Conformational antigenic heterogeneity as a cause of the persistent fraction in HIV-1 neutralization

Authors: Philippe Colin, Rajesh P. Ringe, Anila Yasmeen, Gabriel Ozorowski, Thomas J. Ketas, Wen-Hsin Lee, Andrew B. Ward, John P. Moore, P. J. Klasse

Source: Retrovirology, Vol 20, Iss 1, Pp 1-20 (2023)

Subject Terms: HIV-1 neutralization, Broadly active neutralizing antibodies (bNAbs), Persistent fraction, Efficacy, Antigenic heterogeneity, Stoichiometry, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1742-4690

Access URL: https://doaj.org/article/f369c2c702f8496ebac50311e4de718b

A lentiviral vector B cell gene therapy platform for the delivery of the anti-HIV-1 eCD4-Ig-knob-in-hole-reversed immunoadhesin

Authors: Eirini Vamva, Stosh Ozog, Daniel P. Leaman, Rene Yu-Hong Cheng, Nicholas J. Irons, Andee Ott, Claire Stoffers, Iram Khan, Geraldine K.E. Goebrecht, Matthew R. Gardner, Michael Farzan, David J. Rawlings, Michael B. Zwick, Richard G. James, Bruce E. Torbett

Source: Molecular Therapy: Methods & Clinical Development, Vol 28, Iss , Pp 366-384 (2023)

Subject Terms: HIV-1 neutralization, lentiviral, immunoadhesin, eCD4-Ig, protein engineering, hematopoietic, Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050123000141; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/5335a8f9645a42be9c9d7d049a240b62

The CCR5 Receptor Acts as an Alloantigen in CCR5Δ 32 Homozygous Individuals: Identification of Chemokine-and HIV-1-Blocking Human Antibodies

Authors: Ditzel, Henrik J., Rosenkilde, Mette M., Garred, Peter, Wang, Meng, Koefoed, Klaus, Pedersen, Court, Burton, Dennis R., Schwartz, Thue W.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1998 Apr . 95(9), 5241-5245.

Access URL: https://www.jstor.org/stable/44698

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