Metabolomic profiles in Jamaican children with and without autism spectrum disorder

Authors: Yazdani, Akram, Samms-Vaughan, Maureen, Saroukhani, Sepideh, Bressler, Jan, Hessabi, Manouchehr, Tahanan, Amirali, Grove, Megan L., Gangnus, Tanja, Putluri, Vasanta, Kamal, Abu Hena Mostafa, Putluri, Nagireddy, Loveland, Katherine A., Rahbar, Mohammad H.

Subject Terms: Quantitative Biology - Biomolecules

Access URL: http://arxiv.org/abs/2403.07147

Interactive associations of eczema with glutathione S-transferase genes in relation to autism spectrum disorder and its severity in Jamaican children

Authors: Saroukhani, Sepideh, Samms-Vaughan, Maureen, Bressler, Jan, Lee, MinJae, Byrd-Williams, Courtney, Hessabi, Manouchehr, Grove, Megan L., Shakespeare-Pellington, Sydonnie, Loveland, Katherine A., Rahbar, Mohammad H.

Source: In Research in Autism Spectrum Disorders July 2023 105

Are there sex differences in interactive associations of environmental exposure to Lead (Pb), Mercury (Hg), and Manganese (Mn) with GST Genes (GSTP1, GSTT1, and GSTM1) in relation to ASD in Jamaican children?

Authors: Zwiya, Hiba T., Samms-Vaughan, Maureen, Bressler, Jan, Lee, MinJae, Byrd-Williams, Courtney, Hessabi, Manouchehr, Grove, Megan L., Shakespeare-Pellington, Sydonnie, Loveland, Katherine A., Rahbar, Mohammad H.

Source: In Research in Autism Spectrum Disorders July 2023 105

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Interaction of Blood Manganese Concentrations with 'GSTT1' in Relation to Autism Spectrum Disorder in Jamaican Children

Authors: Rahbar, Mohammad H. (ORCID 0000-0003-4608-9445), Samms-Vaughan, Maureen, Saroukhani, Sepideh, Lee, MinJae, Zhang, Jing, Bressler, Jan, Hessabi, Manouchehr, Shakespeare-Pellington, Sydonnie, Grove, Megan L., Loveland, Katherine A.

Source: Journal of Autism and Developmental Disorders. Jun 2021 51(6):1953-1965.

Peer Reviewed: Y

Page Count: 13

Sponsoring Agency: National Institute of Environmental Health Sciences (NIEHS) (NIH)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (NIH)
National Institutes of Health (DHHS), Fogarty International Center
National Center for Advancing Translational Sciences (NCATS) (NIH), Clinical and Translational Science Awards (CTSA) Program

Descriptors: Physiology, Autism, Pervasive Developmental Disorders, Foreign Countries, Socioeconomic Status, Interaction, Genetics

Geographic Terms: Jamaica

Longitudinal change in blood DNA epigenetic signature after smoking cessation

Authors: Keshawarz, Amena, Joehanes, Roby, Guan, Weihua, Huan, Tianxiao, DeMeo, Dawn L., Grove, Megan L., Fornage, Myriam, Levy, Daniel, O'Connor, George

Source: Epigenetics. 17(10):1098-1109

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165283681.0x000001&indx=1&recIds=ETOCvdc_100165283681.0x000001

DNA Methylation Profile in Buffy Coat Identifies Methylation Differences Between Cirrhosis with and Without Hepatocellular Carcinoma.

Authors: Lim, Hyeyeun, El-Serag, Hashem B., Luster, Michelle, Grove, Megan L., Byun, Jinyoung, Jung, Yuri, Han, Younghun, Boerwinkle, Eric, Amos, Christopher I., Thrift, Aaron P.

