Meta learning for mutant HLA class I epitope immunogenicity prediction to accelerate cancer clinical immunotherapy.

Authors: Xu, Long¹ (AUTHOR), Yang, Qiang^1,2 (AUTHOR), Dong, Weihe³ (AUTHOR), Li, Xiaokun^1,4,5,6 (AUTHOR), Wang, Kuanquan¹ (AUTHOR), Dong, Suyu³ (AUTHOR), Zhang, Xianyu⁷ (AUTHOR), Yang, Tiansong⁸ (AUTHOR), Luo, Gongning^1,9 (AUTHOR), Liao, Xingyu¹⁰ (AUTHOR), Gao, Xin⁹ (AUTHOR), Wang, Guohua^1,3 (AUTHOR)

Source: Briefings in Bioinformatics. Jan2025, Vol. 26 Issue 1, p1-13. 13p.

Subject Terms: HLA histocompatibility antigens, Immune response, Peptides, Antigen presentation, Cancer vaccines

Gut microbiota, immune cell, colorectal cancer association mediators: a Mendelian randomization study.

Authors: Li, Yuegang¹ (AUTHOR), Zhuang, Meng² (AUTHOR), Mei, Shiwen² (AUTHOR), Hu, Gang² (AUTHOR), Zhang, Jinzhu² (AUTHOR), Qiu, Wenlong² (AUTHOR), Wang, Xishan² (AUTHOR), Tang, Jianqiang² (AUTHOR) doc_tjq@hotmail.com

Source: BMC Cancer. 3/4/2025, Vol. 25 Issue 1, p1-8. 8p.

Subject Terms: *MENDELIAN randomization, *HLA histocompatibility antigens, *GENOME-wide association studies, *COLORECTAL cancer, *BIFIDOBACTERIUM bifidum

Mem-based pangenome indexing for k-mer queries.

Authors: Hwang, Stephen¹ (AUTHOR) shwang45@jh.edu, Brown, Nathaniel K.² (AUTHOR) nbrown99@jh.edu, Ahmed, Omar Y.² (AUTHOR) oahmed6@jh.edu, Jenike, Katharine M.² (AUTHOR) kjenike1@jh.edu, Kovaka, Sam² (AUTHOR) skovaka1@jh.edu, Schatz, Michael C.² (AUTHOR) mschatz@cs.jhu.edu, Langmead, Ben² (AUTHOR) langmea@cs.jhu.edu

Source: Algorithms for Molecular Biology. 3/1/2025, Vol. 20 Issue 1, p1-15. 15p.

Subject Terms: *DE Bruijn graph, *HLA histocompatibility antigens, *COMPARATIVE genomics, *PAN-genome, *MEMORANDUMS

Establishing an HLA-Typed Plateletpheresis Donor Registry at the Iranian Blood Transfusion Organization.

Authors: Sabaghi, Fatemeh^1,2, Shahidi, Minoo¹ shahidi.minoo@gmail.com, Safa, Majid, Faranoush, Mohammad³, Jamali, Mostafa², Salekmoghadam, Ebadollah², Mohamadali, Fatemeh², Sharifi, Shahin², Mohammadi, Saeed⁴, Golestani, Reza²

Source: Iranian Journal of Allergy, Asthma & Immunology. Feb2025, Vol. 24 Issue 1, p52-60. 9p.

Subject Terms: *HISTOCOMPATIBILITY class I antigens, *HLA histocompatibility antigens, *STEM cell donors, *BLOOD platelet transfusion, *CULTURAL pluralism

RNAseq of peripheral blood mononucleated cells exposed to platelet-rich fibrin and enamel matrix derivatives.

Authors: Panahipour, Layla¹ (AUTHOR), Kargarpour, Zahra^1,2 (AUTHOR), Mildner, Michael³ (AUTHOR), Kühtreiber, Hannes³ (AUTHOR), Gruber, Reinhard^1,4,5 (AUTHOR) reinhard.gruber@meduniwien.ac.at

Source: Scientific Reports. 1/29/2025, Vol. 15 Issue 1, p1-13. 13p.

