, follicular granulosa cell, ferroptosis, follicular atresia, Animal culture, SF1-1100

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0032579124004917; https://doaj.org/toc/0032-5791

Access URL: https://doaj.org/article/3deb5e38f8a947fca981f4cc2aa4e614

A non-canonical role of ELN protects from cellular senescence by limiting iron-dependent regulation of gene expression

Authors: Joanna Czarnecka-Herok, Kexin Zhu, Jean-Michel Flaman, Delphine Goehrig, Mathieu Vernier, Gabriela Makulyte, Aline Lamboux, Helena Dragic, Muriel Rhinn, Jean-Jacques Médard, Gilles Faury, Philippe Bertolino, Vincent Balter, Romain Debret, Serge Adnot, Nadine Martin, David Bernard

Source: Redox Biology, Vol 73, Iss , Pp 103204- (2024)

Subject Terms: Cellular senescence, ELN, HMOX1, ROS, Iron, PHF8, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231724001824; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/7802765a7933406fa2443144126cebb7