Opportunistic genomic screening has clinical utility: An interventional cohort study

Authors: Bombard, Yvonne, Armel, Susan Randall, Aronson, Melyssa, Baxter, Nancy N., Bond, Kenneth, Capo-Chichi, José-Mario, Carroll, June C., Caulfield, Timothy, Clausen, Marc, Clifford, Tammy J., Cohn, Iris, Dhalla, Irfan, Earle, Craig C., Eisen, Andrea, Elser, Christine, Evans, Michael, Glogowski, Emily, Graham, Tracy, Greenfeld, Elena, Hamilton, Jada G., Isaranuwatchai, Wanrudee, Kastner, Monika, Kim, Raymond H., Lerner-Ellis, Jordan, Morel, Chantal F., Mujoomdar, Michelle, Noor, Abdul, Offit, Kenneth, Panchal, Seema, Robson, Mark E., Scherer, Stephen W., Scheer, Adena, Schrader, Kasmintan A., Sullivan, Terrence, Thorpe, Kevin E., Mighton, Chloe ^{1, 2}, Kodida, Rita ², Shickh, Salma ^{1, 2}, Reble, Emma ², Sam, Jordan ², Grewal, Sonya ², Hirjikaka, Daena ², Piccinin, Carolyn ^{3, 4}, Ward, Thomas ⁵, Hofstedter, Renee ⁶, Mancuso, Talia ⁷, Forster, Nicole ⁸, Glogowksi, Emily ¹⁶, Chan, Kelvin K.W. ^{1, 19}

Source: In Genetics in Medicine February 2025 27(2)

Genetics Adviser: The development and usability testing of a new patient digital health application to support clinical genomic testing

Authors: Clausen, Marc, Krishnapillai, Suvetha, Hirjikaka, Daena, Kodida, Rita, Shickh, Salma, Reble, Emma, Mighton, Chloe, Sam, Jordan, Adi-Wauran, Ella, Baxter, Nancy N., Feldman, Geoff, Glogowski, Emily, Lerner-Ellis, Jordan, Scheer, Adena, Shastri-Estrada, Serena, Shuman, Cheryl, Armel, Susan Randall, Aronson, Melyssa, Graham, Tracy, Panchal, Seema, Thorpe, Kevin E., Carroll, June C., Eisen, Andrea, Elser, Christine, Kim, Raymond H., Faghfoury, Hanna, Schrader, Kasmintan A., Seto, Emily, Bombard, Yvonne

Source: In Genetics in Medicine Open 2024 2

“I don’t need any more unknowns hanging over my head”: Views of patients with cancer on variants of uncertain significance and low/moderate risk results from genomic sequencing

Authors: Bombard, Yvonne, Armel, Susan Randall, Aronson, Melyssa, Baxter, Nancy N., Bond, Kenneth, Capo-Chichi, José-Mario, Carroll, June C., Caulfield, Timothy, Clausen, Marc, Clifford, Tammy J., Cohn, Iris, Dhalla, Irfan, Earle, Craig C., Eisen, Andrea, Elser, Christine, Evans, Michael, Glogowski, Emily, Graham, Tracy, Greenfeld, Elena, Hamilton, Jada G., Isaranuwatchai, Wanrudee, Kastner, Monika, Kim, Raymond H., Laupacis, Andreas, Lerner-Ellis, Jordan, Morel, Chantal F., Mujoomdar, Michelle, Noor, Abdul, Offit, Kenneth, Panchal, Seema, Robson, Mark E., Scherer, Stephen W., Scheer, Adena, Schrader, Kasmintan A., Sullivan, Terrence, Thorpe, Kevin E., Shickh, Salma, Mighton, Chloe, Kodida, Rita, Adi-Wauran, Ella, Hirjikaka, Daena, Krishnapillai, Suvetha, Reble, Emma, Sam, Jordan

Source: In Genetics in Medicine December 2023 25(12)

How do members of the public expect to use variants of uncertain significance in their health care? A population-based survey

Authors: Mighton, Chloe, Clausen, Marc, Shickh, Salma, Baxter, Nancy N., Scheer, Adena, Sebastian, Agnes, Muir, Sarah M., Kim, Theresa H.M., Glogowski, Emily, Schrader, Kasmintan A., Regier, Dean A., Kim, Raymond H., Lerner-Ellis, Jordan, Bayoumi, Ahmed M., Thorpe, Kevin E., Bombard, Yvonne

