Phase II Randomized Trial of BI 730357, an Oral RORγt Inhibitor, for Moderate-to-Severe Plaque Psoriasis

Authors: Gooderham, Melinda J. ^{1, 2, 3, ∗}, Mrowietz, Ulrich ⁴, Kadus, Werner ⁵, Drda, Kristin ⁶, Gu, Hui ⁶, Vangerow, Harald ⁷, Flack, Mary ⁶, Korell, Julia ⁶, Sofen, Howard ⁸, Papp, Kim A. ^{2, 9, 10}

Source: In Journal of Investigative Dermatology December 2024

Long-term safety and effectiveness of roflumilast cream 0.3% in adults with chronic plaque psoriasis: A 52-week, phase 2, open-label trial

Authors: Stein Gold, Linda, Adam, David N., Albrecht, Lorne, Alonso-Llamazares, Javier, Ferris, Laura K., Gooderham, Melinda J., Hong, H. Chih-ho, Kempers, Steven E., Kircik, Leon H., Lebwohl, Mark, Loo, Wei Jing, Nahm, Walter K., Papp, Kim A., Stewart, Daniel, Toth, Darryl P., Zirwas, Matthew, Krupa, David, Snyder, Scott, Burnett, Patrick, Higham, Robert, Berk, David R.

Source: In Journal of the American Academy of Dermatology August 2024 91(2):273-280

Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials

Authors: Stein Gold, Linda, Lain, Edward, Del Rosso, James Q., Gold, Michael, Draelos, Zoe D., Eichenfield, Lawrence F., Sadick, Neil, Werschler, William P., Gooderham, Melinda J., Lupo, Mary

Source: In Journal of the American Academy of Dermatology November 2023 89(5):927-935

Treat-to-target in the management of moderate-to-severe atopic dermatitis in adults: A Canadian perspective

Authors: Yeung, Jensen, Gooderham, Melinda J., Hong, H. Chih-Ho, Lynde, Charles, Prajapati, Vimal H., Lansang, Perla, Turchin, Irina, Wiseman, Marni, Jack, Carolyn, Ramien, Michele, Purdy, Kerri, Grewal, Parbeer

Source: Journal of the American Academy of Dermatology. 89(2):372-375

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194201885.0x000001&indx=1&recIds=ETOCvdc_100194201885.0x000001

Triple‐combination clindamycin phosphate 1.2%/benzoyl peroxide 3.1%/adapalene 0.15% gel for moderate‐to‐severe acne in children and adolescents: Randomized phase 2 study

Authors: Eichenfield, Lawrence F., Stein Gold, Linda, Kircik, Leon H., Werschler, William P., Beer, Kenneth, Draelos, Zoe D., Tanghetti, Emil A., Papp, Kim A., Baldwin, Hilary, Lain, Edward, Sadick, Neil, Gooderham, Melinda J., Konda, Adarsh

Source: Pediatric dermatology. 40(3):452-459

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183678136.0x000001&indx=1&recIds=ETOCvdc_100183678136.0x000001

Clinical Implications of Targeting the JAK-STAT Pathway in Psoriatic Disease: Emphasis on the TYK2 Pathway

Authors: Loo, Wei Jing, Turchin, Irina, Prajapati, Vimal H., Gooderham, Melinda J., Grewal, Parbeer, Hong, Chih-ho, Sauder, Maxwell, Vender, Ronald B., Maari, Catherine, Papp, Kim A.

Source: Journal of cutaneous medicine and surgery. 27(lement 1):3S-24S

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631295770&indx=1&recIds=ETOCRN631295770

The Safety and Efficacy of Roflumilast Cream 0.15% and 0.05% in Patients With Atopic Dermatitis: Randomized, Double-Blind, Phase 2 Proof of Concept Study

Authors: Gooderham, Melinda J., Kircik, Leon H., Zirwas, Matthew, Lee, Mark, Kempers, Steven E., Draelos, Zoe D., Ferris, Laura K., Jones, Terry M., Proulx, Etienne Saint-Cyr, Bissonnette, Robert

Source: Journal of drugs in dermatology. 22(2):139-147

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631203782&indx=1&recIds=ETOCRN631203782

Considerations for defining and diagnosing generalized pustular psoriasis.

Authors: Prajapati, Vimal H., Lynde, Charles W., Gooderham, Melinda J., Hong, H. Chih‐ho, Kirchhof, Mark G., Lansang, Perla, Ringuet, Julien, Turchin, Irina, Vender, Ron, Yeung, Jensen, Papp, Kim A.

Source: Journal of the European Academy of Dermatology & Venereology; Mar2025, Vol. 39 Issue 3, p487-497, 11p

Subject Terms: PSORIASIS, DIAGNOSIS, ERYTHEMA, SYMPTOMS, SKIN diseases, PATHOGENESIS

Real‐world, long‐term treatment patterns of commonly used biologics in Canadian patients with moderate‐to‐severe chronic plaque psoriasis

Authors: Gooderham, Melinda J., Lynde, Charles, Turchin, Irina, Avadisian, Miriam, Labelle, Melanie, Papp, Kim A.

