Immune Cell Dynamics in EGFR-Mutated NSCLC Treated With Afatinib and Pembrolizumab: Results From a Phase IB Study

Authors: Jonathan W. Riess, MD, Matthew S. Lara, BS, Miguel Lopez de Rodas, MD, Guillaume Luxardi, PhD, Samantha Herbert, MSPH, Michiko Shimoda, PhD, Karen Kelly, MD, Alexander Meerlev, PhD, Elizabeth Moore, MD, Laurel Beckett, PhD, Arta Monjazeb, MD, PhD, Kurt Schalper, MD, PhD, Emanual Maverakis, MD, David R. Gandara, MD

Source: JTO Clinical and Research Reports, Vol 5, Iss 10, Pp 100706- (2024)

Subject Terms: Lung cancer, Epidermal growth factor, Immunotherapy, Targeted therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666364324000766; https://doaj.org/toc/2666-3643

Access URL: https://doaj.org/article/863cfd19d5dc48c7a90762bd86354f28

Atezolizumab plus stereotactic ablative radiotherapy for medically inoperable patients with early-stage non-small cell lung cancer: a multi-institutional phase I trial

Authors: Arta M. Monjazeb, Megan E. Daly, Guillaume Luxardi, Emanual Maverakis, Alexander A. Merleev, Alina I. Marusina, Alexander Borowsky, Amin Mirhadi, Stephen L. Shiao, Laurel Beckett, Shuai Chen, David Eastham, Tianhong Li, Logan V. Vick, Heather M. McGee, Frances Lara, Leslie Garcia, Leigh Anne Morris, Robert J. Canter, Jonathan W. Riess, Kurt A. Schalper, William J. Murphy, Karen Kelly

Source: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/28952647439e48d680160b1ba89a37c4

Transcriptome analysis of human dermal fibroblasts following red light phototherapy

Authors: Evan Austin, Eugene Koo, Alexander Merleev, Denis Torre, Alina Marusina, Guillaume Luxardi, Andrew Mamalis, Roslyn Rivkah Isseroff, Avi Ma’ayan, Emanual Maverakis, Jared Jagdeo

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/1a227c143dba4b9495dc0bf4c116257c

Proprotein convertase subtilisin/kexin type 9 is a psoriasis-susceptibility locus that is negatively related to IL36G

Authors: Alexander Merleev, Antonio Ji-Xu, Atrin Toussi, Lam C. Tsoi, Stephanie T. Le, Guillaume Luxardi, Xianying Xing, Rachael Wasikowski, William Liakos, Marie-Charlotte Brüggen, James T. Elder, Iannis E. Adamopoulos, Yoshihiro Izumiya, Annie R. Leal, Qinyuan Li, Nikolay Y. Kuzminykh, Amanda Kirane, Alina I. Marusina, Johann E. Gudjonsson, Emanual Maverakis

Source: JCI Insight, Vol 7, Iss 16 (2022)

Subject Terms: Autoimmunity, Dermatology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/0af5f0392e5144bb91cb11d1e06f87ed

Biogeographic and disease-specific alterations in epidermal lipid composition and single-cell analysis of acral keratinocytes

Authors: Alexander A. Merleev, Stephanie T. Le, Claire Alexanian, Atrin Toussi, Yixuan Xie, Alina I. Marusina, Steven M. Watkins, Forum Patel, Allison C. Billi, Julie Wiedemann, Yoshihiro Izumiya, Ashish Kumar, Ranjitha Uppala, J. Michelle Kahlenberg, Fu-Tong Liu, Iannis E. Adamopoulos, Elizabeth A. Wang, Chelsea Ma, Michelle Y. Cheng, Halani Xiong, Amanda Kirane, Guillaume Luxardi, Bogi Andersen, Lam C. Tsoi, Carlito B. Lebrilla, Johann E. Gudjonsson, Emanual Maverakis

Source: JCI Insight, Vol 7, Iss 16 (2022)

Subject Terms: Dermatology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/29f7b5c3c7314462ae63385c896e06c5

