Formulation of Polymeric Micelles to Increase the Solubility and Photostability of Caffeic Acid

Authors: Elisabetta Mazzotta, Martina Chieffallo, Rita Muzzalupo, Miriana Spingola, Paolino Caputo, Martina Romeo, Giuseppina Ioele

Source: Molecules, Vol 29, Iss 14, p 3329 (2024)

Subject Terms: caffeic acid, P123, polymeric micelles, antioxidant activity, photodegradation studies, release studies, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/29/14/3329; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/b801048d0d924aa09d19dbe2d86eda5d

Interaction of letrozole and its degradation products with aromatase: chemometric assessment of kinetics and structure-based binding validation

Authors: Michele De Luca, Maria Antonietta Occhiuzzi, Bruno Rizzuti, Giuseppina Ioele, Gaetano Ragno, Antonio Garofalo, Fedora Grande

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1600-1609 (2022)

Subject Terms: Breast cancer, drug stability, multivariate curve resolution, spectrophotometry, molecular docking, enzyme inhibition, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

Access URL: https://doaj.org/article/63a9b80e702a4829a800e614720c6723

Multivariate Approaches in Quantitative Structure–Property Relationships Study for the Photostability Assessment of 1,4-Dihydropyridine Derivatives

Authors: Martina Chieffallo, Michele De Luca, Fedora Grande, Maria Antonietta Occhiuzzi, Miyase Gözde Gündüz, Antonio Garofalo, Giuseppina Ioele

Source: Pharmaceutics, Vol 16, Iss 2, p 206 (2024)

Subject Terms: photodegradation study, QSPR study, multivariate curve resolution, ordinary least squares, molecular descriptors, ICH rules, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/16/2/206; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/118e6946001645338054141639f4229d

Multivariate Curve Resolution Methodology Applied to the ATR-FTIR Data for Adulteration Assessment of Virgin Coconut Oil

Authors: Michele De Luca, Giuseppina Ioele, Fedora Grande, Maria Antonietta Occhiuzzi, Martina Chieffallo, Antonio Garofalo, Gaetano Ragno

Source: Molecules, Vol 28, Iss 12, p 4661 (2023)

Subject Terms: virgin coconut oil, food analysis, infrared spectroscopy, multivariate analysis, calibration model, variable selection, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/12/4661; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/38bb3b2888ea4c98bd9e19bc2ac92585

Wine Lees as Source of Antioxidant Molecules: Green Extraction Procedure and Biological Activity

Authors: Michele De Luca, Donatella Restuccia, Umile Gianfranco Spizzirri, Pasquale Crupi, Giuseppina Ioele, Beatrice Gorelli, Maria Lisa Clodoveo, Simona Saponara, Francesca Aiello

Source: Antioxidants, Vol 12, Iss 3, p 622 (2023)

Subject Terms: wine lees, green extraction procedure, principal component analysis, partial least square regression, antioxidant properties, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/12/3/622; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/ff0056aee311471da52fea595a048868

Carbazoles: Role and Functions in Fighting Diabetes

Authors: Fedora Grande, Giuseppina Ioele, Anna Caruso, Maria Antonietta Occhiuzzi, Hussein El-Kashef, Carmela Saturnino, Maria Stefania Sinicropi

Source: Applied Sciences, Vol 13, Iss 1, p 349 (2022)

Subject Terms: carbazoles, alkaloids, diabetes mellitus, antihyperglycemic agents, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3417/13/1/349; https://doaj.org/toc/2076-3417

Access URL: https://doaj.org/article/589f222d6ce3425f8ba96066c4cfe747

Anticancer Drugs: Recent Strategies to Improve Stability Profile, Pharmacokinetic and Pharmacodynamic Properties

Authors: Giuseppina Ioele, Martina Chieffallo, Maria Antonietta Occhiuzzi, Michele De Luca, Antonio Garofalo, Gaetano Ragno, Fedora Grande

Source: Molecules, Vol 27, Iss 17, p 5436 (2022)

Subject Terms: cancer therapy, drug stability, prodrugs, vesicular systems, nanoparticles, trastuzumab, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/17/5436; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/554a35f1821041bdbce2fd319785557c

