Irinotecan and temozolomide in combination with dasatinib and rapamycin versus irinotecan and temozolomide for patients with relapsed or refractory neuroblastoma (RIST-rNB-2011): a multicentre, open-label, randomised, controlled, phase 2 trial

Authors: Corbacioglu, Selim ^*, Lode, Holger, Ellinger, Susanne, Zeman, Florian, Suttorp, Meinolf, Escherich, Gabriele, Bochennek, Konrad, Gruhn, Bernd, Lang, Peter, Rohde, Marius, Debatin, Klaus Michael, Steinbach, Daniel, Beilken, Andreas, Ladenstein, Ruth, Spachtholz, Rainer, Heiss, Peter, Hellwig, Dirk, Tröger, Anja, Koller, Michael, Menhart, Karin, Riemenschneider, Markus J, Zoubaa, Saida, Kietz, Silke, Jakob, Marcus, Sommer, Gunhild, Heise, Tilman, Hundsdörfer, Patrick, Kühnle, Ingrid, Dilloo, Dagmar, Schönberger, Stefan, Schwabe, Georg, von Luettichau, Irene, Graf, Norbert, Schlegel, Paul-Gerhardt, Frühwald, Michael, Jorch, Norbert, Paulussen, Michael, Schneider, Dominik T, Metzler, Markus, Leipold, Alfred, Nathrath, Michaela, Imschweiler, Thomas, Christiansen, Holger, Schmid, Irene, Crazzolara, Roman, Niktoreh, Naghmeh, Cario, Gunnar, Faber, Joerg, Demmert, Martin, Babor, Florian, Fröhlich, Birgit, Bielack, Stefan, Bernig, Toralf, Greil, Johann, Eggert, Angelika, Simon, Thorsten, Foell, Juergen

Source: In The Lancet Oncology July 2024 25(7):922-932

Influence of ATLG serum levels on CD3/CD19-depleted hematopoietic grafts and on immune recovery in pediatric haplo-HSCT

Authors: Maier, Claus-Philipp, Klose, Chihab, Seitz, Christian Martin, Heubach, Florian, Döring, Michaela, Meisel, Roland, Schuster, Friedhelm, Gruhn, Bernd, Keller, Frieder, Rabsteyn, Armin, Arendt, Anne-Marie, Amorelli, Germano, Eichholz, Thomas, Feuchtinger, Tobias, Martinius, Holger, Nierkens, Stefan, Teltschik, Rouwen, Schulte, Johannes Hubertus, Lengerke, Claudia, Handgretinger, Rupert, Lang, Peter

Source: In Blood Advances 14 May 2024 8(9):2160-2171

Diagnostic evaluation of paediatric autoimmune lymphoproliferative immunodeficiencies (ALPID): a prospective cohort study

