Prenatal Hyperhomocysteinemia Leads to Synaptic Dysfunction and Structural Alterations in the CA1 Hippocampus of Rats.

Authors: Postnikova, Tatyana Y.¹ (AUTHOR) tapost2@mail.ru, Griflyuk, Alexandra V.¹ (AUTHOR), Tumanova, Natalia L.¹ (AUTHOR), Dubrovskaya, Nadezhda M.¹ (AUTHOR), Mikhel, Anastasia V.¹ (AUTHOR), Vasilev, Dmitriy S.¹ (AUTHOR) dvasilyev@bk.ru, Zaitsev, Aleksey V.¹ (AUTHOR)

Source: Biomolecules (2218-273X). Feb2025, Vol. 15 Issue 2, p305. 18p.

Subject Terms: *POSTSYNAPTIC potential, *WESTERN immunoblotting, *PYRAMIDAL neurons, *SYNAPTIC vesicles, *FETAL development, *NEURAL transmission

Animal Models of Febrile Seizures: Limitations and Recent Advances in the Field.

Authors: Griflyuk, Alexandra V.¹ (AUTHOR) griflyuk.al@mail.ru, Postnikova, Tatyana Y.¹ (AUTHOR), Zaitsev, Aleksey V.¹ (AUTHOR) aleksey_zaitsev@mail.ru

Source: Cells (2073-4409). Nov2024, Vol. 13 Issue 22, p1895. 28p.

Subject Terms: *FEBRILE seizures, *NEURAL development, *ANIMAL models for aging, *NERVOUS system, *NEUROLOGICAL disorders

Alterations in Rat Hippocampal Glutamatergic System Properties after Prolonged Febrile Seizures.

Authors: Griflyuk, Alexandra V.¹ (AUTHOR) griflyuk.al@mail.ru, Postnikova, Tatyana Y.¹ (AUTHOR), Malkin, Sergey L.¹ (AUTHOR), Zaitsev, Aleksey V.¹ (AUTHOR) aleksey_zaitsev@mail.ru

Source: International Journal of Molecular Sciences. Dec2023, Vol. 24 Issue 23, p16875. 15p.

Subject Terms: *FEBRILE seizures, *CENTRAL nervous system, *HIPPOCAMPUS (Brain), *HINDLIMB, *VAGUS nerve, *RATS, *PYRAMIDAL neurons

Febrile Seizures Cause a Rapid Depletion of Calcium-Permeable AMPA Receptors at the Synapses of Principal Neurons in the Entorhinal Cortex and Hippocampus of the Rat.

Authors: Postnikova, Tatyana Y.¹ (AUTHOR) tapost2@mail.ru, Griflyuk, Alexandra V.¹ (AUTHOR), Zhigulin, Arseniy S.¹ (AUTHOR), Soboleva, Elena B.¹ (AUTHOR), Barygin, Oleg I.¹ (AUTHOR), Amakhin, Dmitry V.¹ (AUTHOR), Zaitsev, Aleksey V.¹ (AUTHOR) aleksey_zaitsev@mail.ru

Source: International Journal of Molecular Sciences. Aug2023, Vol. 24 Issue 16, p12621. 15p.

Subject Terms: *FEBRILE seizures, *AMPA receptors, *NEURONS, *HIPPOCAMPUS (Brain), *ENTORHINAL cortex, *SYNAPSES

Prolonged Febrile Seizures Impair Synaptic Plasticity and Alter Developmental Pattern of Glial Fibrillary Acidic Protein (GFAP)-Immunoreactive Astrocytes in the Hippocampus of Young Rats.

Authors: Griflyuk, Alexandra V.¹ (AUTHOR), Postnikova, Tatyana Y.¹ (AUTHOR), Zaitsev, Aleksey V.¹ (AUTHOR) aleksey_zaitsev@mail.ru

Source: International Journal of Molecular Sciences. Oct2022, Vol. 23 Issue 20, p12224-N.PAG. 16p.

Subject Terms: *GLIAL fibrillary acidic protein, *FEBRILE seizures, *NEUROPLASTICITY, *ASTROCYTES, *HIPPOCAMPUS (Brain), *LONG-term potentiation, *GLYCINE receptors

Antiepileptogenic Effects of Anakinra, Lamotrigine and Their Combination in a Lithium–Pilocarpine Model of Temporal Lobe Epilepsy in Rats.

