PPARG protein expression in advanced urothelial carcinoma and selection for response to FX-909, a first-in-class PPARG-targeting agent.

Authors: Gjini, Evisa, Motley, William, Joshi, Adarsh, Kakrecha, Bijal, Mertz, Jennifer, Williamson, Kaylyn, Kirov, Stefan, Bowden, Michaela

Source: Journal of Clinical Oncology; 2/20/2025 Supplement 5, Vol. 43, p856-856, 242p

Spatial signatures identify immune escape via PD-1 as a defining feature of T-cell/histiocyte-rich large B-cell lymphoma

Authors: Griffin, Gabriel K. ^*, Weirather, Jason L. ^*, Roemer, Margaretha G.M. ^*, Lipschitz, Mikel, Kelley, Alyssa, Chen, Pei-Hsuan, Gusenleitner, Daniel, Jeter, Erin, Pak, Christine, Gjini, Evisa, Chapuy, Bjoern, Rosenthal, Michael H., Xu, Jie, Chen, Benjamin J., Sohani, Aliyah R., Lovitch, Scott B., Abramson, Jeremy S., Ishizuka, Jeffrey J., Kim, Austin I., Jacobson, Caron A., LaCasce, Ann S., Fletcher, Christopher D., Neuberg, Donna, Freeman, Gordon J., Hodi, F. Stephen, Wright, Kyle, Ligon, Azra H., Jacobsen, Eric D., Armand, Philippe, Shipp, Margaret A., Rodig, Scott J. ^*

Source: In Blood 11 March 2021 137(10):1353-1364

Mass cytometry of Hodgkin lymphoma reveals a CD4+ regulatory T-cell–rich and exhausted T-effector microenvironment

Authors: Cader, Fathima Zumla, Schackmann, Ron C.J., Hu, Xihao ^*, Wienand, Kirsty ^*, Redd, Robert ^*, Chapuy, Bjoern, Ouyang, Jing, Paul, Nicole, Gjini, Evisa, Lipschitz, Mikel, Armand, Philippe, Wu, David, Fromm, Jonathan R., Neuberg, Donna, Liu, X. Shirley, Rodig, Scott J., Shipp, Margaret A.

Source: In Blood 23 August 2018 132(8):825-836

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

Authors: Keskin, Derin, Anandappa, Annabelle, Sun, Jing, Tirosh, Itay, Mathewson, Nathan, Li, Shuqiang, Oliveira, Giacomo, Giobbie-Hurder, Anita, Felt, Kristen, Gjini, Evisa, Shukla, Sachet, Hu, Zhuting, Li, Letitia, Le, Phuong, Allesøe, Rosa, Richman, Alyssa, Kowalczyk, Monika, Abdelrahman, Sara, Geduldig, Jack, Charbonneau, Sarah, Pelton, Kristine, Iorgulescu, J., Elagina, Liudmila, Zhang, Wandi, Olive, Oriol, McCluskey, Christine, Olsen, Lars, Stevens, Jonathan, Lane, William, Salazar, Andres, Daley, Heather, Wen, Patrick, Chiocca, E., Harden, Maegan, Lennon, Niall, Gabriel, Stacey, Getz, Gad, Lander, Eric, Regev, Aviv, Ritz, Jerome, Neuberg, Donna, Rodig, Scott, Ligon, Keith, Suvà, Mario, Wucherpfennig, Kai, Hacohen, Nir, Fritsch, Edward, Livak, Kenneth, Ott, Patrick, Wu, Catherine, Reardon, David

Source: Nature. 565(7738):234-239

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103845853.0x000001&indx=1&recIds=ETOCvdc_100103845853.0x000001

Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade

Authors: Miller, Brian, Sen, Debattama, Al Abosy, Rose, Bi, Kevin, Virkud, Yamini, LaFleur, Martin, Yates, Kathleen, Lako, Ana, Felt, Kristen, Naik, Girish, Manos, Michael, Gjini, Evisa, Kuchroo, Juhi, Ishizuka, Jeffrey, Collier, Jenna, Griffin, Gabriel, Maleri, Seth, Comstock, Dawn, Weiss, Sarah, Brown, Flavian, Panda, Arpit, Zimmer, Margaret, Manguso, Robert, Hodi, F., Rodig, Scott, Sharpe, Arlene, Haining, W.

