Clinical and Genomic Characterization of Interval Colorectal Cancer in 3 Prospective Cohorts

Authors: Yang, Keming, Cao, Yin, Gurjao, Carino, Liu, Yang, Guo, Chuan-Guo, Lo, Chun-Han, Zong, Xiaoyu, Drew, David, Geraghty, Connor, Prezioso, Elizabeth, Moore, Matt, Williams, Craig, Riley, Tom, Saul, Melissa, Ogino, Shuji, Giannakis, Marios, Bass, Adam, Schoen, Robert E., Chan, Andrew T.

Source: In Gastroenterology December 2022 163(6):1522-1530

Single-cell and spatial genomic landscape of non-small cell lung cancer brain metastases

Authors: Tagore, Somnath, Caprio, Lindsay, Amin, Amit Dipak, Bestak, Kresimir, Luthria, Karan, D’Souza, Edridge, Barrera, Irving, Melms, Johannes C., Wu, Sharon, Abuzaid, Sinan, Wang, Yiping, Jakubikova, Viktoria, Koch, Peter, Brodtman, D. Zack, Bawa, Banpreet, Deshmukh, Sachin K., Ebel, Leon, Ibarra-Arellano, Miguel A., Jaiswal, Abhinav, Gurjao, Carino, Biermann, Jana, Shaikh, Neha, Ramaradj, Priyanka, Georgis, Yohanna, Lagos, Galina G., Ehrlich, Matthew I., Ho, Patricia, Walsh, Zachary H., Rogava, Meri, Politis, Michelle Garlin, Biswas, Devanik, Cottarelli, Azzurra, Rizvi, Nikhil, Shu, Catherine A., Herzberg, Benjamin, Anandasabapathy, Niroshana, Sledge, George, Zorn, Emmanuel, Canoll, Peter, Bruce, Jeffrey N., Rizvi, Naiyer A., Taylor, Alison M., Saqi, Anjali, Hibshoosh, Hanina, Schwartz, Gary K., Henick, Brian S., Chen, Fei, Schapiro, Denis, Shah, Parin, Izar, Benjamin

Source: Nature Medicine; 20250101, Issue: Preprints p1-13, 13p

Alcohol and colorectal cancer risk, subclassified by mutational signatures of DNA mismatch repair deficiency.

Authors: Fang, Aiping, Ugai, Tomotaka, Gurjao, Carino, Zhong, Rong, Liu, Zhenhua, Zhang, Xinyuan, Wang, Peilu, Nowak, Jonathan, Wang, Molin, Giannakis, Marios, Ogino, Shuji, Zhang, Xuehong, Giovannucci, Edward

Source: JNCI: Journal of the National Cancer Institute; Aug2024, Vol. 116 Issue 8, p1255-1263, 9p

Subject Terms: DNA mismatch repair, PROPORTIONAL hazards models, MEDICAL personnel, ALCOHOL drinking, COLORECTAL cancer

785: CLINICAL AND GENOMIC CHARACTERIZATION OF INTERVAL COLORECTAL CANCER IN THREE PROSPECTIVE COHORTS

Authors: Yang, Keming, Cao, Yin, Liu, Yang, Gurjao, Carino, Guo, Chuan-Guo, Lo, Chun-Han, Zong, Xiaoyu, Drew, David A., Geraghty, Connor M., Prezioso, Elizabeth, Moore, Matthew, Williams, Craig R., Riley, Tom, Saul, Melissa, Diergaarde, Brenda, Ogino, Shuji, Giannakis, Marios, Bass, Adam, Schoen, Robert E., Chan, Andrew

Source: Gastroenterology. 162(7):S-188-S-189

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167624478.0x000001&indx=1&recIds=ETOCvdc_100167624478.0x000001