Authors: Abinun, Mario, Abrahamsen, Tore G., Albert, Michael H., Almalky, Mohamed, Altaf, Sadaf, Babayeva, Royala, Bakhtiar, Shahrzad, Baris, Safa, Baumann, Ulrich, Becker, Martina, Beier, Rita, Berger, Thomas, Biebl, Ariane, Bielack, Stefan S., Biskup, Saskia, Bode, Sebastian FN, Borchers, Regine, Boztug, Kaan, Brockmann, Knut, Bruwier, Annelyse, Buchholz, Bernd, Caballero-Oteyza, Andres, Cant, Andrew J., Castro, Carla N., Classen, Carl F., Claviez, Alexander, Crazzolara, Roman, Cuntz, Franziska, Dąbrowska-Leonik, Nel, Derichs, Ute, Dückers, Gregor, Eberl, Wolfgang, Ebetsberger-Dachs, Georg, Erlacher, Miriam, Fabre, Alexandre, Faletti, Laura, Farmand, Susan, Figueiredo, Antonio E., Fischer, Marco, Flaadt, Tim, Full, Hermann, Gambineri, Eleonora, Girschick, Hermann, Goldacker, Sigune, Grimbacher, Bodo, Groß, Miriam, Gruhn, Bernd, Haberfellner, Florian, Hague, Rosie, Hauch, Holger, Hauck, Fabian, Heine, Sabine, Huisman, Elise J., Jakovljevic, Gordana, James, Beki, Janda, Ales, Jones, Neil, Kaiser-Labusch, Petra, Kentouche, Karim, Knight, Julian C., Knirsch, Stephanie, Kontny, Udo, Körholz, Julia, Krenn, Thomas, Kuehnle, Ingrid, Kühne, Thomas, Lee-Dimroth, Jae-Yun, Lehmann, Hartwig, Leipold, Alfred, Meinhardt, Andrea, Minkov, Milen, Mönkemöller, Kirsten, Morbach, Henner, Mücke, Urs, Nathrath, Michaela, Naumann-Bartsch, Nora, Neth, Olaf, Niemeyer, Charlotte M., Olbrich, Peter, Ostró, Róbert, Owens, Stephen, Pac, Malgorzata, Pachlopnik Schmid, Jana, Page, Matthew J.T., Pekrun, Arnulf, Prader, Seraina, Proietti, Michele, Rajacic, Nada, Rothoeft, Tobias, Ryan, Clodagh, Salou, Sarah, Salzer, Elisabeth, Savic, Sinisa, Schilling, Freimut H., Schönberger, Stefan, Schuetz, Catharina, Schuez-Havupalo, Linnea, Schulte, Björn, Schulz, Ansgar, Schuster, Volker, Seidel, Markus G., Siepermann, Kathrin, Skomska-Pawliszak, Malgorzata, Smisek, Petr, Soomann, Maarja, Stiefel, Martina, Storck, Simone, Strahm, Brigitte, Streiter, Monika, Teltschik, Heiko-Manuel, Thalhammer, Julian, Tippelt, Stephan, Toskov, Vasil, Trück, Johannes, Vieth, Simon, von Bismarck, Philipp, Wegehaupt, Oliver, Wiesel, Thomas, Wittkowski, Helmut, Yalcin Gungoren, Ezgi, Hägele, Pauline, Staus, Paulina, Scheible, Raphael, Uhlmann, Annette, Heeg, Maximilian, Klemann, Christian, Maccari, Maria Elena, Ritterbusch, Henrike, Armstrong, Martin, Cutcutache, Ioana, Elliott, Katherine S, von Bernuth, Horst, Leahy, Timothy Ronan, Leyh, Jörg, Holzinger, Dirk, Lehmberg, Kai, Svec, Peter, Masjosthusmann, Katja, Hambleton, Sophie, Jakob, Marcus, Sparber-Sauer, Monika, Kager, Leo, Puzik, Alexander, Wolkewitz, Martin, Lorenz, Myriam Ricarda, Schwarz, Klaus, Speckmann, Carsten, Rensing-Ehl, Anne ^†, Ehl, Stephan ^{†, *}

Source: In The Lancet Haematology February 2024 11(2):e114-e126

Hematopoietic stem cell transplantation for adolescents and adults with inborn errors of immunity: an EBMT IEWP study

Authors: Aiuti, Alessandro, Maschan, Alexei, Aljurf, Mahmoud, Gedde-Dahl, Tobias, Gurman, Gunhan, Bordon, Victoria, Kriván, Gergely, Locatelli, Franco, Porta, Fulvio, Valcárcel, David, Beguin, Yves, Faraci, Maura, Kröger, Nicolaus, Kulagin, Aleksandr, Shaw, Peter J., Veelken, Joan Hendrik, Diaz de Heredia, Cristina, Fagioli, Franca, Felber, Matthias, Gruhn, Bernd, Holter, Wolfgang, Rössig, Claudia, Sedlacek, Petr, Apperley, Jane, Ayas, Mouhab, Bodova, Ivana, Choi, Goda, Cornelissen, J.J., Sirvent, Anne, Khan, Anjum, Kupesiz, Alphan, Lenhoff, Stig, Ozdogu, Hakan, von der Weid, Nicolas, Rovira, Montserrat, Schots, Rik, Vinh, Donald C., Albert, Michael H., Sirait, Tiarlan, Eikema, Dirk-Jan, Bakunina, Katerina, Wehr, Claudia, Suarez, Felipe, Fox, Maria Laura, Mahlaoui, Nizar, Gennery, Andrew R., Lankester, Arjan C., Beier, Rita, Bernardo, Maria Ester, Bigley, Venetia, Lindemans, Caroline A., Burns, Siobhan O., Carpenter, Ben, Dybko, Jaroslaw, Güngör, Tayfun, Hauck, Fabian, Lum, Su Han, Balashov, Dmitry, Meisel, Roland, Moshous, Despina, Schulz, Ansgar, Speckmann, Carsten, Slatter, Mary A., Strahm, Brigitte, Uckan-Cetinkaya, Duygu, Meyts, Isabelle, Vallée, Tanja C., Wynn, Robert, Neven, Bénédicte, Morris, Emma C.