Early redox activities modulate Xenopus tail regeneration

Authors: Fernando Ferreira, VijayKrishna Raghunathan, Guillaume Luxardi, Kan Zhu, Min Zhao

Source: Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f3ab9ec838cc49768feff3e1cc2f2ef9

2D Visualization of the Psoriasis Transcriptome Fails to Support the Existence of Dual-Secreting IL-17A/IL-22 Th17 T Cells

Authors: Stephanie T. Le, Alexander A. Merleev, Guillaume Luxardi, Michiko Shimoda, Iannis E. Adamopoulos, Lam C. Tsoi, Jenny Z. Wang, Claire Alexanian, Siba P. Raychaudhuri, Samuel T. Hwang, Johann Gudjonsson, Alina I. Marusina, Emanual Maverakis

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: IL17, IL22, machine learning, neutrophil, psoriasis, RNA-seq, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.00589/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/ee793b68b8a74bf49f481c9601c520be

Infection-generated electric field in gut epithelium drives bidirectional migration of macrophages.

Authors: Yaohui Sun, Brian Reid, Fernando Ferreira, Guillaume Luxardi, Li Ma, Kristen L Lokken, Kan Zhu, Gege Xu, Yuxin Sun, Volodymyr Ryzhuk, Betty P Guo, Carlito B Lebrilla, Emanual Maverakis, Alex Mogilner, Min Zhao

Source: PLoS Biology, Vol 17, Iss 4, p e3000044 (2019)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/88c7cf53dc304ac887f6d9ef388fdeaf

Classic Ulcerative Pyoderma Gangrenosum Is a T Cell-Mediated Disease Targeting Follicular Adnexal Structures: A Hypothesis Based on Molecular and Clinicopathologic Studies

Authors: Elizabeth A. Wang, Andrea Steel, Guillaume Luxardi, Anupam Mitra, Forum Patel, Michelle Y. Cheng, Reason Wilken, Jason Kao, Kristopher de Ga, Hawa Sultani, Alexander A. Merleev, Alina I. Marusina, Alain Brassard, Maxwell A. Fung, Thomas Konia, Michiko Shimoda, Emanual Maverakis

Source: Frontiers in Immunology, Vol 8 (2018)

Subject Terms: pyoderma gangrenosum, CD4, T cell, autoimmune, cytokine, pilosebaceous unit, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fimmu.2017.01980/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/fe3ea2b9197646ba9e0c3fd94e1b89c6

Ventx factors function as Nanog-like guardians of developmental potential in Xenopus.

Authors: Pierluigi Scerbo, Fabrice Girardot, Céline Vivien, Gabriel V Markov, Guillaume Luxardi, Barbara Demeneix, Laurent Kodjabachian, Laurent Coen

Source: PLoS ONE, Vol 7, Iss 5, p e36855 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3351468?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/9b009d475c41471ebfce853cd84048f7

Measurement of Extracellular Ion Fluxes Using the Ion-selective Self-referencing Microelectrode Technique

Authors: Guillaume Luxardi, author¹, Brian Reid, author¹, Fernando Ferreira, author^{1, 2}, Pauline Maillard, author³, Min Zhao, author^{1, 4}

Source: Journal of Visualized Experiments. (99)

Availability: http://www.jove.com/video/52782

Metastasis of cholangiocarcinoma is promoted byextended high-mannose glycans.

Authors: Park a, Diane Dayoung, b, Chatchai Phoomak, a, Gege Xu, Olney c, Laura P., Tran c, Khiem A., Park d, Simon S., Haigh c, Nathan E., c, Guillaume Luxardi, b, Worachart Lert-itthiporn, c, Michiko Shimoda, a, Qiongyu Li, e, Nobuyuki Matoba, f, Fernando Fierro, b, Sopit Wongkham, c, Emanual Maverakis, Lebrilla a, Carlito B.

Source: Proceedings of the National Academy of Sciences of the United States of America; 4/7/2020, Vol. 117 Issue 14, p7633-7644, 12p

Subject Terms: MEMBRANE proteins, BILIARY tract cancer, GLYCANS, MEMBRANE glycoproteins, TRANSFERRIN receptors