Simultaneous detection of eight cancer types using a multiplex droplet digital PCR assay

Authors: Isabelle Neefs, Nele De Meulenaere, Thomas Vanpoucke, Janah Vandenhoeck, Dieter Peeters, Marc Peeters, Guy Van Camp, Ken Op de Beeck

Source: Molecular Oncology, Vol 19, Iss 1, Pp 188-203 (2025)

Subject Terms: biomarkers, ddPCR, DNA methylation, multi‐cancer detection, multiplexing, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/f79bf26df1f64f20ae9d210da2e502e4

Genome-wide DNA methylation analysis reveals a unique methylation pattern for pleural mesothelioma compared to healthy pleura and other lung diseases

Authors: Janah Vandenhoeck, Joe Ibrahim, Nele De Meulenaere, Dieter Peeters, Jo Raskin, Jeroen M. H. Hendriks, Paul Van Schil, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck

Source: Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)

Subject Terms: Epigenetics, DNA methylation, Pleural mesothelioma, Lung cancer, Healthy pleura, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/af16fa6948c043a6a1663eb565744f43

Transcriptomic analysis of ROS1+ non-small cell lung cancer reveals an upregulation of nucleotide synthesis and cell adhesion pathways

Authors: Marc Terrones, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer, Ligia Mateiu

Source: Frontiers in Oncology, Vol 14 (2024)

Subject Terms: ROS1+ NSCLC, RNA-sequencing, gene co-expression, nucleotide synthesis, cell adhesion, prognostic biomarker, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1408697/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/637c8e9766304bc6b3531fafa69882fb

Clinicopathological and molecular differences between stage IV screen-detected and interval colorectal cancers in the Flemish screening program

Authors: Isabelle Neefs, Thuy Ngan Tran, Allegra Ferrari, Sharon Janssens, Koen Van Herck, Ken Op de Beeck, Guy Van Camp, Marc Peeters, Erik Fransen, Sarah Hoeck, Guido Van Hal

Source: Frontiers in Oncology, Vol 14 (2024)

Subject Terms: colorectal cancer, clinicopathological differences, interval cancer, molecular alterations, screening, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1409196/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/6553165151cc4e56920d8a1a41ed2826

CRISPR/Cas9-edited ROS1 + non-small cell lung cancer cell lines highlight differential drug sensitivity in 2D vs 3D cultures while reflecting established resistance profiles

Authors: Marc Terrones, Christophe Deben, Felicia Rodrigues-Fortes, Anne Schepers, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer

Source: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)

Subject Terms: ROS1 + Non-small cell lung cancer, Tyrosine kinase inhibitors, CRISPR/Cas9, Drug resistance, 3D cell culture, 2D cell culture, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/8badfa4b346b46089af6735007b9b043

Epigenome-wide methylation analysis of colorectal carcinoma, adenoma and normal tissue reveals novel biomarkers addressing unmet clinical needs

Authors: Katleen Janssens, Isabelle Neefs, Joe Ibrahim, Anne Schepers, Patrick Pauwels, Marc Peeters, Guy Van Camp, Ken Op de Beeck

Source: Clinical Epigenetics, Vol 15, Iss 1, Pp 1-14 (2023)

Subject Terms: Colorectal cancer, Methylation, Biomarkers, Adenoma, Carcinoma, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/f0195dd157dc48ceb7a73e17eb3bb1f3

Genetic Evaluation of Prelingual Hearing Impairment: Recommendations of an European Network for Genetic Hearing Impairment

Authors: Laurence Jonard, Davide Brotto, Miguel A. Moreno-Pelayo, Ignacio del Castillo, Hannie Kremer, Ronald Pennings, Helena Caria, Graça Fialho, An Boudewyns, Guy Van Camp, Monika Ołdak, Dominika Oziębło, Naïma Deggouj, Romolo Daniele De Siati, Paolo Gasparini, Giorgia Girotto, Margriet Verstreken, Silvia Dossena, Sebastian Roesch, Saba Battelino, Katarina Trebušak Podkrajšek, Athanasia Warnecke, Thomas Lenarz, Anke Lesinski-Schiedat, Michel Mondain, Anne-Françoise Roux, Françoise Denoyelle, Natalie Loundon, Margaux Serey Gaut, Patrizia Trevisi, Elisa Rubinato, Alessandro Martini, Sandrine Marlin