Authors: Zubareva, Olga E., Sinyak, Denis S., Kalita, Alisa D., Griflyuk, Alexandra V., Diespirov, Georgy P., Postnikova, Tatiana Y., Zaitsev, Aleksey V.

Source: International Journal of Molecular Sciences; Oct2023, Vol. 24 Issue 20, p15400, 22p

Subject Terms: TEMPORAL lobe epilepsy, ANAKINRA, VAGUS nerve, SOCIAL anxiety, LAMOTRIGINE, SEIZURES (Medicine), CURIOSITY, BRAIN injuries

Alterations in the Properties of the Rat Hippocampus Glutamatergic System in the Lithium-Pilocarpine Model of Temporal Lobe Epilepsy.

Authors: Diespirov, Georgy P., Postnikova, Tatyana Y., Griflyuk, Alexandra V., Kovalenko, Anna A., Zaitsev, Aleksey V.

Source: Biochemistry (00062979); Mar2023, Vol. 88 Issue 3, p353-363, 11p

Subject Terms: TEMPORAL lobe epilepsy, EXCITATORY postsynaptic potential, NERVOUS system, HINDLIMB, PILOCARPINE, HIPPOCAMPUS (Brain), PATHOLOGICAL physiology, AMPA receptors

Early Life Febrile Seizures Impair Hippocampal Synaptic Plasticity in Young Rats.

Authors: Postnikova, Tatyana Y.¹ (AUTHOR) tapost2@mail.ru, Griflyuk, Alexandra V.¹ (AUTHOR), Amakhin, Dmitry V.¹ (AUTHOR), Kovalenko, Anna A.¹ (AUTHOR), Soboleva, Elena B.¹ (AUTHOR), Zubareva, Olga E.¹ (AUTHOR), Zaitsev, Aleksey V.¹ (AUTHOR) aleksey_zaitsev@mail.ru

Source: International Journal of Molecular Sciences. Aug2021, Vol. 22 Issue 15, p8218-8218. 1p.

Subject Terms: *FEBRILE seizures, *NEUROPLASTICITY, *DENTATE gyrus, *NEUROLOGICAL disorders, *LONG-term potentiation, *GLYCINE receptors, *HEAT stroke

Administration of Bacterial Lipopolysaccharide during Early Postnatal Ontogenesis Induces Transient Impairment of Long-Term Synaptic Plasticity Associated with Behavioral Abnormalities in Young Rats.

Authors: Postnikova, Tatyana Y.¹ (AUTHOR) tapost2@mail.ru, Griflyuk, Alexandra V.¹ (AUTHOR), Ergina, Julia L.¹ (AUTHOR), Zubareva, Olga E.¹ (AUTHOR), Zaitsev, Aleksey V.¹ (AUTHOR) aleksey_zaitsev@mail.ru

Source: Pharmaceuticals (14248247). Mar2020, Vol. 13 Issue 3, p48. 1p.

Subject Terms: *NEUROPLASTICITY, *GLUTAMATE receptors, *ONTOGENY, *NEURAL transmission, *LONG-term potentiation, *RATS, *LONG-term synaptic depression, *LIPOPOLYSACCHARIDES

MTEP, a Selective mGluR5 Antagonist, Had a Neuroprotective Effect but Did Not Prevent the Development of Spontaneous Recurrent Seizures and Behavioral Comorbidities in the Rat Lithium–Pilocarpine Model of Epilepsy.

Authors: Dyomina, Alexandra V., Kovalenko, Anna A., Zakharova, Maria V., Postnikova, Tatiana Yu., Griflyuk, Alexandra V., Smolensky, Ilya V., Antonova, Irina V., Zaitsev, Aleksey V.

Source: International Journal of Molecular Sciences; Jan2022, Vol. 23 Issue 1, p497, 1p

Subject Terms: EXCITATORY amino acids, GLUTAMATE receptors, HYPERKINESIA, EPILEPSY, SEIZURES (Medicine), BRAIN diseases