Source: Journal of dermatology. 49(1):95-105

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138730195.0x000001&indx=1&recIds=ETOCvdc_100138730195.0x000001

Real-World Moderate-to-Severe Hidradenitis Suppurativa: Decrease in Disease Burden With Adalimumab

Authors: Gulliver, Wayne, Alavi, Afsaneh, Wiseman, Marni C., Gooderham, Melinda J., Rao, Jaggi, Alam, Maryam Shayesteh, Papp, Kim A., Desjardins, Olivier, Jean, Christine

Source: Journal of cutaneous medicine and surgery. 26(4):361-370

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630001417&indx=1&recIds=ETOCRN630001417

Safety of Janus kinase (JAK) inhibitors in the short‐term treatment of atopic dermatitis

Authors: Wood, Hannah, Chandler, Antoinette, Nezamololama, Novin, Papp, Kim, Gooderham, Melinda J.

Source: International journal of dermatology. 61(6):746-754

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100151298728.0x000001&indx=1&recIds=ETOCvdc_100151298728.0x000001

Could it be gluten? Additional skin conditions associated with celiac disease

Authors: Klemm, Natasha, Gooderham, Melinda J., Papp, Kim

Source: International journal of dermatology. 61(1):33-38

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100147448077.0x000001&indx=1&recIds=ETOCvdc_100147448077.0x000001

Transition of Topical Therapy Formulation in Psoriasis: Insights from a Canadian Practice Reflective

Authors: Adam, David N., Abdulla, Sonya J., Fleming, Patrick, Gooderham, Melinda J., Ashkenas, John, McCracken, Clinton B.

Source: Skin therapy letter. 27(2):6-11

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN628845217&indx=1&recIds=ETOCRN628845217

Phosphodiesterase-4 Inhibition in the Management of Psoriasis.

Authors: Crowley, Erika L.¹ (AUTHOR) erikalc@student.ubc.ca, Gooderham, Melinda J.^2,3,4 (AUTHOR) mgooderham@centrefordermatology.com

Source: Pharmaceutics. Jan2024, Vol. 16 Issue 1, p23. 18p.

Subject Terms: *CYCLIC adenylic acid, *PHOSPHODIESTERASE inhibitors, *PSORIASIS, *CLINICAL trials, *APREMILAST

Effect of Ixekizumab on Patient Reported Outcomes and Quality of Life in Patients With Moderate-to-Severe Plaque Psoriasis: 5-Year Results from the UNCOVER-1 and -2 Studies

Authors: Gooderham, Melinda J., Elewski, Boni, Augustin, Matthias, Iversen, Lars, Torii, Hideshi, Burge, Russel, See, Kyoungah, Gallo, Gaia, Eastman, William J., McKean-Matthews, Missy

Source: Journal of drugs in dermatology. 20(4):394-401

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626290113&indx=1&recIds=ETOCRN626290113

Consistent response to guselkumab treatment between Hispanic and non-Hispanic patients with psoriasis: an analysis from VOYAGE 1 and VOYAGE 2

Authors: Puig, Luis, Wu, Jashin J., Gooderham, Melinda J., You, Yin, Shen, Yaung-Kaung, Randazzo, Bruce, Kerdel, Francisco

Source: Journal of dermatological treatment. 32(5):484-491

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122427927.0x000001&indx=1&recIds=ETOCvdc_100122427927.0x000001

Development and Content Validation of Pruritus and Symptoms Assessment for Atopic Dermatitis (PSAAD) in Adolescents and Adults with Moderate-to-Severe AD

Authors: Hall, Rebecca, Lebwohl, Mark G., Bushmakin, Andrew G., Simpson, Eric L., Gooderham, Melinda J., Wollenberg, Andreas, Gater, Adam, Wells, Jane R., Cappelleri, Joseph C., Hsu, Ming-Ann, Papacharalambous, Jocelyn, Peeva, Elena, Tallman, Anna M., Zhang, Weidong, Chen, Linda

Source: Dermatology and therapy. 11(1):221-233

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194078226.0x000001&indx=1&recIds=ETOCvdc_100194078226.0x000001

Real-world evidence on the benefits of optimal itch relief and skin clearance in atopic dermatitis management: a study from the TARGET-DERM AD registry.

Authors: Silverberg, Jonathan I., Calimlim, Brian M., Grada, Ayman, Bunick, Christopher G., Gooderham, Melinda J., Shi, Vivian Y., Obi, Chibuzo, Knapp, Keith D., Munoz, Breda, Crawford, Julie M., Paller, Amy S.

Source: Journal of Dermatological Treatment; Dec2024, Vol. 35 Issue 1, p1-7, 7p

Incidence and prognosis of COVID-19 in patients with atopic diseases on dupilumab: a multicentre retrospective cohort study

Authors: Rankin, Brian D., Georgakopoulos, Jorge-Ryan, Sachdeva, Muskaan, Mufti, Asfandyar, Devani, Alim R., Gooderham, Melinda J., Hong, Chih-Ho, Jain, Vipul, Lansang, Perla, Vender, Ronald, Yeung, Jensen, Prajapati, Vimal H.

Source: Journal of dermatological treatment. 33(5):2692-2694

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173033112.0x000001&indx=1&recIds=ETOCvdc_100173033112.0x000001

TYK2 inhibition: changing the treatment landscape for psoriasis?

Authors: Abduelmula, Abrahim, Gooderham, Melinda J.

Source: Expert review of clinical immunology. 18(3):185-187

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100145921230.0x000001&indx=1&recIds=ETOCvdc_100145921230.0x000001