Ionizing radiation and photodynamic therapy lead to multimodal tumor cell death, synergistic cytotoxicity and immune cell invasion in human bladder cancer organoids

Authors: Reinhold, Annabell ^a, Glasow, Annegret ^b, Nürnberger, Sandra ^a, Weimann, Annett ^a, Telemann, Lucie ^c, Stolzenburg, Jens-Uwe ^c, Neuhaus, Jochen ^a, Berndt-Paetz, Mandy ^{a, ⁎}

Source: In Photodiagnosis and Photodynamic Therapy February 2025 51

Rapid and reproducible generation of glioblastoma spheroids for high-throughput drug screening.

Authors: Bach, Christian, Glasow, Annegret, Baran-Schmidt, Rainer, Oppermann, Henry, Bach, Christoph, Meixensberger, Jürgen, Güresir, Erdem, Gaunitz, Frank

Source: Frontiers in Bioengineering & Biotechnology; 2025, p1-13, 13p

Imidazolyl Ethanamide Pentandioic Acid (IEPA) as Potential Radical Scavenger during Tumor Therapy in Human Hematopoietic Stem Cells.

Authors: Pfau, Lucas C.¹ (AUTHOR), Glasow, Annegret¹ (AUTHOR), Seidel, Clemens¹ (AUTHOR), Patties, Ina¹ (AUTHOR) ina.patties@medizin.uni-leipzig.de

Source: Molecules. Mar2023, Vol. 28 Issue 5, p2008. 22p.

Subject Terms: *HUMAN stem cells, *HEMATOPOIETIC stem cells, *DOUBLE-strand DNA breaks, *HEAD & neck cancer, *REACTIVE oxygen species, *THROMBOPOIETIN receptors, *CANCER stem cells, *IDIOPATHIC femoral necrosis

Enhanced anti-tumor effects by combination of tucatinib and radiation in HER2-overexpressing human cancer cell lines.

Authors: Amrell, Lukas, Bär, Eric, Glasow, Annegret, Kortmann, Rolf-Dieter, Seidel, Clemens, Patties, Ina

Source: Cancer Cell International; 8/6/2024, Vol. 24 Issue 1, p1-15, 15p

Subject Terms: NON-small-cell lung carcinoma, HER2 positive breast cancer, DOUBLE-strand DNA breaks, PROTEIN-tyrosine kinase inhibitors, DNA repair

Harnessing macrophages in thermal and non-thermal ablative therapies for urologic cancers – Potential for immunotherapy

Authors: Arthanareeswaran, Vinodh-Kumar-Adithyaa, Berndt-Paetz, Mandy, Ganzer, Roman, Stolzenburg, Jens-Uwe, Ravichandran-Chandra, Abinaya, Glasow, Annegret, Neuhaus, Jochen

Source: In Laparoscopic, Endoscopic and Robotic Surgery June 2018 1(1):5-11

Carnosine increases efficiency of temozolomide and irradiation treatment of isocitrate dehydrogenase-wildtype glioblastoma cells in culture

Authors: Dietterle, Johannes, Oppermann, Henry, Glasow, Annegret, Neumann, Karsten, Meixensberger, Jürgen, Gaunitz, Frank

Source: Future oncology. 15(32):3683-3691

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186820503.0x000001&indx=1&recIds=ETOCvdc_100186820503.0x000001

D, l-Methadone does not improve radio- and chemotherapy in glioblastoma in vitro

Authors: Oppermann, Henry, Matusova, Martina, Glasow, Annegret, Dietterle, Johannes, Baran-Schmidt, Rainer, Neumann, Karsten, Meixensberger, Jürgen, Gaunitz, Frank

Source: Cancer chemotherapy and pharmacology. 83(6):1017-1024

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125389929.0x000001&indx=1&recIds=ETOCvdc_100125389929.0x000001

Influence of low dose irradiation on differentiation, maturation and T-cell activation of human dendritic cells

Authors: Jahns, Jutta, Anderegg, Ulf, Saalbach, Anja, Rosin, Britt, Patties, Ina, Glasow, Annegret, Kamprad, Manja, Scholz, Markus, Hildebrandt, Guido

Source: In Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis 2011 709:32-39

The Chk1 inhibitor SAR-020106 sensitizes human glioblastoma cells to irradiation, to temozolomide, and to decitabine treatment

