Signal detection and safety analysis of three tyrosine kinase inhibitors for HER-2 positive breast cancer: a retrospective study based on the FAERS database

Authors: Xiting Tang, Chengliang Wang, Yanwei Li, Jing Tang, Guoping Zhang, Li Chen

Source: Frontiers in Pharmacology, Vol 16 (2025)

Subject Terms: FAERS database, tyrosine kinase inhibitors (TKIs), HER-2 positive breast cancer, adverse event signals, safety analysis, disproportionality analysis (ROR, PRR), Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2025.1538881/full; https://doaj.org/toc/1663-9812

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A rare case of intracystic Her-2 positive young breast cancer

Authors: Jia, Xiaochen, Meng, Wenjing, Li, Shufen, Tong, Zhongsheng, Jia, Yongsheng

Source: 2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) Bioinformatics and Biomedicine (BIBM), 2021 IEEE International Conference on. :2598-2602 Dec, 2021

Relation: 2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

Severe Thrombocytopenia from Trastuzumab and Pertuzumab Combination Therapy in a Patient with HER2-Positive Metastatic Rectal Cancer

Authors: Dai Okemoto, Toshifumi Yamaguchi, Mariko Yamaguchi, Toru Kadono, Hiroki Yukami, Elham Fakhrejahani, Hiroki Nishikawa

Source: Case Reports in Oncology, Vol 17, Iss 1, Pp 1001-1007 (2024)

Subject Terms: thrombocytopenia, trastuzumab and pertuzumab, her-2 positive rectal cancer, eltrombopag, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://beta.karger.com/Article/FullText/540980; https://doaj.org/toc/1662-6575

Access URL: https://doaj.org/article/1642784669d742c396cf1d2633a51794

Ultrasound-triggered topical oxygen delivery enhances synergistic sonodynamic and antibody therapies against hypoxic gastric cancer

Authors: Xie, Xinxin ^{a, b, 1}, Zhang, Jinxia ^{a, 1}, Sun, Lihong ^{a, 1}, Xu, Shuyu ^a, Ma, Shiti Sha ^a, Wang, Haonan ^a, Li, Xiaoda ^c, Xiang, Qiong ^d, Cui, Ligang ^{a, ⁎}, Liang, Xiaolong ^{a, b, ⁎}

Source: In Journal of Controlled Release 10 April 2025 380:736-750

Intracranial management of HER-2 overexpression breast cancer with extensive volume or symptomatic brain metastases

Authors: Juan Li, Junjie Zhen, Ruyu Ai, Mingyao Lai, Hui Wang, Linbo Cai

Source: Frontiers in Oncology, Vol 14 (2024)

Subject Terms: breast cancer, brain metastasis, HER-2 positive, radiotherapy, targeted drug, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1386909/full; https://doaj.org/toc/2234-943X

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Pyrotinib-based therapeutic approaches for HER2-positive breast cancer: the time is now

Authors: Xiaowei Qi, Qiyun Shi, Juncheng Xuhong, Yi Zhang, Jun Jiang

Source: Breast Cancer Research, Vol 25, Iss 1, Pp 1-11 (2023)

Subject Terms: Pyrotinib, HER-2 positive, Breast cancer, Targeted therapy, Tyrosine-kinase inhibitor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1465-542X

Access URL: https://doaj.org/article/c29fc4d05fb3411cb15ea3610109f2ec

Effects of Different Neoadjuvant Chemotherapy Regimens on Immune Indicators and Tumor Microenvironment in HER-2-positive Breast Cancer Patients

Authors: PEI Bei, CHENG Lin, XU Lingyun

Source: Zhongguo quanke yixue, Vol 26, Iss 27, Pp 3435-3440 (2023)

Subject Terms: breast neoplasms, her-2 positive, antineoplastic combined chemotherapy protocols, molecular targeted therapy, double target therapy, tumor microenvironment, immune index, Medicine

File Description: electronic resource

Relation: https://www.chinagp.net/fileup/1007-9572/PDF/1687830841493-24201144.pdf; https://doaj.org/toc/1007-9572