Source: Nature immunology. 20(3):326-336

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190837748.0x000001&indx=1&recIds=ETOCvdc_100190837748.0x000001

Anti‐PD‐1 Immunotherapy‐Induced Flare of a Known Underlying Relapsing Vasculitis Mimicking Recurrent Cancer

Authors: Nabel, Christopher S., Severgnini, Mariano, Hung, Yin P., Cunningham‐Bussel, Amy, Gjini, Evisa, Kleinsteuber, Katja, Seymour, Lake J., Holland, Martha K., Cunningham, Rachel, Felt, Kristin D., Vivero, Marina, Rodig, Scott J., Massarotti, Elena M., Rahma, Osama E., Harshman, Lauren C.

Source: Oncologist. 24(8):1013-1021

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100086658818.0x000001&indx=1&recIds=ETOCvdc_100086658818.0x000001

Topological analysis reveals a PD-L1-associated microenvironmental niche for Reed-Sternberg cells in Hodgkin lymphoma

Authors: Carey, Christopher D. ^*, Gusenleitner, Daniel ^*, Lipschitz, Mikel, Roemer, Margaretha G.M., Stack, Edward C., Gjini, Evisa, Hu, Xihao, Redd, Robert, Freeman, Gordon J., Neuberg, Donna, Hodi, F. Stephen, Liu, Xiaole Shirley, Shipp, Margaret A., Rodig, Scott J.

Source: In Blood 30 November 2017 130(22):2420-2430

Evaluating the PD-1 Axis and Immune Effector Cell Infiltration in Oropharyngeal Squamous Cell Carcinoma

Authors: Schoenfeld, Jonathan D., Gjini, Evisa, Rodig, Scott J., Tishler, Roy B., Rawal, Bhupendra, Catalano, Paul J., Uppaluri, Ravindra, Haddad, Robert I., Hanna, Glenn J., Chau, Nicole G., Rabinowits, Guilherme, Lorch, Jochen, Jo, Vickie Y., Krane, Jeffrey F., Goguen, Laura A., Annino, Donald J., Abdelrahman, Sara, Lipschitz, Mikel, Margalit, Danielle N.

Source: International journal of radiation oncology, biology, physics. 102(1):137-145

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131080094.0x000001&indx=1&recIds=ETOCvdc_100131080094.0x000001

Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses

Authors: Cañadas, Israel, Thummalapalli, Rohit, Kim, Jong, Kitajima, Shunsuke, Jenkins, Russell, Christensen, Camilla, Campisi, Marco, Kuang, Yanan, Zhang, Yanxi, Gjini, Evisa, Zhang, Gao, Tian, Tian, Sen, Debattama, Miao, Diana, Imamura, Yu, Thai, Tran, Piel, Brandon, Terai, Hideki, Aref, Amir, Hagan, Timothy, Koyama, Shohei, Watanabe, Masayuki, Baba, Hideo, Adeni, Anika, Lydon, Christine, Tamayo, Pablo, Wei, Zhi, Herlyn, Meenhard, Barbie, Thanh, Uppaluri, Ravindra, Sholl, Lynnette, Sicinska, Ewa, Sands, Jacob, Rodig, Scott, Wong, Kwok, Paweletz, Cloud, Watanabe, Hideo, Barbie, David

Source: Nature medicine. 24(8):1143-1150

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A phase 1, first-in-human, dose-escalation and expansion study of FX-909 in patients with advanced solid malignancies, including advanced urothelial carcinoma.

Authors: Iyer, Gopa, Gao, Xin, Rasco, Drew W., Milowsky, Matthew I., Garmezy, Benjamin, Rodriguez Rivera, Ildefonso I, Tepper, Jennifer, Moles, Melissa Ann, Gjini, Evisa, Bowden, Michaela, Meyers, Michael L., Bellmunt, Joaquim, Galsky, Matt D.

