Development and application of an LC-MS/MS method for the combined quantification of oxysterols and bile acids

Authors: Martin Roumain, Giulio G. Muccioli

Source: Journal of Lipid Research, Vol 66, Iss 1, Pp 100697- (2025)

Subject Terms: lipidomics, lipids, sterols, cholesterol metabolism, cytochrome P450, liquid chromatography mass spectrometry, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227524002025; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/e939c9bf39a04689a72a72ffc8c82c97

A gut microbiota-independent mechanism shapes the bile acid pool in mice with MASH

Authors: Justine Gillard, Martin Roumain, Corinne Picalausa, Morgane M. Thibaut, Laure-Alix Clerbaux, Anne Tailleux, Bart Staels, Giulio G. Muccioli, Laure B. Bindels, Isabelle A. Leclercq

Source: JHEP Reports, Vol 6, Iss 11, Pp 101148- (2024)

Subject Terms: Bile acids, Enterohepatic cycle, 7α-Dehydroxylation, 7α-Rehydroxylation, Gut microbiota, Clostridium scindens, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924001526; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/8243d95a065e44218b65e8767a320ff1

A nanoparticle platform for combined mucosal healing and immunomodulation in inflammatory bowel disease treatment

Authors: Valentina Marotti, Yining Xu, Cécilia Bohns Michalowski, Wunan Zhang, Inês Domingues, Hafsa Ameraoui, Tom G. Moreels, Pieter Baatsen, Matthias Van Hul, Giulio G. Muccioli, Patrice D. Cani, Mireille Alhouayek, Alessio Malfanti, Ana Beloqui

Source: Bioactive Materials, Vol 32, Iss , Pp 206-221 (2024)

Subject Terms: Nanocarrier, GLP-2, Teduglutide, KPV, Inflammatory bowel disease, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X23002979; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/3f85c90a219f44b0bab7992bff6c1026

Influence of a pro-inflammatory stimulus on the miRNA and lipid content of human dental stem cell-derived extracellular vesicles and their impact on microglial activation

Authors: Viridiane Gratpain, Axelle Loriot, Pauline Bottemanne, Ludovic d’Auria, Romano Terrasi, Valéry L. Payen, Vincent van Pesch, Giulio G. Muccioli, Anne des Rieux

Source: Heliyon, Vol 10, Iss 5, Pp e27025- (2024)

Subject Terms: Extracellular vesicles, Mesenchymal stem cells, Size-exclusion chromatography, Neuroinflammation, miRNA, Lipidomics, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024030561; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/6e81f85a5fa34f1895470616e09b52da

Inulin increases the beneficial effects of rhubarb supplementation on high-fat high-sugar diet-induced metabolic disorders in mice: impact on energy expenditure, brown adipose tissue activity, and microbiota

Authors: Marion Régnier, Matthias Van Hul, Martin Roumain, Adrien Paquot, Alice de Wouters d’Oplinter, Francesco Suriano, Amandine Everard, Nathalie M. Delzenne, Giulio G. Muccioli, Patrice D. Cani

Source: Gut Microbes, Vol 15, Iss 1 (2023)

Subject Terms: obesity, high-fat diet high-sucrose, prebiotics, brown adipose tissue, energy expenditure, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/c3fc990484e34b9495e7534dc9d110a5

Dysosmobacter welbionis effects on glucose, lipid, and energy metabolism are associated with specific bioactive lipids

Authors: Emilie Moens de Hase, Camille Petitfils, Mireille Alhouayek, Clara Depommier, Pauline Le Faouder, Nathalie M. Delzenne, Matthias Van Hul, Giulio G. Muccioli, Nicolas Cenac, Patrice D. Cani

Source: Journal of Lipid Research, Vol 64, Iss 10, Pp 100437- (2023)

Subject Terms: Dysosmobacter welbionis J115T, obesity, bioactive lipids, brown adipose tissue, colon, dietary fat, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227523001104; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/74d84574bf134e0899e57c7aade431be

Chitin-glucan supplementation improved postprandial metabolism and altered gut microbiota in subjects at cardiometabolic risk in a randomized trial

Authors: Harimalala Ranaivo, Zhengxiao Zhang, Maud Alligier, Laurie Van Den Berghe, Monique Sothier, Stéphanie Lambert-Porcheron, Nathalie Feugier, Charlotte Cuerq, Christelle Machon, Audrey M. Neyrinck, Benjamin Seethaler, Julie Rodriguez, Martin Roumain, Giulio G. Muccioli, Véronique Maquet, Martine Laville, Stephan C. Bischoff, Jens Walter, Nathalie M. Delzenne, Julie-Anne Nazare

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/76a9eaab21dd442e8d14d2312c879fd7

'To brain or not to brain': evaluating the possible direct effects of the satiety factor oleoylethanolamide in the central nervous system