Source: In Blood 6 October 2022 140(14):1635-1649

Adoptive transfer of ex vivo expanded regulatory T cells improves immune cell engraftment and therapy-refractory chronic GvHD

Authors: Landwehr-Kenzel, Sybille, Müller-Jensen, Leonie, Kuehl, Joern-Sven, Abou-el-Enein, Mohamed, Hoffmann, Henrike, Muench, Sandra, Kaiser, Daniel, Roemhild, Andy, von Bernuth, Horst, Voeller, Mirjam, Schmueck-Henneresse, Michael, Gruhn, Bernd, Stervbo, Ulrik, Babel, Nina, Volk, Hans-Dieter, Reinke, Petra

Source: Molecular therapy. 30(6):2298-2314

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100169696307.0x000001&indx=1&recIds=ETOCvdc_100169696307.0x000001

Two Cases of Veno-occlusive Disease/Sinusoidal Obstruction Syndrome After Thioguanine Treatment for Acute Lymphoblastic Leukemia

Authors: Gruhn, Bernd, Brodt, Grit, Mentzel, Hans-Joachim, Ernst, Jana

Source: Journal of pediatric hematology/oncology. 44(2):e572-e575

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100145615512.0x000001&indx=1&recIds=ETOCvdc_100145615512.0x000001

Extended Treatment With Mesenchymal Stromal Cells-Frankfurt am Main in a Pediatric Patient With Steroid-refractory Acute Gastrointestinal Graft-Versus-Host Disease: Case Report and Review of the Literature

Authors: Gruhn, Bernd, Brodt, Grit, Ernst, Jana

Source: Journal of pediatric hematology/oncology. 43(3):e419-e425

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181807812.0x000001&indx=1&recIds=ETOCvdc_100181807812.0x000001

Targeted busulfan-based reduced-intensity conditioning and HLA-matched HSCT cure hemophagocytic lymphohistiocytosis

Authors: Felber, Matthias, Steward, Colin G., Kentouche, Karim, Fasth, Anders, Wynn, Robert F., Zeilhofer, Ulrike, Haunerdinger, Veronika, Volkmer, Benjamin, Prader, Seraina, Gruhn, Bernd, Ehl, Stephan, Lehmberg, Kai, Müller, Daniel, Gennery, Andrew R., Albert, Michael H., Hauck, Fabian, Rao, Kanchan, Veys, Paul, Hassan, Moustapha, Lankester, Arjan C., Schmid, Jana Pachlopnik, Hauri-Hohl, Mathias M. ^*, Güngör, Tayfun ^*

Source: In Blood Advances 12 May 2020 4(9):1998-2010

Favorable outcomes of hematopoietic stem cell transplantation in children and adolescents with Diamond-Blackfan anemia

Authors: Strahm, Brigitte, Loewecke, Felicia, Niemeyer, Charlotte M., Albert, Michael, Ansari, Marc, Bader, Peter, Bertrand, Yves, Burkhardt, Birgit, Da Costa, Lydie M., Ferster, Alina, Fischer, Alexandra, Güngör, Tayfun, Gruhn, Bernd, Hainmann, Ina, Kapp, Friedrich, Lang, Peter, Müller, Ingo, Schulz, Ansgar, Szvetnik, Amina, Wlodarski, Marcin, Noellke, Peter, Leblanc, Thierry, Dalle, Jean-Hugues

Source: In Blood Advances 28 April 2020 4(8):1760-1769

Identification of miRNAs and associated pathways regulated by Leukemia Inhibitory Factor in trophoblastic cell lines

Authors: Morales-Prieto, Diana M., Barth, Emanuel, Murrieta-Coxca, Jose Martín, Favaro, Rodolfo R., Gutiérrez-Samudio, Ruby N., Chaiwangyen, Wittaya, Ospina-Prieto, Stephanie, Gruhn, Bernd, Schleußner, Ekkehard, Marz, Manja, Markert, Udo R.

