Quantification of cinpanemab (BIIB054) binding to α-synuclein in cerebrospinal fluid of phase 1 single ascending dose samples

Authors: Liu, YuTing ^∗, Yang, Minhua, Fraser, Kyle, Graham, Danielle, Weinreb, Paul H., Weihofen, Andreas, Hirst, Warren D., Cedarbaum, Jesse M., Pepinsky, Blake

Source: In The Journal of Pharmacology and Experimental Therapeutics January 2025 392(1)

Development of a horizontal transmission model to assess the effects of exposure to pathogenic E. cecorum during the hatching phase in broiler chickens

Authors: Higuita, James ^a, Arango, Marcela ^a, Forga, Aaron ^a, Rowland, Mitch ^a, Liu, Jundi ^b, Wolfenden, Ross ^b, Graham, Danielle ^{a, ⁎}

Source: In Poultry Science January 2025 104(1)

Successful Use of a Cadaver Model to Teach Ultrasound-Guided Breast Procedures to Surgical Trainees

Authors: Huy, Tess C., Thompson, Carlie K., Deranteriassian, Aletta, Peacock, Warwick, Tillou, Areti, Baker, Jennifer L., Graham, Danielle S., Chang, Grace, Kapoor, Nimmi S.

Source: In Journal of Surgical Research October 2024 302:274-280

Safety, tolerability, and pharmacokinetics of antisense oligonucleotide BIIB078 in adults with C9orf72-associated amyotrophic lateral sclerosis: a phase 1, randomised, double blinded, placebo-controlled, multiple ascending dose study

Authors: van den Berg, Leonard H ^*, Rothstein, Jeffrey D, Shaw, Pamela J, Babu, Suma, Benatar, Michael, Bucelli, Robert C, Genge, Angela, Glass, Jonathan D, Hardiman, Orla, Libri, Vincenzo, Mobach, Theodore, Oskarsson, Björn, Pattee, Gary L, Ravits, John, Shaw, Christopher E, Weber, Markus, Zinman, Lorne, Jafar-nejad, Paymaan, Rigo, Frank, Lin, Luan, Ferguson, Toby A, Gotter, Anthony L, Graham, Danielle, Monine, Michael, Inra, Jennifer, Sinks, Susie, Eraly, Satish, Garafalo, Steve, Fradette, Stephanie

Source: In The Lancet Neurology September 2024 23(9):901-912

Safety and margin positivity rates of surgeon-performed intraoperative ultrasound-guided wire localization for breast cancer

Authors: Huy, Tess, Graham, Danielle S., Baker, Jennifer L., Thompson, Carlie K., Smith, Courtney, Holt, Anouchka Coste, Kapoor, Nimmi S.

Source: In Surgical Oncology Insight June 2024 1(2)

Does 'Low-Grade' Dedifferentiated Liposarcoma Exist? The Role of Mitotic Index in Separating Dedifferentiated Liposarcoma From Cellular Well-differentiated Liposarcoma

Authors: Graham, Danielle S., Qorbani, Amir, Eckardt, Mark A., Klingbeil, Kyle D., Chen, Lucia Y., Chopra, Shefali, Eilber, Fritz C., Dry, Sarah M.

Source: American journal of surgical pathology. 47(6):649-660

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191123964.0x000001&indx=1&recIds=ETOCvdc_100191123964.0x000001

Independent study demonstrates amyloid probability score accurately indicates amyloid pathology

Authors: Fogelman, Ilana, West, Tim, Braunstein, Joel B., Verghese, Philip B., Kirmess, Kristopher M., Meyer, Matthew R., Contois, John H., Shobin, Eli, Ferber, Kyle L., Gagnon, Jake, Rubel, Carrie E., Graham, Danielle, Bateman, Randall J., Holtzman, David M., Huang, Shuguang, Yu, Joanne, Yang, Sha, Yarasheski, Kevin E.

Source: Annals of clinical and translational neurology. 10(5):765-778

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182608783.0x000001&indx=1&recIds=ETOCvdc_100182608783.0x000001

LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's Disease

Authors: Jennings, Danna, Huntwork‐Rodriguez, Sarah, Vissers, Maurits F.J.M., Daryani, Vinay M., Diaz, Dolores, Goo, Marisa S., Chen, John J., Maciuca, Romeo, Fraser, Kyle, Mabrouk, Omar S., Wetering de Rooij, Jeroen, Heuberger, Jules A.A.C., Groeneveld, Geert Jan, Borin, Marie T., Cruz‐Herranz, Andrés, Graham, Danielle, Scearce‐Levie, Kimberly, De Vicente, Javier, Henry, Anastasia G., Chin, Peter, Ho, Carole, Troyer, Matthew D.