Source: Cancers; Jan2025, Vol. 17 Issue 2, p266, 14p

Subject Terms: RISK assessment, CIRRHOSIS of the liver, SECONDARY analysis, GENOME-wide association studies, RESEARCH funding, EARLY detection of cancer, EPIGENOMICS, TUMOR markers, DESCRIPTIVE statistics, DNA methylation, CANCER genes, CONFIDENCE intervals, HEPATOCELLULAR carcinoma

Perinatal Factors Associated with Autism Spectrum Disorder in Jamaican Children

Authors: Saroukhani, Sepideh, Samms-Vaughan, Maureen, Lee, MinJae, Bach, MacKinsey A., Bressler, Jan, Hessabi, Manouchehr, Grove, Megan L., Shakespeare-Pellington, Sydonnie, Loveland, Katherine A., Rahbar, Mohammad H.

Source: Journal of Autism and Developmental Disorders. Sep 2020 50(9):3341-3357.

Peer Reviewed: Y

Page Count: 17

Sponsoring Agency: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (NIH)
National Institutes of Health (DHHS), Fogarty International Center
National Institute of Environmental Health Sciences (NIEHS) (NIH)
National Center for Advancing Translational Sciences (NCATS) (NIH), Clinical and Translational Science Awards (CTSA) Program
National Center for Research Resources (NIH/DHHS)
National Center for Advancing Translational Sciences (NCATS) (DHHS/NIH)

Descriptors: Foreign Countries, Perinatal Influences, Autism, Pervasive Developmental Disorders, Young Children, Place of Residence, Birth, Correlation, Body Weight, Premature Infants, Socioeconomic Status

Geographic Terms: Jamaica

Association of mitochondrial DNA copy number with cardiometabolic diseases

Authors: Liu, Xue, Longchamps, Ryan J., Wiggins, Kerri L., Raffield, Laura M., Bielak, Lawrence F., Zhao, Wei, Pitsillides, Achilleas, Blackwell, Thomas W., Yao, Jie, Guo, Xiuqing, Kurniansyah, Nuzulul, Thyagarajan, Bharat, Pankratz, Nathan, Rich, Stephen S., Taylor, Kent D., Peyser, Patricia A., Heckbert, Susan R., Seshadri, Sudha, Cupples, L. Adrienne, Boerwinkle, Eric, Grove, Megan L., Larson, Nicholas B., Smith, Jennifer A., Vasan, Ramachandran S., Sofer, Tamar, Fitzpatrick, Annette L., Fornage, Myriam, Ding, Jun, Correa, Adolfo, Abecasis, Goncalo, Psaty, Bruce M., Wilson, James G., Levy, Daniel, Rotter, Jerome I., Bis, Joshua C., Satizabal, Claudia L., Arking, Dan E., Liu, Chunyu

Source: In Cell Genomics 13 October 2021 1(1)

Epigenome-wide association study of mitochondrial genome copy number

Authors: Wang, Penglong, Castellani, Christina A, Yao, Jie, Huan, Tianxiao, Bielak, Lawrence F, Zhao, Wei, Haessler, Jeffrey, Joehanes, Roby, Sun, Xianbang, Guo, Xiuqing, Longchamps, Ryan J, Manson, JoAnn E, Grove, Megan L, Bressler, Jan, Taylor, Kent D, Lappalainen, Tuuli, Kasela, Silva, Van Den Berg, David J, Hou, Lifang, Reiner, Alexander, Liu, Yongmei, Boerwinkle, Eric, Smith, Jennifer A, Peyser, Patricia A, Fornage, Myriam, Rich, Stephen S, Rotter, Jerome I, Kooperberg, Charles, Arking, Dan E, Levy, Daniel, Liu, Chunyu

Source: Human molecular genetics. 31(2):309-319

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138792875.0x000001&indx=1&recIds=ETOCvdc_100138792875.0x000001

Correlation between concentrations of four heavy metals in cord blood and childhood blood of Jamaican children

Authors: Rahbar, Mohammad H., Samms-Vaughan, Maureen, Hessabi, Manouchehr, Bressler, Jan, Gillani, Shezeen, Grove, Megan L., Shakspeare-Pellington, Sydonnie, Loveland, Katherine A.