Source: In Placenta December 2019 88:20-27

Gonadal Function after Busulfan Compared with Treosulfan in Children and Adolescents Undergoing Allogeneic Hematopoietic Stem Cell Transplant

Authors: Faraci, Maura, Diesch, Tamara, Labopin, Myriam, Dalissier, Arnaud, Lankester, Arian, Gennery, Andrew, Sundin, Mikael, Uckan-Cetinkaya, Duygu, Bierings, Marc, Peters, Anke M.J., Garwer, Martina, Schulz, Ansgar, Michel, Gerard, Giorgiani, Giovanna, Gruhn, Bernd, Locatelli, Franco, Giardino, Stefano, Uyttebroeck, Anne, Rialland, Fanny, Itäla-Remes, Maija, Dreger, Peter, Shaw, Peter J., Bordon, Victoria, Schlegel, Paul G., Mellgren, Karin, Moraleda, Jose M., Patrick, Katharine, Schneider, Pascale, Jubert, Charlotte, Lawitschka, Anita, Salooja, Nina, Basak, Grzegorz W., Corbacioglu, Selim, Duarte, Rafael, Bader, Peter

Source: In Biology of Blood and Marrow Transplantation September 2019 25(9):1786-1791

Solid organ transplantation after hematopoietic stem cell transplantation in childhood: A multicentric retrospective survey

Authors: Faraci, Maura ^*, Bertaina, Alice, Dalissier, Arnaud, Ifversen, Marianne, Schulz, Ansgar, Gennery, Andrew, Burkhardt, Birgit, Badell Serra, Isabel, Diaz-de-Heredia, Cristina, Lanino, Edoardo, Lankester, Arjan C., Gruhn, Bernd, Matthes-Martin, Susanne, Kühl, Joern S., Varotto, Stefania, Paillard, Catherine, Guilmatre, Audrey, Sastre, Ana, Abecasis, Manuel, Garwer, Birgit, Sedlacek, Petr, Boelens, Jaap J., Beohou, Eric, Bader, Peter

Source: In American Journal of Transplantation June 2019 19(6):1798-1805

Viruses and atypical bacteria in the respiratory tract of immunocompromised and immunocompetent patients with airway infection

Authors: Reckziegel, Maria, Weber-Osel, Claudia, Egerer, Renate, Gruhn, Bernd, Kubek, Florian, Walther, Mario, Wilhelm, Stefanie, Zell, Roland, Krumbholz, Andi

Source: European journal of clinical microbiology & infectious diseases. 39(8):1581-1592

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Haploidentical Stem Cell Transplantation for Refractory/Relapsed Neuroblastoma

Authors: Illhardt, Toni, Toporski, Jacek, Feuchtinger, Tobias, Turkiewicz, Dominik, Teltschik, Heiko-Manuel, Ebinger, Martin, Schwarze, Carl-Philipp, Holzer, Ursula, Lode, Holger N., Albert, Michael H., Gruhn, Bernd, Urban, Christian, Dykes, Josefina H., Teuffel, Oliver, Schumm, Michael, Handgretinger, Rupert, Lang, Peter ^*

Source: In Biology of Blood and Marrow Transplantation May 2018 24(5):1005-1012

Mother Donors Improve Outcomes after HLA Haploidentical Transplantation: A Study by the Cellular Therapy and Immunobiology Working Party of the European Society for Blood and Marrow Transplantation

Authors: Ruggeri, Loredana, Eikema, Dirk-Jan, Bondanza, Attilio, Noviello, Maddalena, van Biezen, Anja, de Wreede, Liesbeth C., Crucitti, Lara, Vago, Luca, Ciardelli, Sara, Bader, Peter, Koc, Yener, Locatelli, Franco, Veelken, Joan H., Gruhn, Bernd, Evans, Pamela, Chabannon, Christian, Toubert, Antoine, Velardi, Andrea