Source: In Genetics in Medicine May 2023 25(5)

The role of digital tools in the delivery of genomic medicine: enhancing patient-centered care

Authors: Shickh, Salma, Rafferty, Sara A., Clausen, Marc, Kodida, Rita, Mighton, Chloe, Panchal, Seema, Lorentz, Justin, Ward, Thomas, Watkins, Nicholas, Elser, Christine, Eisen, Andrea, Carroll, June C., Glogowski, Emily, Schrader, Kasmintan A., Lerner-Ellis, Jordan, Kim, Raymond H., Chitayat, David, Shuman, Cheryl, Bombard, Yvonne, Armel, Susan, Aronson, Melyssa, Baxter, Nancy, Bond, Kenneth, Capo-Chichi, José-Mario, Caulfield, Timothy, Clifford, Tammy, Cohn, Iris, Dhalla, Irfan, Earle, Craig C., Evans, Mike, Graham, Tracy, Hamilton, Jada G., Isaranuwatchai, Wanrudee, Kastner, Monika, Laupacis, Andreas, Morel, Chantal F., Mujoomdar, Michelle, Offit, Kenneth, Robson, Mark E., Scheer, Adena, Scherer, Stephen W., Sullivan, Terrence, Thorpe, Kevin E.

Source: In Genetics in Medicine June 2021 23(6):1086-1094

Effectiveness of the Genomics ADvISER decision aid for the selection of secondary findings from genomic sequencing: a randomized clinical trial

Authors: Bombard, Yvonne, Clausen, Marc, Shickh, Salma, Mighton, Chloe, Casalino, Selina, Kim, Theresa H.M., Muir, Sarah M., Carlsson, Lindsay, Baxter, Nancy, Scheer, Adena, Elser, Christine, Eisen, Andrea, Panchal, Seema, Graham, Tracy, Aronson, Melyssa, Piccinin, Carolyn, Mancuso, Talia, Semotiuk, Kara, Evans, Michael, Carroll, June C., Offit, Kenneth, Robson, Mark, Hamilton, Jada G., Glogowski, Emily, Schrader, Kasmintan, Kim, Raymond H., Lerner-Ellis, Jordan, Thorpe, Kevin E., Laupacis, Andreas, Armel, Susan, Bayoumi, Ahmed, Bond, Ken, Caulfield, Timothy, Clifford, Tammy, Cohn, Iris, Dhalla, Irfan, Earle, Craig C., Isaranuwatchai, Wanrudee, Kastner, Monika, Mujoomdar, Michelle, Robson, Mark E., Scherer, Stephen W., Sullivan, Terrence

Source: In Genetics in Medicine April 2020 22(4):727-735

PARC report: a perspective on the state of clinical pharmacogenomics testing

Authors: Eichmeyer, Jennifer, Rogers, Sara, Formea, Christine M, Giri, Jyothsna, Jones, J Shawn, Schnettler, Erica, Schmidlen, Tara, Glogowski, Emily, Kurz, Raluca N

Source: Pharmacogenomics. 21(11):809-820

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186604045.0x000001&indx=1&recIds=ETOCvdc_100186604045.0x000001

PARC report: a health-systems focus on reimbursement and patient access to pharmacogenomics testing

Authors: L Rogers, Sara, Keeling, Nicholas J, Giri, Jyothsna, Gonzaludo, Nina, Jones, J Shawn, Glogowski, Emily, Formea, Christine M

Source: Pharmacogenomics. 21(11):785-796

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186574873.0x000001&indx=1&recIds=ETOCvdc_100186574873.0x000001

Development of patient 'profiles' to tailor counseling for incidental genomic sequencing results

Authors: Mighton, Chloe, Carlsson, Lindsay, Clausen, Marc, Casalino, Selina, Shickh, Salma, McCuaig, Laura, Joshi, Esha, Panchal, Seema, Graham, Tracy, Aronson, Melyssa, Piccinin, Carolyn, Winter-Paquette, Laura, Semotiuk, Kara, Lorentz, Justin, Mancuso, Talia, Ott, Karen, Silberman, Yael, Elser, Christine, Eisen, Andrea, Kim, Raymond, Lerner-Ellis, Jordan, Carroll, June, Glogowski, Emily, Schrader, Kasmintan, Bombard, Yvonne