Source: Journal of environmental science and health.Part A.Toxic/hazardous substances & environmental engineering. 56(11):1196-1205

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135458083.0x000001&indx=1&recIds=ETOCvdc_100135458083.0x000001

Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome‐wide association study in over 12, 000 non‐demented participants

Authors: Damotte, Vincent, Lee, Sven J., Chouraki, Vincent, Grenier‐Boley, Benjamin, Simino, Jeannette, Adams, Hieab, Tosto, Giuseppe, White, Charles, Terzikhan, Natalie, Cruchaga, Carlos, Knol, Maria J., Li, Shuo, Schraen, Susanna, Grove, Megan L., Satizabal, Claudia, Amin, Najaf, Berr, Claudine, Younkin, Steven, Gottesman, Rebecca F., Buée, Luc, Beiser, Alexa, Knopman, David S., Uitterlinden, Andre, DeCarli, Charles, Bressler, Jan, DeStefano, Anita, Dartigues, Jean‐François, Yang, Qiong, Boerwinkle, Eric, Tzourio, Christophe, Fornage, Myriam, Ikram, M. Arfan, Amouyel, Philippe, Jager, Phil, Reitz, Christiane, Mosley, Thomas H., Lambert, Jean‐Charles, Seshadri, Sudha, Duijn, Cornelia M.

Source: Alzheimer's & dementia. 17(10):1663-1674

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132494133.0x000001&indx=1&recIds=ETOCvdc_100132494133.0x000001

Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality

Authors: Schunk, Stefan J, Kleber, Marcus E, März, Winfried, Pang, Shichao, Zewinger, Stephen, Triem, Sarah, Ege, Philipp, Reichert, Matthias C, Krawczyk, Marcin, Weber, Susanne N, Jaumann, Isabella, Schmit, David, Sarakpi, Tamim, Wagenpfeil, Stefan, Kramann, Rafael, Boerwinkle, Eric, Ballantyne, Christie M, Grove, Megan L, Tragante, Vinicius, Pilbrow, Anna P, Richards, A Mark, Cameron, Vicky A, Doughty, Robert N, Dubé, Marie-Pierre, Tardif, Jean-Claude, Feroz-Zada, Yassamin, Sun, Maxine, Liu, Chang, Ko, Yi-An, Quyyumi, Arshed A, Hartiala, Jaana A, Tang, W H Wilson, Hazen, Stanley L, Allayee, Hooman, McDonough, Caitrin W, Gong, Yan, Cooper-DeHoff, Rhonda M, Johnson, Julie A, Scholz, Markus, Teren, Andrej, Burkhardt, Ralph, Martinsson, Andreas, Smith, J Gustav, Wallentin, Lars, James, Stefan K, Eriksson, Niclas, White, Harvey, Held, Claes, Waterworth, Dawn, Trompet, Stella, Jukema, J Wouter, Ford, Ian, Stott, David J, Sattar, Naveed, Cresci, Sharon, Spertus, John A, Campbell, Hannah, Tierling, Sascha, Walter, Jörn, Ampofo, Emmanuel, Niemeyer, Barbara A, Lipp, Peter, Schunkert, Heribert, Böhm, Michael, Koenig, Wolfgang, Fliser, Danilo, Laufs, Ulrich, Speer, Thimoteus

Source: European heart journal. 42(18):1742-1756

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121461779.0x000001&indx=1&recIds=ETOCvdc_100121461779.0x000001

Mitochondrial heteroplasmy improves risk prediction for myeloid neoplasms.

Authors: Hong, Yun Soo, Pasca, Sergiu, Shi, Wen, Puiu, Daniela, Lake, Nicole J., Lek, Monkol, Ru, Meng, Grove, Megan L., Prizment, Anna, Joshu, Corinne E., Platz, Elizabeth A., Guallar, Eliseo, Arking, Dan E., Gondek, Lukasz P.