Metabolomic adaptations and correlates of survival to immune checkpoint blockade

Authors: Li, Haoxin, Bullock, Kevin, Gurjao, Carino, Braun, David, Shukla, Sachet A., Bossé, Dominick, Lalani, Aly-Khan A., Gopal, Shuba, Jin, Chelsea, Horak, Christine, Wind-Rotolo, Megan, Signoretti, Sabina, McDermott, David F., Freeman, Gordon J., Van Allen, Eliezer M., Schreiber, Stuart L., Stephen Hodi, F., Sellers, William R., Garraway, Levi A., Clish, Clary B., Choueiri, Toni K., Giannakis, Marios

Source: Nature communications. 10(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130624610.0x000001&indx=1&recIds=ETOCvdc_100130624610.0x000001

Bayesian risk prediction model for colorectal cancer mortality through integration of clinicopathologic and genomic data.

Authors: Zhao, Melissa, Lau, Mai Chan, Haruki, Koichiro, Väyrynen, Juha P., Gurjao, Carino, Väyrynen, Sara A., Dias Costa, Andressa, Borowsky, Jennifer, Fujiyoshi, Kenji, Arima, Kota, Hamada, Tsuyoshi, Lennerz, Jochen K., Fuchs, Charles S., Nishihara, Reiko, Chan, Andrew T., Ng, Kimmie, Zhang, Xuehong, Meyerhardt, Jeffrey A., Song, Mingyang, Wang, Molin

Source: NPJ Precision Oncology; 6/10/2023, Vol. 7 Issue 1, p1-13, 13p

Subject Terms: COLORECTAL cancer, CANCER-related mortality, PREDICTION models, STATISTICAL learning, CLINICAL pathology

RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.

Authors: Fang, Lishan, Ford-Roshon, Dane, Russo, Max, O'Brien, Casey, Xiong, Xiaozhe, Gurjao, Carino, Grandclaudon, Maximilien, Raghavan, Srivatsan, Corsello, Steven M., Carr, Steven A., Udeshi, Namrata D., Berstler, James, Sicinska, Ewa, Ng, Kimmie, Giannakis, Marios

Source: Nature Communications; 6/8/2022, Vol. 13 Issue 1, p1-12, 12p

Mutational signature in colorectal cancer caused by genotoxic pks+E. coli.

Authors: Pleguezuelos-Manzano, Cayetano, Puschhof, Jens, Rosendahl Huber, Axel, van Hoeck, Arne, Wood, Henry M., Nomburg, Jason, Gurjao, Carino, Manders, Freek, Dalmasso, Guillaume, Stege, Paul B., Paganelli, Fernanda L., Geurts, Maarten H., Beumer, Joep, Mizutani, Tomohiro, Miao, Yi, van der Linden, Reinier, van der Elst, Stefan, Genomics England Research Consortium, Ambrose, J. C., Arumugam, P.

Source: Nature; 4/9/2020, Vol. 580 Issue 7802, p269-273, 5p, 2 Color Photographs, 1 Chart, 7 Graphs

This result is not displayed to guests.
Login for full access.

Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade.

Authors: Sehgal, Kartik, Portell, Andrew, Ivanova, Elena V., Lizotte, Patrick H., Mahadevan, Navin R., Greene, Jonathan R., Vajdi, Amir, Gurjao, Carino, Teceno, Tyler, Taus, Luke J., Thai, Tran C., Shunsuke Kitajima, Liu, Derek, Tetsuo Tani, Noureddine, Moataz, Lau, Christie J., Kirschmeier, Paul T., Liu, David, Giannakis, Marios, Jenkins, Russell W.

Source: Journal of Clinical Investigation. 1/15/2021, Vol. 131 Issue 2, p1-17. 17p. 1 Chart, 6 Graphs.

Subjects: PROGRAMMED cell death 1 receptors, NUCLEOTIDE sequence, RNA sequencing, APOPTOSIS, IMMUNOTHERAPY, TUMOR treatment, PROTEINS, RESEARCH, ANIMAL experimentation, RESEARCH methodology, MEDICAL cooperation, EVALUATION research, COMPARATIVE studies, CELLS, RESEARCH funding, TUMORS, CYTOLOGY, CELL lines, ANTIGENS, MICE