Source: European journal of human genetics. 27(7):1008-1017

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181197079.0x000001&indx=1&recIds=ETOCvdc_100181197079.0x000001

P555: Clinical utility returning of all types of medically relevant genomic sequencing findings: An observational study

Authors: Mighton, Chloe, Kodida, Rita, Shickh, Salma, Clausen, Marc, Reble, Emma, Sam, Jordan, Grewal, Sonya, Panchal, Seema, Aronson, Melyssa, Armel, Susan, Graham, Tracy, Forster, Nicole, Capo-Chichi, Jose-Mario, Greenfeld, Elena, Noor, Abdul, Cohn, Iris, Morel, Chantal, Elser, Christine, Eisen, Andrea, Carroll, June, Glogowski, Emily, Schrader, Kasmintan, Chan, Kelvin, Thorpe, Kevin, Lerner-Ellis, Jordan, Kim, Raymond, Bombard, Yvonne

Source: In Genetics in Medicine Open 2024 2 Supplement 1

P538: Curious but cautious: Patients’ preferences for all types of clinically actionable genomic incidental results

Authors: Shickh, Salma, Kodida, Rita, Mighton, Chloe, Clausen, Marc, Reble, Emma, Sam, Jordan, Grewal, Sonya, Panchal, Seema, Aronson, Melyssa, Armel, Susan, Graham, Tracy, Elser, Christine, Eisen, Andrea, Carroll, June, Glogowski, Emily, Schrader, Kasmintan, Thorpe, Kevin, Lerner-Ellis, Jordan, Kim, Raymond, Bombard, Yvonne

Source: In Genetics in Medicine Open 2024 2 Supplement 1

P523: Returning all clinically relevant findings from genomic sequencing: Preliminary results from the incidental genomics RCT

Authors: Bombard, Yvonne, Mighton, Chloe, Shickh, Salma, Clausen, Marc, Kodida, Rita, Reble, Emma, Sam, Jordan, Grewal, Sonya, Panchal, Seema, Aronson, Melyssa, Armel, Susan, Graham, Tracy, Forster, Nicole, Capo-Chichi, Jose-Mario, Greenfeld, Elena, Noor, Abdul, Cohn, Iris, Morel, Chantal, Elser, Christine, Eisen, Andrea, Carroll, June, Glogowski, Emily, Schrader, Kasmintan, Lerner-Ellis, Jordan, Kim, Raymond, Thorpe, Kevin

Source: In Genetics in Medicine Open 2024 2 Supplement 1

The Genomics ADvISER: development and usability testing of a decision aid for the selection of incidental sequencing results

Authors: Bombard, Yvonne, Clausen, Marc, Mighton, Chloe, Carlsson, Lindsay, Casalino, Selina, Glogowski, Emily, Schrader, Kasmintan, Evans, Michael, Scheer, Adena, Baxter, Nancy, Hamilton, Jada, Lerner-Ellis, Jordan, Offit, Kenneth, Robson, Mark, Laupacis, Andreas

Source: European journal of human genetics. 26(7):984-995

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127960371.0x000001&indx=1&recIds=ETOCvdc_100127960371.0x000001

A model for the return and referral of all clinically significant secondary findings of genomic sequencing.

Authors: Kodida, Rita, Reble, Emma, Clausen, Marc, Shickh, Salma, Mighton, Chloe, Sam, Jordan, Forster, Nicole, Pancha, Seema, Aronson, Melyssa, Semotiuk, Kara, Graham, Tracy, Silberman, Yael, Armel, Susan Randall, McCuaig, Jeanna M., Cohn, Iris, Morel, Chantal F., Elser, Christine, Eisen, Andrea, Carroll, June C., Glogowski, Emily

Source: Journal of Medical Genetics; Aug2023, Vol. 60 Issue 8, p733-739, 7p

Great expectations: patients' preferences for clinically significant results from genomic sequencing.

Authors: Shickh, Salma, Sebastian, Agnes, Clausen, Marc, Mighton, Chloe, Elser, Christine, Eisen, Andrea, Waldman, Larissa, Panchal, Seema, Ward, Thomas, Carroll, June C., Glogowski, Emily, Schrader, Kasmintan A., Lerner-Ellis, Jordan, Kim, Raymond H., Thorpe, Kevin E., Bombard, Yvonne, the Incidental Genomics Team members to be indexed in PubMed, Armel, Susan R., Aronson, Melyssa, Baxter, Nancy N.

