YHSeqY3000 panel captures all founding lineages in the Chinese paternal genomic diversity database

Authors: Mengge Wang, Shuhan Duan, Qiuxia Sun, Kaijun Liu, Yan Liu, Zhiyong Wang, Xiangping Li, Lanhai Wei, Yunhui Liu, Shengjie Nie, Kun Zhou, K_CPGDP consortium, Yongxin Ma, Huijun Yuan, Bing Liu, Lan Hu, Chao Liu, Guanglin He

Source: BMC Biology, Vol 23, Iss 1, Pp 1-20 (2025)

Subject Terms: YanHuang cohort, Genomic diversity database, YHSeqY3000 panel, Forensic genomics, Human evolution, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7007

Access URL: https://doaj.org/article/e9ce2e4ac20346019040cc7699f78d1c

Dissecting the genetic admixture and forensic signatures of ethnolinguistically diverse Chinese populations via a 114-plex NGS InDel panel

Authors: Chengliang Yang, Changhui Liu, Miaoqiang Lun, Xiaohui Chen, Quyi Xu, Xueyuan Liu, Meiyun He, Linying Ye, Guanglin He, Mengge Wang, Chao Liu

Source: BMC Genomics, Vol 25, Iss 1, Pp 1-12 (2024)

Subject Terms: InDel, Next-generation sequencing, Genetic diversity, Population structure, Forensic characterization, Biotechnology, TP248.13-248.65, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/4702b258c09f40c4bc1aa1b5100997d4

Population genomics of Central Asian peoples unveil ancient Trans-Eurasian genetic admixture and cultural exchanges

Authors: Guanglin He, Mengge Wang, Lintao Luo, Qiuxia Sun, Haibing Yuan, Hongliang Lv, Yuhang Feng, Xiaojun Liu, Jing Cheng, Fengxiao Bu, Maxat Zhabagin, Huijun Yuan, Chao Liu, Shuhua Xu

Source: hLife, Vol 2, Iss 11, Pp 554-562 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2949928324000555; https://doaj.org/toc/2949-9283

Access URL: https://doaj.org/article/8d284ff884ee4d7cb62bdb6bc84c1ea6

The large-scale whole-genome sequencing era expedited medical discovery and clinical translation

Authors: Qingxin Yang, Shuhan Duan, Yuguo Huang, Chao Liu, Mengge Wang, Guanglin He

Source: EngMedicine, Vol 2, Iss 1, Pp 100055- (2025)

Subject Terms: Genomic projects, Multi-omics, Fundamental genomic research, Clinical translation, Medical technology, R855-855.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2950489925000016; https://doaj.org/toc/2950-4899

Access URL: https://doaj.org/article/e3db1aeae7ae42a39439439d52638d52

Genetic history and biological adaptive landscape of the Tujia people inferred from shared haplotypes and alleles

Authors: Jing Chen, Mengge Wang, Shuhan Duan, Qingxin Yang, Yan Liu, Mengyang Zhao, Qiuxia Sun, Xiangping Li, Yuntao Sun, Haoran Su, Zhiyong Wang, Yuguo Huang, Jie Zhong, Yuhang Feng, Xiaomeng Zhang, Guanglin He, Jiangwei Yan

Source: Human Genomics, Vol 18, Iss 1, Pp 1-17 (2024)

Subject Terms: Demographic history, Genetic structure, Genetic admixture, Biological adaptation, Tujia, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1479-7364

Access URL: https://doaj.org/article/75fc5b3d622344499a62f4a36446d664

Genomic insights into Neolithic founding paternal lineages around the Qinghai-Xizang Plateau using integrated YanHuang resource

Authors: Mengge Wang, Yunhui Liu, Lintao Luo, Yuhang Feng, Zhiyong Wang, Ting Yang, Huijun Yuan, Chao Liu, Guanglin He

Source: iScience, Vol 27, Iss 12, Pp 111456- (2024)

Subject Terms: Evolutionary biology, Paleobiology, Anthropology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S258900422402683X; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/81399b5fc71b45d1832ef03093c7349c

Population genetic admixture and evolutionary history in the Shandong Peninsula inferred from integrative modern and ancient genomic resources

Authors: Haoran Su, Mengge Wang, Xiangping Li, Shuhan Duan, Qiuxia Sun, Yuntao Sun, Zhiyong Wang, Qingxin Yang, Yuguo Huang, Jie Zhong, Jing Chen, Xiucheng Jiang, Jinyue Ma, Ting Yang, Yunhui Liu, Lintao Luo, Yan Liu, Junbao Yang, Gang Chen, Chao Liu, Yan Cai, Guanglin He

Source: BMC Genomics, Vol 25, Iss 1, Pp 1-20 (2024)