Access URL: https://doaj.org/article/a310c076ea734416919efc45bcb68486

A case of HER-2 positive breast metaplastic carcinoma: The medium-highly differentiated squamous cell carcinoma

Authors: Yaning Li, Guoyu Song, Hang Su, Fenghua Zhang

Source: Asian Journal of Surgery, Vol 47, Iss 5, Pp 2548-2549 (2024)

Subject Terms: Breast metaplastic carcinoma, Squamous cell carcinoma of breast, HER-2 positive breast metaplastic carcinoma, Surgery, RD1-811

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1015958424003178; https://doaj.org/toc/1015-9584

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Bilateral inflammatory recurrence of HER-2 positive breast cancer: a unique case report and literature review

Authors: Rong Qin, Xiangyang Wang, Tingting Fan, Ting Wu, Chao Lu, Xun Shao, Liang Yin

Source: Frontiers in Oncology, Vol 14 (2024)

Subject Terms: inflammatory breast cancer, bilateral recurrence, HER-2 positive breast cancer, case report, whole-exome sequencing, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1276637/full; https://doaj.org/toc/2234-943X

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Integrated pancancer analysis reveals the oncogene characteristics and prognostic value of DIP2B in breast cancer

Authors: Chengyang Song, Fangjian Shang, Wei Tu, Xiaodan Liu

Source: BMC Cancer, Vol 23, Iss 1, Pp 1-20 (2023)

Subject Terms: DIP2B, Oncogene, Pancancer, Breast cancer, Her-2 positive, Prognosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/00a1da877f454dc8bacdb89fb78bcdbf

Pathologic response and survival after neoadjuvant chemotherapy with or without pertuzumab in patients with HER2-positive breast cancer: the Neopearl nationwide collaborative study

Authors: Agnese Fabbri, Fabrizio Nelli, Andrea Botticelli, Diana Giannarelli, Eleonora Marrucci, Cristina Fiore, Antonella Virtuoso, Simone Scagnoli, Simona Pisegna, Daniele Alesini, Valentina Sini, Armando Orlandi, Alessandra Fabi, Federico Piacentini, Luca Moscetti, Giuliana D’Auria, Teresa Gamucci, Marco Mazzotta, Laura Pizzuti, Patrizia Vici, Elisabetta Cretella, Paola Scavina, Annalisa La Cesa, Mara Persano, Francesco Atzori, Enzo Maria Ruggeri

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: pertuzumab, trastuzumab, breast cancer, neoadjuvant chemotherapy, HER-2 positive, real-world data, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1177681/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/26649e667aa0456fbd64724a36c65d33

Corrigendum: HER-2 positive primary neuroendocrine neoplasms of the breast with signet ring feature: A case report and review of literature

Authors: Yunjin Li, Yi Cao, Xiaoying Wu, Ruijie Liu, Kuansong Wang

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: neuroendocrine neoplasm, signet ring feature, breast cancer, HER-2 positive, review, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1154441/full; https://doaj.org/toc/2234-943X

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Focusing on NK cells and ADCC: A promising immunotherapy approach in targeted therapy for HER2-positive breast cancer

Authors: Feifei Li, Sheng Liu

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: HER-2 positive breast cancer, NK cells, ADCC, immunotherapy approach, monoclonal antibodies, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1083462/full; https://doaj.org/toc/1664-3224

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Patients with positive HER-2 amplification advanced gastroesophageal junction cancer achieved complete response with combined chemotherapy of AK104/cadonilimab (PD-1/CTLA-4 bispecific): A case report

Authors: Jieqiong Peng, Qiang Zhu, Ziru Peng, Zhen Chen, Yuantao Liu, Bo Liu

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: PD-1/CTLA-4 bispecific, AK104/cadonilimab, HER-2 positive, complete response, advanced gastroesophageal junction cancer, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1049518/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3a9480665b894f07bce39acb264827e9

HER-2-positive primary neuroendocrine neoplasms of the breast with signet ring feature: A case report and review of literature