Source: In Transplantation and Cellular Therapy April 2022 28(4):206-206

Immunosuppressive Total Nodal Irradiation–Based Reconditioning Regimens After Graft Rejection or Graft Failure in Pediatric Patients Treated With Myeloablative Allogeneic Hematopoietic Cell Transplantation

Authors: Wegener, Daniel, Lang, Peter, Paulsen, Frank, Weidner, Nicola, Zips, Daniel, Ebinger, Martin, Holzer, Ursula, Döring, Michaela, Basu, Oliver, Gruhn, Bernd, Wittig, Andrea, Teltschik, Heiko-Manuel, Handgretinger, Rupert, Heinzelmann, Frank

Source: International journal of radiation oncology, biology, physics. 104(1):137-143

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100092196577.0x000001&indx=1&recIds=ETOCvdc_100092196577.0x000001

Beneficial role of CD8+ T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias: results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting

Authors: Bondanza, Attilio, Ruggeri, Loredana, Noviello, Maddalena, Eikema, Dirk-Jan, Bonini, Chiara, Chabannon, Christian, van der Werf, Steffie, van Biezen, Anja, de Wreede, Liesbeth C., Crucitti, Lara, Vago, Luca, Merluzzi, Mara, Massei, Maria Speranza, Veelken, Hendrik, Koc, Yener, Bader, Peter, Gruhn, Bernd, Locatelli, Franco, Ciceri, Fabio, Toubert, Antoine, Velardi, Andrea

Source: Bone marrow transplantation. 54(6):867-876

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193249844.0x000001&indx=1&recIds=ETOCvdc_100193249844.0x000001

Presence of centromeric but absence of telomeric group B KIR haplotypes in stem cell donors improve leukaemia control after HSCT for childhood ALL

Authors: Babor, Florian, Peters, Christina, Manser, Angela, Glogova, Evgenia, Sauer, Martin, Pötschger, Ulrike, Ahlmann, Martina, Cario, Gunnar, Feuchtinger, Tobias, Gruhn, Bernd, Güngör, Tayfun, Horn, Peter, Kremens, Bernhard, Lang, Peter, Mezger, Markus, Müller, Ingo, Mytilineos, Joannis, Oevermann, Lena, Pichler, Herbert, Scherenschlich, Nadine, Schuster, Friedhelm, Siepermann, Meinolf, Stachel, Daniel, Strahm, Brigitte, Wössmann, Wilhelm, Escherich, Gabriele, Zimmermann, Martin, Schrappe, Martin, Borkhardt, Arndt, Eckert, Cornelia, Bader, Peter, Uhrberg, Markus, Meisel, Roland

Source: Bone marrow transplantation. 54(11):1847-1858

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190895531.0x000001&indx=1&recIds=ETOCvdc_100190895531.0x000001

Allogeneic hematopoietic stem cell transplantation from unrelated donors is associated with higher infection rates in children with acute lymphoblastic leukemia—A prospective international multicenter trial on behalf of the BFM‐SG and the EBMT‐PDWP

Authors: Pichler, Herbert, Lawitschka, Anita, Glogova, Evgenia, Willasch, Andre M., Luettichau, Irene, Lehrnbecher, Thomas, Matthes‐Martin, Susanne, Lang, Peter, Bader, Peter, Sykora, Karl W., Schrum, Johanna, Kremens, Bernhard, Ehlert, Karoline, Albert, Michael H., Kuhlen, Michaela, Meisel, Roland, Guengoer, Tayfun, Strahm, Brigitte, Gruhn, Bernd, Schulz, Ansgar, Woessmann, Wilhelm, Poetschger, Ulrike, Peters, Christina

Source: American journal of hematology. 94(8):880-890

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CTLA-4 polymorphisms: influence on transplant-related mortality and survival in children undergoing allogeneic hematopoietic stem cell transplantation

Authors: Hammrich, Judith, Wittig, Susan, Ernst, Thomas, Gruhn, Bernd

Source: Journal of cancer research and clinical oncology. 144(3):587-592

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100118338293.0x000001&indx=1&recIds=ETOCvdc_100118338293.0x000001