MAP17 promotes an epithelial-mesenchymal-amoeboid transition in hepatocellular carcinoma by switching one-carbon metabolism

Authors: Gil-Pitarch, Claudia, Uriarte, Iker, Bertran, Esther, Hermán-Sánchez, Natalia, García-Heredia, José Manuel, Agudo, Rubén Rodríguez, Goikoetxea, Naroa, Lachiondo-Ortega, Sofia, Mercado-Gómez, Maria, González-Recio, Irene, Delgado, Teresa Cardoso, Vivanco, Maria, Martinez-Cruz, Luis Alfonso, Martín, Cesar Augusto, Artuch, Rafael, Fernández, Mario, Ortiz, Manuel Gahete, Fabregat, Isabel, Avila, Matías A, Carnero, Amancio, Martínez-Chantar, María Luz

Source: Journal of hepatology. 78(S1):S529-S530

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195505096.0x000001&indx=1&recIds=ETOCvdc_100195505096.0x000001

Silencing CNNM4 in cholangiocarcinoma inhibits tumoral progression by means of non-canonical ferroptosis

Authors: Mercado-Gómez, Maria, Giné, Alvaro Eguilero, Bravo, Miren, Azkargorta, Mikel, Serrano-Macia, Marina, Goikoetxea, Naroa, González-Recio, Irene, Lachiondo-Ortega, Sofia, Gil-Pitarch, Claudia, Romero, Marta, Omella, Judit Domenech, Agudo, Rubén Rodríguez, Zapata-Pavas, Leidy Estefanía, Felix, Patricia Peña-San, Olaizola, Paula, Rodrigues, Pedro Miguel, Martinez-Cruz, Luis Alfonso, Lamarca, Angela, Moreno, Victor, Banales, Jesus Maria, Delgado, Teresa Cardoso, Elortza, Felix, Avila, Matías A, Cubero, Francisco Javier, Martín, Cesar Augusto, Merlos Rodrigo, Miguel Angel, Calvisi, Diego, Marin, Jose, Martínez-Chantar, María Luz

Source: Journal of hepatology. 78(S1):S544-S545

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195504941.0x000001&indx=1&recIds=ETOCvdc_100195504941.0x000001

Metabolic rewiring by increased mitochondrial respiration drives immunosuppression in liver cancer

Authors: Goikoetxea, Naroa, Egia-Mendikute, Leire, Bravo, Miren, Serrano-Macia, Marina, Delgado, Teresa Cardoso, Ladero, Iraia, Molina, Elena, Lachiondo-Ortega, Sofia, Agudo, Rubén Rodríguez, Castelo, Janire, Barriales, Diego, Iruretagoyena, Begoña Rodriguez, Santamaria, Eva, Mercado-Gómez, Maria, González-Recio, Irene, Rincón, Mercedes, Avila, Matías A, Anguita, Juan, Elguezabal, Natalia, Palazón, Asís, Martínez-Chantar, María Luz

Source: Journal of hepatology. 78(S1):S532-S532

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195505067.0x000001&indx=1&recIds=ETOCvdc_100195505067.0x000001

Pediatric liver cancer: Hepatoblastoma and Neddylation post-translational modification

Authors: Zapata-Pavas, Leidy Estefanía, Serrano-Macia, Marina, Merlos Rodrigo, Miguel Angel, Felix, Patricia Peña-San, Gil-Pitarch, Claudia, Goikoetxea, Naroa, Michalkova, Hana, Heger, Zbynek, del Rio, Alvaro, Domingo-Sàbat, Montserrat, Royo, Laura, Barrenechea-Barrenechea, Jon Ander, Mercado-Gómez, Maria, Lachiondo-Ortega, Sofia, Delgado, Teresa Cardoso, Xirodimas, Dimitris, Marin, Jose, Fernandez-Barrena, Maite G, Avila, Matías A, Armengol, Carolina, Martínez-Chantar, María Luz

Source: Journal of hepatology. 78(S1):S546-S546

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195504948.0x000001&indx=1&recIds=ETOCvdc_100195504948.0x000001

Senescence, hand in hand with hepatic iron overload during the progression of NAFLD

Authors: Bravo, Miren, Simón, Jorge, Goikoetxea, Naroa, Lachiondo-Ortega, Sofia, Egia-Mendikute, Leire, Maus, Mate, Pelusi, Serena, Amengual, Josep, Gonzalez-Sanchez, Ester, Vaquero, Javier, Nogueiras, Ruben, Palazón, Asís, Valenti, Luca, Fabregat, Isabel, Serrano, Manuel, Martínez-Chantar, María Luz

