NoxO1 regulates EGFR signaling by its interaction with Erbin

Authors: Hebchen, Dana Maureen, Schader, Tim, Spaeth, Manuela, Müller, Niklas, Graumann, Johannes, Schröder, Katrin

Source: In Redox Biology November 2024 77

Secretome Analysis Using Affinity Proteomics and Immunoassays: A Focus on Tumor Biology

Authors: Beutgen, Vanessa M., Shinkevich, Veronika, Pörschke, Johanna, Meena, Celina, Steitz, Anna M., Pogge von Strandmann, Elke, Graumann, Johannes, Gómez-Serrano, María

Source: In Molecular & Cellular Proteomics September 2024 23(9)

Inhibition of autophagy prevents cardiac dysfunction at early stages of cardiomyopathy in Bag3-deficient hearts

Authors: Maroli, Giovanni, Schänzer, Anne, Günther, Stefan, Garcia-Gonzalez, Claudia, Rupp, Stefan, Schlierbach, Hannah, Chen, Yanpu, Graumann, Johannes, Wietelmann, Astrid, Kim, Johnny, Braun, Thomas

Source: In Journal of Molecular and Cellular Cardiology August 2024 193:53-66

TRAIL-dependent apoptosis of peritoneal mesothelial cells by NK cells promotes ovarian cancer invasion

Authors: Steitz, Anna Mary ¹, Schröder, Clarissa ¹, Knuth, Isabel ¹, Keber, Corinna U. ², Sommerfeld, Leah ¹, Finkernagel, Florian ¹, Jansen, Julia M. ³, Wagner, Uwe ³, Müller-Brüsselbach, Sabine ¹, Worzfeld, Thomas ⁴, Huber, Magdalena ⁵, Beutgen, Vanessa M. ^{6, 7}, Graumann, Johannes ^{6, 7}, Pogge von Strandmann, Elke ⁸, Müller, Rolf ^{1, 9, ∗}, Reinartz, Silke ^{1, ∗∗}

Source: In iScience 15 December 2023 26(12)

ADAR1 Prevents Autoinflammatory Processes in the Heart Mediated by IRF7

Authors: Garcia-Gonzalez, Claudia, Dieterich, Christoph, Maroli, Giovanni, Wiesnet, Marion, Wietelmann, Astrid, Li, Xiang, Yuan, Xuejun, Graumann, Johannes, Stellos, Konstantinos, Kubin, Thomas, Schneider, Andre, Braun, Thomas

Source: Circulation research. 131(7):580-597

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172918117.0x000001&indx=1&recIds=ETOCvdc_100172918117.0x000001

Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival

Authors: Kudryashova, Tatiana V., Dabral, Swati, Nayakanti, Sreenath, Ray, Arnab, Goncharov, Dmitry A., Avolio, Theodore, Shen, Yuanjun, Rode, Analise, Pena, Andressa, Jiang, Lifeng, Lin, Derek, Baust, Jeffrey, Bachman, Timothy N., Graumann, Johannes, Ruppert, Clemens, Guenther, Andreas, Schmoranzer, Mario, Grobs, Yann, Eve Lemay, Sarah, Tremblay, Eve, Breuils-Bonnet, Sandra, Boucherat, Olivier, Mora, Ana L., DeLisser, Horace, Zhao, Jing, Zhao, Yutong, Bonnet, Sébastien, Seeger, Werner, Pullamsetti, Soni S., Goncharova, Elena A.

Source: Circulation research. 130(5):760-778

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155075870.0x000001&indx=1&recIds=ETOCvdc_100155075870.0x000001

Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK‐STAT signaling in macrophages by perturbing lipid raft structures

Authors: Hammoud, Mohamad K., Dietze, Raimund, Pesek, Jelena, Finkernagel, Florian, Unger, Annika, Bieringer, Tim, Nist, Andrea, Stiewe, Thorsten, Bhagwat, Aditya M., Nockher, Wolfgang Andreas, Reinartz, Silke, Müller‐Brüsselbach, Sabine, Graumann, Johannes, Müller, Rolf

Source: Molecular oncology. 16(17):3146-3166

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100159582309.0x000001&indx=1&recIds=ETOCvdc_100159582309.0x000001

Basal cell adhesion molecule (BCAM) promotes mesothelial-to-mesenchymal transition and tumor angiogenesis through paracrine signaling.

