Manganese is a potent inducer of lysosomal activity that inhibits de novo HBV infection

Authors: Lin Yu, Hao Chang, Wentao Xie, Yuan Zheng, Le Yang, Qiong Wu, Fan Bu, Yuanfei Zhu, Youhua Xie, Guoyu Pan, Ke Lan, Qiang Deng

Source: PLoS Pathogens, Vol 21, Iss 1 (2025)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11694974/?tool=EBI; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/3179248283974c89ab377ea37d321029

Applying machine learning for multi-individual Raman spectroscopic data to identify different stages of proliferating human hepatocytes

Authors: Bihan Shen, Chen Ma, Lili Tang, Zhitao Wu, Zhaoliang Peng, Guoyu Pan, Hong Li

Source: iScience, Vol 27, Iss 4, Pp 109500- (2024)

Subject Terms: Physics, Biological sciences, Computer science, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004224007211; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/961045427648436db8b8048f81c644b4

Label‐free Raman spectroscopy for the assessment of liver fibrosis

Authors: Huiying Cao, Chen Ma, Zhitao Wu, Lin Sun, Wenjing Liu, Chenhui Ma, Feihong Chen, Zhaoliang Peng, Lijiang Xuan, Ruimin Huang, Guoyu Pan

Source: MedComm – Future Medicine, Vol 2, Iss 4, Pp n/a-n/a (2023)

Subject Terms: drug response, liver fibrosis, mitochondrial homeostasis, molecular features in situ, Raman spectroscopy and imaging, Medical technology, R855-855.5, Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://doaj.org/toc/2769-6456

Access URL: https://doaj.org/article/d067c899fecf4404b725ee9174f9fa4a

Single cell Raman spectroscopy to identify different stages of proliferating human hepatocytes for cell therapy

Authors: Chen Ma, Ludi Zhang, Ting He, Huiying Cao, Xiongzhao Ren, Chenhui Ma, Jiale Yang, Ruimin Huang, Guoyu Pan

Source: Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2021)

Subject Terms: Raman spectroscopy, Cell therapy, Identification, Proliferating human hepatocytes, Dedifferentiation, Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/da7787a78c2640659bf5c5c3c2acb88c

Gigantol ameliorates CCl4-induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway

Authors: Yaru Xue, Qiangqiang Deng, Qingli Zhang, Zhenghua Ma, Binfan Chen, Xiaolu Yu, Huige Peng, Sheng Yao, Jia Liu, Yang Ye, Guoyu Pan

Source: Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/5422c27e8d144a1294213cea143e9bfe

Survival‐Assured Liver Injury Preconditioning (SALIC) Enables Robust Expansion of Human Hepatocytes in Fah–/–Rag2–/–IL2rg–/– Rats

Authors: Ludi Zhang, Jian‐Yun Ge, Yun‐Wen Zheng, Zhen Sun, Chenhua Wang, Zhaoliang Peng, Baihua Wu, Mei Fang, Kinji Furuya, Xiaolong Ma, Yanjiao Shao, Nobuhiro Ohkohchi, Tatsuya Oda, Jianglin Fan, Guoyu Pan, Dali Li, Lijian Hui

Source: Advanced Science, Vol 8, Iss 19, Pp n/a-n/a (2021)

Subject Terms: bioreactor, humanized liver, liver xeno‐repopulation, pharmacological study, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/4956c6e9b5b94dd8a2f22c16eb0aefd6

Semi‐Flooded Sulfur Cathode with Ultralean Absorbed Electrolyte in Li–S Battery

Authors: Yong Xie, Guoyu Pan, Qiang Jin, Xiaoqun Qi, Tan Wang, Wei Li, Hui Xu, Yuheng Zheng, Sa Li, Long Qie, Yunhui Huang, Ju Li

Source: Advanced Science, Vol 7, Iss 9, Pp n/a-n/a (2020)

Subject Terms: canal–capillary microstructures, fill factor, high‐loading electrodes, lean electrolytes, lithium–sulfur batteries, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/97fc73bd887e48be9842fcb626b66877

