Baseline immune state and T-cell clonal kinetics are associated with durable response to CAR-T therapy in large B-cell lymphoma

Authors: Maurer, Katie ^{1, 2, 3}, Grabski, Isabella N. ⁴, Houot, Roch ^{1, 5}, Gohil, Satyen H. ^{1, 6, 7}, Miura, Shogo ¹, Redd, Robert ⁴, Lyu, Haoxiang ^{1, 8}, Lu, Wesley ^{1, 8}, Arihara, Yohei ¹, Budka, Justin ⁹, McDonough, Mikaela ¹, Ansuinelli, Michela ¹, Reynolds, Carol ¹, Jacene, Heather ^{2, 10}, Li, Shuqiang ^{1, 3, 8}, Livak, Kenneth J. ^{1, 8}, Ritz, Jerome ^{1, 2}, Miles, Brodie ⁹, Mattie, Mike ⁹, Neuberg, Donna S. ¹¹, Irizarry, Rafael A. ^{4, 11}, Armand, Philippe ^{1, 2}, Wu, Catherine J. ^{1, 2, 3}, Jacobson, Caron ^{1, 2, ∗}

Source: In Blood 12 December 2024 144(24):2490-2502

Oncogenomics in the classification of mature B-and T-cell lymphomas: where are we now?

Authors: Gohil, Satyen, Pomplun, Sabine

Source: In Diagnostic Histopathology August 2024 30(8):457-465

Acquired Glanzmann's thrombasthenia with IgG and IgA against activated αIIbβ3

Authors: Constantinescu‐Bercu, Adela, McCann, Sabina, Hmaid, Amjad, Groot, Rens, Singh, Deepak, Gohil, Satyen H., Thomas, Mari, Scully, Marie, Westwood, John‐Paul

Source: British journal of haematology. 202(6):e58-e61

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192107078.0x000001&indx=1&recIds=ETOCvdc_100192107078.0x000001

ZNF683 marks a CD8+ T cell population associated with anti-tumor immunity following anti-PD-1 therapy for Richter syndrome

Authors: Parry, Erin M., Lemvigh, Camilla K., Deng, Stephanie, Dangle, Nathan, Ruthen, Neil, Knisbacher, Binyamin A., Broséus, Julien, Hergalant, Sébastien, Guièze, Romain, Li, Shuqiang, Zhang, Wandi, Johnson, Connor, Long, Jaclyn M., Yin, Shanye, Werner, Lillian, Anandappa, Annabelle, Purroy, Noelia, Gohil, Satyen, Oliveira, Giacomo, Bachireddy, Pavan, Shukla, Sachet A., Huang, Teddy, Khoury, Joseph D., Thakral, Beenu, Dickinson, Michael, Tam, Constantine, Livak, Kenneth J., Getz, Gad, Neuberg, Donna, Feugier, Pierre, Kharchenko, Peter, Wierda, William, Olsen, Lars Rønn, Jain, Nitin, Wu, Catherine J.

Source: In Cancer Cell 9 October 2023 41(10):1803-1816

The immune microenvironment shapes transcriptional and genetic heterogeneity in chronic lymphocytic leukemia

Authors: Sun, Clare ^∗, Chen, Yun-Ching, Martinez Zurita, Aina, Baptista, Maria Joao, Pittaluga, Stefania, Liu, Delong, Rosebrock, Daniel, Gohil, Satyen Harish, Saba, Nakhle S., Davies-Hill, Theresa, Herman, Sarah E. M., Getz, Gad, Pirooznia, Mehdi, Wu, Catherine J., Wiestner, Adrian ^∗∗

Source: In Blood Advances 10 January 2023 7(1):145-158

Single-cell analysis reveals immune dysfunction from the earliest stages of CLL that can be reversed by ibrutinib

Authors: Purroy, Noelia, Tong, Yuzhou Evelyn, Lemvigh, Camilla K., Cieri, Nicoletta, Li, Shuqiang, Parry, Erin M., Zhang, Wandi, Rassenti, Laura Z., Kipps, Thomas J., Slager, Susan L., Kay, Neil E., Lesnick, Connie, Shanafelt, Tait D., Ghia, Paolo, Scarfò, Lydia, Livak, Kenneth J., Kharchenko, Peter V., Neuberg, Donna S., Olsen, Lars Rønn, Fan, Jean, Gohil, Satyen H., Wu, Catherine J.

