SEMPAI: a Self-Enhancing Multi-Photon Artificial Intelligence for prior-informed assessment of muscle function and pathology

Authors: Mühlberg, Alexander, Ritter, Paul, Langer, Simon, Goossens, Chloë, Nübler, Stefanie, Schneidereit, Dominik, Taubmann, Oliver, Denzinger, Felix, Nörenberg, Dominik, Haug, Michael, Goldmann, Wolfgang H., Maier, Andreas K., Friedrich, Oliver, Kreiss, Lucas

Subject Terms: Computer Science - Computer Vision and Pattern Recognition, Computer Science - Machine Learning, Quantitative Biology - Quantitative Methods, I.2.6, I.4, I.5, J.3

Access URL: http://arxiv.org/abs/2210.16273

Characteristics and prognosis of patients with primary metastatic disease vs. recurrent HER2-negative, hormone receptor-positive advanced breast cancer

Authors: Walter, Christina B. ^a, Hartkopf, Andreas D. ^a, Hein, Alexander ^b, Fasching, Peter A. ^{b, ⁎}, Kolberg, Hans-Christian ^c, Hadji, Peyman ^d, Tesch, Hans ^e, Häberle, Lothar ^{b, f}, Ettl, Johannes ^{g, h}, Lüftner, Diana ⁱ, Wallwiener, Markus ^j, Müller, Volkmar ^k, Beckmann, Matthias W. ^{b, l}, Michel, Laura L. ^m, Belleville, Erik ⁿ, Huebner, Hanna ^b, Uhrig, Sabrina ^b, Goossens, Chloë ^b, Wimberger, Pauline ^{o, p, q, r, s, t}, Hielscher, Carsten ^u, Meyer, Julia ^{b, f}, Mundhenke, Christoph ^v, Kurbacher, Christian ^w, Wuerstlein, Rachel ^x, Untch, Michael ^y, Janni, Wolfgang ^z, Taran, Florin-Andrei ^aa, Lux, Michael P. ^{ab, ac}, Wallwiener, Diethelm ^a, Brucker, Sara Y. ^a, Schneeweiss, Andreas ^m, Fehm, Tanja N. ^{ad, ae}, Fremd, Carlo ^{af, ag, ah}

Source: In The Breast April 2025 80

Prognostic impact of selection criteria of current adjuvant endocrine therapy trials NATALEE and monarchE in postmenopausal HRpos/HER2neg breast cancer patients treated with upfront letrozole

Authors: Fasching, Peter A., Hack, Carolin C., Nabieva, Naiba, Maass, Nicolai, Aktas, Bahriye, Kümmel, Sherko, Thomssen, Christoph, Wolf, Christopher, Kolberg, Hans-Christian, Brucker, Cosima, Janni, Wolfgang, Dall, Peter, Schneeweiss, Andreas, Marme, Frederik, Sütterlin, Marc W., Ruebner, Matthias, Theuser, Anna-Katharin, Kellner, Sara, Hofmann, Nadine M., Böhm, Sybille, Almstedt, Katrin, Lück, Hans-Joachim, Schmatloch, Sabine, Kalder, Matthias, Uleer, Christoph, Jurhasz-Böss, Ingolf, Hanf, Volker, Jackisch, Christian, Müller, Volkmar, Rack, Brigitte, Belleville, Erik, Wallwiener, Diethelm, Rody, Achim, Rauh, Claudia, Bayer, Christian M., Uhrig, Sabrina, Goossens, Chloë, Huebner, Hanna, Brucker, Sara Y., Hein, Alexander, Fehm, Tanja N., Häberle, Lothar

Source: In European Journal of Cancer September 2024 209

Effect of delayed isolation of peripheral blood mononuclear cells on cell viability and functionality.

Authors: Lehle, Sarah, Völkl, Simon, Seitz, Katharina, Goossens, Chloë, Emons, Julius, Ruebner, Matthias, Uhrig, Sabrina, Ziegler, Philipp, Theuser, Anna-Katharin, Beckmann, Matthias W., Fasching, Peter A., Huebner, Hanna

Source: BMC Immunology; 3/15/2025, Vol. 26 Issue 1, p1-13, 13p

Prediction of pathological complete response after neoadjuvant chemotherapy for HER2-negative breast cancer patients with routine immunohistochemical markers.

Authors: Häberle, Lothar, Erber, Ramona, Gass, Paul, Hein, Alexander, Niklos, Melitta, Volz, Bernhard, Hack, Carolin C., Schulz-Wendtland, Rüdiger, Huebner, Hanna, Goossens, Chloë, Christgen, Matthias, Dörk, Thilo, Park-Simon, Tjoung-Won, Schneeweiss, Andreas, Untch, Michael, Nekljudova, Valentina, Loibl, Sibylle, Hartmann, Arndt, Beckmann, Matthias W., Fasching, Peter A.