Source: Nature Communications; 11/22/2024, Vol. 15 Issue 1, p1-15, 15p

Subject Terms: DISEASE risk factors, MITOCHONDRIAL DNA, HEMATOLOGIC malignancies, TUMORS, BIOMARKERS

A Genome-wide Association Study Discovers 46 Loci of the Human Metabolome in the Hispanic Community Health Study/Study of Latinos

Authors: Feofanova, Elena V., Chen, Han, Dai, Yulin, Jia, Peilin, Grove, Megan L., Morrison, Alanna C., Qi, Qibin, Daviglus, Martha, Cai, Jianwen, North, Kari E., Laurie, Cathy C., Kaplan, Robert C., Boerwinkle, Eric, Yu, Bing

Source: In The American Journal of Human Genetics 5 November 2020 107(5):849-863

Interaction between a mixture of heavy metals (lead, mercury, arsenic, cadmium, manganese, aluminum) and GSTP1, GSTT1, and GSTM1 in relation to autism spectrum disorder

Authors: Rahbar, Mohammad H. ^*, Samms-Vaughan, Maureen, Lee, MinJae, Zhang, Jing, Hessabi, Manouchehr, Bressler, Jan, Bach, MacKinsey A., Grove, Megan L., Shakespeare-Pellington, Sydonnie, Beecher, Compton, McLaughlin, Wayne, Loveland, Katherine A.

Source: In Research in Autism Spectrum Disorders November 2020 79

Association of polychlorinated biphenyls and organochlorine pesticides with autism spectrum disorder in Jamaican children

Authors: Bach, MacKinsey A., Samms-Vaughan, Maureen, Hessabi, Manouchehr, Bressler, Jan, Lee, MinJae, Zhang, Jing, Shakespeare-Pellington, Sydonnie, Grove, Megan L., Loveland, Katherine A., Rahbar, Mohammad H. ^*

Source: In Research in Autism Spectrum Disorders August 2020 76

Serum sphingolipids and incident diabetes in a US population with high diabetes burden: the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Authors: Chen, Guo-Chong, Chai, Jin Choul, Yu, Bing, Michelotti, Gregory A, Grove, Megan L, Fretts, Amanda M, Daviglus, Martha L, Garcia-Bedoya, Olga L, Thyagarajan, Bharat, Schneiderman, Neil, Cai, Jianwen, Kaplan, Robert C, Boerwinkle, Eric, Qi, Qibin ^*

Source: In The American Journal of Clinical Nutrition July 2020 112(1):57-65

Multiple SCN5A variant enhancers modulate its cardiac gene expression and the QT interval

Authors: Kapoor, Ashish, Lee, Dongwon, Zhu, Luke, Soliman, Elsayed Z., Grove, Megan L., Boerwinkle, Eric, Arking, Dan E., Chakravarti, Aravinda

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 May . 116(22), 10636-10645.

Access URL: https://www.jstor.org/stable/26707125

Maternal Exposures Associated with Autism Spectrum Disorder in Jamaican Children

Authors: Christian, MacKinsey A., Samms-Vaughan, Maureen, Lee, MinJae, Bressler, Jan, Hessabi, Manouchehr, Grove, Megan L., Shakespeare-Pellington, Sydonnie, Coore Desai, Charlene, Reece, Jody-Ann, Loveland, Katherine A., Boerwinkle, Eric, Rahbar, Mohammad H.

Source: Journal of Autism and Developmental Disorders. Aug 2018 48(8):2766-2778.

Peer Reviewed: Y

Page Count: 13

Sponsoring Agency: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (NIH)
National Institute of Environmental Health Sciences (NIEHS) (NIH)
National Center for Research Resources (NIH/DHHS)
National Center for Advancing Translational Sciences (NCATS) (DHHS/NIH)

Descriptors: Autism, Pervasive Developmental Disorders, Pregnancy, Correlation, Mothers, Hazardous Materials, Nutrition, Diseases, Prenatal Influences, Case Studies, Control Groups, Matched Groups, Regression (Statistics), Trauma, Foreign Countries, Children

Geographic Terms: Jamaica