Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS.

Authors: Md Amin Hossain, Richa Sarin, Daniel P Donnelly, Brandon C Miller, Alexandra Weiss, Luke McAlary, Svetlana V Antonyuk, Joseph P Salisbury, Jakal Amin, Jeremy B Conway, Samantha S Watson, Jenifer N Winters, Yu Xu, Novera Alam, Rutali R Brahme, Haneyeh Shahbazian, Durgalakshmi Sivasankar, Swathi Padmakumar, Aziza Sattarova, Aparna C Ponmudiyan, Tanvi Gawde, David E Verrill, Wensheng Yang, Sunanda Kannapadi, Leigh D Plant, Jared R Auclair, Lee Makowski, Gregory A Petsko, Dagmar Ringe, Nathalie Y R Agar, David J Greenblatt, Mary Jo Ondrechen, Yunqiu Chen, Justin J Yerbury, Roman Manetsch, S Samar Hasnain, Robert H Brown, Jeffrey N Agar

Source: PLoS Biology, Vol 22, Iss 1, p e3002462 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002462&type=printable; https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/ae0b075acaa84b09a950667731983ac1

Brain-wide analysis of the supraspinal connectome reveals anatomical correlates to functional recovery after spinal injury

Authors: Zimei Wang, Adam Romanski, Vatsal Mehra, Yunfang Wang, Matthew Brannigan, Benjamin C Campbell, Gregory A Petsko, Pantelis Tsoulfas, Murray G Blackmore

Source: eLife, Vol 11 (2022)

Subject Terms: supraspinal neurons, spinal cord injury, adeno-associated virus, digital neuroanatomical atlas, tissue clearing, 3D visualization, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/76254; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/f90ed64bf5c34afca4d1275419781379

Targeted stabilization of Munc18‐1 function via pharmacological chaperones

Authors: Debra Abramov, Noah Guy Lewis Guiberson, Andrew Daab, Yoonmi Na, Gregory A Petsko, Manu Sharma, Jacqueline Burré

Source: EMBO Molecular Medicine, Vol 13, Iss 1, Pp 1-18 (2020)

Subject Terms: Munc18‐1, pharmacological chaperone, Rescue, small molecule, STXBP1, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/e20e7216fd4d484a87e0eeb8cc2e6a45

Mycobacterium tuberculosis Hip1 modulates macrophage responses through proteolysis of GroEL2.

Authors: Jacqueline L Naffin-Olivos, Maria Georgieva, Nathan Goldfarb, Ranjna Madan-Lala, Lauren Dong, Erica Bizzell, Ethan Valinetz, Gabriel S Brandt, Sarah Yu, Daniil E Shabashvili, Dagmar Ringe, Ben M Dunn, Gregory A Petsko, Jyothi Rengarajan

Source: PLoS Pathogens, Vol 10, Iss 5, p e1004132 (2014)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4022732?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/ee25a6671c85440f91e045389fbd1621

A yeast model of FUS/TLS-dependent cytotoxicity.

Authors: Shulin Ju, Daniel F Tardiff, Haesun Han, Kanneganti Divya, Quan Zhong, Lynne E Maquat, Daryl A Bosco, Lawrence J Hayward, Robert H Brown, Susan Lindquist, Dagmar Ringe, Gregory A Petsko

Source: PLoS Biology, Vol 9, Iss 4, p e1001052 (2011)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3082520?pdf=render; https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/8b86bc019d774b7c96ffcc6d00dbf142

Testing electrostatic complementarity in enzyme catalysis: hydrogen bonding in the ketosteroid isomerase oxyanion hole.

Authors: Daniel A Kraut, Paul A Sigala, Brandon Pybus, Corey W Liu, Dagmar Ringe, Gregory A Petsko, Daniel Herschlag

Source: PLoS Biology, Vol 4, Iss 4, p e99 (2006)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/98182b1d63cf4d19b5b348af950fb4ae

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RIOK2 transcriptionally regulates TRiC and dyskerin complexes to prevent telomere shortening

Authors: Shrestha Ghosh, Mileena T. Nguyen, Ha Eun Choi, Maximilian Stahl, Annemarie Luise Kühn, Sandra Van der Auwera, Hans J. Grabe, Henry Völzke, Georg Homuth, Samuel A. Myers, Cory M. Hogaboam, Imre Noth, Fernando J. Martinez, Gregory A. Petsko, Laurie H. Glimcher

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/acac83437afc458ea79c24761644c96b

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