Authors: Yunjin Li, Yi Cao, Xiaoying Wu, Ruijie Liu, Kuansong Wang

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: neuroendocrine neoplasm, signet ring feature, breast cancer, HER-2 positive, review, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.1029007/full; https://doaj.org/toc/2234-943X

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Metronomic oral chemotherapy with cyclophosphamide plus capecitabine combined with trastuzumab (HEX) as first line therapy of HER-2 positive advanced breast cancer: A phase II trial of the Gruppo Oncologico Italia Meridionale (GOIM)

Authors: Laura Orlando, Vito Lorusso, Francesco Giotta, Massimo Di Maio, Paola Schiavone, Palma Fedele, Annamaria Quaranta, Chiara Caliolo, Mariangela Ciccarese, Margherita Cinefra, Sante Romito, Salvatore Pisconti, Salvatore del Prete, Michele Aieta, Daniele Rizzi, Evaristo Maiello, Giuseppe Colucci, Saverio Cinieri

Source: Breast, Vol 53, Iss , Pp 18-22 (2020)

Subject Terms: HER-2 positive, Metronomic chemotherapy, Advanced breast cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0960977620301223; https://doaj.org/toc/1532-3080

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Eradication of Stage IV Gastric Cancer: Case Report

Authors: Ibrahim Mohammed, Cherishma Nagisetty, Arslan Iqbal, Michael Abdelmasseh, Doreen Griswold, Muhammad Omer Jamil, Juan R. Sanabria

Source: Marshall Journal of Medicine, Vol 6, Iss 3, Pp 15-19 (2020)

Subject Terms: gastric cancer, surgical resection, her-2 positive, chemotherapy, adenocarcinoma, Medicine (General), R5-920

File Description: electronic resource

Relation: https://mds.marshall.edu/cgi/viewcontent.cgi?article=1259&context=mjm; https://doaj.org/toc/2379-9536

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Discovery of Pyrimidine- and Coumarin-Linked Hybrid Molecules as Inducers of JNK Phosphorylation through ROS Generation in Breast Cancer Cells

Authors: Na Young Kim, Divakar Vishwanath, Zhang Xi, Omantheswara Nagaraja, Ananda Swamynayaka, Keshav Kumar Harish, Shreeja Basappa, Mahendra Madegowda, Vijay Pandey, Gautam Sethi, Peter E. Lobie, Kwang Seok Ahn, Basappa Basappa

Source: Molecules, Vol 28, Iss 8, p 3450 (2023)

Subject Terms: JNK signaling, pyrimidine, coumarin, HER-2 positive breast cancer, apoptosis, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/8/3450; https://doaj.org/toc/1420-3049

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Association of HER-2/CEP17 Ratio and HER-2 Copy Number With pCR Rate in HER-2-Positive Breast Cancer After Dual-Target Neoadjuvant Therapy With Trastuzumab and Pertuzumab

Authors: Fanfan Li, Qian Ju, Cong Gao, Jingjing Li, Xiaolei Wang, Min Yan, Liying Zhang, Meiling Huang, Qihe Long, Xiangting Jin, Nanlin Li

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: breast cancer, HER-2 positive, IHC, FISH, dual-target neoadjuvant therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.819818/full; https://doaj.org/toc/2234-943X

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A high absolute lymphocyte count predicts a poor prognosis in HER-2- positive breast cancer patients treated with trastuzumab

Authors: Hong J, Chen X, Gao W, Zhu S, Wu J, Huang O, He J, Zhu L, Chen W, Li Y, Fei X, Lin L, Shen K

Source: Cancer Management and Research, Vol Volume 11, Pp 3371-3379 (2019)

Subject Terms: Breast cancer, HER-2 positive, Trastuzumab, Neutrophil to lymphocyte ratio, Prognosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.dovepress.com/a-high-absolute-lymphocyte-count-predicts-a-poor-prognosis-in-her-2--p-peer-reviewed-article-CMAR; https://doaj.org/toc/1179-1322

Access URL: https://doaj.org/article/c4a94bcb5c5b439ab9339977ffb83aa7