A nationwide comprehensive genomic profiling and molecular tumor board platform for patients with advanced cancer

Authors: Pieter-Jan Volders, Philippe Aftimos, Franceska Dedeurwaerdere, Geert Martens, Jean-Luc Canon, Gabriela Beniuga, Guy Froyen, Jacques Van Huysse, Rebecca De Pauw, Hans Prenen, Suzan Lambin, Lore Decoster, Freya Vaeyens, Sylvie Rottey, Pieter-Jan Van Dam, Lynn Decoster, Annemie Rutten, Max Schreuer, Siebe Loontiens, Joni Van der Meulen, Jeroen Mebis, Kristof Cuppens, Sabine Tejpar, Isabelle Vanden Bempt, Jacques De Grève, David Schröder, Cédric van Marcke, Marc Van Den Bulcke, Evandro de Azambuja, Kevin Punie, Brigitte Maes

Source: npj Precision Oncology, Vol 9, Iss 1, Pp 1-9 (2025)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2397-768X

Access URL: https://doaj.org/article/e6c17c983f4e45489f70ec83d55744f2

Whole-genome sequencing reveals progressive versus stable myeloma precursor conditions as two distinct entities

Authors: Bénedith Oben, Guy Froyen, Kylee H. Maclachlan, Daniel Leongamornlert, Federico Abascal, Binbin Zheng-Lin, Venkata Yellapantula, Andriy Derkach, Ellen Geerdens, Benjamin T. Diamond, Ingrid Arijs, Brigitte Maes, Kimberly Vanhees, Malin Hultcrantz, Elisabet E. Manasanch, Dickran Kazandjian, Alexander Lesokhin, Ahmet Dogan, Yanming Zhang, Aneta Mikulasova, Brian Walker, Gareth Morgan, Peter J. Campbell, Ola Landgren, Jean-Luc Rummens, Niccolò Bolli, Francesco Maura

Source: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/cf7b932cecac4fc1b4e380aa66de4cb0

Mapping the landscape of tandem repeat variability by targeted long read single molecule sequencing in familial X-linked intellectual disability

Authors: Alena Zablotskaya, Hilde Van Esch, Kevin J. Verstrepen, Guy Froyen, Joris R. Vermeesch

Source: BMC Medical Genomics, Vol 11, Iss 1, Pp 1-17 (2018)

Subject Terms: Tandem repeats, Expansion, Single molecule sequencing, X-linked intellectual disability, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12920-018-0446-7; https://doaj.org/toc/1755-8794

Access URL: https://doaj.org/article/0c42a7bb335c42a3b99df5383aa1527e

A novel fragile X syndrome mutation reveals a conserved role for the carboxy‐terminus in FMRP localization and function

Authors: Zeynep Okray, Celine EF de Esch, Hilde Van Esch, Koen Devriendt, Annelies Claeys, Jiekun Yan, Jelle Verbeeck, Guy Froyen, Rob Willemsen, Femke MS de Vrij, Bassem A Hassan

Source: EMBO Molecular Medicine, Vol 7, Iss 4, Pp 423-437 (2015)

Subject Terms: axon guidance, Drosophila, fragile X syndrome, nuclear export, nucleolus, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/97ced3301746408890cf35b88d3c70ea

Validation and Application of a Custom-Designed Targeted Next-Generation Sequencing Panel for the Diagnostic Mutational Profiling of Solid Tumors.

Authors: Guy Froyen, An Broekmans, Femke Hillen, Karin Pat, Ruth Achten, Jeroen Mebis, Jean-Luc Rummens, Johan Willemse, Brigitte Maes

Source: PLoS ONE, Vol 11, Iss 4, p e0154038 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4839685?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/04e6382cd94b408783919ffa931c36bf

Correction: Ubiquitin Ligase HUWE1 Regulates Axon Branching through the Wnt/β-Catenin Pathway in a Model for Intellectual Disability.

Authors: Joke Vandewalle, Marion Langen, Marlen Zschaetzsch, Bonnie Nijhof, Jamie M. Kramer, Hilde Brems, Marijke Bauters, Elsa Lauwers, Mohammed Srahna, Peter Marynen, Patrik Verstreken, Annette Schenck, Bassem A. Hassan, Guy Froyen

Source: PLoS ONE, Vol 9, Iss 1 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3882180; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/779bbb56762945a9ac29530eafa5a67c

Generation and characterization of an Nxf7 knockout mouse to study NXF5 deficiency in a patient with intellectual disability.

Authors: Lieselot Vanmarsenille, Jelle Verbeeck, Stefanie Belet, Anton J Roebroek, Tom Van de Putte, Joke Nevelsteen, Zsuzsanna Callaerts-Vegh, Rudi D'Hooge, Peter Marynen, Guy Froyen

Source: PLoS ONE, Vol 8, Iss 5, p e64144 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3652825?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/de03510294ce45598248e9eef196dd74

Ubiquitin ligase HUWE1 regulates axon branching through the Wnt/β-catenin pathway in a Drosophila model for intellectual disability.

Authors: Joke Vandewalle, Marion Langen, Marlen Zschätzsch, Bonnie Nijhof, Jamie M Kramer, Hilde Brems, Marijke Bauters, Elsa Lauwers, Mohammed Srahna, Peter Marynen, Patrik Verstreken, Annette Schenck, Bassem A Hassan, Guy Froyen

Source: PLoS ONE, Vol 8, Iss 11, p e81791 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3841167?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/5ed43426dfef4d72af665090c208249c

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Mutations in ionotropic AMPA receptor 3 alter channel properties and are associated with moderate cognitive impairment in humans.

Authors: Ye Wu, Amy C. Arai, Gavin Rumbaugh, Anand K. Srivastava, Gillian Turner, Takashi Hayashid, Erika Suzuki, Yuwu Jiang, Lilei Zhang, Jayson Rodriguez, Jackie Boyle, Patrick Tarpey, F. Lucy Raymond, Joke Nevelsteen, Guy Froyen, Mike Stratton, Andy Futreal, Jozef Gecz, Roger Stevenson, Charles E. Schwartz

Source: Proceedings of the National Academy of Sciences of the United States of America; 11/13/2007, Vol. 104 Issue 45, p18163-18168, 6p

Subject Terms: GENETIC mutation, NEURAL transmission, INTELLECTUAL disabilities, DESENSITIZATION (Psychotherapy), COMPARATIVE genomic hybridization, FOREST spiny pocket mice

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