Phenotypic quantification of Nphs1-deficient mice.

Authors: Schneider, Ronen, Mansour, Bshara, Kolvenbach, Caroline M., Buerger, Florian, Salmanullah, Daanya, Lemberg, Katharina, Merz, Lea M., Mertens, Nils D., Saida, Ken, Yousef, Kirollos, Franken, Gijs A. C., Bao, Aaron, Yu, Seyoung, Hölzel, Selina, Nicolas-Frank, Camille, Steinsapir, Andrew, Goncalves, Kevin A., Shril, Shirlee, Hildebrandt, Friedhelm

Source: Journal of Nephrology (JNonline); Jan2025, Vol. 38 Issue 1, p143-152, 10p

Single-dose MGTA-145/plerixafor leads to efficient mobilization and in vivo transduction of HSCs with thalassemia correction in mice

Authors: Li, Chang, Goncalves, Kevin A., Raskó, Tamás, Pande, Amit, Gil, Sucheol, Liu, Zhinan, Izsvák, Zsuzsanna, Papayannopoulou, Thalia, Davis, John C., Jr, Kiem, Hans-Peter, Lieber, André ^*

Source: In Blood Advances 9 March 2021 5(5):1239-1249

Plexin-B2 Mediates Physiologic and Pathologic Functions of Angiogenin

Authors: Yu, Wenhao, Goncalves, Kevin A., Li, Shuping, Kishikawa, Hiroko, Sun, Guangjie, Yang, Hailing, Vanli, Nil, Wu, Yunxia, Jiang, Yuxiang, Hu, Miaofen G., Friedel, Roland H., Hu, Guo-fu

Source: In Cell 2 November 2017 171(4):849-864

Quantitative phenotyping of Nphs1 knockout mice as a prerequisite for gene replacement studies.

Authors: Buerger, Florian, Merz, Lea M., Saida, Ken, Seyoung Yu, Salmanullah, Daanya, Lemberg, Katharina, Mertens, Nils D., Mansour, Bshara, Kolvenbach, Caroline M., Yousef, Kirollos, Hölzel, Selina, Braun, Alina, Franken, Gijs A. C., Goncalves, Kevin A., Steinsapir, Andrew, Endlich, Nicole, Schneider, Ronen, Shril, Shirlee, Hildebrandt, Friedhelm

Source: American Journal of Physiology: Renal Physiology; May2024, Vol. 326 Issue 5, pF780-F791, 12p

Subject Terms: KNOCKOUT mice, SERUM albumin, BLOOD urea nitrogen, NEPHROTIC syndrome, CHRONIC kidney failure, RENAL tubular transport disorders, GENE targeting, PEDIATRIC nephrology

Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators

Authors: Silberstein, Lev, Goncalves, Kevin A., Kharchenko, Peter V., Turcotte, Raphael, Kfoury, Youmna, Mercier, Francois, Baryawno, Ninib, Severe, Nicolas, Bachand, Jacqueline, Spencer, Joel A., Papazian, Ani, Lee, Dongjun, Chitteti, Brahmananda Reddy, Srour, Edward F., Hoggatt, Jonathan, Tate, Tiffany, Lo Celso, Cristina, Ono, Noriaki, Nutt, Stephen, Heino, Jyrki, Sipilä, Kalle, Shioda, Toshihiro, Osawa, Masatake, Lin, Charles P., Hu, Guo-fu, Scadden, David T.

Source: In Cell Stem Cell 6 October 2016 19(4):530-543

Angiogenin Promotes Hematopoietic Regeneration by Dichotomously Regulating Quiescence of Stem and Progenitor Cells

Authors: Goncalves, Kevin A., Silberstein, Lev, Li, Shuping, Severe, Nicolas, Hu, Miaofen G., Yang, Hailing, Scadden, David T., Hu, Guo-fu

Source: In Cell 11 August 2016 166(4):894-906

Quantitative phenotyping of Nphs1knockout mice as a prerequisite for gene replacement studies