Authors: Sivakumar, Suresh, Lieber, Sonja, Dietze, Raimund, Beutgen, Vanessa M., Sutor, Eileen C., Heidemann, Sophie, Finkernagel, Florian, Teply-Szymanski, Julia, Nist, Andrea, Stiewe, Thorsten, Roth, Katrin, Reinartz, Silke, Graumann, Johannes, Müller-Brüsselbach, Sabine, Müller, Rolf

Source: Cell Communication & Signaling; 3/13/2025, Vol. 23 Issue 1, p1-21, 21p

SIAH3 is frequently epigenetically silenced in cancer and regulates mitochondrial metabolism.

Authors: Deutschmeyer, Verena E., Schlaudraff, Nico A., Walesch, Sara K., Moyer, Janine, Sokol, Anna M., Graumann, Johannes, Meissner, Wolfgang, Schneider, Marc, Muley, Thomas, Helmbold, Peter, Schwinn, Markus, Richter, Antje M., Schmitz, M. Lienhard, Dammann, Reinhard H.

Source: International Journal of Cancer; Jan2025, Vol. 156 Issue 2, p353-367, 15p

Subject Terms: ORGANELLE formation, UBIQUITIN ligases, HEAD & neck cancer, CELL metabolism, OXIDATIVE phosphorylation

The E3 ubiquitin-protein ligase Rbx1 regulates cardiac wall morphogenesis in zebrafish

Authors: Sarvari, Pourya, Rasouli, S. Javad, Allanki, Srinivas, Stone, Oliver A., Sokol, Anna M., Graumann, Johannes, Stainier, Didier Y.R.

Source: In Developmental Biology December 2021 480:1-12

Directed Evolution of an Enhanced POU Reprogramming Factor for Cell Fate Engineering

Authors: Tan, Daisylyn Senna, Chen, Yanpu, Gao, Ya, Bednarz, Anastasia, Wei, Yuanjie, Malik, Vikas, Ho, Derek Hoi-Hang, Weng, Mingxi, Ho, Sik Yin, Srivastava, Yogesh, Velychko, Sergiy, Yang, Xiaoxiao, Fan, Ligang, Kim, Johnny, Graumann, Johannes, Stormo, Gary D., Braun, Thomas, Yan, Jian, Schöler, Hans R., Jauch, Ralf

Source: Molecular biology and evolution. 38(7):2854-2868

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132297632.0x000001&indx=1&recIds=ETOCvdc_100132297632.0x000001

Arachidonic acid impairs natural killer cell functions by disrupting signaling pathways driven by activating receptors and reactive oxygen species.

Authors: Hammoud, Mohamad K., Meena, Celina, Dietze, Raimund, Hoffmann, Nathalie, Szymanski, Witold, Finkernagel, Florian, Nist, Andrea, Stiewe, Thorsten, Graumann, Johannes, von Strandmann, Elke Pogge, Müller, Rolf

Source: Cell Communication & Signaling; 11/19/2024, Vol. 22 Issue 1, p1-23, 23p

Subject Terms: KILLER cells, UNSATURATED fatty acids, BIOLOGICAL assay, ARACHIDONIC acid, CELL receptors

DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer.