Source: Audiology Research, Vol 13, Iss 3, Pp 341-346 (2023)

Subject Terms: n/a, Otorhinolaryngology, RF1-547

File Description: electronic resource

Relation: https://www.mdpi.com/2039-4349/13/3/29; https://doaj.org/toc/2039-4349

Access URL: https://doaj.org/article/1f272fa0e4ba4f1d9885851b72d3604b

Widely Split P Waves After Pharmacologic Cardioversion in a Patient With Atrial Fibrillation

Authors: Monika I. Shumkova, MD, PhD, Elayne K. de Oliveira, MD, Dario T. Bertolone, MD, Chiara Valeriano, MD, Isabelle Depoot, MD, Flore Vincent, MD, PhD, Tom De Potter, MD, Guy Van Camp, MD, PhD

Source: JACC: Case Reports, Vol 25, Iss , Pp 102036- (2023)

Subject Terms: atrial tachycardia, echocardiography, electrocardiogram, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666084923003704; https://doaj.org/toc/2666-0849

Access URL: https://doaj.org/article/bd217070d5a440e39811168b9141ca68

Blood transcriptomics to facilitate diagnosis and stratification in pediatric rheumatic diseases – a proof of concept study

Authors: My Kieu Ha, Esther Bartholomeus, Luc Van Os, Julie Dandelooy, Julie Leysen, Olivier Aerts, Vasiliki Siozopoulou, Eline De Smet, Jan Gielen, Khadija Guerti, Michel De Maeseneer, Nele Herregods, Bouchra Lechkar, Ruth Wittoek, Elke Geens, Laura Claes, Mahmoud Zaqout, Wendy Dewals, Annelies Lemay, David Tuerlinckx, David Weynants, Koen Vanlede, Gerlant van Berlaer, Marc Raes, Helene Verhelst, Tine Boiy, Pierre Van Damme, Anna C. Jansen, Marije Meuwissen, Vito Sabato, Guy Van Camp, Arvid Suls, Jutte Van der Werff ten Bosch, Joke Dehoorne, Rik Joos, Kris Laukens, Pieter Meysman, Benson Ogunjimi

Source: Pediatric Rheumatology Online Journal, Vol 20, Iss 1, Pp 1-10 (2022)

Subject Terms: Pediatric rheumatic diseases, RNA sequencing, Blood transcriptomics, Classification model, Pediatrics, RJ1-570, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1546-0096

Access URL: https://doaj.org/article/ae24e919db6f48029c4bfddf7ebc815c

Pathogenic Variants in the COCH Gene That Lead to Hearing Loss and Vestibular Deficit: Update on DFNA9 and Introducing DFNB110

Authors: Vincent Van Rompaey, Hanne Gommeren, Joyce Bosmans, Dorien Verdoodt, Sebastien JanssensdeVarebeke, Erik de Vrieze, Ronald Pennings, Raymond Van de Berg, Marc Lammers, Olivier Vanderveken, Erik Fransen, Guy Van Camp, Erwin Van Wijk

Source: B-ENT, Vol 18, Iss 4, Pp 273-283 (2022)

Subject Terms: Otorhinolaryngology, RF1-547

File Description: electronic resource

Relation: http://www.b-ent.be/en/pathogenic-variants-in-the-coch-gene-that-lead-to-hearing-loss-and-vestibular-deficit-update-on-dfna9-and-introducing-dfnb110-131079; https://doaj.org/toc/2684-4907