Authors: Buerger, Florian, Merz, Lea M., Saida, Ken, Yu, Seyoung, Salmanullah, Daanya, Lemberg, Katharina, Mertens, Nils D., Mansour, Bshara, Kolvenbach, Caroline M., Yousef, Kirollos, Hölzel, Selina, Braun, Alina, Franken, Gijs A. C., Goncalves, Kevin A., Steinsapir, Andrew, Endlich, Nicole, Schneider, Ronen, Shril, Shirlee, Hildebrandt, Friedhelm

Source: American Journal of Physiology - Renal Physiology; May 2024, Vol. 326 Issue: 5 pF780-F791, 12p

Gabapentin hybrid peptides and bioconjugates

Authors: Lebedyeva, Iryna O., Ostrov, David A., Neubert, John, Steel, Peter J., Patel, Kunal, Sileno, Sean M., Goncalves, Kevin, Ibrahim, Mohamed A., Alamry, Khalid A., Katritzky, Alan R.

Source: In Bioorganic & Medicinal Chemistry 15 February 2014 22(4):1479-1486

Phenotypic quantification of Nphs1-deficient mice

Authors: Schneider, Ronen, Mansour, Bshara, Kolvenbach, Caroline M., Buerger, Florian, Salmanullah, Daanya, Lemberg, Katharina, Merz, Lea M., Mertens, Nils D., Saida, Ken, Yousef, Kirollos, Franken, Gijs A. C., Bao, Aaron, Yu, Seyoung, Hölzel, Selina, Nicolas-Frank, Camille, Steinsapir, Andrew, Goncalves, Kevin A., Shril, Shirlee, Hildebrandt, Friedhelm

Source: Journal of Nephrology; 20240101, Issue: Preprints p1-10, 10p

Chemosensitization of prostate cancer stem cells in mice by angiogenin and plexin-B2 inhibitors

Authors: Li, Shuping, Goncalves, Kevin A., Lyu, Baiqing, Yuan, Liang, Hu, Guo-fu

Source: Communications biology. 3(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130041756.0x000001&indx=1&recIds=ETOCvdc_100130041756.0x000001

Mechanism and Function of Angiogenin in Hematopoietic Malignancy (in English)

Authors: Goncalves, Kevin A., Hu, Guo-Fu

Source: Zhongguo sheng wu hua xue yu fen zi sheng wu xue bao. 31(12):1267-1275

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN605427235&indx=1&recIds=ETOCRN605427235

Mgta-145 + Plerixafor Provides GCSF-Free Rapid and Reliable Hematopoietic Stem Cell Mobilization for Autologous Stem Cell Transplant in Patients with Multiple Myeloma: A Phase 2 Study

Authors: Sidana, Surbhi, Bankova, Andriyana K., Hosoya, Hitomi, Kumar, Shaji, Tamaresis, John, Le, Anne, Muffly, Lori, Johnston, Laura, Arai, Sally, Lowsky, Robert, Meyer, Everett H., Rezvani, Andrew R., Weng, Wen-Kai, Frank, Matthew J., Shiraz, Parveen, Girgenti, Douglas, Goncalves, Kevin A., Schmelmer, Veit, Davis, John, Lu, Ying, Shizuru, Judith A., Miklos, David B.

Source: Transplantation and Cellular Therapy. 28(S):S73-S73

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157891593.0x000001&indx=1&recIds=ETOCvdc_100157891593.0x000001

Differential Expression and Function of Peroxiredoxin 1 and Peroxiredoxin 6 in Cancerous MCF-7 and Noncancerous MCF-10A Breast Epithelial Cells

Authors: Goncalves, Kevin, Sullivan, Katie, Phelan, Shelley

Source: Cancer investigation. 30(1):38-47

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103608046.0x000001&indx=1&recIds=ETOCvdc_100103608046.0x000001

High Dose Hematopoietic Stem Cell Transplantation Leads to Rapid Neural and Peripheral Disease Cross-Correction Via Robust Hematopoietic and Microglia Recovery

Authors: Goncalves, Kevin A., Hyzy, Sharon L., Brooks, Melissa L., Hertzler, Hans J., Boitano, Anthony E., Cooke, Michael P.