Source: Blood. 139(14):2252-2256

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183256005.0x000001&indx=1&recIds=ETOCvdc_100183256005.0x000001

Patients undergoing multiligament knee reconstruction injured during pivoting sports demonstrate similar clinical, functional and return to sport outcomes by 2 years compared with those undergoing anterior cruciate ligament reconstruction.

Authors: Ebert, Jay R., Edwards, Peter K., Mayne, Alistair I. W., Davies, Peter S. E., Evans, Robert, Aujla, Randeep S., Malik, Shahbaz S., Dalgleish, Stephen, Gohil, Satyen, D'Alessandro, Peter

Source: Knee Surgery, Sports Traumatology, Arthroscopy; Mar2025, Vol. 33 Issue 3, p865-877, 13p

Coevolving JAK2V617F+relapsed AML and donor T cells with PD-1 blockade after stem cell transplantation: an index case

Authors: Penter, Livius, Gohil, Satyen H., Huang, Teddy, Thrash, Emily M., Schmidt, Dominik, Li, Shuqiang, Severgnini, Mariano, Neuberg, Donna, Hodi, F. Stephen, Livak, Kenneth J., Zeiser, Robert, Bachireddy, Pavan ^{*, *}, Wu, Catherine J. ^*

Source: In Blood Advances 23 November 2021 5(22):4701-4709

Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy

Authors: Bachireddy, Pavan, Azizi, Elham, Burdziak, Cassandra, Nguyen, Vinhkhang N., Ennis, Christina S., Maurer, Katie, Park, Cameron Y., Choo, Zi-Ning, Li, Shuqiang, Gohil, Satyen H., Ruthen, Neil G., Ge, Zhongqi, Keskin, Derin B., Cieri, Nicoletta, Livak, Kenneth J., Kim, Haesook T., Neuberg, Donna S., Soiffer, Robert J., Ritz, Jerome, Alyea, Edwin P., Pe’er, Dana, Wu, Catherine J.

Source: In Cell Reports 9 November 2021 37(6)

Clonal hematopoiesis in patients receiving chimeric antigen receptor T-cell therapy

Authors: Miller, Peter G. ^*, Sperling, Adam S. ^*, Brea, Elliott J., Leick, Mark B., Fell, Geoffrey G., Jan, Max, Gohil, Satyen H., Tai, Yu-Tzu, Munshi, Nikhil C., Wu, Catherine J., Neuberg, Donna S., Maus, Marcela V., Jacobson, Caron, Gibson, Christopher J., Ebert, Benjamin L. ^*

Source: In Blood Advances 10 August 2021 5(15):2982-2986

Progressive immune dysfunction with advancing disease stage in renal cell carcinoma

Authors: Braun, David A., Street, Kelly, Burke, Kelly P., Cookmeyer, David L., Denize, Thomas, Pedersen, Christina B., Gohil, Satyen H., Schindler, Nicholas, Pomerance, Lucas, Hirsch, Laure, Bakouny, Ziad, Hou, Yue, Forman, Juliet, Huang, Teddy, Li, Shuqiang, Cui, Ang, Keskin, Derin B., Steinharter, John, Bouchard, Gabrielle, Sun, Maxine, Pimenta, Erica M., Xu, Wenxin, Mahoney, Kathleen M., McGregor, Bradley A., Hirsch, Michelle S., Chang, Steven L., Livak, Kenneth J., McDermott, David F., Shukla, Sachet A., Olsen, Lars R., Signoretti, Sabina, Sharpe, Arlene H., Irizarry, Rafael A., Choueiri, Toni K., Wu, Catherine J.

Source: In Cancer Cell 10 May 2021 39(5):632-648

A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation

Authors: Lazarian, Gregory, Yin, Shanye, ten Hacken, Elisa, Sewastianik, Tomasz, Uduman, Mohamed, Font-Tello, Alba, Gohil, Satyen H., Li, Shuqiang, Kim, Ekaterina, Joyal, Heather, Billington, Leah, Witten, Elizabeth, Zheng, Mei, Huang, Teddy, Severgnini, Mariano, Lefebvre, Valerie, Rassenti, Laura Z., Gutierrez, Catherine, Georgopoulos, Katia, Ott, Christopher J., Wang, Lili, Kipps, Thomas J., Burger, Jan A., Livak, Kenneth J., Neuberg, Donna S., Baran-Marszak, Fanny, Cymbalista, Florence, Carrasco, Ruben D., Wu, Catherine J.