Authors: Adele Romano, Marzia Friuli, Barbara Eramo, Cristina Anna Gallelli, Justyna Barbara Koczwara, Elnaz Karimian Azari, Adrien Paquot, Myrtha Arnold, Wolfgang Langhans, Giulio G. Muccioli, Thomas Alexander Lutz, Silvana Gaetani

Source: Frontiers in Endocrinology, Vol 14 (2023)

Subject Terms: brain distribution, hormones, gut-brain axis, N-acylethanolamines, N-oleoylethanolamine, eating behavior, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2023.1158287/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/a4a71c269d254baab06ed62af0e9408d

EBI2 is a negative modulator of brown adipose tissue energy expenditure in mice and human brown adipocytes

Authors: Francesca Copperi, Inna Schleis, Martin Roumain, Giulio G. Muccioli, Stefano Casola, Martin Klingenspor, Alexander Pfeifer, Thorsten Gnad

Source: Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/38c7ef6bb2f0416ea97ba86de74291a0

Atorvastatin population pharmacokinetics in a real‐life setting: Influence of genetic polymorphisms and association with clinical response

Authors: Gabriel Stillemans, Adrien Paquot, Giulio G. Muccioli, Emilia Hoste, Nadtha Panin, Anders Åsberg, Jean‐Luc Balligand, Vincent Haufroid, Laure Elens

Source: Clinical and Translational Science, Vol 15, Iss 3, Pp 667-679 (2022)

Subject Terms: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

Access URL: https://doaj.org/article/3e74fcb644e746a7b4cefd7b2d602aaf

Effect of a methanolic extract of Salvadora oleoides Decne. on LPS-activated J774 macrophages, its in vitro and in vivo toxicity study and dereplication of its chemical constituents

Authors: Hafiz Abdul Khaliq, Sergio Ortiz, Mireille Alhouayek, Tanguy Neyts, Giulio G. Muccioli, Joëlle Quetin-Leclercq

Source: Toxicology Reports, Vol 9, Iss , Pp 1742-1753 (2022)

Subject Terms: OECD, Oral toxicity, Inflammation, GNPS, Flavonoids, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214750022001871; https://doaj.org/toc/2214-7500

Access URL: https://doaj.org/article/bdd18e2463314baaabd230f45e72015b

Gut barrier and microbiota changes with glycine and branched‐chain amino acid supplementation in chronic haemodialysis patients

Authors: Laurence Genton, Menno Pruijm, Daniel Teta, Isabelle Bassi, Patrice D. Cani, Nadia Gaïa, François R. Herrmann, Nicola Marangon, Julie Mareschal, Giulio G. Muccioli, Catherine Stoermann, Francesco Suriano, Arlene Wurzner‐Ghajarzadeh, Vladimir Lazarevic, Jacques Schrenzel

Source: Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 6, Pp 1527-1539 (2021)

Subject Terms: Gut microbiota, Glycine, Branched‐chain amino acid malnutrition, Endocannabinoids, Appetite, Diseases of the musculoskeletal system, RC925-935, Human anatomy, QM1-695

File Description: electronic resource

Relation: https://doaj.org/toc/2190-5991; https://doaj.org/toc/2190-6009

Access URL: https://doaj.org/article/d7d2300fefa94c4c836ee888f2ae612e

Canagliflozin protects against sepsis capillary leak syndrome by activating endothelial α1AMPK

Authors: Marine Angé, Julien De Poortere, Audrey Ginion, Sylvain Battault, Mélanie Dechamps, Giulio G. Muccioli, Martin Roumain, Johann Morelle, Sébastien Druart, Thomas Mathivet, Luc Bertrand, Diego Castanares-Zapatero, Sandrine Horman, Christophe Beauloye

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/dc9c7a02d37340ff943334e7a5f7da61

Novel insights into the genetically obese (ob/ob) and diabetic (db/db) mice: two sides of the same coin

Authors: Francesco Suriano, Sara Vieira-Silva, Gwen Falony, Martin Roumain, Adrien Paquot, Rudy Pelicaen, Marion Régnier, Nathalie M. Delzenne, Jeroen Raes, Giulio G. Muccioli, Matthias Van Hul, Patrice D. Cani

Source: Microbiome, Vol 9, Iss 1, Pp 1-20 (2021)

Subject Terms: Leptin-deficiency, Leptin-receptor deficiency, ob/ob, db/db, Lipopolysaccharides, Bile acids, Microbial ecology, QR100-130

File Description: electronic resource

Relation: https://doaj.org/toc/2049-2618

Access URL: https://doaj.org/article/d890b4d856184f9f98fdd2efbb56f9bd

Diesel exhaust particles alter the profile and function of the gut microbiota upon subchronic oral administration in mice