Subject Terms: *HLA histocompatibility antigens, *PLATELET-rich fibrin, *FC receptors, *BLOOD cells, *CALPROTECTIN, *WOUND healing, *CHEMOKINE receptors

The role of human leukocyte antigen in HTLV-1 infection and progression to ATLL and HAM/TSP: a systematic review and meta-analysis.

Authors: Mardi, Shayan¹ (AUTHOR), Rashidian, Maryam² (AUTHOR), Bastan, Fatemeh² (AUTHOR), Molaverdi, Ghazale² (AUTHOR), Mozhgani, Sayed-Hamidreza^3,4 (AUTHOR) hamidrezamozhgani@gmail.com

Source: Virology Journal. 1/20/2025, Vol. 22 Issue 1, p1-15. 15p.

Subject Terms: *HTLV-I, *HLA histocompatibility antigens, *HTLV, *DISEASE progression

Anti-Human Leukocyte Antigen Antibody Detection from Terasaki's Humoral Theory to Delisting Strategies in 2024.

Authors: San Segundo, David^1,2 (AUTHOR) david.sansegundo@scsalud.es, Comins-Boo, Alejandra^1,2 (AUTHOR) alejandra.comins@scsalud.es, López-Hoyos, Marcos^1,2,3 (AUTHOR) marcos.lopez@scsalud.es

Source: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 2, p630. 14p.

Subject Terms: *HLA histocompatibility antigens, *FACIAL transplantation, *ANTIBODY titer, *COMPLEMENT activation, *IMMUNE system

A novel mitochondrial-related risk model for predicting prognosis and immune checkpoint blockade therapy response in uterine corpus endometrial carcinoma.

Authors: Liao, Ru-Gen¹ (AUTHOR), Wang, Jin-Hong² (AUTHOR), Zhang, Fan³ (AUTHOR), Fang, Yu-Tong⁴ (AUTHOR) fyt1996@126.com, Zhou, Li^5,6 (AUTHOR) zlyyzl@126.com, Zhang, Yong-Qu^4,6 (AUTHOR) zhangyq@stu.edu.cn

Source: Scientific Reports. 1/9/2025, Vol. 15 Issue 1, p1-18. 18p.

Subject Terms: *HLA histocompatibility antigens, *DISEASE risk factors, *MEDICAL sciences, *LANDSCAPE assessment, *TREATMENT effectiveness

Learning predictive signatures of HLA type from T-cell repertoires.

Authors: Ruiz Ortega, María¹ (AUTHOR), Pogorelyy, Mikhail V.² (AUTHOR), Minervina, Anastasia A.² (AUTHOR), Thomas, Paul G.² (AUTHOR), Mora, Thierry¹ (AUTHOR) thierry.mora@phys.ens.fr, Walczak, Aleksandra M.¹ (AUTHOR) thierry.mora@phys.ens.fr

Source: PLoS Computational Biology. 1/6/2025, Vol. 21 Issue 1, p1-15. 15p.

Subject Terms: *HLA histocompatibility antigens, *MAJOR histocompatibility complex, *INDIVIDUALIZED medicine, *T cell receptors, *ALLELES, *BLOOD sampling, *T cells

Matched Unrelated Donor Hematopoietic Cell Transplantation: Increased Usage and Improvements in Clinical Outcomes in Canada.

Authors: Seftel, Matthew D.¹ (AUTHOR) david.allan@blood.ca, Musto, Grace² (AUTHOR) obucher@cancercare.mb.ca, Allan, David¹ (AUTHOR), Bucher, Oliver² (AUTHOR), Hay, Kevin³ (AUTHOR) kevin.hay@ucalgary.ca, Pasic, Ivan⁴ (AUTHOR) ivan.pasic@uhn.ca, Truong, Tony⁵ (AUTHOR) tony.truong@albertahealthservices.ca, Paulson, Kristjan⁶ (AUTHOR) kpaulson@cancercare.mb.ca

Source: Current Oncology. Jan2025, Vol. 32 Issue 1, p10. 6p.

Subject Terms: *HEMATOPOIETIC stem cell transplantation, *HLA histocompatibility antigens, *OVERALL survival, *CELLULAR therapy, *MUD

Redosing with Intralymphatic GAD-Alum in the Treatment of Type 1 Diabetes: The DIAGNODE-B Pilot Trial.

