Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway

Authors: Hannan, Katherine M., Soo, Priscilla, Wong, Mei S., Lee, Justine K., Hein, Nadine, Poh, Perlita, Wysoke, Kira D., Williams, Tobias D., Montellese, Christian, Smith, Lorey K., Al-Obaidi, Sheren J., Núñez-Villacís, Lorena, Pavy, Megan, He, Jin-Shu, Parsons, Kate M., Loring, Karagh E., Morrison, Tess, Diesch, Jeannine, Burgio, Gaetan, Ferreira, Rita, Feng, Zhi-Ping, Gould, Cathryn M., Madhamshettiwar, Piyush B., Flygare, Johan, Gonda, Thomas J., Simpson, Kaylene J., Kutay, Ulrike, Pearson, Richard B., Engel, Christoph, Watkins, Nicholas J., Hannan, Ross D., George, Amee J.

Source: In Cell Reports 1 November 2022 41(5)

Childhood acute myeloid leukemia shows a high level of germline predisposition

Authors: Samaraweera, Saumya E., Wang, Paul P.S., Li, Ka Leung, Casolari, Debora A., Feng, Jinghua, Pinese, Mark, Maung, Kyaw Ze Ya, Leo, Paul, Cowley, Mark, Perkins, Kelly, Smith, Amanda M., Ellis, Jonathan, Wee, Amilia, Hiwase, Devendra K., Scott, Hamish S., Schreiber, Andreas W., Brown, Anna L., Deans, Andrew J., Ross, David M., Moore, Andrew S., Gonda, Thomas J., Hahn, Christopher N., D'Andrea, Richard J.

Source: Blood. 138(22):2293-2298

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183247801.0x000001&indx=1&recIds=ETOCvdc_100183247801.0x000001

Genome-Wide Overexpression Screen Identifies Genes Able to Bypass p16-Mediated Senescence in Melanoma

Authors: Lee, Won Jae, Škalamera, Dubravka ^*, Dahmer-Heath, Mareike ^*, Shakhbazov, Konstanin, Ranall, Max V., Fox, Carly, Lambie, Duncan, Stevenson, Alexander J. ^*, Yaswen, Paul, Gonda, Thomas J., Gabrielli, Brian ^{*, **}

Source: In SLAS Discovery March 2017 22(3):298-308

Gateway-compatible vectors for high-throughput protein expression in pro- and eukaryotic cell-free systems

Authors: Gagoski, Dejan, Mureev, Sergey, Giles, Nichole, Johnston, Wayne, Dahmer-Heath, Mareike, Škalamera, Dubravka, Gonda, Thomas J., Alexandrov, Kirill

Source: In Journal of Biotechnology 10 February 2015 195:1-7

Rapid Mapping of Interactions between Human SNX-BAR Proteins Measured In Vitro by AlphaScreen and Single-molecule Spectroscopy

Authors: Sierecki, Emma ^{‡, **}, Stevers, Loes M. ^{‡, **}, Giles, Nichole ^‡, Polinkovsky, Mark E. ^‡, Moustaqil, Mehdi ^‡, Mureev, Sergey ^‡, Johnston, Wayne A. ^‡, Dahmer-Heath, Mareike ^§, Skalamera, Dubravka ^§, Gonda, Thomas J. ^¶, Gabrielli, Brian ^§, Collins, Brett M. ^‡, Alexandrov, Kirill ^{‡, ‖}, Gambin, Yann ^‡

Source: In Molecular & Cellular Proteomics September 2014 13(9):2233-2245

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes

Authors: Pattabiraman, Diwakar R., McGirr, Crystal, Shakhbazov, Konstantin, Barbier, Valerie, Krishnan, Keerthana, Mukhopadhyay, Pamela, Hawthorne, Paula, Trezise, Ann, Ding, Jianmin, Grimmond, Sean M., Papathanasiou, Peter, Alexander, Warren S., Perkins, Andrew C., Levesque, Jean-Pierre, Winkler, Ingrid G., Gonda, Thomas J.

Source: In Blood 24 April 2014 123(17):2682-2690

MYB down-regulation enhances sensitivity of U937 myeloid leukemia cells to the histone deacetylase inhibitor LBH589 in vitro and in vivo

Authors: Ye, Ping, Zhao, Liang, McGirr, Crystal, Gonda, Thomas J

Source: In Cancer Letters 1 February 2014 343(1):98-106

The MYB oncogene can suppress apoptosis in acute myeloid leukemia cells by transcriptional repression of DRAK2 expression

Authors: Ye, Ping, Zhao, Liang, Gonda, Thomas J.