Distinct Gene Expression and Epigenetic Signatures in Hepatocyte-like Cells Produced by Different Strategies from the Same Donor

Authors: Yimeng Gao, Xiaoran Zhang, Ludi Zhang, Jin Cen, Xuan Ni, Xiaoying Liao, Chenxi Yang, Ying Li, Xiaotao Chen, Zhao Zhang, Yajing Shu, Xin Cheng, David C. Hay, Dongmei Lai, Guoyu Pan, Gang Wei, Lijian Hui

Source: Stem Cell Reports, Vol 9, Iss 6, Pp 1813-1824 (2017)

Subject Terms: Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671117304745; https://doaj.org/toc/2213-6711

Access URL: https://doaj.org/article/307e7757042448d39eabd5eaba5c3f47

The Protective Effect of Magnesium Lithospermate B on Hepatic Ischemia/Reperfusion via Inhibiting the Jak2/Stat3 Signaling Pathway

Authors: Ning Zhang, Li Han, Yaru Xue, Qiangqiang Deng, Zhitao Wu, Huige Peng, Yiting Zhang, Lijiang Xuan, Guoyu Pan, Qiang Fu

Source: Frontiers in Pharmacology, Vol 10 (2019)

Subject Terms: magnesium lithospermate B, hepatic ischemia/reperfusion, acute injury, anti-inflammation, Jak2/Stat3 signaling pathway, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2019.00620/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/50391370496841c6bae3f666ef32a080

Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-βRI/Smad Signaling

Authors: Xin Luo, Qiangqiang Deng, Yaru Xue, Tianwei Zhang, Zhitao Wu, Huige Peng, Lijiang Xuan, Guoyu Pan

Source: Molecules, Vol 26, Iss 6, p 1715 (2021)

Subject Terms: pulmonary fibrosis, bleomycin, magnesium lithospermate B, transforming growth factor-beta, Smad signaling, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/6/1715; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/90ec9eda642e47188f050a4528d24c2f

Enhanced Anti-diabetic Effect of Berberine Combined With Timosaponin B2 in Goto-Kakizaki Rats, Associated With Increased Variety and Exposure of Effective Substances Through Intestinal Absorption

Authors: Xiaoting Tian, Fang Liu, Zhixiong Li, Yunfei Lin, Huan Liu, Pei Hu, Mingcang Chen, Zhaolin Sun, Zhou Xu, Yiting Zhang, Li Han, Yuanyuan Zhang, Guoyu Pan, Chenggang Huang

Source: Frontiers in Pharmacology, Vol 10 (2019)

Subject Terms: berberine, timosaponin B2, diabetes, combination treatments, drug–drug interaction, metabolites, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2019.00019/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/87f557989a7c4b039ec9c0a8ffeeca16

Effects of chronic intermittent hypoxia on oxidative stress and inflammatory response and the interventional roles of adiponectin

Authors: Guoyu, Pan, Mei, Su, Wenxiao, Ding

Source: Zhonghua yi xue za zhi. 95(16):1218-1221

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN601674620&indx=1&recIds=ETOCRN601674620

HDAC inhibitor-induced drug resistance involving ATP-binding cassette transporters (Review).

Authors: XUAN NI, LI LI, GUOYU PAN

Source: Oncology Letters; 2015, Vol. 9 Issue 2, p515-521, 7p

Subject Terms: HISTONE deacetylase, ANTINEOPLASTIC agents, CANCER treatment, T-cell lymphoma, ADENOSINE triphosphate, ATP-binding cassette transporters, NUCLEAR receptors (Biochemistry)

Assessment of Biliary Clearance in Early Drug Discovery Using Sandwich-Cultured Hepatocyte Model.

Authors: GUOYU PAN¹, BOISELLE, CARRI², JIANLING WANG² jianling.wang@novartis.com

Source: Journal of Pharmaceutical Sciences. May2012, Vol. 101 Issue 5, p1898-1908. 11p.

Subject Terms: *LIVER cells, *CELL culture, *DRUG interactions, *DRUG metabolism, *IN vitro studies

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