Source: Movement disorders. 38(3):386-398

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182083528.0x000001&indx=1&recIds=ETOCvdc_100182083528.0x000001

Information-Rich, Dual-Function ^1^3C/^2H-Isotopic Crosstalk NMR Assay for Human Serine Racemase (hSR) Provides a PLP-Enzyme 'Partitioning Fingerprint' and Reveals Disparate Chemotypes for hSR Inhibition

Authors: de Dios, Stephany M. Ramos, Hass, Jared L., Graham, Danielle L., Kumar, Nivesh, Antony, Aina E., Morton, Martha D., Berkowitz, David B.

Source: Journal of the American Chemical Society. 145(5):3158-3174

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631672885&indx=1&recIds=ETOCRN631672885

A pediatric quantitative systems pharmacology model of neurofilament trafficking in spinal muscular atrophy treated with the antisense oligonucleotide nusinersen

Authors: Paris, Alessio, Bora, Pranami, Parolo, Silvia, MacCannell, Drew, Monine, Michael, Munnik, Nick, Tong, Xiao, Eraly, Satish, Berger, Zdenek, Graham, Danielle, Ferguson, Toby, Domenici, Enrico, Nestorov, Ivan, Marchetti, Luca

Source: CPT: pharmacometrics & systems pharmacology. 12(2):196-206

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175280586.0x000001&indx=1&recIds=ETOCvdc_100175280586.0x000001

Characterizing the impact of Enterococcus cecorum infection during late embryogenesis on disease progression, cecal microbiome composition, and early performance in broiler chickens

Authors: Arango, Marcela ^*, Forga, Aaron ^*, Liu, Jing, Zhang, Guolong, Gray, Latasha ^*, Moore, Randy, Coles, Makenly ^*, Atencio, Abdiel ^*, Trujillo, Carolina ^*, Latorre, Juan David ^*, Tellez-Isaias, Guillermo ^*, Hargis, Billy ^*, Graham, Danielle ^*

Source: In Poultry Science November 2023 102(11)

Evaluation of Clostridium septicum hemolytic activity, administration route, and dosage volume of a clostridial dermatitis (cellulitis) bacterin-toxoid on humoral immune response in commercial turkeys

Authors: Forga, Aaron ^*, Robbins, Kabel, Smith, Andrew, Coles, Makenly ^*, Tellez-Isaias, Guillermo ^*, Vuong, Christine N. ^*, Hargis, Billy ^*, Graham, Danielle ^*

Source: In Poultry Science September 2023 102(9)

Research Note: Isolation, speciation, and anticoccidial sensitivity of Eimeria spp. recovered from wild turkey feces in the United States

Authors: Trujillo-Peralta, Carolina ^*, Ashcraft, Aaron ^*, Señas-Cuesta, Roberto ^*, Coles, Makenly ^*, Hernandez-Velasco, Xochitl, Selby, Callie ^*, Forga, Aaron ^*, Tellez-Isaias, Guillermo ^*, Vuong, Christine ^*, Bielke, Lisa, Barta, John, Hargis, Billy ^*, Graham, Danielle ^*

Source: In Poultry Science August 2023 102(8)

An age‐dependent mathematical model of neurofilament trafficking in healthy conditions

Authors: Paris, Alessio, Bora, Pranami, Parolo, Silvia, Monine, Michael, Tong, Xiao, Eraly, Satish, Masson, Eric, Ferguson, Toby, McCampbell, Alexander, Graham, Danielle, Domenici, Enrico, Nestorov, Ivan, Marchetti, Luca

Source: CPT: pharmacometrics & systems pharmacology. 11(4):447-457

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100147557475.0x000001&indx=1&recIds=ETOCvdc_100147557475.0x000001

Design of a Randomized, Placebo-Controlled, Phase 3 Trial of Tofersen Initiated in Clinically Presymptomatic SOD1 Variant Carriers: the ATLAS Study

Authors: Benatar, Michael, Wuu, Joanne, Andersen, Peter M., Bucelli, Robert C., Andrews, Jinsy A., Otto, Markus, Farahany, Nita A., Harrington, Elizabeth A., Chen, Weiping, Mitchell, Adele A., Ferguson, Toby, Chew, Sheena, Gedney, Liz, Oakley, Sue, Heo, Jeong, Chary, Sowmya, Fanning, Laura, Graham, Danielle, Sun, Peng, Liu, Yingying, Wong, Janice, Fradette, Stephanie