Source: In Leukemia Research May 2013 37(5):595-601

Myb-binding Protein 1a (Mybbp1a) Regulates Levels and Processing of Pre-ribosomal RNA

Authors: Hochstatter, Julia, Hölzel, Michael, Rohrmoser, Michaela, Schermelleh, Lothar, Leonhardt, Heinrich, Keough, Rebecca ^**, Gonda, Thomas J., Imhof, Axel, Eick, Dirk, Längst, Gernot, Németh, Attila

Source: In Journal of Biological Chemistry July 2012 287(29):24365-24377

The GM-CSF receptor utilizes β-catenin and Tcf4 to specify macrophage lineage differentiation

Authors: Brown, Anna L., Salerno, Diana G., Sadras, Teresa, Engler, Grant A., Kok, Chung H., Wilkinson, Christopher R., Samaraweera, Saumya E., Sadlon, Timothy J., Perugini, Michelle, Lewis, Ian D., Gonda, Thomas J., D'Andrea, Richard J.

Source: In Differentiation 2012 83(1):47-59

Mechanism of and Requirement for Estrogen-Regulated MYB Expression in Estrogen-Receptor-Positive Breast Cancer Cells

Authors: Drabsch, Yvette, Hugo, Honor, Zhang, Rui, Dowhan, Dennis H., Miao, Yu Rebecca, Gewirtz, Alan M., Barry, Simon C., Ramsay, Robert G., Gonda, Thomas J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2007 Aug . 104(34), 13762-13767.

Access URL: https://www.jstor.org/stable/25436565

The mechanism of MYB transcriptional regulation by MLL-AF9 oncoprotein

Authors: Cao, Lu, Mitra, Partha, Gonda, Thomas J.

Source: Scientific reports. 9(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131393062.0x000001&indx=1&recIds=ETOCvdc_100131393062.0x000001

A recessive screen for genes regulating hematopoietic stem cells

Authors: Papathanasiou, Peter, Tunningley, Robert, Pattabiraman, Diwakar R., Ye, Ping, Gonda, Thomas J., Whittle, Belinda, Hamilton, Adam E., Cridland, Simon O., Lourie, Rohan, Perkins, Andrew C.

Source: In Blood 23 December 2010 116(26):5849-5858

Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common β-subunit

Authors: Perugini, Michelle, Brown, Anna L., Salerno, Diana G., Booker, Grant W., Stojkoski, Cvetan, Hercus, Timothy R., Lopez, Angel F., Hibbs, Margaret L., Gonda, Thomas J., D'Andrea, Richard J. ^*

Source: In Blood 22 April 2010 115(16):3346-3353

Delineation of Three Functional Domains of the Transcriptional Activator Encoded by the C-myb Protooncogene

Authors: Sakura, Hiroshi, Kanei-Ishii, Chie, Nagase, Takahiro, Nakagoshi, Hideki, Gonda, Thomas J., Ishii, Shunsuke

Source: Proceedings of the National Academy of Sciences of the United States of America, 1989 Aug 01. 86(15), 5758-5762.

Access URL: https://www.jstor.org/stable/34199

Transactivation and Transformation by Myb are Negatively Regulated by a Leucine-Zipper Structure

Authors: Kanei-Ishii, Chie, MacMillan, Elizabeth M., Nomura, Teruaki, Sarai, Akinori, Ramsay, Robert G., Aimoto, Saburo, Ishii, Shunsuke, Gonda, Thomas J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1992 Apr 01. 89(7), 3088-3092.

Access URL: https://www.jstor.org/stable/2359039

Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia

Authors: Maung, Kyaw Ze Ya, Leo, Paul J., Bassal, Mahmoud, Casolari, Debora A., Gray, James X, Bray, Sarah C., Pederson, Stephen, Singhal, Deepak, Samaraweera, Saumya E., Nguyen, Tran, Cildir, Gökhan, Marshall, Mhairi, Ewing, Adam, Duncan, Emma L., Brown, Matthew A., Saal, Russell, Tergaonkar, Vinay, To, Luen Bik, Marlton, Paula, Gill, Devinder, Lewis, Ian, Deans, Andrew J, Brown, Anna L, D'Andrea, Richard J, Gonda, Thomas J

Source: Blood cancer journal. 8(6)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100105150399.0x000001&indx=1&recIds=ETOCvdc_100105150399.0x000001

Partial reprogramming of heterologous cells by defined factors to generate megakaryocyte lineage-restricted biomolecules

Authors: Artuz, Crisbel M., Knights, Alexander J., Funnell, Alister P.W., Gonda, Thomas J., Ravid, Katya, Pearson, Richard C.M., Quinlan, Kate G.R., Crossley, Merlin

Source: Biotechnology reports. 20

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100073595436.0x000001&indx=1&recIds=ETOCvdc_100073595436.0x000001

Lack of reproducible growth inhibition by Schlafen1 and Schlafen2 in vitro

Authors: Zhao, Liang, Neumann, Brent, Murphy, Kathleen, Silke, John, Gonda, Thomas J.

Source: In Blood Cells, Molecules and Diseases 2008 41(2):188-193

DNA binding-independent transcriptional activation of the vascular endothelial growth factor gene ( VEGF) by the Myb oncoprotein

Authors: Lutwyche, Jodi K., Keough, Rebecca A., Hunter, Julie, Coles, Leeanne S., Gonda, Thomas J.

Source: In Biochemical and Biophysical Research Communications 2006 344(4):1300-1307