Source: Human Genetics; Apr2023, Vol. 142 Issue 4, p553-562, 10p

Subject Terms: PATIENT preferences, MONOGENIC & polygenic inheritance (Genetics), NEUROLOGICAL disorders, RARE diseases, SEQUENTIAL analysis, LOGISTIC regression analysis

Prospective Immunohistochemical Analysis of Primary Colorectal Cancers for Loss of Mismatch Repair Protein Expression

Authors: Lee-Kong, Steven A., Markowitz, Arnold J., Glogowski, Emily, Papadopoulos, Christopher, Stadler, Zsofia, Weiser, Martin R., Temple, Larissa K., Guillem, José G.

Source: In Clinical Colorectal Cancer 2010 9(4):255-259

Outcome of genetic evaluation of patients with kidney cancer referred for suspected hereditary cancer syndromes

Authors: Stratton, Kelly L., Alanee, Shaheen, Glogowski, Emily A., Schrader, Kasmintan A., Rau-Murthy, Rohini, Klein, Robert, Russo, Paul, Coleman, Jonathan, Offit, Kenneth

Source: In Urologic Oncology: Seminars and Original Investigations May 2016 34(5):238-238

Opportunistic genomic screening has clinical utility: An interventional cohort study

Authors: Mighton, Chloe, Kodida, Rita, Shickh, Salma, Clausen, Marc, Reble, Emma, Sam, Jordan, Grewal, Sonya, Hirjikaka, Daena, Panchal, Seema, Piccinin, Carolyn, Aronson, Melyssa, Ward, Thomas, Armel, Susan Randall, Hofstedter, Renee, Graham, Tracy, Mancuso, Talia, Forster, Nicole, Capo-Chichi, José-Mario, Greenfeld, Elena, Noor, Abdul, Cohn, Iris, Morel, Chantal F., Elser, Christine, Eisen, Andrea, Carroll, June C., Glogowksi, Emily, Schrader, Kasmintan A., Chan, Kelvin K.W., Thorpe, Kevin E., Lerner-Ellis, Jordan, Kim, Raymond H., Bombard, Yvonne, Bombard, Yvonne, Armel, Susan Randall, Aronson, Melyssa, Baxter, Nancy N., Bond, Kenneth, Capo-Chichi, José-Mario, Carroll, June C., Caulfield, Timothy, Clausen, Marc, Clifford, Tammy J., Cohn, Iris, Dhalla, Irfan, Earle, Craig C., Eisen, Andrea, Elser, Christine, Evans, Michael, Glogowski, Emily, Graham, Tracy, Greenfeld, Elena, Hamilton, Jada G., Isaranuwatchai, Wanrudee, Kastner, Monika, Kim, Raymond H., Lerner-Ellis, Jordan, Morel, Chantal F., Mujoomdar, Michelle, Noor, Abdul, Offit, Kenneth, Panchal, Seema, Robson, Mark E., Scherer, Stephen W., Scheer, Adena, Schrader, Kasmintan A., Sullivan, Terrence, Thorpe, Kevin E.

Source: Genetics in Medicine; February 2025, Vol. 27 Issue: 2

A636P is associated with early-onset colon cancer in Ashkenazi Jews

Authors: Guillem, José G, Rapaport, Beth S, Kirchhoff, Tomas, Kolachana, Prema, Nafa, Khedoudja, Glogowski, Emily, Finch, Rob, Huang, Helen, Foulkes, William D, Markowitz, Arnold, Ellis, Nathan A, Offit, Kenneth

Source: In Journal of the American College of Surgeons 2003 196(2):222-225

Patient and public preferences for being recontacted with updated genomic results: a mixed methods study.

Authors: Mighton, Chloe, Clausen, Marc, Sebastian, Agnes, Muir, Sarah M., Shickh, Salma, Baxter, Nancy N., Scheer, Adena, Glogowski, Emily, Schrader, Kasmintan A., Thorpe, Kevin E., Kim, Theresa H. M., Lerner-Ellis, Jordan, Kim, Raymond H., Regier, Dean A., Bayoumi, Ahmed M., Bombard, Yvonne

Source: Human Genetics; Dec2021, Vol. 140 Issue 12, p1695-1708, 14p

Subject Terms: PATIENT preferences, LOGISTIC regression analysis, ONLINE databases, MEDICAL personnel, WILLINGNESS to pay