Authors: Brichkina, Anna, Ems, Miriam, Suezov, Roman, Singh, Rajeev, Lutz, Veronika, Picard, Felix S. R., Nist, Andrea, Stiewe, Thorsten, Graumann, Johannes, Daude, Michael, Diederich, Wibke E., Finkernagel, Florian, Ho-Ryun Chung, Bartsch, Detlef K., Roth, Katrin, Keber, Corinna, Denkert, Carsten, Huber, Magdalena, Gress, Thomas M., Lauth, Matthias

Source: Gut; Oct2024, Vol. 73 Issue 10, p1684-1701, 18p

Subject Terms: MOLECULAR biology, TRANSFORMING growth factors-beta, CANCER cell physiology, LIFE sciences, CELL receptors, PANCREATIC intraepithelial neoplasia, PANCREATIC tumors

Basal cell adhesion molecule promotes metastasis‐associated processes in ovarian cancer

Authors: Sivakumar, Suresh, Lieber, Sonja, Librizzi, Damiano, Keber, Corinna, Sommerfeld, Leah, Finkernagel, Florian, Roth, Katrin, Reinartz, Silke, Bartsch, Jörg W., Graumann, Johannes, Müller‐Brüsselbach, Sabine, Müller, Rolf

Source: Clinical and translational medicine. 13(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172693637.0x000001&indx=1&recIds=ETOCvdc_100172693637.0x000001

Remodeling of ER–plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca 2+ influx in mitosis

Authors: Yu, Fang, Hubrack, Satanay Z., Chakraborty, Sumita, Sun, Lu, Alcantara-Adap, Ethel, Kulkarni, Rashmi, Billing, Anja M., Graumann, Johannes, Taylor, Colin W., Machaca, Khaled

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 May . 116(21), 10392-10401.

Access URL: https://www.jstor.org/stable/26706264

Mechanical Forces Regulate Cardiomyocyte Myofilament Maturation via the VCL-SSH1-CFL Axis

Authors: Fukuda, Ryuichi, Gunawan, Felix, Ramadass, Radhan, Beisaw, Arica, Konzer, Anne, Mullapudi, Sri Teja, Gentile, Alessandra, Maischein, Hans-Martin, Graumann, Johannes, Stainier, Didier Y.R.

Source: In Developmental Cell 7 October 2019 51(1):62-77

A Systems-level Characterization of the Differentiation of Human Embryonic Stem Cells into Mesenchymal Stem Cells*[S]

Authors: Billing, Anja M. ^{‡, ‖‖, §§}, Dib, Shaima S. ^‡, Bhagwat, Aditya M. ^‡, da Silva, Israel T. ^{§, ¶}, Drummond, Rodrigo D. ^§, Hayat, Shahina ^‡, Al-Mismar, Rasha ^‡, Ben-Hamidane, Hisham ^‡, Goswami, Neha ^‡, Engholm-Keller, Kasper ^{‖, **}, Larsen, Martin R. ^‖, Suhre, Karsten ^‡, Rafii, Arash ^{‡, ‡‡}, Graumann, Johannes ^{‡, ¶¶, ‡‡‡}

Source: In Molecular & Cellular Proteomics October 2019 18(10):1950-1966

MARMoSET – Extracting Publication-ready Mass Spectrometry Metadata from RAW Files

Authors: Kiweler, Marina ^‡, Looso, Mario ^{‡, ¶, ‡‡}, Graumann, Johannes ^{§, ¶, ‖}

Source: In Molecular & Cellular Proteomics August 2019 18(8):1700-1702

An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study- Identified Diabetes Genes and Drug Discovery

Authors: Zeng, Hui, Guo, Min, Zhou, Ting, Tan, Lei, Chong, Chi Nok, Zhang, Tuo, Dong, Xue, Xiang, Jenny Zhaoying, Yu, Albert S., Yue, Lixia, Qi, Qibin, Evans, Todd, Graumann, Johannes, Chen, Shuibing

Source: Cell Stem Cell; October 2024, Vol. 31 Issue: 10 p1543-1547, 5p

A PhotoClick cholesterol‐based quantitative proteomics screen for cytoplasmic sterol‐binding proteins in Saccharomyces cerevisiae

Authors: Chauhan, Neha, Sere, Yves Y., Sokol, Anna M., Graumann, Johannes, Menon, Anant K.

Source: Yeast. 37(1):15-25

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100143464851.0x000001&indx=1&recIds=ETOCvdc_100143464851.0x000001