Authors: Casas, Rosaura¹ (AUTHOR) rosaura.casas@liu.se, Tompa, Andrea^2,3 (AUTHOR) andrea.tompa@ju.se, Åkesson, Karin⁴ (AUTHOR) karin.akesson@liu.se, Teixeira, Pedro F.⁵ (AUTHOR) pedro.teixeira@diamyd.com, Lindqvist, Anton⁵ (AUTHOR) anton.lindqvist@diamyd.com, Ludvigsson, Johnny^1,6 (AUTHOR) johnny.ludvigsson@liu.se

Source: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 1, p374. 16p.

Subject Terms: *TYPE 1 diabetes, *HLA histocompatibility antigens, *PANCREATIC beta cells, *BETA functions, *INSULIN therapy

Identifying Strong Neoantigen MHC-I/II Binding Candidates for Targeted Immunotherapy with SINE.

Authors: Bendik, Joseph¹ (AUTHOR), Castro, Andrea^1,2 (AUTHOR), Califano, Joseph^1,3,4 (AUTHOR), Carter, Hannah^1,2 (AUTHOR), Guo, Theresa^1,3,4 (AUTHOR) twguo@health.ucsd.edu

Source: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 1, p205. 18p.

Subject Terms: *HEAD & neck cancer, *HLA histocompatibility antigens, *ALTERNATIVE RNA splicing, *MAJOR histocompatibility complex, *SQUAMOUS cell carcinoma, *RNA splicing

Distribution of Major HLA-A, -B, -DR, and -DQ Loci Potentially Associated with Multiple Sclerosis in a Healthy Population from Southern Morocco.

Authors: Fguirouche, Abir^1,2 (AUTHOR) a.fguirouche.ced@uca.ac.ma, Ouahmani, Fatimazahra¹ (AUTHOR) ik.brahim@chumarrakech.ma, Brahim, Ikram¹ (AUTHOR) ra.hazime@uca.ac.ma, Hazime, Raja^1,2 (AUTHOR) br.admou@uca.ac.ma, Louhab, Nissrine³ (AUTHOR) ni.louhab@uca.ma, Kissani, Najib³ (AUTHOR) na.kissani@uca.ma, Chraa, Mohamed³ (AUTHOR) m.chraa@uca.ac.ma, Admou, Brahim^1,2 (AUTHOR)

Source: Clinics & Practice. Jan2025, Vol. 15 Issue 1, p10. 11p.

Subject Terms: *HLA histocompatibility antigens, *MOROCCANS, *MULTIPLE sclerosis, *CYTOTOXINS, *OLIGONUCLEOTIDES

Geographic Terms: MOROCCO

The Promising Effect of Tocilizumab on Chronic Antibody-Mediated Rejection (cAMR) of Kidney Transplant.

Authors: Świątek, Łukasz¹ (AUTHOR) luk.swi@outlook.com, Miedziaszczyk, Miłosz^2,3 (AUTHOR), Lewandowski, Dominik¹ (AUTHOR), Robakowski, Filip¹ (AUTHOR), Tyburski, Piotr¹ (AUTHOR), Jakubowska, Marta¹ (AUTHOR), Karczewski, Marek² (AUTHOR), Idasiak-Piechocka, Ilona² (AUTHOR) ilonaidasiak@poczta.onet.pl

Source: Pharmaceutics. Jan2025, Vol. 17 Issue 1, p78. 13p.

Subject Terms: *HLA histocompatibility antigens, *GRAFT rejection, *KIDNEY transplantation, *TRANSPLANTATION of organs, tissues, etc., *RANDOMIZED controlled trials

Bioinformatic Tools for Studying the Cellular Immune Response to SARS-CoV-2, Vaccine Efficacy, and Future Pandemics at the Global Population Level.

Authors: López, Daniel¹ (AUTHOR) dlopez@isciii.es, Zumárraga, Javier¹ (AUTHOR)

Source: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 24, p13477. 16p.