Source: Journal of hepatology. 77(S1):S673-S674

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167006632.0x000001&indx=1&recIds=ETOCvdc_100167006632.0x000001

Methionine adenosyltransferase 1a antisense oligonucleotides induce the fibroblast growth factor 21-driven recovery from obesity and associated hepatoesteatosis

Authors: Buque, Xabier, de Urturi, Diego Saenz, Porteiro, Begoña, Folgueira, Cintia, Mora, Alfonso, Delgado, Teresa Cardoso, Prieto-Fernández, Endika, Olaizola, Paula, Santos, Beatriz Gómez, Apodaka-Biguri, Maider, Gonzalez-Romero, Francisco, Nieva-Zuluaga, Ane, de Gauna, Mikel Ruiz, Goikoetxea, Naroa, García Rodríguez, Juan Luis, de Juan, Virginia Gutiérrez, Aurrekoetxea, Igor, Montalvo-Romeral, Valle, Novoa, Eva, Martin-Guerrero, Idoia, Varela-Rey, Marta, Bhanot, Sanjay, Lee, Richard, Banales, Jesus Maria, Syn, Wing-Kin, Sabio, Guadalupe, Martínez-Chantar, María Luz, Nogueiras, Ruben, Aspichueta, Patricia

Source: Journal of hepatology. 77(S1):S689-S690

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167004826.0x000001&indx=1&recIds=ETOCvdc_100167004826.0x000001

Magnesium modulation by CNNM4 silencing in DIAMOND mice via GalNAc-siRNA therapy: a new and effective therapeutic approach against MAFLD

Authors: Agudo, Rubén Rodríguez, Goikoetxea, Naroa, Bravo, Miren, Lachiondo-Ortega, Sofia, Serrano-Macia, Marina, Mercado-Gómez, Maria, Fondevila, Marcos Fernandez, Delgado, Teresa Cardoso, Martinez-Cruz, Luis Alfonso, Martin-Bermudo, Franz, Nogueiras, Ruben, Martín, Cesar Augusto, Schaeper, Ute, Buccella, Daniela, Simón, Jorge, Martínez-Chantar, María Luz

Source: Journal of hepatology. 77(S1):S87-S88

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167070139.0x000001&indx=1&recIds=ETOCvdc_100167070139.0x000001

Human antigen R (HuR) is a master regulator of hepatic glucose metabolism

Authors: Lachiondo-Ortega, Sofia, Bravo, Miren, González-Recio, Irene, González Rellán, María J., Espinosa, Jorge Simón, Goikoetxea, Naroa, Petrov, Petar, Agudo, Rubén Rodríguez, Sanz-Parra, Arantza, Iruretagoyena, Begoña Rodriguez, Delgado, Teresa Cardoso, Dixon, Dan A., Gorospe, Myriam, Nogueiras, Ruben, Martínez-Chantar, María Luz

Source: Journal of hepatology. 77(S1):S84-S85

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167070612.0x000001&indx=1&recIds=ETOCvdc_100167070612.0x000001

Targeting cyclin M4 as a new therapeutical approach to treat alcoholic liver disease

Authors: González-Recio, Irene, Goikoetxea, Naroa, Agudo, Rubén Rodríguez, Espinosa, Jorge Simón, Serrano-Macia, Marina, Azkargorta, Mikel, Elortza, Felix, Diaz-Moreno, Irene, Diaz-Quintana, Antonio, Schaeper, Ute, Bataller, Ramon, Avila, Matías A, Martinez-Cruz, Luis Alfonso, Martínez-Chantar, María Luz

Source: Journal of hepatology. 77(S1):S132-S133

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167066329.0x000001&indx=1&recIds=ETOCvdc_100167066329.0x000001

Mitochondrial hyperactivation determines a transferable protective gut microbiota profile in metabolic-associated fatty liver disease development

Authors: Juárez-Fernández, María, Goikoetxea, Naroa, Porras, David, García-Mediavilla, María-Victoria, Rodríguez, Héctor, Nistal, Esther, Martínez-Flórez, Susana, Rincón, Mercedes, Varela-Rey, Marta, González-Gállego, Javier, Abecia, Leticia, Anguita, Juan, Martínez-Chantar, María Luz, Sánchez-Campos, Sonia

Source: Journal of hepatology. 77(S1):S177-S178

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167062663.0x000001&indx=1&recIds=ETOCvdc_100167062663.0x000001