Subject Terms: Population genetics, Northern Han, Evolution, Genomics, Adaptation, Biotechnology, TP248.13-248.65, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/4ae7d25ac3dd4074acd2aef17b5ceef5

Differentiated adaptative genetic architecture and language-related demographical history in South China inferred from 619 genomes from 56 populations

Authors: Qiuxia Sun, Mengge Wang, Tao Lu, Shuhan Duan, Yan Liu, Jing Chen, Zhiyong Wang, Yuntao Sun, Xiangping Li, Shaomei Wang, Liuyi Lu, Liping Hu, Libing Yun, Junbao Yang, Jiangwei Yan, Shengjie Nie, Yanfeng Zhu, Gang Chen, Chuan-Chao Wang, Chao Liu, Guanglin He, Renkuan Tang

Source: BMC Biology, Vol 22, Iss 1, Pp 1-24 (2024)

Subject Terms: Demographical history, Biological adaptation, Genetic structure, Genomic diversity, Han Chinese, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7007

Access URL: https://doaj.org/article/9d41cacf018c4cedbba36991b232f23c

Differentiated genomic footprints suggest isolation and long-distance migration of Hmong-Mien populations

Authors: Guanglin He, Peixin Wang, Jing Chen, Yan Liu, Yuntao Sun, Rong Hu, Shuhan Duan, Qiuxia Sun, Renkuan Tang, Junbao Yang, Zhiyong Wang, Libing Yun, Liping Hu, Jiangwei Yan, Shengjie Nie, Lanhai Wei, Chao Liu, Mengge Wang

Source: BMC Biology, Vol 22, Iss 1, Pp 1-26 (2024)

Subject Terms: Genetic diversity, Demographic history, Admixture events, Hmong-Mien speaker, Differentiated genetic structure, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7007

Access URL: https://doaj.org/article/f6cb463c3b6b4e259e5e68103046e514

Genomic formation of Tibeto-Burman speaking populations in Guizhou, Southwest China

Authors: Jinwen Chen, Han Zhang, Meiqing Yang, Rui Wang, Hongling Zhang, Zheng Ren, Qiyan Wang, Yubo Liu, Jing Chen, Jingyan Ji, Jing Zhao, Guanglin He, Jianxin Guo, Kongyang Zhu, Xiaomin Yang, Hao Ma, Chuan-Chao Wang, Jiang Huang

Source: BMC Genomics, Vol 24, Iss 1, Pp 1-17 (2023)

Subject Terms: Genetic structure, Admixture history, Gene flow, Tibeto-Burman, Guizhou, Southwest China, Biotechnology, TP248.13-248.65, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/0155b042dd7942e48281363b12fb1246

Developmental validation of a high-resolution panel genotyping 639 Y-chromosome SNP and InDel markers and its evolutionary features in Chinese populations

Authors: Guang-Bin Zhao, Lei Miao, Mengge Wang, Jia-Hui Yuan, Lan-Hai Wei, Yao-Sen Feng, Jie Zhao, Ke-Lai Kang, Chi Zhang, An-Quan Ji, Guanglin He, Le Wang

Source: BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)

Subject Terms: Forensic genetics, Y-chromosome, Single nucleotide polymorphism, Next-generation sequencing, Haplogroup inference, Biotechnology, TP248.13-248.65, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/9530fb47c00b4417aad8b414dfa13973

Editorial: Full landscape of human genomic diversity and its impact on precision medicine

Authors: Guanglin He, Hui-Yuan Yeh, Mengge Wang

Source: Frontiers in Genetics, Vol 15 (2024)

Subject Terms: genomic diversity, fine-scale population substructure, genome-wide SNP, paternal structure, maternal lineages, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2024.1432509/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/98574bc1e38544e083df8b671ba9ed70

Genetic history of esophageal cancer group in southwestern China revealed by Y‐chromosome STRs and genomic evolutionary connection analysis

Authors: Lihua Jia, Mengge Wang, Shuhan Duan, Jianghua Chen, Mei Zhao, Simeng Ji, Bingbing Lv, Xiucheng Jiang, Guanglin He, Junbao Yang

Source: Heliyon, Vol 10, Iss 9, Pp e29867- (2024)

Subject Terms: Genetic diversity, Population origin, Disease susceptibility, Han Chinese, Esophageal cancer, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024058985; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/3572717353d44e67a4814fa7739633b3

Evolutionary profiles and complex admixture landscape in East Asia: New insights from modern and ancient Y chromosome variation perspectives

Authors: Zhiyong Wang, Mengge Wang, Liping Hu, Guanglin He, Shengjie Nie

Source: Heliyon, Vol 10, Iss 9, Pp e30067- (2024)

Subject Terms: Founding lineage, Y-chromosome genetic diversity, Genomic resources, East Asian, Evolutionary history, Ancient DNA, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024060985; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/813a0e2204d048ceb58b748c789083d5

