Quorum sensing molecules as a novel microbial factor impacting muscle cells

Authors: De Spiegeleer, Anton, Elewaut, Dirk, Van Den Noortgate, Nele, Janssens, Yorick, Debunne, Nathan, Van Langenhove, Selien, Govindarajan, Srinath, De Spiegeleer, Bart, Wynendaele, Evelien

Source: In BBA - Molecular Basis of Disease 1 March 2020 1866(3)

Lipidomic scanning of self-lipids identifies headless antigens for natural killer T cells.

Authors: Tan-Yun Cheng, Praveena, T., Govindarajan, Srinath, Almeida, Catarina F., Pellicci, Daniel G., Arkins, Wellington C., Van Rhijn, Ildiko, Venken, Koen, Elewaut, Dirk, Godfrey, Dale I., Rossjohn, Jamie, Moody, D. Branch

Source: Proceedings of the National Academy of Sciences of the United States of America; 8/20/2024, Vol. 121 Issue 34, p1-10, 26p

Subject Terms: CYTOTOXIC T cells, KILLER cells, T cell receptors, CERAMIDES, AUTOANTIGENS

Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1

Authors: Bloch, Yehudi, Bouchareychas, Laura, Merceron, Romain, Składanowska, Katarzyna, Van den Bossche, Lien, Detry, Sammy, Govindarajan, Srinath, Elewaut, Dirk, Haerynck, Filomeen, Dullaers, Melissa, Adamopoulos, Iannis E., Savvides, Savvas N.

Source: In Immunity 16 January 2018 48(1):45-58

Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha

Authors: Govindarajan, Srinath, Gaublomme, Djoere, Van der Cruyssen, Renée, Verheugen, Eveline, Van Gassen, Sofie, Saeys, Yvan, Tavernier, Simon, Iwawaki, Takao, Bloch, Yehudi, Savvides, Savvas., Lambrecht, Bart, Janssens, Sophie, Elewaut, Dirk, Drennan, Michael

Source: Nature communications. 9(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099937688.0x000001&indx=1&recIds=ETOCvdc_100099937688.0x000001

The calcium dynamics of human dental pulp stem cells stimulated with tricalcium silicate-based cements determine their differentiation and mineralization outcome

Authors: Rathinam, Elanagai, Govindarajan, Srinath, Rajasekharan, Sivaprakash, Declercq, Heidi, Elewaut, Dirk, De Coster, Peter, Martens, Luc, Leybaert, Luc

Source: Scientific reports. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194144821.0x000001&indx=1&recIds=ETOCvdc_100194144821.0x000001

Design of cholesterol arabinogalactan anchored liposomes for asialoglycoprotein receptor mediated targeting to hepatocellular carcinoma: In silico modeling, in vitro and in vivo evaluation

Authors: Pathak, Pankaj, Dhawan, Vivek, Magarkar, Aniket, Danne, Reinis, Govindarajan, Srinath, Ghosh, Sandipto, Steiniger, Frank, Chaudhari, Pradip, Gopal, Vijaya, Bunker, Alex, Róg, Tomasz, Fahr, Alfred, Nagarsenker, Mangal

Source: International journal of pharmaceutics. 509(1/2):149-158

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100058788934.0x000001&indx=1&recIds=ETOCvdc_100058788934.0x000001

NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20

Authors: Drennan, Michael B., Govindarajan, Srinath, Verheugen, Eveline, Coquet, Jonathan M., Staal, Jens, McGuire, Conor, Taghon, Tom, Leclercq, Georges, Beyaert, Rudi, van Loo, Geert

Source: Journal of experimental medicine. 213(10):1973-1982

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN608056772&indx=1&recIds=ETOCRN608056772

ER stress in antigen‐presenting cells promotes NKT cell activation through endogenous neutral lipids

Authors: Govindarajan, Srinath, Verheugen, Eveline, Venken, Koen, Gaublomme, Djoere, Maelegheer, Margaux, Cloots, Eva, Gysens, Fien, De Geest, Bruno G, Cheng, Tan‐Yun, Moody, D Branch, Janssens, Sophie, Drennan, Michael, Elewaut, Dirk

Source: EMBO reports. 21(6)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140048986.0x000001&indx=1&recIds=ETOCvdc_100140048986.0x000001

Targeting human epidermal growth factor receptor 2 by a cell-penetrating peptide–affibody bioconjugate

Authors: Govindarajan, Srinath, Sivakumar, Jeyarajan, Garimidi, Prathyusha, Rangaraj, Nandini, Kumar, Jerald M., Rao, Nalam M., Gopal, Vijaya

Source: In Biomaterials 2012 33(8):2570-2582

Bacterial Quorum-Sensing Peptides as Immune Modulators Present in Systemic Circulation.

Authors: De Spiegeleer, Anton, Descamps, Amélie, Govindarajan, Srinath, Coudenys, Julie, Van der borght, Kevin, Hirmz, Hannah, Van Den Noortgate, Nele, Elewaut, Dirk, De Spiegeleer, Bart, Wynendaele, Evelien

Source: Biomolecules (2218-273X); Feb2023, Vol. 13 Issue 2, p296, 14p

Subject Terms: IMMUNOMODULATORS, PEPTIDES, LIQUID chromatography-mass spectrometry, IMMUNE system

WITHDRAWN: This article has been withdrawn

Authors: De Spiegeleer, Anton, Elewaut, Dirk, Van Den Noortgate, Nele, Janssens, Yorick, Debunne, Nathan, Van Langenhove, Selien, Govindarajan, Srinath, De Spiegeleer, Bart, Wynendaele, Evelien

Source: In BBA - Molecular Basis of Disease September 2019

Transcriptomic profiling of human dental pulp cells treated with tricalcium silicate–based cements by RNA sequencing.

Authors: Rathinam, Elanagai¹ (AUTHOR) Elanagai.rathinam@ugent.be, Govindarajan, Srinath^2,3 (AUTHOR), Rajasekharan, Sivaprakash¹ (AUTHOR), Declercq, Heidi^4,5 (AUTHOR), Elewaut, Dirk^2,3 (AUTHOR), De Coster, Peter⁶ (AUTHOR), Martens, Luc¹ (AUTHOR)

Source: Clinical Oral Investigations. May2021, Vol. 25 Issue 5, p3181-3195. 15p. 2 Diagrams, 3 Charts, 4 Graphs.

Subject Terms: *RNA sequencing, *DENTAL pulp, *SILICATE cements (Dentistry), *GENE expression, *DENTITION, *CEMENT

Geographic Terms: TULSA (Okla.)

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The Crosstalk Between Leptin Receptor Activation and iNKT Mediated Anti-Tumor Immunity in Multiple Myeloma

Authors: Favreau, Mérédis ^*, Menu, Eline ^*, Vanderkerken, Karin, Faict, Sylvia ^*, Maes, Ken ^*, Van Valckenborgh, Els ^*, De Bruyne, Elke ^*, Govindarajan, Srinath ^*, Drennan, Michael ^*, Leleu, Xavier, Zabeau, Lennart ^*, Tavernier, Jan ^*, Venken, Koen ^*, Elewaut, Dirk ^*

Source: In Blood 2 December 2016 128(22):2075-2075

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