Source: Breast Cancer Research; 1/24/2025, Vol. 27 Issue 1, p1-13, 13p

Subject Terms: NEOADJUVANT chemotherapy, CANCER prognosis, BREAST cancer prognosis, MEDICAL sciences, PROGRESSION-free survival

Impact of prolonged sepsis on neural and muscular components of muscle contractions in a mouse model

Authors: Goossens, Chloë, Weckx, Ruben, Derde, Sarah, Van Helleputte, Lawrence, Schneidereit, Dominik, Haug, Michael, Reischl, Barbara, Friedrich, Oliver, Van Den Bosch, Ludo, Van den Berghe, Greet, Langouche, Lies

Source: Journal of cachexia, sarcopenia and muscle. 12(2):443-455

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185483561.0x000001&indx=1&recIds=ETOCvdc_100185483561.0x000001

SEMPAI: a Self‐Enhancing Multi‐Photon Artificial Intelligence for Prior‐Informed Assessment of Muscle Function and Pathology

Authors: Mühlberg, Alexander, Ritter, Paul, Langer, Simon, Goossens, Chloë, Nübler, Stefanie, Schneidereit, Dominik, Taubmann, Oliver, Denzinger, Felix, Nörenberg, Dominik, Haug, Michael, Schürmann, Sebastian, Horstmeyer, Roarke, Maier, Andreas K., Goldmann, Wolfgang H., Friedrich, Oliver, Kreiss, Lucas

Source: Advanced science. 10(28)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195105895.0x000001&indx=1&recIds=ETOCvdc_100195105895.0x000001

Susceptibility gene mutations in germline and tumors of patients with HER2-negative advanced breast cancer.

Authors: Fasching, Peter A., Hu, Chunling, Hart, Steven N., Ruebner, Matthias, Polley, Eric C., Gnanaolivu, Rohan D., Hartkopf, Andreas D., Huebner, Hanna, Janni, Wolfgang, Hadji, Peyman, Tesch, Hans, Uhrig, Sabrina, Ettl, Johannes, Lux, Michael P., Lüftner, Diana, Wallwiener, Markus, Wurmthaler, Lena A., Goossens, Chloë, Müller, Volkmar, Beckmann, Matthias W.

Source: NPJ Breast Cancer; 7/13/2024, Vol. 10 Issue 1, p1-7, 7p

Adipose tissue protects against sepsis-induced muscle weakness in mice: from lipolysis to ketones

Authors: Goossens, Chloë, Weckx, Ruben, Derde, Sarah, Dufour, Thomas, Vander Perre, Sarah, Pauwels, Lies, Thiessen, Steven, Van Veldhoven, Paul, Van den Berghe, Greet, Langouche, Lies

Source: Critical care. 23(1):1-17

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189154123.0x000001&indx=1&recIds=ETOCvdc_100189154123.0x000001

Efficacy and safety of ketone ester infusion to prevent muscle weakness in a mouse model of sepsis-induced critical illness.

Authors: Weckx, Ruben¹ (AUTHOR), Goossens, Chloë¹ (AUTHOR), Derde, Sarah¹ (AUTHOR), Pauwels, Lies¹ (AUTHOR), Vander Perre, Sarah¹ (AUTHOR), Van den Berghe, Greet¹ (AUTHOR), Langouche, Lies¹ (AUTHOR) lies.langouche@kuleuven.be

Source: Scientific Reports. 6/22/2022, Vol. 12 Issue 1, p1-12. 12p.

Subject Terms: *LABORATORY mice, *CRITICALLY ill, *KETONES, *MUSCLE weakness, *ANIMAL disease models, *BOLUS drug administration, *SEPSIS, *BOLUS radiotherapy

Attrition in the First Three Therapy Lines in Patients with Advanced Breast Cancer in the German Real-World PRAEGNANT Registry.