Magnesium accumulation by CNNM4 GalNAc-siRNA mediated silencing reduces cholestasis-associated liver fibrosis

Authors: Serrano-Macia, Marina, Goikoetxea, Naroa, Agudo, Rubén Rodríguez, Bravo, Miren, Lachiondo-Ortega, Sofia, Fondevila, Marcos Fernandez, Petrov, Petar, González-Recio, Irene, Mercado-Gómez, Maria, Gil-Pitarch, Claudia, Romero, Marta, Delgado, Teresa Cardoso, Martinez-Cruz, Luis Alfonso, Nogueiras, Ruben, Martin, Cesar, Milkiewicz, Piotr, Milkiewicz, Malgorzata, Schaeper, Ute, Buccella, Daniela, Marin, Jose Juan G., Espinosa, Jorge Simón, Martínez-Chantar, María Luz

Source: Journal of hepatology. 77(S1):S600-S600

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167012749.0x000001&indx=1&recIds=ETOCvdc_100167012749.0x000001

Targeting liver glutaminase 1 modulates hepatic ammonia in experimental Non-Alcoholic Steatohepatitis

Authors: Mercado-Gómez, Maria, Goikoetxea, Naroa, Serrano-Macia, Marina, Lachiondo-Ortega, Sofia, Agudo, Rubén Rodríguez, Petrov, Petar, Bravo, Miren, Gil-Pitarch, Claudia, González-Recio, Irene, Espinosa, Jorge Simón, Martínez-Chantar, María Luz, Delgado, Teresa Cardoso

Source: Journal of hepatology. 77(S1):S679-S679

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167006246.0x000001&indx=1&recIds=ETOCvdc_100167006246.0x000001

MAP17 promotes metastasis in hepatocellular carcinoma by modulating the epithelial-mesenchymal-amoeboid transition

Authors: Gil-Pitarch, Claudia, Bertran, Esther, Uriarte, Iker, Hermán-Sánchez, Natalia, García-Heredia, José Manuel, Goikoetxea, Naroa, Serrano-Macia, Marina, Agudo, Rubén Rodríguez, Lachiondo-Ortega, Sofia, Mercado-Gómez, Maria, Rábano, Miriam, Delgado, Teresa Cardoso, Espinosa, Jorge Simón, Martinez-Cruz, Luis Alfonso, Martín, Cesar Augusto, Vivanco, Maria, Avila, Matías A., Ortiz, Manuel Gahete, Fabregat, Isabel, Carnero, Amancio, Martínez-Chantar, María Luz

Source: Journal of hepatology. 77(S1):S48-S48

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167076633.0x000001&indx=1&recIds=ETOCvdc_100167076633.0x000001

Novel therapy with anti-miR-873-5p at late stages of acetaminophen overdose

Authors: Agudo, Rubén Rodríguez, Fernández-Tussy, Pablo, Ballesteros, Gorka, Ramos, David Fernández, Otsoa, Fernando Lopitz, Simón, Jorge, Mabe, Jon, Blanco, Laura Moran, Goikoetxea, Naroa, Serrano-Macia, Marina, Lachiondo-Ortega, Sofia, Mercado-Gómez, Maria, Bizkarguenaga, Maider, de Juan, Virginia Gutiérrez, González-Recio, Irene, Varela-Rey, Marta, Cubero, Francisco Javier, Mato, José M., Andrade, Raul J., Lucena, Maria Isabel, Martinez-Cruz, Luis Alfonso, Delgado, Teresa Cardoso, Martínez-Chantar, María Luz

Source: Journal of hepatology. 73(S1):S232-S233

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100120844874.0x000001&indx=1&recIds=ETOCvdc_100120844874.0x000001

NEDD8 specific protease 1 (NEDP1) as a tumor suppressor in hepatocellular carcinoma

Authors: Serrano-Macia, Marina, Bailly, Aymeric, Perrin, Aurelien, Chantal, Maghames, Leidecker, Orsolya, Trauchessec, Helene, Goikoetxea, Naroa, Agudo, Rubén Rodríguez, Lachiondo-Ortega, Sofia, Gartner, Anton, Delgado, Teresa Cardoso, Xirodimas, Dimitris, Martińez-Chantar, Mariá Luz

Source: Journal of hepatology. 73(S1):S644-S645

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100120837241.0x000001&indx=1&recIds=ETOCvdc_100120837241.0x000001

SAT-247 - Pediatric liver cancer: Hepatoblastoma and Neddylation post-translational modification