Source: In Neurotherapeutics July 2022 19(4):1248-1258

2024 White paper on recent issues in bioanalysis: Impact of LDT in US and IVDR in EU; AI/ML for High Parameter Flow Cytometry; The rise of Olink Technology; CDx for AAV Gene Therapies; Integrative Bioanalysis by Multiple Platforms; Super Sensitive ADA/NAb LBA (PART 2A – Recommendations on Advanced Strategies for Biomarkers, IVD/CDx Assays (BAV), Cell Based Assays (CBA), and Ligand-Binding Assays (LBA) PART 2B – Regulatory Agencies' Input on Biomarkers, IVD/CDx, and Biomarker Assay Validation)

Authors: Bivi, Nicoletta, Graham, Danielle, Joglekar, Laura, McGuire, Kristina, Stoop, Jeroen, Zoghbi, Jad, Baker, Brian, Bandukwala, Abbas, Bond, Sarah, Buoninfante, Alessandra, Chen, Jeff, Dysinger, Mark, Engelbergs, Jörg, Fiscella, Michele, Garofolo, Fabio, Hopper, Shirley, Jones, Barry, King, Lindsay, Murphy, Rocio, Palmer, Rachel

Source: Bioanalysis; Feb2025, Vol. 17 Issue 4, p211-248, 38p

Assessing the effects of a mixed Eimeria spp. challenge on performance, intestinal integrity, and the gut microbiome of broiler chickens.

Authors: Graham, Danielle, Petrone-Garcia, Victor M., Hernandez-Velasco, Xochitl, Coles, Makenly E., Juarez-Estrada, Marco A., Latorre, Juan D., Chai, Jianmin, Shouse, Stephanie, Zhao, Jiangchao, Forga, Aaron J., Senas-Cuesta, Roberto, Laverty, Lauren, Martin, Kristen, Trujillo-Peralta, Carolina, Loeza, Ileana, Gray, Latasha S., Hargis, Billy M., Tellez-Isaias, Guillermo

Source: Frontiers in Veterinary Science; 2025, p1-11, 11p

Subject Terms: INTESTINAL barrier function, BROILER chickens, EIMERIA tenella, GUT microbiome, TIGHT junctions

Evaluation of an SCCT-Based Intervention to Increase Postsecondary Awareness in Rural Appalachian Youth

Authors: Gibbons, Melinda M., Hardin, Erin E. (ORCID 0000-0003-4058-1068), Taylor, Anna Lora, Brown, Emily, Graham, Danielle

Source: Journal of Career Development. Aug 2020 47(4):424-439.

Peer Reviewed: Y

Page Count: 16

Sponsoring Agency: National Institutes of Health (DHHS)

Descriptors: Social Cognition, Career Education, Rural Areas, Rural Youth, Career Readiness, College Readiness, High School Students, Student Attitudes, Program Evaluation, College Planning, Career Planning, Intervention, STEM Education, Medical Education, Medicine

Geographic Terms: Tennessee

Conceptualizing college‐going volition in rural Appalachian high school students.

Authors: Graham, Danielle L.^1,2 (AUTHOR), Hardin, Erin E.¹ (AUTHOR) erin.hardin@utk.edu, Gibbons, Melinda M.³ (AUTHOR)

Source: Career Development Quarterly. Dec2023, Vol. 71 Issue 4, p252-266. 15p.

Subject Terms: *HIGH school students, *FIRST-generation college students, *PSYCHOMETRICS, *CONTROL (Psychology), *POSTSECONDARY education, *RURAL schools

Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study

Authors: Thijssen, Elisabeth H ^*, La Joie, Renaud ^*, Strom, Amelia, Fonseca, Corrina, Iaccarino, Leonardo, Wolf, Amy, Spina, Salvatore, Allen, Isabel E, Cobigo, Yann, Heuer, Hilary, VandeVrede, Lawren, Proctor, Nicholas K, Lago, Argentina Lario, Baker, Suzanne, Sivasankaran, Rajeev, Kieloch, Agnieszka, Kinhikar, Arvind, Yu, Lili, Valentin, Marie-Anne, Jeromin, Andreas, Zetterberg, Henrik, Hansson, Oskar, Mattsson-Carlgren, Niklas, Graham, Danielle, Blennow, Kaj, Kramer, Joel H, Grinberg, Lea T, Seeley, William W, Rosen, Howard, Boeve, Bradley F, Miller, Bruce L, Teunissen, Charlotte E, Rabinovici, Gil D, Rojas, Julio C, Dage, Jeffrey L, Boxer, Adam L ^*

Source: In The Lancet Neurology September 2021 20(9):739-752