Access URL: https://doaj.org/article/2cb1c3d5a66a48399ec0d0f621b0140d

Contemporary European practice in transcatheter aortic valve implantation: results from the 2022 European TAVI Pathway Registry

Authors: Liesbeth Rosseel, Darren Mylotte, Bernard Cosyns, Maarten Vanhaverbeke, David Zweiker, Rui Campante Teles, Oskar Angerås, Antoinette Neylon, Tanja Katharina Rudolph, Joanna J. Wykrzykowska, Tiffany Patterson, Giulia Costa, Soledad Ojeda, Apostolos Tzikas, Marcel Abras, Lionel Leroux, Eric Van Belle, Didier Tchétché, Sabine Bleiziffer, Martin J. Swaans, Radoslaw Parma, Daniel J. Blackman, Nicolas M. Van Mieghem, Marek Grygier, Simon Redwood, Bernard Prendergast, Guy Van Camp, Ole De Backer

Source: Frontiers in Cardiovascular Medicine, Vol 10 (2023)

Subject Terms: Transcatheter aortic valve implantation, aortic stenosis, multidisciplinary Heart Team, minimalist TAVI, early discharge, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2023.1227217/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/fd747407a391431db5d848301cb198b2

Genome‐wide DNA methylation profiling and identification of potential pan‐cancer and tumor‐specific biomarkers

Authors: Joe Ibrahim, Ken Op de Beeck, Erik Fransen, Marc Peeters, Guy Van Camp

Source: Molecular Oncology, Vol 16, Iss 12, Pp 2432-2447 (2022)

Subject Terms: biomarker, cancer, genome‐wide analysis, methylation, pan‐cancer, tumor‐specific, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/2ca2c857bdde42a083414deb0e1debb3

Performance of non‐invasive myocardial work to predict the first hospitalization for de novo heart failure with preserved ejection fraction

Authors: Pasquale Paolisso, Emanuele Gallinoro, Niya Mileva, Ana Moya, Davide Fabbricatore, Giuseppe Esposito, Cristina De Colle, Monika Beles, Jerrold Spapen, Ward Heggermont, Carlos Collet, Guy Van Camp, Marc Vanderheyden, Emanuele Barbato, Jozef Bartunek, Martin Penicka

Source: ESC Heart Failure, Vol 9, Iss 1, Pp 373-384 (2022)

Subject Terms: HFpEF, Two‐dimensional speckle tracking echocardiography, Non‐invasive myocardial work, Hospitalization, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2055-5822

Access URL: https://doaj.org/article/05498995473748a4872e327f3f1b47b1

Echinacea purpurea (L.) Moench treatment of monocytes promotes tonic interferon signaling, increased innate immunity gene expression and DNA repeat hypermethylated silencing of endogenous retroviral sequences

Authors: Ken Declerck, Claudina Perez Novo, Lisa Grielens, Guy Van Camp, Andreas Suter, Wim Vanden Berghe

Source: BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-20 (2021)

Subject Terms: Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://doaj.org/toc/2662-7671

Access URL: https://doaj.org/article/0b92cd59ae8f48c29ef1fc2f4969c2d0

Antiproliferative, Antiangiogenic, and Antimetastatic Therapy Response by Mangiferin in a Syngeneic Immunocompetent Colorectal Cancer Mouse Model Involves Changes in Mitochondrial Energy Metabolism

Authors: Julio César Rodriguez-Gonzalez, Ivones Hernández-Balmaseda, Ken Declerck, Claudina Pérez-Novo, Emilie Logie, Claudia Theys, Patrycja Jakubek, Olga Luisa Quiñones-Maza, Geovanni Dantas-Cassali, Diego Carlos dos Reis, Guy Van Camp, Miriam Teresa Lopes Paz, Idania Rodeiro-Guerra, René Delgado-Hernández, Wim Vanden Berghe

Source: Frontiers in Pharmacology, Vol 12 (2021)