Authors: Sybille van den Brule, Margaux Rappe, Jérôme Ambroise, Caroline Bouzin, Chantal Dessy, Adrien Paquot, Giulio G. Muccioli, Dominique Lison

Source: Particle and Fibre Toxicology, Vol 18, Iss 1, Pp 1-15 (2021)

Subject Terms: Air pollution, Particles, Cardiovascular diseases, Metabolic diseases, Short-chain fatty acids, Atherosclerosis, Toxicology. Poisons, RA1190-1270, Industrial hygiene. Industrial welfare, HD7260-7780.8

File Description: electronic resource

Relation: https://doaj.org/toc/1743-8977

Access URL: https://doaj.org/article/8f3dc1acf7f2480293d97c0ea4830df0

Inflammation‐induced cholestasis in cancer cachexia

Authors: Morgane M. Thibaut, Martina Sboarina, Martin Roumain, Sarah A. Pötgens, Audrey M. Neyrinck, Florence Destrée, Justine Gillard, Isabelle A. Leclercq, Guillaume Dachy, Jean‐Baptiste Demoulin, Anne Tailleux, Sophie Lestavel, Marialetizia Rastelli, Amandine Everard, Patrice D. Cani, Paolo E. Porporato, Audrey Loumaye, Jean‐Paul Thissen, Giulio G. Muccioli, Nathalie M. Delzenne, Laure B. Bindels

Source: Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 1, Pp 70-90 (2021)

Subject Terms: Liver, Hepatobiliary transport system, Bile acids, IL‐6, Cholestyramine, Diseases of the musculoskeletal system, RC925-935, Human anatomy, QM1-695

File Description: electronic resource

Relation: https://doaj.org/toc/2190-5991; https://doaj.org/toc/2190-6009

Access URL: https://doaj.org/article/72205912f187498f8a32fd94de95284b

Contribution of Membrane Vesicle to Reprogramming of Bacterial Membrane Fluidity in Pseudomonas aeruginosa

Authors: Negar Mozaheb, Patrick Van Der Smissen, Tomas Opsomer, Eric Mignolet, Romano Terrasi, Adrien Paquot, Yvan Larondelle, Wim Dehaen, Giulio G. Muccioli, Marie-Paule Mingeot-Leclercq

Source: mSphere, Vol 7, Iss 3 (2022)

Subject Terms: P. aeruginosa, bacterial membrane, membrane vesicles, fluidity, biofilm, biofilms, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5042

Access URL: https://doaj.org/article/3695abb022434d4fbc52801825e0001f

On the Reaction of 2-Alkanoylnaphthohydroquinones with Hydroxylamine: Access to Cytotoxic 2-(Hydroxyamino)-1,4-naphthoquinone and Their 3-(Hydroxyimino)alkyl Analogous

Authors: Jaime A. Valderrama, Andrea Pérez-Herrera, Giulio G. Muccioli, Edmundo A. Venegas-Casanova, Rafael Jara-Aguilar, Pedro Buc Calderon, Julio Benites

Source: Journal of Chemistry, Vol 2022 (2022)

Subject Terms: Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2090-9071

Access URL: https://doaj.org/article/896959ef273b400cb700e199f407e506

Germ-free mice exhibit profound gut microbiota-dependent alterations of intestinal endocannabinoidome signaling

Authors: Claudia Manca, Besma Boubertakh, Nadine Leblanc, Thomas Deschênes, Sebastien Lacroix, Cyril Martin, Alain Houde, Alain Veilleux, Nicolas Flamand, Giulio G. Muccioli, Frédéric Raymond, Patrice D. Cani, Vincenzo Di Marzo, Cristoforo Silvestri

Source: Journal of Lipid Research, Vol 61, Iss 1, Pp 70-85 (2020)

Subject Terms: endocannabinoids, gut microbiome, germ-free phenotype, intestine, fecal microbiota transplant, gene expression, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520300171; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/ef199b9fe7fb4b669cf51e3d20b3c87b

Impaired Cytoskeletal and Membrane Biophysical Properties of Acanthocytes in Hypobetalipoproteinemia – A Case Study

Authors: Anne-Sophie Cloos, Laura G. M. Daenen, Mauriane Maja, Amaury Stommen, Juliette Vanderroost, Patrick Van Der Smissen, Minke Rab, Jan Westerink, Eric Mignolet, Yvan Larondelle, Romano Terrasi, Giulio G. Muccioli, Andra C. Dumitru, David Alsteens, Richard van Wijk, Donatienne Tyteca

Source: Frontiers in Physiology, Vol 12 (2021)

Subject Terms: acanthocytosis, lipidomics, lipid domains, membrane biophysical properties, reactive oxygen species, ceramide, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2021.638027/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/06470655076b47c5982e9ae8553009a9