Alternate Title: Real-World-Daten des deutschen PRAEGNANT-Registers zu Therapieabbrüchen der ersten 3 Therapielinien bei Patientinnen mit fortgeschrittenem Brustkrebs. (German)

Authors: Hartkopf, Andreas D., Walter, Christina B., Kolberg, Hans-Christian, Hadji, Peyman, Tesch, Hans, Fasching, Peter A., Ettl, Johannes, Lüftner, Diana, Wallwiener, Markus, Müller, Volkmar, Beckmann, Matthias W., Belleville, Erik, Huebner, Hanna, Uhrig, Sabrina, Goossens, Chloë, Link, Theresa, Hielscher, Carsten, Mundhenke, Christoph, Kurbacher, Christian, Wuerstlein, Rachel

Source: Geburtshilfe und Frauenheilkunde; May2024, Vol. 84 Issue 5, p459-469, 11p

Optimization of Endometrial Decidualization in the Menstruating Mouse Model for Preclinical Endometriosis Research

Authors: Peterse, Daniëlle, De Clercq, Katrien, Goossens, Chloë, Binda, M. Mercedes, Dorien, F. O., Saunders, Philippa, Vriens, Joris, Fassbender, Amelie, D Hooghe, Thomas M.

Source: Reproductive sciences. 25(11):1577-1588

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN617933479&indx=1&recIds=ETOCRN617933479

Role of Glucagon in Catabolism and Muscle Wasting of Critical Illness and Modulation by Nutrition

Authors: Thiessen, Steven E., Derde, Sarah, Derese, Inge, Dufour, Thomas, Vega, Chloé Albert, Langouche, Lies, Goossens, Chloë, Peersman, Nele, Vermeersch, Pieter, Vander Perre, Sarah

Source: American journal of respiratory and critical care medicine. 196(9):1131-1143

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN614556904&indx=1&recIds=ETOCRN614556904

Development of muscle weakness in a mouse model of critical illness: does fibroblast growth factor 21 play a role?

Authors: Vankrunkelsven, Wouter, Thiessen, Steven, Derde, Sarah, Vervoort, Ellen, Derese, Inge, Pintelon, Isabel, Matheussen, Hanne, Jans, Alexander, Goossens, Chloë, Langouche, Lies, Van den Berghe, Greet, Vanhorebeek, Ilse

Source: Skeletal Muscle; 11/18/2023, Vol. 13 Issue 1, p1-15, 15p

Subject Terms: FIBROBLAST growth factors, MUSCLE weakness, CRITICALLY ill, MUSCLE growth, LABORATORY mice

Effect of withholding early parenteral nutrition in PICU on ketogenesis as potential mediator of its outcome benefit

Authors: De Bruyn, Astrid, Gunst, Jan, Goossens, Chloë, Vander Perre, Sarah, Guerra, Gonzalo G., Verbruggen, Sascha, Joosten, Koen, Langouche, Lies, Van den Berghe, Greet

Source: Critical care. 24(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171990944.0x000001&indx=1&recIds=ETOCvdc_100171990944.0x000001

Identification of the toxic threshold of 3-hydroxybutyrate-sodium supplementation in septic mice.

Authors: Weckx, Ruben, Goossens, Chloë, Derde, Sarah, Pauwels, Lies, Vander Perre, Sarah, Van den Bergh, Greet, Langouche, Lies

Source: BMC Pharmacology & Toxicology; 9/20/2021, Vol. 22 Issue 1, p1-13, 13p

Subject Terms: LABORATORY mice, PARENTERAL feeding, MICE, PLACEBOS, LUNGS, ANTIBIOTICS

Altered cholesterol homeostasis in critical illness-induced muscle weakness: effect of exogenous 3-hydroxybutyrate.

Authors: Goossens, Chloë, Weckx, Ruben, Derde, Sarah, Vander Perre, Sarah, Derese, Inge, Van Veldhoven, Paul P., Ghesquière, Bart, Van den Berghe, Greet, Langouche, Lies

Source: Critical Care; 8/17/2021, Vol. 25 Issue 1, p1-12, 12p

Subject Terms: MICE physiology, CHOLESTEROL metabolism, HOMEOSTASIS, 3-Hydroxybutyric acid, BIOLOGICAL models, RESEARCH, MULTIVARIATE analysis, ANIMAL experimentation, RESEARCH methodology, GENETIC disorders, MEDICAL cooperation, EVALUATION research, MUSCLE weakness, CATASTROPHIC illness, COMPARATIVE studies, RESEARCH funding, LIPID metabolism disorders, CHOLESTEROL, MICE

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

Proliferation and differentiation of adipose tissue in prolonged lean and obese critically ill patients.

Authors: Goossens, Chloë¹, Vander Perre, Sarah¹, Van den Berghe, Greet¹, Langouche, Lies¹ lies.langouche@kuleuven.be

Source: Intensive Care Medicine Experimental. 3/16/2017, Vol. 5 Issue 1, p1-15. 15p.

Subject Terms: *ADIPOSE tissues, *CRITICALLY ill, *OVERWEIGHT persons, *ADIPOGENESIS, *EICOSANOIDS, *LABORATORY mice, *HEALTH