Source: Biology of blood and marrow transplantation. 26(S):S207-S208

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100100241908.0x000001&indx=1&recIds=ETOCvdc_100100241908.0x000001

Mgta-145 and Plerixafor-Mediated HSC Mobilization Along with HDAd5/35++ Vector into Mice Allows for Efficient In Vivo HSC Transduction and Stable Gene Marking in Peripheral Blood Cells

Authors: Li, Chang, Goncalves, Kevin A., Davis, John C, Kiem, Hans-Peter, Lieber, Andre

Source: Transplantation and Cellular Therapy. 27(S):S15-S15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100134294695.0x000001&indx=1&recIds=ETOCvdc_100134294695.0x000001

MGTA-145, in Combination with Plerixafor in a Phase 1 Clinical Study, Mobilizes Large Numbers of Hematopoietic Stem Cells and a Graft with Potent Immunosuppressive Properties for Autologous and Allogeneic Transplant

Authors: Goncalves, Kevin A., Hyzy, Sharon L., Hammond, Katelyn J., Falahee, Patrick C., Howell, Haley, Pinkas, Jan, Schmelmer, Veit, Hoggatt, Jonathan G., Scadden, David T., Devine, Steven M., DiPersio, John F., Savage, William J., Davis, John C

Source: Transplantation and Cellular Therapy. 27(S):S34-S34

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100134294655.0x000001&indx=1&recIds=ETOCvdc_100134294655.0x000001

Phase 2 study of MGTA-145 + plerixafor for rapid and reliable hematopoietic stem cell (HSC) mobilization for autologous transplant in multiple myeloma.

Authors: Sidana, Surbhi, Bankova, Andriyana, Hosoya, Hitomi, Muffly, Lori S., Kumar, Shaji, Johnston, Laura J., Lowsky, Robert, Meyer, Everett, Rezvani, Andrew, Weng, Wen-Kai, Arai, Sally, Frank, Matthew Joshua, Shiraz, Parveen, Howell, Haley, Goncalves, Kevin A, Schmelmer, Veit, Davis, John, Shizuru, Judith, Miklos, David Bernard

Source: Journal of clinical oncology. 39(15 suppl):8023-8023

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173216942.0x000001&indx=1&recIds=ETOCvdc_100173216942.0x000001

Angiogenin and plexin-B2 axis promotes glioblastoma progression by enhancing invasion, vascular association, proliferation and survival.

Authors: Yang, Hailing, Yuan, Liang, Ibaragi, Soichiro, Li, Shuping, Shapiro, Robert, Vanli, Nil, Goncalves, Kevin A., Yu, Wenhao, Kishikawa, Hiroko, Jiang, Yuxiang, Hu, Alexander J., Jay, Daniel, Cochran, Brent, Holland, Eric C., Hu, Guo-fu

Source: British Journal of Cancer; Aug2022, Vol. 127 Issue 3, p422-435, 14p

Subject Terms: NERVE tissue proteins, ANIMAL experimentation, GLIOMAS, CELL physiology, CELL adhesion molecules, RESEARCH funding, CELL lines, ESTERASES, ANIMALS, MICE

Mgta-456 Contains Large Numbers of CD34+CD90+ Hematopoietic Stem Cells (HSC) Which Contain the NSG Engraftment Activity and Correlate with Time to Neutrophil Recovery Following Transplant into Patients with Hematologic Malignancy

Authors: Boitano, Anthony E., Goncalves, Kevin A., Sumstad, Darin, Wagner, John E., Cooke, Michael P.

Source: Biology of blood and marrow transplantation. 25(S):S2-S3

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117313284.0x000001&indx=1&recIds=ETOCvdc_100117313284.0x000001

Mgta-456, a First-in-Class Cell Therapy with High Doses of CD34+CD90+ Cells, Enhances Speed and Level of Human Microglia Engraftment in the Brains of NSG Mice

Authors: Goncalves, Kevin A., Li, Shuping, Brooks, Melissa, Hyzy, Sharon L., Boitano, Anthony E., Cooke, Michael P.

Source: Biology of blood and marrow transplantation. 25(S):S92-S93

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117308411.0x000001&indx=1&recIds=ETOCvdc_100117308411.0x000001