Quantitative Multiplexed Analysis of Indoleamine 2,3-Dioxygenase (IDO) and Arginase-1 (ARG1) Expression and Myeloid Cell Infiltration in Colorectal Cancer

Authors: Elomaa, Hanna ^{a, b}, Härkönen, Jouni ^{c, d}, Väyrynen, Sara A. ^e, Ahtiainen, Maarit ^c, Ogino, Shuji ^{f, g, h, i}, Nowak, Jonathan A. ^f, Lau, Mai Chan ^{j, k}, Helminen, Olli ^l, Wirta, Erkki-Ville ^{m, n}, Seppälä, Toni T. ^{n, o, p, q}, Böhm, Jan ^c, Mecklin, Jukka-Pekka ^{b, r}, Kuopio, Teijo ^{a, c}, Väyrynen, Juha P. ^{l, ∗}

Source: In Modern Pathology April 2024 37(4)

Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells

Authors: Deen, Ashik Jawahar, Adinolfi, Simone, Härkönen, Jouni, Patinen, Tommi, Liu, Xiaonan, Laitinen, Tuomo, Takabe, Piia, Kainulainen, Kirsi, Pasonen-Seppänen, Sanna, Gawriyski, Lisa M., Arasu, Uma Thanigai, Selvarajan, Ilakya, Mäkinen, Petri, Laitinen, Hanna, Kansanen, Emilia, Kaikkonen, Minna U., Poso, Antti, Varjosalo, Markku, Levonen, Anna-Liisa

Source: In Redox Biology February 2024 69

The KEAP1-NRF2 pathway: Targets for therapy and role in cancer

Authors: Adinolfi, Simone, Patinen, Tommi, Jawahar Deen, Ashik, Pitkänen, Sini, Härkönen, Jouni, Kansanen, Emilia, Küblbeck, Jenni, Levonen, Anna-Liisa

Source: In Redox Biology July 2023 63

A pan-cancer analysis shows immunoevasive characteristics in NRF2 hyperactive squamous malignancies

Authors: Härkönen, Jouni, Pölönen, Petri, Deen, Ashik Jawahar, Selvarajan, Ilakya, Teppo, Hanna-Riikka, Dimova, Elitsa Y., Kietzmann, Thomas, Ahtiainen, Maarit, Väyrynen, Juha P., Väyrynen, Sara A., Elomaa, Hanna, Tynkkynen, Niko, Eklund, Tiia, Kuopio, Teijo, Talvitie, Eva-Maria, Taimen, Pekka, Kallajoki, Markku, Kaikkonen, Minna U., Heinäniemi, Merja, Levonen, Anna-Liisa

Source: In Redox Biology May 2023 61

Regulation of stress signaling pathways by protein lipoxidation

Authors: Patinen, Tommi, Adinolfi, Simone, Cortés, Carlos Cruz, Härkönen, Jouni, Jawahar Deen, Ashik, Levonen, Anna-Liisa

Source: In Redox Biology May 2019 23

Regulation of stress signaling pathways by nitro-fatty acids

Authors: Deen, Ashik Jawahar, Sihvola, Virve, Härkönen, Jouni, Patinen, Tommi, Adinolfi, Simone, Levonen, Anna-Liisa

Source: In Nitric Oxide 1 August 2018 78:170-175

A novel uterine leiomyoma subtype exhibits NRF2 activation and mutations in genes associated with neddylation of the Cullin 3-RING E3 ligase.

Authors: Mehine, Miika, Ahvenainen, Terhi, Khamaiseh, Sara, Härkönen, Jouni, Reinikka, Siiri, Heikkinen, Tuomas, Äyräväinen, Anna, Pakarinen, Päivi, Härkki, Päivi, Pasanen, Annukka, Levonen, Anna-Liisa, Bützow, Ralf, Vahteristo, Pia

Source: Oncogenesis; 9/7/2022, Vol. 11 Issue 1, p1-10, 10p

Single-Cell Functional Genomics of Natural Killer Cell Interaction with Blood Cancers

Authors: Dufva, Olli ^*, Gandolfi, Sara ^*, Huuhtanen, Jani ^*, Dashevsky, Olga ^*, Saeed, Khalid ^*, Klievink, Jay ^*, Nygren, Petra Johanna ^*, Bouhlal, Jonas ^*, Lahtela, Jenni ^*, Näätänen, Anna ^*, Ghimire, Bishwa ^*, Hannunen, Tiina ^*, Ellonen, Pekka ^*, Duàn, Hanna ^*, Theodoropoulos, Jason ^*, Laajala, Essi ^*, Häkkinen, Aino ^*, Härkönen, Jouni ^*, Pölönen, Petri, Heinäniemi, Merja ^*, Yamano, Shizuka ^*, Shirasaki, Ryosuke ^*, Barbie, David ^*, Roth, Jennifer A. ^*, Romee, Rizwan, Sheffer, Michal ^*, Lähdesmäki, Harri ^*, Lee, Dean Anthony, De Matos Simoes, Ricardo ^*, Kankainen, Matti ^*, Mitsiades, Constantine S., Mustjoki, Satu

Source: In Blood 15 November 2022 140 Supplement 1:8343-8344

Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers.

Authors: Dufva, Olli^1,2,3 (AUTHOR), Gandolfi, Sara^1,2,3,4,5 (AUTHOR), Huuhtanen, Jani^1,2,3,6 (AUTHOR), Dashevsky, Olga^1,4,5,7,8 (AUTHOR), Duàn, Hanna^1,2,3 (AUTHOR), Saeed, Khalid^1,2 (AUTHOR), Klievink, Jay^1,2,3 (AUTHOR), Nygren, Petra^1,2,3 (AUTHOR), Bouhlal, Jonas^1,2,3 (AUTHOR), Lahtela, Jenni⁹ (AUTHOR), Näätänen, Anna⁹ (AUTHOR), Ghimire, Bishwa R.⁹ (AUTHOR), Hannunen, Tiina⁹ (AUTHOR), Ellonen, Pekka⁹ (AUTHOR), Lähteenmäki, Hanna^1,2 (AUTHOR), Rumm, Pauliina^1,2 (AUTHOR), Theodoropoulos, Jason^1,2 (AUTHOR), Laajala, Essi^1,2,3 (AUTHOR), Härkönen, Jouni¹⁰ (AUTHOR), Pölönen, Petri¹¹ (AUTHOR)

Source: Immunity (10747613). Dec2023, Vol. 56 Issue 12, p2816-2816. 1p.

Subject Terms: *FUNCTIONAL genomics, *KILLER cells, *NATURAL immunity, *BLOOD cells, *CANCER cells, *CELL death, *TUMOR suppressor genes