Authors: Zapata-Pavas, Leidy Estefanía, Serrano-Macia, Marina, Merlos Rodrigo, Miguel Angel, Felix, Patricia Peña-San, Gil-Pitarch, Claudia, Goikoetxea, Naroa, Michalkova, Hana, Heger, Zbynek, del Rio, Alvaro, Domingo-Sàbat, Montserrat, Royo, Laura, Barrenechea-Barrenechea, Jon Ander, Mercado-Gómez, Maria, Lachiondo-Ortega, Sofia, Delgado, Teresa Cardoso, Xirodimas, Dimitris, Marin, Jose, Fernandez-Barrena, Maite G, Avila, Matías A, Armengol, Carolina, Martínez-Chantar, María Luz

Source: In Journal of Hepatology June 2023 78 Supplement 1:S546-S546

SAT-244 - Silencing CNNM4 in cholangiocarcinoma inhibits tumoral progression by means of non-canonical ferroptosis

Authors: Mercado-Gómez, Maria, Giné, Alvaro Eguilero, Bravo, Miren, Azkargorta, Mikel, Serrano-Macia, Marina, Goikoetxea, Naroa, González-Recio, Irene, Lachiondo-Ortega, Sofia, Gil-Pitarch, Claudia, Romero, Marta, Omella, Judit Domenech, Agudo, Rubén Rodríguez, Zapata-Pavas, Leidy Estefanía, Felix, Patricia Peña-San, Olaizola, Paula, Rodrigues, Pedro Miguel, Martinez-Cruz, Luis Alfonso, Lamarca, Angela, Moreno, Victor, Banales, Jesus Maria, Delgado, Teresa Cardoso, Elortza, Felix, Avila, Matías A, Cubero, Francisco Javier, Martín, Cesar Augusto, Merlos Rodrigo, Miguel Angel, Calvisi, Diego, Marin, Jose, Martínez-Chantar, María Luz

Source: In Journal of Hepatology June 2023 78 Supplement 1:S544-S545

SAT-221 - Metabolic rewiring by increased mitochondrial respiration drives immunosuppression in liver cancer

Authors: Goikoetxea, Naroa, Egia-Mendikute, Leire, Bravo, Miren, Serrano-Macia, Marina, Delgado, Teresa Cardoso, Ladero, Iraia, Molina, Elena, Lachiondo-Ortega, Sofia, Agudo, Rubén Rodríguez, Castelo, Janire, Barriales, Diego, Iruretagoyena, Begoña Rodriguez, Santamaria, Eva, Mercado-Gómez, Maria, González-Recio, Irene, Rincón, Mercedes, Avila, Matías A, Anguita, Juan, Elguezabal, Natalia, Palazón, Asís, Martínez-Chantar, María Luz

Source: In Journal of Hepatology June 2023 78 Supplement 1:S532-S532

SAT-216 - MAP17 promotes an epithelial-mesenchymal-amoeboid transition in hepatocellular carcinoma by switching one-carbon metabolism

Authors: Gil-Pitarch, Claudia, Uriarte, Iker, Bertran, Esther, Hermán-Sánchez, Natalia, García-Heredia, José Manuel, Agudo, Rubén Rodríguez, Goikoetxea, Naroa, Lachiondo-Ortega, Sofia, Mercado-Gómez, Maria, González-Recio, Irene, Delgado, Teresa Cardoso, Vivanco, Maria, Martinez-Cruz, Luis Alfonso, Martín, Cesar Augusto, Artuch, Rafael, Fernández, Mario, Ortiz, Manuel Gahete, Fabregat, Isabel, Avila, Matías A, Carnero, Amancio, Martínez-Chantar, María Luz

Source: In Journal of Hepatology June 2023 78 Supplement 1:S529-S530

FRI-399 - Neddylation inhibition recovers drug-induced liver injury through the stabilization of Tamm41

Authors: Gil-Pitarch, Claudia, Serrano-Macia, Marina, Espinosa, Jorge Simón, Agudo, Rubén Rodríguez, Lachiondo-Ortega, Sofia, Mercado-Gómez, Maria, González-Recio, Irene, Goikoetxea, Naroa, Delgado, Teresa Cardoso, Martinez-Cruz, Luis Alfonso, Nogueiras, Ruben, Iruzubieta, Paula, Crespo, Javier, Masson, Steven, McCain, Misti, Reeves, Helen Louise, Martínez-Chantar, María Luz

Source: In Journal of Hepatology June 2023 78 Supplement 1:S140-S140