Abn-BLIP: Abnormality-aligned Bootstrapping Language-Image Pre-training for Pulmonary Embolism Diagnosis and Report Generation from CTPA

Authors: Zhong, Zhusi, Wang, Yuli, Bi, Lulu, Ma, Zhuoqi, Ahn, Sun Ho, Mullin, Christopher J., Greineder, Colin F., Atalay, Michael K., Collins, Scott, Baird, Grayson L., Lin, Cheng Ting, Stayman, Webster, Kolb, Todd M., Kamel, Ihab, Bai, Harrison X., Jiao, Zhicheng

Subject Terms: Computer Science - Computer Vision and Pattern Recognition, Computer Science - Artificial Intelligence

Access URL: http://arxiv.org/abs/2503.02034

Implementation of an Emergency Department Opioid Use Disorder Initiative: Clinical Processes and Institution Specific Education Improve Care

Authors: Krumheuer, Aaron ^†, Janke, Alexander T ^{†, ‡}, Nickel, Alex ^§, Kim, Erin ^║, Bailes, Carrie ^†, Ager, Emily E. ^†, Purington, Ella K. ^†, Mahmood, Syed Mohammad ^¶, Hooyer, Mitchell ^†, Ryan, Mary Loretta ^#, Baker, Jessica E. ^║, Purdy, Megan ^⁎⁎, Greineder, Colin F. ^†, Commissaris, Carolyn V. ^††, Smith, Shawna N. ^‡‡, Fung, Christopher M. ^†, Losman, Eve D. ^{†, ⁎}

Source: In Journal of Emergency Medicine April 2025 71:104-113

Bispecific antibody shuttles targeting CD98hc mediate efficient and long-lived brain delivery of IgGs

Authors: Pornnoppadol, Ghasidit, Bond, Layne G., Lucas, Michael J., Zupancic, Jennifer M., Kuo, Yun-Huai, Zhang, Boya, Greineder, Colin F., Tessier, Peter M.

Source: In Cell Chemical Biology 15 February 2024 31(2):361-372

Coagulofibrinolytic effects of recombinant soluble thrombomodulin in prolonged porcine cardiac arrest

Authors: Zhang, Boya, McCracken, Brendan M., Mahmood, Carmen Colmenero, Leander, Danielle, Greer, Nicholas, Cranford, James A., Hsu, Cindy H., Tiba, Mohamad Hakam, Neumar, Robert W., Greineder, Colin F.

Source: In Resuscitation Plus December 2023 16

Effect of pulmonary embolism response team on advanced therapies administered: The University of Michigan experience

Authors: Ardeshna, Nelish S., Song, Melinda, Hyder, Syed N., Grace, Kelsey A., O'Hare, Connor, Schaeffer, William J., Stover, Michael, Greineder, Colin F., Barnes, Geoffrey D.

Source: In Thrombosis Research January 2023 221:73-78

Comparative Radiotracing Quantifies Brain Cellular Uptake and Catabolism of Bispecific Antibodies Targeting Transferrin Receptor and CD98hc.

Authors: Veire, Jacob L., Lucas, Michael J., Bond, Layne G., Tripu, Deepika R., Tessier, Peter M., Greineder, Colin F.

Source: ACS Chemical Neuroscience; 4/2/2025, Vol. 16 Issue 7, p1264-1274, 11p

A stepped wedge cluster randomized implementation trial to increase outpatient management of low-risk pulmonary embolism from the emergency department – the MEDIC ALERT PE study.

Authors: Smith, Shawna N., Greineder, Colin F., Errickson, Joshua, Burns, Jessica, Seagull, F Jacob, Kocher, Keith E., Kline, Jeffrey A., Kullgren, Jeffrey T., Lanham, Michael S. M., Krein, Sarah L., Barnes, Geoffrey D.

Source: Implementation Science Communications; 4/2/2025, Vol. 6 Issue 1, p1-13, 13p

Subject Terms: PULMONARY embolism, OUTPATIENTS, RANDOMIZED controlled trials, PATIENT safety, EVIDENCE-based medicine, HOSPITAL emergency services, HEALTH equity

Geographic Terms: UNITED States

Anchoring IgG-degrading enzymes to the surface of platelets selectively neutralizes antiplatelet antibodies

Authors: Lynch, Donald R., Jr, Stringham, Emily N., Zhang, Boya, Balbin-Cuesta, Ginette, Curtis, Brian R., Palumbo, Joseph S., Greineder, Colin F., Tourdot, Benjamin E. ^*

Source: In Blood Advances 9 August 2022 6(15):4645-4656

Optimizing Use of High-Sensitivity Troponin for Risk-Stratification of Acute Pulmonary Embolism.

Authors: Goraya, Sayhaan R., O'Hare, Connor, Grace, Kelsey A., Schaeffer, William J., Hyder, S. Nabeel, Barnes, Geoffrey D., Greineder, Colin F.

