Exhaled breath particles as a novel tool to study lipid composition of epithelial lining fluid from the distal lung

Authors: Per Larsson, Olaf Holz, Grielof Koster, Anthony Postle, Anna-Carin Olin, Jens M. Hohlfeld

Source: BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-8 (2023)

Subject Terms: Airway inflammation, Endotoxin challenge, LPS, Human experimental exposure, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2466

Access URL: https://doaj.org/article/c6ba4ea50d7d4ddcbd54073ea31ecd63

Oxidative stress, redox status and surfactant metabolism in mechanically ventilated patients receiving different approaches to oxygen therapy (MecROX): An observational study protocol for mechanistic evaluation [version 2; peer review: 2 approved]

Authors: Ahilanandan Dushianthan, Paul Mouncey, Daniel Martin, Lamprini Lampro, Tasnin Shahid, Victoria Goss, Amelia Francis Johnson, William Herbert, Angelica Cazley, Mark Lamond, William Jones, Karen Salmon, Florence Neyroud, Magdalena Minnion, Julian Lentaigne, Grielof Koster, Madhuri Panchal, Anthony D Postle, Helen Moyses, Michael P W Grocott, Martin Feelisch

Source: NIHR Open Research, Vol 4 (2024)

Subject Terms: Oxygen, Hyperoxia, Mechanical ventilation, Surfactant, Redox, Oxidative stress, eng, Medicine

File Description: electronic resource

Relation: https://openresearch.nihr.ac.uk/articles/4-23/v2; https://doaj.org/toc/2633-4402

Access URL: https://doaj.org/article/2d78ef0bea914040a6d45e0af39db2f2

In Vivo Cellular Phosphatidylcholine Kinetics of CD15+ Leucocytes and CD3+ T-Lymphocytes in Adults with Acute Respiratory Distress Syndrome

Authors: Ahilanandan Dushianthan, Rebecca Cusack, Victoria Goss, Grielof Koster, Michael P. W. Grocott, Anthony D. Postle

Source: Cells, Vol 13, Iss 4, p 332 (2024)

Subject Terms: ARDS, neutrophil, lymphocyte, phospholipids, phosphatidylcholine, methyl-D9-choline, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/13/4/332; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/7400a7d26f4e4631915b024263a69675

Mass spectrometry imaging of phosphatidylcholine metabolism in lungs administered with therapeutic surfactants and isotopic tracers

Authors: Shane R. Ellis, Emily Hall, Madhuriben Panchal, Bryn Flinders, Jens Madsen, Grielof Koster, Ron.M.A. Heeren, Howard W. Clark, Anthony D. Postle

Source: Journal of Lipid Research, Vol 62, Iss , Pp 100023- (2021)

Subject Terms: Pulmonary surfactant, lipids, isotope labeling, matrix-assisted laser desorption/ionization, remodeling, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227521000031; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/39a071a8396f4653aeda60ee0dbd835f

Metabolism of a synthetic compared with a natural therapeutic pulmonary surfactant in adult mice

Authors: Jens Madsen, Madhuriben H. Panchal, Rose-Marie A. Mackay, Mercedes Echaide, Grielof Koster, Giancarlo Aquino, Nicola Pelizzi, Jesus Perez-Gil, Fabrizio Salomone, Howard W. Clark, Anthony D. Postle

Source: Journal of Lipid Research, Vol 59, Iss 10, Pp 1880-1892 (2018)

Subject Terms: phosphatidylcholine synthesis, molecular species, stable isotopes, acyl remodeling, mass spectrometry, Biochemistry, QD415-436

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Relation: http://www.sciencedirect.com/science/article/pii/S0022227520341808; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/29b8394737534019b76dd18cc163d901

Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950–Metabolites in Frozen Human Plasma[S]

