Somatic Genomic Alterations in Haematological Tumours Can Interfere With Accurate HLA and Chimerism Diagnostics.

Authors: Olieslagers, Timo I.^1,2 (AUTHOR) timo.olieslagers@mumc.nl, Groeneweg, Mathijs^1,2 (AUTHOR), van Gorkom, Gwendolyn N. Y.^2,3 (AUTHOR), Beckers, Erik A. M.³ (AUTHOR), Wieten, Lotte^1,2 (AUTHOR), Voorter, Christina E. M.^1,2 (AUTHOR)

Source: HLA: Immune Response Genetics. Mar2025, Vol. 105 Issue 3, p1-14. 14p.

Polymorphic differences within HLA‐C alleles contribute to alternatively spliced transcripts lacking exon 5

Authors: Ehlers, Femke A. I., Olieslagers, Timo I., Groeneweg, Mathijs, Bos, Gerard M. J., Tilanus, Marcel G. J., Voorter, Christina E. M., Wieten, Lotte

Source: HLA. 100(3):232-243

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Long-Read Nanopore Sequencing Validated for Human Leukocyte Antigen Class I Typing in Routine Diagnostics

Authors: Matern, Benedict M., Olieslagers, Timo I., Groeneweg, Mathijs, Duygu, Burcu, Wieten, Lotte, Tilanus, Marcel G.J., Voorter, Christina E.M.

Source: In The Journal of Molecular Diagnostics July 2020 22(7):912-919

Polymorphism clustering of the 21.5 kb DPA‐promoter‐DPB region reveals novel extended full‐length haplotypes

Authors: Truong, Linh, Matern, Ben M., Groeneweg, Mathijs, D'Orsogna, Lloyd, Martinez, Patricia, Tilanus, Marcel G. J., De Santis, Dianne

Source: HLA. 96(3):299-311

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Insights into the polymorphism in HLA‐DRA and its evolutionary relationship with HLA haplotypes

Authors: Matern, Ben M., Olieslagers, Timo I., Voorter, Christina E. M., Groeneweg, Mathijs, Tilanus, Marcel G. J.

Source: HLA. 95(2):117-127

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099857043.0x000001&indx=1&recIds=ETOCvdc_100099857043.0x000001

Full-length extension of HLA allele sequences by HLA allele-specific hemizygous Sanger sequencing (SSBT)

Authors: Voorter, Christina E.M., Matern, Ben, Tran, Thuong Hien, Fink, Annette, Vidan-Jeras, Blanka, Montanic, Sendi, Fischer, Gottfried, Fae, Ingrid, de Santis, Dianne, Whidborne, Rebecca, Andreani, Marco, Testi, Manuela, Groeneweg, Mathijs, Tilanus, Marcel G.J.

Source: In Human Immunology November 2018 79(11):763-772

The 18th International HLA & Immunogenetics workshop project report: Creating fully representative MHC reference haplotypes.

Authors: Pollock, Nicholas R., Farias, Ticiana D. J., Kichula, Katherine M., Sauter, Jürgen, Scholz, Stephan, Nii‐Trebi, Nicholas I., Khor, Seik‐Soon, Tokunaga, Katsushi, Voorter, Christina E., Groeneweg, Mathijs, Augusto, Danillo G., Arrieta‐Bolaños, Esteban, Mayor, Neema P., Edinur, Hisham Atan, ElGhazali, Gehad, Issler, Hellen C., Petzl‐Erler, Maria Luiza, Oksenberg, Jorge R., Marin, Wesley M., Hollenbach, Jill A.

Source: HLA: Immune Response Genetics; Jun2024, Vol. 103 Issue 6, p1-8, 8p

Subject Terms: MAJOR histocompatibility complex, IMMUNOGENETICS, HAPLOTYPES, LIFE sciences, GENE libraries, NUCLEOTIDE sequencing

Uncommon HLA alleles identified by hemizygous ultra-high Sanger sequencing: haplotype associations and reconsideration of their assignment in the Common and Well-Documented catalogue

Authors: Voorter, Christina E.M., Groeneweg, Mathijs, Groeneveld, Lisette, Tilanus, Marcel G.J.

Source: In Human Immunology February 2016 77(2):184-190

Resolving unknown nucleotides in the IPD-IMGT/HLA database by extended and full-length sequencing of HLA class I and II alleles.

Authors: Voorter, Christina E. M.^1,2 (AUTHOR) c.voorter@mumc.nl, Groeneweg, Mathijs^1,2 (AUTHOR), Olieslagers, Timo I.^1,2 (AUTHOR), Fae, Ingrid³ (AUTHOR), Fischer, Gottfried F.³ (AUTHOR), Andreani, Marco⁴ (AUTHOR), Troiano, Maria⁴ (AUTHOR), Vidan-Jeras, Blanka⁵ (AUTHOR), Montanic, Sendi⁵ (AUTHOR), Hepkema, Bouke G.⁶ (AUTHOR), Bungener, Laura B.⁶ (AUTHOR), Tilanus, Marcel G. J.^1,2 (AUTHOR), Wieten, Lotte^1,2 (AUTHOR)

Source: Immunogenetics. Apr2024, Vol. 76 Issue 2, p109-121. 13p.

