Histone lactylation drives liver cancer metastasis by facilitating NSF1-mediated ferroptosis resistance after microwave ablation

Authors: Jiayan Huang, Huijing Xie, Ju Li, Xiaotong Huang, Yunshi Cai, Rui Yang, Dongmei Yang, Wuyongga Bao, Yongjie Zhou, Tao Li, Qiang Lu

Source: Redox Biology, Vol 81, Iss , Pp 103553- (2025)

Subject Terms: Hepatocellular carcinoma, Thermal ablation, H3K18la, NFS1, Oxaliplatin, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231725000667; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/0bf48918fe7640c7bfda41ed02c7eb4d

Histone lactylation regulates PRKN-Mediated mitophagy to promote M2 Macrophage polarization in bladder cancer

Authors: Deng, Xiaolin ^{a, 1}, Huang, Yuan ^{a, 1}, Zhang, Jinge ^{a, 1}, Chen, Yuwen ^a, Jiang, Feifan ^a, Zhang, Zicai ^a, Li, Tanghua ^a, Hou, Lina ^{b, ⁎}, Tan, Wanlong ^{a, ⁎}, Li, Fei ^{a, ⁎}

Source: In International Immunopharmacology 20 February 2025 148

Effective-compounds of Jinshui Huanxian Formula acts as an SRC inhibitor to inhibit HK2-mediated H3K18 lactation and improve pulmonary fibrosis

Authors: Zheng, Jiaping ^{a, b, 1}, Du, Yan ^{a, b, c, 1}, Shao, Wenbo ^{a, b}, Li, Jiansheng ^{a, b, c, d}, Zhao, Peng ^{a, b, c, ⁎}, Zhang, Qin ^{a, b, c, ⁎}

Source: In Phytomedicine May 2025 140

Positive feedback regulation between glycolysis and histone lactylation drives oncogenesis in pancreatic ductal adenocarcinoma

Authors: Fei Li, Wenzhe Si, Li Xia, Deshan Yin, Tianjiao Wei, Ming Tao, Xiaona Cui, Jin Yang, Tianpei Hong, Rui Wei

Source: Molecular Cancer, Vol 23, Iss 1, Pp 1-24 (2024)

Subject Terms: Glycolysis, Histone lactylation, H3K18la, Pancreatic ductal adenocarcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/9d396e035776494eb85fe93d3a1b67c3

H3K18 lactylation marks tissue-specific active enhancers

Authors: Eva Galle, Chee-Wai Wong, Adhideb Ghosh, Thibaut Desgeorges, Kate Melrose, Laura C. Hinte, Daniel Castellano-Castillo, Magdalena Engl, Joao Agostinho de Sousa, Francisco Javier Ruiz-Ojeda, Katrien De Bock, Jonatan R. Ruiz, Ferdinand von Meyenn

Source: Genome Biology, Vol 23, Iss 1, Pp 1-28 (2022)

Subject Terms: Lactylation, H3K18la, Lactate, Epigenetics, Embryonic stem cell, Muscle, Biology (General), QH301-705.5, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1474-760X

Access URL: https://doaj.org/article/c9ecdc1a92de4e0786206a8879e43b67

Salvianolic Acid B Alleviates Liver Injury by Regulating Lactate-Mediated Histone Lactylation in Macrophages

Authors: Shian Hu, Zehua Yang, Ling Li, Qinwen Yan, Yutong Hu, Feng Zhou, Yang Tan, Gang Pei

Source: Molecules, Vol 29, Iss 1, p 236 (2024)

Subject Terms: macrophages, salvianolic acid B, LDHA, histone lactylation, H3K18la, liver injury, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/29/1/236; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/a38783f4a8764f21ab3f4c3abadfd1f1

Hypoxic in vitro culture reduces histone lactylation and impairs pre-implantation embryonic development in mice

Authors: Wanting Yang, Peijun Wang, Pengbo Cao, Shuang Wang, Yuxiao Yang, Huimin Su, Buhe Nashun

Source: Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-15 (2021)

Subject Terms: Histone lactylation, H3K23la, H3K18la, Oxygen, Hypoxia, Pre-implantation embryo, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-8935

Access URL: https://doaj.org/article/b702d2f5d70b4286a662a08f4a46fac1