Subject Terms: Mangiferin (PubChem CID: 5081647), antitumor, antiangiogenesis, antimetastasic, colon carcinoma, mitochondrial metabolism, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2021.670167/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/2c2ad57042394ebf8e1555cab8911302

Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment

Authors: Andries Paul Nagtegaal, Linda Broer, Nuno R. Zilhao, Johanna Jakobsdottir, Charles E. Bishop, Marco Brumat, Mark W. Christiansen, Massimiliano Cocca, Yan Gao, Nancy L. Heard-Costa, Daniel S. Evans, Nathan Pankratz, Sheila R. Pratt, T. Ryan Price, Christopher Spankovich, Mary R. Stimson, Karen Valle, Dragana Vuckovic, Helena Wells, Gudny Eiriksdottir, Erik Fransen, Mohammad Arfan Ikram, Chuang-Ming Li, W. T. Longstreth, Claire Steves, Guy Van Camp, Adolfo Correa, Karen J. Cruickshanks, Paolo Gasparini, Giorgia Girotto, Robert C. Kaplan, Michael Nalls, John M. Schweinfurth, Sudha Seshadri, Nona Sotoodehnia, Gregory J. Tranah, André G. Uitterlinden, James G. Wilson, Vilmundur Gudnason, Howard J. Hoffman, Frances M. K. Williams, André Goedegebure

Source: Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/7621b23b386a4927bee2760a73494186

Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer

Authors: Joe Ibrahim, Ken Op de Beeck, Erik Fransen, Lieselot Croes, Matthias Beyens, Arvid Suls, Wim Vanden Berghe, Marc Peeters, Guy Van Camp

Source: Cancer Medicine, Vol 8, Iss 5, Pp 2133-2145 (2019)

Subject Terms: Biomarker, Colorectal cancer, Diagnosis, DNA methylation, GSDME, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/1cc3393c017c48889df81d998ea79a64

Characteristic ERK1/2 signaling dynamics distinguishes necroptosis from apoptosis

Authors: François Sipieter, Benjamin Cappe, Aymeric Leray, Elke De Schutter, Jolien Bridelance, Paco Hulpiau, Guy Van Camp, Wim Declercq, Laurent Héliot, Pierre Vincent, Peter Vandenabeele, Franck B. Riquet

Source: iScience, Vol 24, Iss 9, Pp 103074- (2021)

Subject Terms: Biological sciences, Biomolecular engineering, Cell biology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004221010427; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/68a7ef265975416abc55a7795e1aa47c

Transduction Efficiency and Immunogenicity of Viral Vectors for Cochlear Gene Therapy: A Systematic Review of Preclinical Animal Studies

Authors: Dorien Verdoodt, Noa Peeleman, Guy Van Camp, Vincent Van Rompaey, Peter Ponsaerts

Source: Frontiers in Cellular Neuroscience, Vol 15 (2021)

Subject Terms: transduction efficiency, inner ear, adeno-associated virus, gene therapy, immunogenicity, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fncel.2021.728610/full; https://doaj.org/toc/1662-5102

Access URL: https://doaj.org/article/908af21b15524884bf9f765dfa0d871b

Cx26 partial loss causes accelerated presbycusis by redox imbalance and dysregulation of Nfr2 pathway

Authors: Anna Rita Fetoni, Veronica Zorzi, Fabiola Paciello, Gaia Ziraldo, Chiara Peres, Marcello Raspa, Ferdinando Scavizzi, Anna Maria Salvatore, Giulia Crispino, Gabriella Tognola, Giulia Gentile, Antonio Gianmaria Spampinato, Denis Cuccaro, Maria Guarnaccia, Giovanna Morello, Guy Van Camp, Erik Fransen, Marco Brumat, Giorgia Girotto, Gaetano Paludetti, Paolo Gasparini, Sebastiano Cavallaro, Fabio Mammano

Source: Redox Biology, Vol 19, Iss , Pp 301-317 (2018)

Subject Terms: Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231718305445; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/4157f176ca6c433d98c82de45af9277e