Source: Thrombosis & Haemostasis; Dec2024, Vol. 124 Issue 12, p1134-1142, 9p

Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood–brain barrier

Authors: Marcos-Contreras, Oscar A., Greineder, Colin F., Kiseleva, Raisa Yu, Parhiz, Hamideh, Walsh, Landis R., Zuluaga-Ramirez, Viviana, Myerson, Jacob W., Hood, Elizabeth D., Villa, Carlos H., Tombacz, Istvan, Pardi, Norbert, Seliga, Alecia, Mui, Barbara L., Tam, Ying K., Glassman, Patrick M., Shuvaev, Vladimir V., Nong, Jia, Brenner, Jacob S., Khoshnejad, Makan, Madden, Tom, Weissmann, Drew, Persidsky, Yuri, Muzykantov, Vladimir R.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Feb . 117(7), 3405-3414.

Access URL: https://www.jstor.org/stable/26928971

Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain

Authors: Marcos-Contreras, Oscar A., Brenner, Jacob S., Kiseleva, Raisa Y., Zuluaga-Ramirez, Viviana, Greineder, Colin F., Villa, Carlos H., Hood, Elizabeth D., Myerson, Jacob W., Muro, Silvia, Persidsky, Yuri, Muzykantov, Vladimir R.

Source: In Journal of Controlled Release 10 May 2019 301:54-61

JTH in Clinic: management of low-risk pulmonary embolism

Authors: Han, Henry, O’Hare, Connor, Joyce, Elizabeth, Kline, Jeffrey A., Greineder, Colin F., Barnes, Geoffrey D.

Source: In Journal of Thrombosis and Haemostasis December 2024 22(12):3406-3414

Biocompatible coupling of therapeutic fusion proteins to human erythrocytes

Authors: Villa, Carlos H., Pan, Daniel C., Johnston, Ian H., Greineder, Colin F., Walsh, Landis R., Hood, Elizabeth D., Cines, Douglas B., Poncz, Mortimer, Siegel, Don L., Muzykantov, Vladimir R.

Source: In Blood Advances 13 February 2018 2(3):165-176

ICAM-1–targeted thrombomodulin mitigates tissue factor–driven inflammatory thrombosis in a human endothelialized microfluidic model

Authors: Greineder, Colin F. ^*, Johnston, Ian H. ^*, Villa, Carlos H. ^*, Gollomp, Kandace, Esmon, Charles T., Cines, Douglas B., Poncz, Mortimer, Muzykantov, Vladimir R.

Source: In Blood Advances 8 August 2017 1(18):1452-1465

Affinity targeting of therapeutic proteins to the bone surface—local delivery of sclerostin–neutralizing antibody enhances efficacy.

Authors: Zhang, Boya, Swanson, William Benton, Durdan, Margaret, Livingston, Heather N, Dodd, Michaela, Vidanapathirana, Sachith M, Desai, Alec, Douglas, Lindsey, Mishina, Yuji, Weivoda, Megan, Greineder, Colin F

Source: Journal of Bone & Mineral Research; Jun2024, Vol. 39 Issue 6, p717-728, 12p

Mechanisms that determine nanocarrier targeting to healthy versus inflamed lung regions

Authors: Brenner, Jacob S., Bhamidipati, Kartik, Glassman, Patrick M., Ramakrishnan, N., Jiang, Depeng, Paris, Andrew J., Myerson, Jacob W., Pan, Daniel C., Shuvaev, Vladimir V., Villa, Carlos H., Hood, Elizabeth D., Kiseleva, Raisa, Greineder, Colin F., Radhakrishnan, Ravi, Muzykantov, Vladimir R.

Source: In Nanomedicine: Nanotechnology, Biology, and Medicine May 2017 13(4):1495-1506

Molecular engineering of high affinity single-chain antibody fragment for endothelial targeting of proteins and nanocarriers in rodents and humans

Authors: Greineder, Colin F., Hood, Elizabeth D., Yao, Anning, Khoshnejad, Makan, Brenner, Jake S., Johnston, Ian H., Poncz, Mortimer, Gottstein, Claudia, Muzykantov, Vladimir R.

Source: In Journal of Controlled Release 28 March 2016 226:229-237

Endothelial targeting of nanocarriers loaded with antioxidant enzymes for protection against vascular oxidative stress and inflammation

Authors: Hood, Elizabeth D., Chorny, Michael, Greineder, Colin F., S. Alferiev, Ivan, Levy, Robert J., Muzykantov, Vladimir R.

Source: In Biomaterials April 2014 35(11):3708-3715

Endothelial targeting of liposomes encapsulating SOD/catalase mimetic EUK-134 alleviates acute pulmonary inflammation

Authors: Howard, Melissa D., Greineder, Colin F., Hood, Elizabeth D., Muzykantov, Vladimir R.

Source: In Journal of Controlled Release 10 March 2014 177:34-41

Platelet Endothelial Cell Adhesion Molecule Targeted Oxidant-Resistant Mutant Thrombomodulin Fusion Protein with Enhanced Potency In Vitro and In Vivo

Authors: Carnemolla, Ronald, Greineder, Colin F., Chacko, Ann-Marie, Patel, Kruti Rajan, Ding, Bi-Sen, Zaitsev, Sergei, Esmon, Charles T., Muzykantov, Vladimir R. ^*

Source: In The Journal of Pharmacology and Experimental Therapeutics November 2013 347(2):339-345