Subject Terms: *DATABASES, *ALLELES, *NUCLEOTIDES, *GENETIC code, *PEPTIDES, *OBJECT tracking (Computer vision)

Minimum information for reporting next generation sequence genotyping (MIRING): Guidelines for reporting HLA and KIR genotyping via next generation sequencing

Authors: Mack, Steven J., Milius, Robert P., Gifford, Benjamin D., Sauter, Jürgen, Hofmann, Jan, Osoegawa, Kazutoyo, Robinson, James, Groeneweg, Mathijs, Turenchalk, Gregory S., Adai, Alex, Holcomb, Cherie, Rozemuller, Erik H., Penning, Maarten T., Heuer, Michael L., Wang, Chunlin, Salit, Marc L., Schmidt, Alexander H., Parham, Peter R., Müller, Carlheinz, Hague, Tim, Fischer, Gottfried, Fernandez-Viňa, Marcelo, Hollenbach, Jill A., Norman, Paul J., Maiers, Martin

Source: In Human Immunology December 2015 76(12):954-962

Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function

Authors: Bermudez, Beatriz, Dahl, Tuva Borresdatter, Medina, Indira, Groeneweg, Mathijs, Holm, Sverre, Montserrat-de la Paz, Sergio, Rousch, Mat, Otten, Jeroen, Herias, Veronica, Varela, Lourdes M., Ranheim, Trine, Yndestad, Arne, Ortega-Gomez, Almudena, Abia, Rocio, Nagy, Laszlo, Aukrust, Pal, Muriana, Francisco J.G., Halvorsen, Bente, Biessen, Erik Anna Leonardus

Source: Arteriosclerosis, thrombosis, and vascular biology. 37(6):1157-1167

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100049649247.0x000001&indx=1&recIds=ETOCvdc_100049649247.0x000001

Allorecognition of HLA-DP by CD4+ T cells is affected by polymorphism in its alpha chain

Authors: Lauterbach, Nina, Crivello, Pietro, Wieten, Lotte, Zito, Laura, Groeneweg, Mathijs, Voorter, Christina E.M., Fleischhauer, Katharina, Tilanus, Marcel G.J.

Source: In Molecular Immunology May 2014 59(1):19-29

A comprehensive overview of FCGR3A gene variability by full-length gene sequencing including the identification of V158F polymorphism

Authors: Mahaweni, Niken M., Olieslagers, Timo I., Rivas, Ivan Olivares, Molenbroeck, Stefan J. J., Groeneweg, Mathijs, Bos, Gerard M. J., Tilanus, Marcel G. J., Voorter, Christina E. M., Wieten, Lotte

Source: Scientific reports. 8(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131115058.0x000001&indx=1&recIds=ETOCvdc_100131115058.0x000001

Modification of LDL with oxidized 1-palmitoyl-2-arachidonoyl- sn-glycero-3-phosphorylcholine (oxPAPC) results in a novel form of minimally modified LDL that modulates gene expression in macrophages

Authors: Groeneweg, Mathijs, Vergouwe, Monique N., Scheffer, Peter G., Vermue, Hendrikus P.A., Sollewijn Gelpke, Maarten D., Sijbers, Anneke M., Leitinger, Norbert, Hofker, Marten H., de Winther, Menno P.J.

Source: In BBA - Molecular and Cell Biology of Lipids 2008 1781(6):336-343

Lipopolysaccharide-induced gene expression in murine macrophages is enhanced by prior exposure to oxLDL

Authors: Groeneweg, Mathijs ^*, Kanters, Edwin, Vergouwe, Monique N. ^*, Duerink, Hilde ^*, Kraal, Georg, Hofker, Marten H. ^*, de Winther, Menno P.J. ^*

Source: In Journal of Lipid Research October 2006 47(10):2259-2267

Species-Specific Functioning of the Pseudomonas XcpQ Secretin: Role for the C-Terminal Homology Domain and Lipopolysaccharide.

Authors: Bitter, Wilbert, Boxtel, Ria van, Groeneweg, Mathijs

Source: Journal of Bacteriology; April 2007, Vol. 189 Issue 8, p2967-2975, 9p

HLA Class I Molecules as Immune Checkpoints for NK Cell Alloreactivity and Anti-Viral Immunity in Kidney Transplantation.

Authors: Duygu, Burcu, Olieslagers, Timo I., Groeneweg, Mathijs, Voorter, Christina E. M., Wieten, Lotte

Source: Frontiers in Immunology; 7/6/2021, Vol. 12, p1-23, 23p

Subject Terms: IMMUNE checkpoint proteins, ALLOIMMUNITY, KILLER cells, KIDNEY transplantation, GRAFT rejection, CELL receptors, HISTOCOMPATIBILITY antigens

P046 Characterization of novel single-nucleotide polymorphisms in the promoter of HLA-DP region

Authors: Truong, Linh, Matern, Benedict, Groeneweg, Mathijs, Tilanus, Marcel G., D'Orsogna, Lloyd, Martinez, Patricia, De Santis, Dianne

Source: Human immunology. 80(S):88-88

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097389136.0x000001&indx=1&recIds=ETOCvdc_100097389136.0x000001

P060 HLA-DRA polymorphism defines multiple lineages of DRB1*13∼DRB3∼DQB1 haplotypes

Authors: Matern, Benedict, Olieslagers, Timo, Voorter, Christina, Groeneweg, Mathijs, Tilanus, Marcel G.

Source: Human immunology. 80(S):98-98

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100092109157.0x000001&indx=1&recIds=ETOCvdc_100092109157.0x000001

OR25. The highly polymorphic HLA-DRA Gene: conserved and diverse regions within the HLA-DRA gene imply haplotypes of DRA∼DRB3/4/5∼DRB1∼DQB1

Authors: Matern, Benedict M., Olieslagers, Timo I., de Rooij, Laura, Voorter, Christien E., Groeneweg, Mathijs, Tilanus, Marcel G.

Source: Human immunology. 79(S):30-30

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100081651788.0x000001&indx=1&recIds=ETOCvdc_100081651788.0x000001