Malaria resistance-related biological adaptation and complex evolutionary footprints inferred from one integrative Tai-Kadai-related genomic resource

Authors: Shuhan Duan, Mengge Wang, Zhiyong Wang, Yan Liu, Xiucheng Jiang, Haoran Su, Yan Cai, Qiuxia Sun, Yuntao Sun, Xiangping Li, Jing Chen, Yijiu Zhang, Jiangwei Yan, Shengjie Nie, Liping Hu, Renkuan Tang, Libing Yun, Chuan-Chao Wang, Chao Liu, Junbao Yang, Guanglin He

Source: Heliyon, Vol 10, Iss 8, Pp e29235- (2024)

Subject Terms: Biological adaptation, Genetic admixture, Population history, Tai-Kadai people, Malaria resistance, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024052666; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/0615f8e1c0c14499b3802d2431643569

Extensive genetic admixture between Tai-Kadai-speaking people and their neighbours in the northeastern region of the Yungui Plateau inferred from genome-wide variations

Authors: Jiawen Wang, Jun Wu, Qiuxia Sun, Qian Wu, Youjing Li, Shuhan Duan, Lin Yang, Wenxin Wu, Zheng Wang, Yan Liu, Renkuan Tang, Junbao Yang, Chuanchao Wang, Chao Liu, Jianwei Xu, Mengge Wang, Guanglin He

Source: BMC Genomics, Vol 24, Iss 1, Pp 1-17 (2023)

Subject Terms: Biological adaptation, Genome-wide SNPs, Genetic admixture model, TK people, Biotechnology, TP248.13-248.65, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/39971599a07f462b911872b642932f4f

Multiple founding paternal lineages inferred from the newly-developed 639-plex Y-SNP panel suggested the complex admixture and migration history of Chinese people

Authors: Guanglin He, Mengge Wang, Lei Miao, Jing Chen, Jie Zhao, Qiuxia Sun, Shuhan Duan, Zhiyong Wang, Xiaofei Xu, Yuntao Sun, Yan Liu, Jing Liu, Zheng Wang, Lanhai Wei, Chao Liu, Jian Ye, Le Wang

Source: Human Genomics, Vol 17, Iss 1, Pp 1-17 (2023)

Subject Terms: Phylogenetic tree, Y-SNPs, Population structure, Founding lineage, Network relationship, Biogeographical ancestry inference, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1479-7364

Access URL: https://doaj.org/article/9846d74174c84e1ebda4d13fde127a72

Genome-wide allele and haplotype-sharing patterns suggested one unique Hmong–Mein-related lineage and biological adaptation history in Southwest China

Authors: Guanglin He, Jiawen Wang, Lin Yang, Shuhan Duan, Qiuxia Sun, Youjing Li, Jun Wu, Wenxin Wu, Zheng Wang, Yan Liu, Renkuan Tang, Junbao Yang, Chao Liu, Buhong Yuan, Daoyong Wang, Jianwei Xu, Mengge Wang

Source: Human Genomics, Vol 17, Iss 1, Pp 1-17 (2023)

Subject Terms: Genetic structure, Evolutionary history, Miao, Admixture model, Biological adaptation, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1479-7364

Access URL: https://doaj.org/article/0f335c1d552746518389a31c2c17dcd8

The complex genetic landscape of southwestern Chinese populations contributed to their extensive ethnolinguistic diversity

Authors: Mengge Wang, Shuhan Duan, Qiuxia Sun, Yan Liu, Renkuan Tang, Junbao Yang, Pengyu Chen, Chao Liu, Hongyu Sun, Guanglin He

Source: Frontiers in Ecology and Evolution, Vol 11 (2023)

Subject Terms: ethnolinguistic diversity, genome-wide SNP, genetic diversity, admixture events, evolutionary history, Evolution, QH359-425, Ecology, QH540-549.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fevo.2023.1235655/full; https://doaj.org/toc/2296-701X

Access URL: https://doaj.org/article/177ca9f7847a4149bc1a85b2dd37355d

Genetic admixture history and forensic characteristics of Tibeto-Burman-speaking Qiang people explored via the newly developed Y-STR panel and genome-wide SNP data

Authors: Guanglin He, Atif Adnan, Wedad Saeed Al-Qahtani, Fatmah Ahmed Safhi, Hui-Yuan Yeh, Sibte Hadi, Chuan-Chao Wang, Mengge Wang, Chao Liu, Jun Yao

Source: Frontiers in Ecology and Evolution, Vol 10 (2022)

Subject Terms: validation, Y-STRs, forensic genetics, Qiang, genome-wide SNP, admixture history, Evolution, QH359-425, Ecology, QH540-549.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fevo.2022.939659/full; https://doaj.org/toc/2296-701X

Access URL: https://doaj.org/article/3ccfcd6462534f9cb696d3a49f3792b2