Authors: John A. Bowden, Alan Heckert, Candice Z. Ulmer, Christina M. Jones, Jeremy P. Koelmel, Laila Abdullah, Linda Ahonen, Yazen Alnouti, Aaron M. Armando, John M. Asara, Takeshi Bamba, John R. Barr, Jonas Bergquist, Christoph H. Borchers, Joost Brandsma, Susanne B. Breitkopf, Tomas Cajka, Amaury Cazenave-Gassiot, Antonio Checa, Michelle A. Cinel, Romain A. Colas, Serge Cremers, Edward A. Dennis, James E. Evans, Alexander Fauland, Oliver Fiehn, Michael S. Gardner, Timothy J. Garrett, Katherine H. Gotlinger, Jun Han, Yingying Huang, Aveline Huipeng Neo, Tuulia Hyötyläinen, Yoshihiro Izumi, Hongfeng Jiang, Houli Jiang, Jiang Jiang, Maureen Kachman, Reiko Kiyonami, Kristaps Klavins, Christian Klose, Harald C. Köfeler, Johan Kolmert, Therese Koal, Grielof Koster, Zsuzsanna Kuklenyik, Irwin J. Kurland, Michael Leadley, Karen Lin, Krishna Rao Maddipati, Danielle McDougall, Peter J. Meikle, Natalie A. Mellett, Cian Monnin, M. Arthur Moseley, Renu Nandakumar, Matej Oresic, Rainey Patterson, David Peake, Jason S. Pierce, Martin Post, Anthony D. Postle, Rebecca Pugh, Yunping Qiu, Oswald Quehenberger, Parsram Ramrup, Jon Rees, Barbara Rembiesa, Denis Reynaud, Mary R. Roth, Susanne Sales, Kai Schuhmann, Michal Laniado Schwartzman, Charles N. Serhan, Andrej Shevchenko, Stephen E. Somerville, Lisa St. John-Williams, Michal A. Surma, Hiroaki Takeda, Rhishikesh Thakare, J. Will Thompson, Federico Torta, Alexander Triebl, Martin Trötzmüller, S. J. Kumari Ubhayasekera, Dajana Vuckovic, Jacquelyn M. Weir, Ruth Welti, Markus R. Wenk, Craig E. Wheelock, Libin Yao, Min Yuan, Xueqing Heather Zhao, Senlin Zhou

Source: Journal of Lipid Research, Vol 58, Iss 12, Pp 2275-2288 (2017)

Subject Terms: fatty acyls, glycerolipids, lipids, phospholipids, quality control, quantitation, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520335549; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/e757670a32e84af9bc9bad52c975b5dc

Increased Alveolar Heparan Sulphate and Reduced Pulmonary Surfactant Amount and Function in the Mucopolysaccharidosis IIIA Mouse

Authors: Tamara L. Paget, Emma J. Parkinson-Lawrence, Paul J. Trim, Chiara Autilio, Madhuriben H. Panchal, Grielof Koster, Mercedes Echaide, Marten F. Snel, Anthony D. Postle, Janna L. Morrison, Jésus Pérez-Gil, Sandra Orgeig

Source: Cells, Vol 10, Iss 4, p 849 (2021)

Subject Terms: MPS IIIA, Sanfilippo syndrome, pulmonary surfactant, respiratory dysfunction, heparan sulphate, bronchoalveolar lavage, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/4/849; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/303771f4fc134b0c98d59b93b6277ab1

Insight into erythrocyte phospholipid molecular flux in healthy humans and in patients with acute respiratory distress syndrome.

Authors: Ahilanandan Dushianthan, Rebecca Cusack, Grielof Koster, Michael P W Grocott, Anthony D Postle

Source: PLoS ONE, Vol 14, Iss 8, p e0221595 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/3deef218d1ef47538a2b4c56c98660f2

Specificity and rate of human and mouse liver and plasma phosphatidylcholine synthesis analyzed in vivo[S]

Authors: Christopher J. Pynn, Neil G. Henderson, Howard Clark, Grielof Koster, Wolfgang Bernhard, Anthony D. Postle

Source: Journal of Lipid Research, Vol 52, Iss 2, Pp 399-407 (2011)

Subject Terms: deuterated choline, lipidomics, multiple isotopomer distribution analysis, phosphatidylethanolamine-N-methyltransferase, stable isotope, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520405371; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/70a76b2cf78d46faa119e0d48bf1c768