Structural basis of promiscuous inhibition of Listeria virulence activator PrfA by oligopeptides

Authors: Hainzl, Tobias ¹, Scortti, Mariela ², Lindgren, Cecilia ¹, Grundström, Christin ¹, Krypotou, Emilia ², Vázquez-Boland, José A. ^{2, ∗}, Sauer-Eriksson, A. Elisabeth ^{1, 3, ∗∗}

Source: In Cell Reports 25 February 2025 44(2)

Dynamic Connection between Enzymatic Catalysis and Collective Protein Motions

Authors: Ojeda-May, Pedro, Mushtaq, Ameeq Ul, Rogne, Per, Verma, Apoorv, Ovchinnikov, Victor, Grundström, Christin, Dulko-Smith, Beata, Sauer, Uwe H., Wolf-Watz, Magnus, Nam, Kwangho

Source: Biochemistry. 60(28):2246-2258

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN627258699&indx=1&recIds=ETOCRN627258699

Structural Basis for GTP versus ATP Selectivity in the NMP Kinase AK3

Authors: Rogne, Per, Dulko-Smith, Beata, Goodman, Jack, Rosselin, Marie, Grundström, Christin, Hedberg, Christian, Nam, Kwangho, Sauer-Eriksson, A. Elisabeth, Wolf-Watz, Magnus

Source: Biochemistry. 59(38):3570-3581

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625038207&indx=1&recIds=ETOCRN625038207

Control of Bacterial Virulence through the Peptide Signature of the Habitat

Authors: Krypotou, Emilia, Scortti, Mariela, Grundström, Christin, Oelker, Melanie, Luisi, Ben F., Sauer-Eriksson, A. Elisabeth, Vázquez-Boland, José

Source: In Cell Reports 12 February 2019 26(7):1815-1827

Screening for Inhibitors of Acetaldehyde Dehydrogenase (AdhE) from Enterohemorrhagic Escherichia coli (EHEC)

Authors: Zetterström, Caroline E., Uusitalo, Pia, Qian, Weixing, Hinch, Shannon, Caraballo, Rémi, Grundström, Christin, Elofsson, Mikael ^*

Source: In SLAS Discovery September 2018 23(8):815-822

Nucleation of an Activating Conformational Change by a Cation-π Interaction

Authors: Rogne, Per, Andersson, David, Grundström, Christin, Sauer-Eriksson, Elisabeth, Linusson, Anna, Wolf-Watz, Magnus

Source: Biochemistry. 58(32):3408-3412

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN621313793&indx=1&recIds=ETOCRN621313793

Molecular mechanism of ATP versus GTP selectivity of adenylate kinase

Authors: Rogne, Per, Rosselin, Marie, Grundström, Christin, Hedberg, Christian, Sauer, Uwe H., Wolf-Watz, Magnus

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Mar . 115(12), 3012-3017.

Access URL: https://www.jstor.org/stable/26509004

Structural basis for ligand binding to an enzyme by a conformational selection pathway

Authors: Kovermann, Michael, Grundström, Christin, Sauer-Eriksson, A. Elisabeth, Sauer, Uwe H., Wolf-Watz, Magnus

Source: Proceedings of the National Academy of Sciences of the United States of America, 2017 Jun . 114(24), 6298-6303.

Access URL: https://www.jstor.org/stable/26484208

Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals

Authors: Zhang, Jin, Grundström, Christin, Brännström, Kristoffer, Iakovleva, Irina, Lindberg, Mikael, Olofsson, Anders, Andersson, Patrik L., Sauer-Eriksson, A. Elisabeth

Source: Environmental science & technology. 52(20):11865-11874

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Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria

Authors: Hall, Michael, Grundström, Christin, Begum, Afshan, Lindberg, Mikael J., Sauer, Uwe H., Almqvist, Fredrik, Johansson, Jörgen, Sauer-Eriksson, A. Elisabeth

Source: Proceedings of the National Academy of Sciences of the United States of America, 2016 Dec . 113(51), 14733-14738.

Access URL: https://www.jstor.org/stable/26472949

Crystal Structure and Functional Characterization of Photosystem II-Associated Carbonic Anhydrase CAH3 in Chlamydomonas reinhardtii

Authors: Benlloch, Reyes, Shevela, Dmitriy, Hainzl, Tobias, Grundström, Christin, Shutova, Tatyana, Messinger, Johannes, Samuelsson, Göran, Sauer-Eriksson, A. Elisabeth

Source: Plant Physiology, 2015 Mar 01. 167(3), 950-962.

Access URL: https://www.jstor.org/stable/24801801

Domain isolation, expression, purification and proteolytic activity of the metalloprotease PrtV from Vibrio cholerae

Authors: Edwin, Aaron, Grundström, Christin, Wai, Sun N., Öhman, Anders, Stier, Gunter, Sauer-Eriksson, A. Elisabeth

Source: In Protein Expression and Purification April 2014 96:39-47

Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA

Authors: Good, James A.D., Andersson, Christopher, Hansen, Sabine, Wall, Jessica, Krishnan, K. Syam, Begum, Afshan, Grundström, Christin, Niemiec, Moritz S., Vaitkevicius, Karolis, Chorell, Erik, Wittung-Stafshede, Pernilla, Sauer, Uwe H., Sauer-Eriksson, A. Elisabeth, Almqvist, Fredrik, Johansson, Jörgen

Source: Cell chemical biology. 23(3):404-414

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100042754401.0x000001&indx=1&recIds=ETOCvdc_100042754401.0x000001

Structure-Based Virtual Screening Protocol for in Silico Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin

Authors: Zhang, Jin, Begum, Afshan, Brännström, Kristoffer, Grundström, Christin, Iakovleva, Irina, Olofsson, Anders, Sauer-Eriksson, A. Elisabeth, Andersson, Patrik L.

Source: Environmental science & technology. 50(21):11984-11993

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN608784663&indx=1&recIds=ETOCRN608784663

Elucidating Dynamics of Adenylate Kinase from Enzyme Opening to Ligand Release.

Authors: Nam, Kwangho, Arattu Thodika, Abdul Raafik, Grundström, Christin, Sauer, Uwe H., Wolf-Watz, Magnus

Source: Journal of Chemical Information & Modeling; 1/8/2024, Vol. 64 Issue 1, p150-163, 14p

Structural basis of promiscuous inhibition of Listeriavirulence activator PrfA by oligopeptides

Authors: Hainzl, Tobias, Scortti, Mariela, Lindgren, Cecilia, Grundström, Christin, Krypotou, Emilia, Vázquez-Boland, José A., Sauer-Eriksson, A. Elisabeth

Source: Cell Reports; February 2025, Vol. 44 Issue: 2

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Inactivating the main Listeria monocytogenes virulence regulator PrfA with ring-fused 2-pyridones
Meeting on Microbial Pathogenesis & Host Response

Authors: Hansen, Sabine, Good, James A., Andersson, Christopher, Wall, Jessica, Krishnan, Syam, Grundström, Christin, Niemiec, Moritz S., Vaitkevicius, Karolis, Chorell, Erik, Sauer, Uwe H.

Source: Abstracts of papers presented at the ... meeting on microbial pathogenesis & host response. 1000004:60-60

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCCN603300279&indx=1&recIds=ETOCCN603300279

Nucleation of an Activating Conformational Change by a Cation−π Interaction.

Authors: Rogne, Per, Andersson, David, Grundström, Christin, Sauer-Eriksson, Elisabeth, Linusson, Anna, Wolf-Watz, Magnus

Source: Biochemistry; 8/13/2019, Vol. 58 Issue 32, p3408-3412, 5p

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