Subject Terms: *HLA histocompatibility antigens, *VACCINE effectiveness, *IMMUNE response, *CELL analysis, *GENETIC polymorphisms

HLA and Non-HLA Factors for Donor Selection in Hematopoietic Stem Cell Transplantation with Post-Transplant Cyclophosphamide GvHD Prophylaxis.

Authors: Shike, Hiroko¹ (AUTHOR) hshike@pennstatehealth.psu.edu, Zhang, Aiwen² (AUTHOR) zhanga2@ccf.org

Source: Cells (2073-4409). Dec2024, Vol. 13 Issue 24, p2067. 11p.

Subject Terms: *HEMATOPOIETIC stem cell transplantation, *HLA histocompatibility antigens, *STEM cell transplantation, *SURVIVAL rate, *HEMATOLOGIC malignancies

HLA Class I and II Alleles in Anti-Acetylcholine Receptor Antibodies Positive and Double-Seronegative Myasthenia Gravis Patients of Romanian Descent.

Authors: Croitoru, Cristina Georgiana^1,2 (AUTHOR), Constantinescu, Daniela^2,3 (AUTHOR), Pavel-Tanasa, Mariana^2,3 (AUTHOR), Cuciureanu, Dan Iulian^1,4 (AUTHOR), Cianga, Corina Maria^2,3 (AUTHOR), Hodorog, Diana Nicoleta^1,4 (AUTHOR), Cianga, Petru^2,3 (AUTHOR) petru.cianga@umfiasi.ro

Source: Neurology International. Dec2024, Vol. 16 Issue 6, p1819-1836. 18p.

Subject Terms: *HLA histocompatibility antigens, *MYASTHENIA gravis, *RECEPTOR antibodies, *NUCLEOTIDE sequencing, *GENE frequency

Features of Highly Homologous T-Cell Receptor Repertoire in the Immune Response to Mutations in Immunogenic Epitopes.

Authors: Zornikova, Ksenia¹ (AUTHOR) kvzornikova@gmail.com, Dianov, Dmitry¹ (AUTHOR), Ivanova, Natalia¹ (AUTHOR), Davydova, Vassa¹ (AUTHOR), Nenasheva, Tatiana¹ (AUTHOR), Fefelova, Ekaterina¹ (AUTHOR), Bogolyubova, Apollinariya¹ (AUTHOR) apollinariya.bogolyubova@gmail.com

Source: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 23, p12591. 16p.

Subject Terms: *HLA histocompatibility antigens, *COVID-19 pandemic, *COVID-19, *SARS-CoV-2, *IMMUNOLOGIC memory

Future directions in haploidentical hematopoietic stem cell transplantation.

Authors: Vittayawacharin, Pongthep^1,2 (AUTHOR), Kongtim, Piyanuch¹ (AUTHOR), Ciurea, Stefan O.¹ (AUTHOR) sciurea@hs.uci.edu

Source: Hematology. Dec2024, Vol. 29 Issue 1, p1-8. 8p.

Subject Terms: *HLA histocompatibility antigens, *KILLER cells, *HEMATOPOIETIC stem cell transplantation, *CHIMERIC antigen receptors, *CELLULAR therapy, *GRAFT versus host disease, *STEM cell transplantation

B2M or CIITA knockdown decreased the alloimmune response of dental pulp stem cells: an in vitro study.

Authors: Hu, Mingxin¹ (AUTHOR), Zhang, Yuchen² (AUTHOR), Liu, Junqing¹ (AUTHOR), Chen, Yihan¹ (AUTHOR), Kang, Jun¹ (AUTHOR), Zhong, Jialin¹ (AUTHOR), Lin, Shulan¹ (AUTHOR), Liang, Ye¹ (AUTHOR), Cen, Rong¹ (AUTHOR), Zhu, Xiaofei³ (AUTHOR), Zhang, Chengfei¹ (AUTHOR) zhangcf@hku.hk

Source: Stem Cell Research & Therapy. 11/14/2024, Vol. 15 Issue 1, p1-18. 18p.

Subject Terms: *HLA histocompatibility antigens, *MAJOR histocompatibility complex, *DENTAL pulp, *HUMAN stem cells, *CLINICAL medicine