Photosensitive drugs: a review on their photoprotection by liposomes and cyclodextrins

Authors: Giuseppina Ioele, Michele De Luca, Antonio Garofalo, Gaetano Ragno

Source: Drug Delivery, Vol 24, Iss 2, Pp 33-44 (2017)

Subject Terms: Photolabile drugs, stability tests, phototoxicity, photoprotection, supramolecular matrices, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1071-7544; https://doaj.org/toc/1521-0464

Access URL: https://doaj.org/article/8521ce2d75b74317945eeedf74b880b2

Photodegradation of Anti-Inflammatory Drugs: Stability Tests and Lipid Nanocarriers for Their Photoprotection

Authors: Giuseppina Ioele, Fedora Grande, Michele De Luca, Maria Antonietta Occhiuzzi, Antonio Garofalo, Gaetano Ragno

Source: Molecules, Vol 26, Iss 19, p 5989 (2021)

Subject Terms: photodegradation, ICH Quality Guidelines, liposomes, niosomes, solid lipid nanoparticles, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/19/5989; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/b4bb487ce23a425192289d479818f07e

Polyphenols from Citrus Tacle® Extract Endowed with HMGCR Inhibitory Activity: An Antihypercholesterolemia Natural Remedy

Authors: Fedora Grande, Maria Antonietta Occhiuzzi, Maria Rosaria Perri, Giuseppina Ioele, Bruno Rizzuti, Giancarlo Statti, Antonio Garofalo

Source: Molecules, Vol 26, Iss 18, p 5718 (2021)

Subject Terms: flavanones, anti-enzymatic assays, molecular docking, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/18/5718; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/580c2a413c124249b79437e778255d25

Toward Multitasking Pharmacological COX-Targeting Agents: Non-Steroidal Anti-Inflammatory Prodrugs with Antiproliferative Effects

Authors: Fedora Grande, Francesca Giordano, Maria Antonietta Occhiuzzi, Carmine Rocca, Giuseppina Ioele, Michele De Luca, Gaetano Ragno, Maria Luisa Panno, Bruno Rizzuti, Antonio Garofalo

Source: Molecules, Vol 26, Iss 13, p 3940 (2021)

Subject Terms: COX-1, COX-2, nabumetone, molecular docking, anti-enzymatic assays, cell toxicity, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/13/3940; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/34b8da0bc0274fbca49c6ebe3ae8bf98

Use of Pluronic Surfactants in Gel Formulations of Photosensitive 1,4-Dihydropyridine Derivatives: A Potential Approach in the Treatment of Neuropathic Pain

Authors: Giuseppina Ioele, Rita Muzzalupo, Miyase Gözde Gündüz, Michele De Luca, Elisabetta Mazzotta, Fedora Grande, Maria Antonietta Occhiuzzi, Antonio Garofalo, Gaetano Ragno

Source: Pharmaceutics, Vol 13, Iss 4, p 527 (2021)

Subject Terms: T-type calcium channel blockers, multivariate curve resolution, drug photostability, Pluronic® surfactants, α-tocopherol, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/13/4/527; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/e23e36880ca542f4ad464a0fcd514eab

Efficacy of Red Glass in Protecting 1,4-Dihydropyridine Antihypertensive Drugs in Liquid Formulations

Authors: Michele De Luca, Giuseppina Ioele, Fedora Grande, Gaetano Ragno

Source: Applied Sciences, Vol 11, Iss 8, p 3442 (2021)

Subject Terms: dihydropyridine drugs, photoprotection, stressing test, glass containers, multivariate curve resolution, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3417/11/8/3442; https://doaj.org/toc/2076-3417

Access URL: https://doaj.org/article/51e9bd951c2a4faead57a66400534231

Gel Formulation of Nabumetone and a Newly Synthesized Analog: Microemulsion as a Photoprotective Topical Delivery System

Authors: Fedora Grande, Gaetano Ragno, Rita Muzzalupo, Maria Antonietta Occhiuzzi, Elisabetta Mazzotta, Michele De Luca, Antonio Garofalo, Giuseppina Ioele

Source: Pharmaceutics, Vol 12, Iss 5, p 423 (2020)