Source: In Cancer Cell 8 March 2021 39(3):380-393

Low seropositivity and suboptimal neutralisation rates in patients fully vaccinated against COVID‐19 with B‐cell malignancies

Authors: Fox, Thomas A., Kirkwood, Amy A., Enfield, Louise, O'Reilly, Maeve, Arulogun, Suzanne, D'Sa, Shirley, O'Nions, Jenny, Kavi, Janki, Vitsaras, Evan, Townsend, William, Burns, Siobhan O., Gohil, Satyen H., Cwynarski, Kate, Thomson, Kirsty J., Noursadeghi, Mahdad, Heyderman, Robert S., Rampling, Tommy, Ardeshna, Kirit M., McCoy, Laura E., Morris, Emma C.

Source: British journal of haematology. 195(5):706-709

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135305869.0x000001&indx=1&recIds=ETOCvdc_100135305869.0x000001

Modern multiligament knee injury surgical reconstruction techniques can achieve excellent knee function and patient satisfaction, with low complication rates.

Authors: Mayne, Alistair I. W., Ebert, Jay R., Edwards, Peter K., Davies, Peter S. E., Evans, Robert, Aujla, Randeep S., Malik, Shahbaz S., Grant, Michael J., Dalgleish, Stephen, Gohil, Satyen, D'Alessandro, Peter

Source: Knee Surgery, Sports Traumatology, Arthroscopy; Nov2024, Vol. 32 Issue 11, p2967-2977, 11p

Subject Terms: SPORTS re-entry, KNEE dislocation, PATIENT satisfaction, SPORTS participation, PLASTIC surgery

Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy

Authors: Bachireddy, Pavan, Azizi, Elham, Burdziak, Cassandra, Nguyen, Vinhkhang N., Ennis, Christina S., Maurer, Katie, Park, Cameron Y., Choo, Zi-Ning, Li, Shuqiang, Gohil, Satyen H., Ruthen, Neil G., Ge, Zhongqi, Keskin, Derin B., Cieri, Nicoletta, Livak, Kenneth J., Kim, Haesook T., Neuberg, Donna S., Soiffer, Robert J., Ritz, Jerome, Alyea, Edwin P., Pe'er, Dana, Wu, Catherine J.

Source: Cell reports. 42(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196442688.0x000001&indx=1&recIds=ETOCvdc_100196442688.0x000001

Coalescing and satellite erythematous papules on the calves and thighs of a middle-aged man.

Authors: Choudhary, Cherry, Kloczko, Ewa, Spencer, Ashley, McNamara, Christopher, Gohil, Satyen, Semkova, Kristina, Ong, Eugene, Proctor, Ian, Tung, Hsiu, Calonje, Eduardo, Bunker, Christopher B

Source: Clinical & Experimental Dermatology; Jan2025, Vol. 50 Issue 1, p214-216, 3p

Subject Terms: POSITRON emission tomography computed tomography, BLOOD cell count, NON-langerhans-cell histiocytosis, LANGERHANS-cell histiocytosis, MYELOID cells

In trans early mosaic mutational escape and novel phenotypic features of germline SAMD9 mutation

Authors: Hockings, Catherine, Gohil, Satyen, Dowse, Robin, Hoade, Yvette, Mansour, Marc R., Gale, Rosemary E., Linch, David C., Rao, Anupama, Payne, Elspeth M.

Source: British journal of haematology. 188(4):e53-e57

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100102894220.0x000001&indx=1&recIds=ETOCvdc_100102894220.0x000001

Dissecting CLL through high-dimensional single-cell technologies

Authors: Gohil, Satyen H., Wu, Catherine J. ^*

Source: In Blood 28 March 2019 133(13):1446-1456

The drill wobble effect: oversizing the femoral tunnel during ACL reconstruction

Authors: Cunningham, Gregory, Martineau, Paul A., Gohil, Satyen

Source: Physician and sportsmedicine. 46(1):44-47

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107002853.0x000001&indx=1&recIds=ETOCvdc_100107002853.0x000001

LenD: a study to establish the safety and efficacy of lenalidomide and dexamethasone in patients with relapsed or refractory chronic lymphocytic leukemia

Authors: Gohil, Satyen Harish, Maciocia, Nicola, Patrick, Pip, Roberts, Thomas, Counsell, Nicholas, Smith, Paul, Clifton-Hadley, Laura, Cwynarski, Kate, Pettitt, Andrew, Nathwani, Amit Chunilal

Source: Leukemia & lymphoma. 59(7):1730-1733

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100064573055.0x000001&indx=1&recIds=ETOCvdc_100064573055.0x000001