Source: Journal of Clinical Oncology; 2024 Supplement 4, Vol. 42, pTPS709-TPS709, 193p

Regression of multifocoal in transit melanoma metastases after palliative resection of dominant masses and 2 years after treatment with ipilimumab

Authors: Moreira, Raphael, Hamieh, Lana, Gjini, Evisa, Lako, Ana, Krajewski, Katherine, Yoon, Charles, Ott, Patrick

Source: Journal for immunotherapy of cancer. 5(1):1-4

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163634881.0x000001&indx=1&recIds=ETOCvdc_100163634881.0x000001

A phase I trial of panobinostat (LBH589) in patients with metastatic melanoma

Authors: Ibrahim, Nageatte, Buchbinder, Elizabeth I., Granter, Scott R., Rodig, Scott J., Giobbie‐Hurder, Anita, Becerra, Carla, Tsiaras, Argyro, Gjini, Evisa, Fisher, David E., Hodi, F. Stephen

Source: Cancer medicine. 5(11):3041-3050

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103348918.0x000001&indx=1&recIds=ETOCvdc_100103348918.0x000001

p63 Mediates an Apoptotic Response to Pharmacological and Disease-Related ER Stress in the Developing Epidermis

Authors: Pyati, Ujwal J., Gjini, Evisa, Carbonneau, Seth, Lee, Jeong-Soo, Guo, Feng, Jette, Cicely A., Kelsell, David P., Look, A. Thomas

Source: In Developmental Cell 13 September 2011 21(3):492-505

cpsf1 is required for definitive HSC survival in zebrafish

Authors: Bolli, Niccolò, Payne, Elspeth M., Rhodes, Jennifer, Gjini, Evisa, Johnston, Adam B., Guo, Feng, Lee, Jeong-Soo, Stewart, Rodney A., Kanki, John P., Chen, Aye T., Zhou, Yi, Zon, Leonard I., Look, A. Thomas

Source: In Blood 14 April 2011 117(15):3996-4007

Role of synectin in lymphatic development in zebrafish and frogs

Authors: Hermans, Karlien ^*, Claes, Filip ^*, Vandevelde, Wouter, Zheng, Wei, Geudens, Ilse, Orsenigo, Fabrizio, De Smet, Frederik, Gjini, Evisa, Anthonis, Kristof, Ren, Bin, Kerjaschki, Dontcho, Autiero, Monica, Ny, Annelii, Simons, Michael, Dewerchin, Mieke, Schulte-Merker, Stefan, Dejana, Elisabetta, Alitalo, Kari, Carmeliet, Peter ^*

Source: In Blood 28 October 2010 116(17):3356-3366

Bevacizumab improves tumor infiltration of mature dendritic cells and effector T-cells in triple-negative breast cancer patients.

Authors: Boucher, Yves, Kumar, Ashwin S., Posada, Jessica M., Gjini, Evisa, Pfaff, Kathleen, Lipschitz, Mikel, Lako, Ana, Duda, Dan G., Rodig, Scott J., Hodi, F. Stephen, Jain, Rakesh K.

Source: NPJ Precision Oncology; 6/29/2021, Vol. 5 Issue 1, p1-6, 6p

Subject Terms: BEVACIZUMAB, DENDRITIC cells, T cells, TRIPLE-negative breast cancer, IMMUNE checkpoint inhibitors

Author Correction: Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade

Authors: Miller, Brian, Sen, Debattama, Al Abosy, Rose, Bi, Kevin, Virkud, Yamini, LaFleur, Martin, Yates, Kathleen, Lako, Ana, Felt, Kristen, Naik, Girish, Manos, Michael, Gjini, Evisa, Kuchroo, Juhi, Ishizuka, Jeffrey, Collier, Jenna, Griffin, Gabriel, Maleri, Seth, Comstock, Dawn, Weiss, Sarah, Brown, Flavian, Panda, Arpit, Zimmer, Margaret, Manguso, Robert, Hodi, F., Rodig, Scott, Sharpe, Arlene, Haining, W.

Source: Nature immunology. 20(11):1556-1556

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190862062.0x000001&indx=1&recIds=ETOCvdc_100190862062.0x000001

FiTAc-seq: fixed-tissue ChIP-seq for H3K27ac profiling and super-enhancer analysis of FFPE tissues.

Authors: Font-Tello, Alba, Kesten, Nikolas, Xie, Yingtian, Taing, Len, Varešlija, Damir, Young, Leonie S., Hamid, Anis A., Van Allen, Eliezer M., Sweeney, Christopher J., Gjini, Evisa, Lako, Ana, Hodi, F. Steven, Bellmunt, Joaquim, Brown, Myles, Cejas, Paloma, Long, Henry W.

Source: Nature Protocols; Aug2020, Vol. 15 Issue 8, p2503-2518, 16p

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