Authors: Patties, Ina, Kallendrusch, Sonja, Böhme, Lisa, Kendzia, Eva, Oppermann, Henry, Gaunitz, Frank, Kortmann, Rolf-Dieter, Glasow, Annegret

Source: Journal of experimental & clinical cancer research. 38(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129329335.0x000001&indx=1&recIds=ETOCvdc_100129329335.0x000001

Retinoids and myelomonocytic growth factors cooperatively activate RARΑ and induce human myeloid leukemia cell differentiation via MAP kinase pathways

Authors: Glasow, Annegret, Prodromou, Natalia, Xu, Ke, von Lindern, Marieke, Zelent, Arthur

Source: In Blood 1 January 2005 105(1):341-349

Immunomodulatory Effects by Photodynamic Treatment of Glioblastoma Cells In Vitro.

Authors: Rothe, Friederike, Patties, Ina, Kortmann, Rolf-Dieter, Glasow, Annegret

Source: Molecules; Jun2022, Vol. 27 Issue 11, p3384-3384, 20p

Subject Terms: PHOTODYNAMIC therapy, BONE marrow cells, CYTOTOXIC T cells, CELL death, GLIOBLASTOMA multiforme, IONIZING radiation, TREATMENT effectiveness

Enhanced Survival of High-Risk Medulloblastoma-Bearing Mice after Multimodal Treatment with Radiotherapy, Decitabine, and Abacavir.

Authors: Gringmuth, Marieke, Walther, Jenny, Greiser, Sebastian, Toussaint, Magali, Schwalm, Benjamin, Kool, Marcel, Kortmann, Rolf-Dieter, Glasow, Annegret, Patties, Ina

Source: International Journal of Molecular Sciences; Apr2022, Vol. 23 Issue 7, p3815-N.PAG, 28p

Subject Terms: COMBINED modality therapy, ABACAVIR, DECITABINE, GENE expression, MICE

Lineage restriction of the RARα gene expression in myeloid differentiation

Authors: Zhu, Jun, Heyworth, Clare M., Glasow, Annegret, Huang, Qiu-Hua, Petrie, Kevin, Lanotte, Michel, Benoit, Gérard, Gallagher, Robert, Waxman, Samuel, Enver, Tariq, Zelent, Arthur

Source: In Blood 15 October 2001 98(8):2563-2567

Dose and Dose Rate-Dependent Effects of Low-Dose Irradiation on Inflammatory Parameters in ApoE-Deficient and Wild Type Mice.

Authors: Glasow, Annegret¹ (AUTHOR) ina.patties@medizin.uni-leipzig.de, Patties, Ina¹ (AUTHOR), Priest, Nicholas D.^2,3 (AUTHOR) mitchelronliz@gmail.com, Mitchel, Ronald E. J.³ (AUTHOR), Hildebrandt, Guido⁴ (AUTHOR) guido.hildebrandt@uni-rostock.de, Manda, Katrin⁴ (AUTHOR) katrin.manda@uni-rostock.de

Source: Cells (2073-4409). Nov2021, Vol. 10 Issue 11, p3251. 1p.

Subject Terms: *LABORATORY mice, *MICE, *SPLEEN, *CYTOKINES, *ENDOTHELIAL cells, *MONOCYTES

D,L-Methadone does not improve radio- and chemotherapy in glioblastoma in vitro.

Authors: Oppermann, Henry, Matusova, Martina, Glasow, Annegret, Dietterle, Johannes, Baran-Schmidt, Rainer, Neumann, Karsten, Meixensberger, Jürgen, Gaunitz, Frank

Source: Cancer Chemotherapy & Pharmacology; Jun2019, Vol. 83 Issue 6, p1017-1024, 8p

Subject Terms: CENTRAL nervous system tumors, CELL survival, CELL culture, CANCER chemotherapy

Geographic Terms: GERMANY

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DNA methylation-independent loss of RARA gene expression in acute myeloid leukemia

Authors: Glasow, Annegret, Barrett, Angela, Petrie, Kevin, Gupta, Rajeev, Boix-Chornet, Manuel, Zhou, Da-Cheng, Grimwade, David, Gallagher, Robert, von Lindern, Marieke, Waxman, Samuel, Enver, Tariq, Hildebrandt, Guido, Zelent, Arthur

Source: In Blood 15 February 2008 111(4):2374-2377