A prospective phase IIA multicenter double-blinded randomized placebo-controlled clinical trial evaluating the efficacy and safety of inhaled Tobramycin in patients with ventilator-associated pneumonia (iToVAP)

Authors: Angermair, Stefan, Deja, Maria, Thronicke, Anja, Grehn, Claudia, Akbari, Nilufar, Uhrig, Alexander, Asgarpur, Golschan, Spies, Claudia, Treskatsch, Sascha, Schwarz, Carsten

Source: In Anaesthesia Critical Care & Pain Medicine October 2023 42(5)

Risk factors for cystic fibrosis arthropathy: Data from the German cystic fibrosis registry

Authors: Grehn, Claudia, Dittrich, A.-M., Wosniok, J., Holz, F., Hafkemeyer, S., Naehrlich, L., Schwarz, C.

Source: In Journal of Cystic Fibrosis November 2021 20(6):e87-e92

Clinical impact of levofloxacin inhalation solution in cystic fibrosis patients in a real-world setting

Authors: Schwarz, Carsten, Grehn, Claudia, Temming, Svenja, Holz, Frederik, Eschenhagen, Patience Ndidi

Source: In Journal of Cystic Fibrosis November 2021 20(6):1035-1039

Genetic diversification of persistent Mycobacterium abscessus within cystic fibrosis patients

Authors: Lewin, Astrid, Kamal, Elisabeth, Semmler, Torsten, Winter, Katja, Kaiser, Sandra, Schäfer, Hubert, Mao, Lei, Eschenhagen, Patience, Grehn, Claudia, Bender, Jennifer, Schwarz, Carsten

Source: Virulence. 12(1):2415-2429

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138857350.0x000001&indx=1&recIds=ETOCvdc_100138857350.0x000001

Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans

Authors: Bacher, Petra, Hohnstein, Thordis, Beerbaum, Eva, Röcker, Marie, Blango, Matthew G., Kaufmann, Svenja, Röhmel, Jobst, Eschenhagen, Patience, Grehn, Claudia, Seidel, Kathrin, Rickerts, Volker, Lozza, Laura, Stervbo, Ulrik, Nienen, Mikalai, Babel, Nina, Milleck, Julia, Assenmacher, Mario, Cornely, Oliver A., Ziegler, Maren, Wisplinghoff, Hilmar, Heine, Guido, Worm, Margitta, Siegmund, Britta, Maul, Jochen, Creutz, Petra, Tabeling, Christoph, Ruwwe-Glösenkamp, Christoph, Sander, Leif E., Knosalla, Christoph, Brunke, Sascha, Hube, Bernhard, Kniemeyer, Olaf, Brakhage, Axel A., Schwarz, Carsten, Scheffold, Alexander

Source: In Cell 7 March 2019 176(6):1340-1355

Proliferative activity of antigen-specific CD154+ T cells against bacterial and fungal respiratory pathogens in cystic fibrosis decreases after initiation of highly effective CFTR modulator therapy.

Authors: Eschenhagen, Patience N., Bacher, Petra, Grehn, Claudia, Mainz, Jochen G., Scheffold, Alexander, Schwarz, Carsten

Source: Frontiers in Pharmacology; 2023, p1-8, 8p

Subject Terms: MUCOCILIARY system, T cells, CYSTIC fibrosis transmembrane conductance regulator, BACTERIAL cells, CYSTIC fibrosis, B cell receptors

Antibiotic Therapy for Pulmonary Exacerbations in Cystic Fibrosis—A Single-Centre Prospective Observational Study.

Authors: Schwarz, Carsten, Wimmer, Eliana, Holz, Frederik, Grehn, Claudia, Staab, Doris, Eschenhagen, Patience Ndidi

Source: Antibiotics (2079-6382); Apr2023, Vol. 12 Issue 4, p734, 16p

Subject Terms: CYSTIC fibrosis, C-reactive protein, LONGITUDINAL method, SCIENTIFIC observation, DISEASE exacerbation

Genetic diversification of persistent Mycobacterium abscessuswithin cystic fibrosis patients

Authors: Lewin, Astrid, Kamal, Elisabeth, Semmler, Torsten, Winter, Katja, Kaiser, Sandra, Schäfer, Hubert, Mao, Lei, Eschenhagen, Patience, Grehn, Claudia, Bender, Jennifer, Schwarz, Carsten

Source: Virulence; December 2021, Vol. 12 Issue: 1 p2415-2429, 15p

Prospective Evaluation of Aspergillus fumigatus -Specific IgG in Patients With Cystic Fibrosis.

Authors: Eschenhagen, Patience, Grehn, Claudia, Schwarz, Carsten

Source: Frontiers in Cellular & Infection Microbiology; 1/22/2021, Vol. 11, pN.PAG-N.PAG, 8p

Subject Terms: CYSTIC fibrosis, ASPERGILLUS fumigatus, PULMONARY aspergillosis, RECEIVER operating characteristic curves, LUNG diseases, BURKHOLDERIA infections, DIAGNOSIS

Geographic Terms: AFRICA

Frequent Pet Contact as Risk Factor for Allergic Bronchopulmonary Aspergillosis in Cystic Fibrosis.

Authors: Grehn, Claudia, Eschenhagen, Patience, Temming, Svenja, Düesberg, Uta, Neumann, Konrad, Schwarz, Carsten

Source: Frontiers in Cellular & Infection Microbiology; 1/11/2021, Vol. 11, pN.PAG-N.PAG, 6p

Subject Terms: CYSTIC fibrosis, BURKHOLDERIA infections, PET care, ASPERGILLUS fumigatus, MYCOSES, PETS, CHI-squared test, PULMONARY aspergillosis

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Antigen specificity and cross-reactivity drive functionally diverse anti-Aspergillus fumigatus T cell responses in cystic fibrosis.

Authors: Schwarz, Carsten, Eschenhagen, Patience, Schmidt, Henrijette, Hohnstein, Thordis, Iwert, Christina, Grehn, Claudia, Roehme, Jobst, Steinke, Eva, Stahl, Mirjam, Lozza, Laura, Tikhonova, Ekaterina, Rosati, Elisa, Stervbo, Ulrik, Babel, Nina, Mainz, Jochen G., Wisplinghoff, Hilmar, Ebe, Frank, Lei-Jie Jia, Blango, Matthew G., Hortschansky, Peter

Source: Journal of Clinical Investigation. Mar2023, Vol. 133 Issue 5, p1-16. 16p.

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