Subject Terms: anti-inflammatory drugs, nabumetone, photostability, microemulsion-in-gel, multivariate curve resolution, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/12/5/423; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/216b8176bae341899ac7ee191017d1e5

Optimization of wavelength range and data interval in chemometric analysis of complex pharmaceutical mixtures

Authors: Michele De Luca, Giuseppina Ioele, Claudia Spatari, Gaetano Ragno

Source: Journal of Pharmaceutical Analysis, Vol 6, Iss 1, Pp 64-69 (2016)

Subject Terms: Chemometrics, Spectrophotometry, Principal component analysis, Partial least squares, Multivariate curve resolution, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2095177915300095; https://doaj.org/toc/2095-1779

Access URL: https://doaj.org/article/da75a71626ed4db096301d1590299e30

Chemometric classification of citrus juices of Moroccan cultivars by infrared spectroscopy

Authors: Aziz HIRRI, Michele DE LUCA, Giuseppina IOELE, Abdessamad BALOUKI, El Mahfoud El BASSBASI, Fouzia KZAIBER, Abdelkhalek OUSSAMA, Gaetano RAGNO

Source: Czech Journal of Food Sciences, Vol 33, Iss 2, Pp 137-142 (2015)

Subject Terms: fourier transform infrared, multivariate analysis, cultivar classification, principal component analysis, partial least squares-discriminant analysis, Agriculture

File Description: electronic resource

Relation: https://cjfs.agriculturejournals.cz/artkey/cjf-201502-0006_chemometric-classification-of-citrus-juices-of-moroccan-cultivars-by-infrared-spectroscopy.php; https://doaj.org/toc/1212-1800; https://doaj.org/toc/1805-9317

Access URL: https://doaj.org/article/b2f0a5d423754dc293f6456a1cbbd987

Reverse Transcriptase Inhibitors Nanosystems Designed for Drug Stability and Controlled Delivery

Authors: Fedora Grande, Giuseppina Ioele, Maria Antonietta Occhiuzzi, Michele De Luca, Elisabetta Mazzotta, Gaetano Ragno, Antonio Garofalo, Rita Muzzalupo

Source: Pharmaceutics, Vol 11, Iss 5, p 197 (2019)

Subject Terms: HIV, antiretrovirals, nanoformulations, drug degradation, drug protection, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/11/5/197; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/621cfc1de16c4726b208c4f0a2420ef9

1,4-Dihydropyridine Antihypertensive Drugs: Recent Advances in Photostabilization Strategies

Authors: Michele De Luca, Giuseppina Ioele, Gaetano Ragno

Source: Pharmaceutics, Vol 11, Iss 2, p 85 (2019)

Subject Terms: 1,4-dihydropyridines, photostabilization, liposomes, cyclodextrins, light-absorbing excipients, opaque containers, nanosystems, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/11/2/85; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/d81b27a7dc9044cfb00f5fdbb776bd19

CCR5/CXCR4 Dual Antagonism for the Improvement of HIV Infection Therapy

Authors: Fedora Grande, Maria Antonietta Occhiuzzi, Bruno Rizzuti, Giuseppina Ioele, Michele De Luca, Paola Tucci, Valentina Svicher, Stefano Aquaro, Antonio Garofalo

Source: Molecules, Vol 24, Iss 3, p 550 (2019)

Subject Terms: chemokine receptors, dual drugs, HIV entry, AIDS, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/24/3/550; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/55ac533f106c4d0085029167df8c2d20

A New Generation of Dihydropyridine Calcium Channel Blockers: Photostabilization of Liquid Formulations Using Nonionic Surfactants

Authors: Giuseppina Ioele, Miyase Gözde Gündüz, Claudia Spatari, Michele De Luca, Fedora Grande, Gaetano Ragno

Source: Pharmaceutics, Vol 11, Iss 1, p 28 (2019)

Subject Terms: 1,4-dihydropyridines, L- and T-type calcium channel blockers, photodegradation test, light-stable formulation, micellar solution, PET containers, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: http://www.mdpi.com/1999-4923/11/1/28; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/de8050abfe9641bcbddfe9a428ebfdd4