'It depends': Configuring AI to Improve Clinical Usefulness Across Contexts

Authors: Zając, Hubert D., Ribeiro, Jorge M. N., Ingala, Silvia, Gentile, Simona, Wanjohi, Ruth, Gitau, Samuel N., Carlsen, Jonathan F., Nielsen, Michael B., Andersen, Tariq O.

Subject Terms: Computer Science - Human-Computer Interaction, Computer Science - Artificial Intelligence

Access URL: http://arxiv.org/abs/2407.11978

Evaluating Biparametric Versus Multiparametric Magnetic Resonance Imaging for Diagnosing Clinically Significant Prostate Cancer: An International, Paired, Noninferiority, Confirmatory Observer Study

Authors: Twilt, Jasper J. ^ac, Saha, Anindo ^ac, Bosma, Joeran S. ^ac, van Ginneken, Bram ^ac, Noordman, Constant R. ^ac, Slootweg, Ivan ^ac, Roest, Christian ^ad, Fransen, Stefan J. ^ad, Sunoqrot, Mohammed R.S. ^{ae, af}, Bathen, Tone F. ^{ae, af}, Rouw, Dennis ^ag, Geerdink, Jeroen ^ah, van Run, Chris ^ac, Groeneveld, Miriam ^ac, Meakin, James ^ac, Immerzeel, Jos J.F.M. ^ai, Yakar, Derya ^{ad, aj}, Elschot, Mattijs ^{ae, af}, Veltman, Jeroen ^ah, Fütterer, Jurgen J. ^ac, de Rooij, Maarten ^ac, Huisman, Henkjan ^{ac, ae}, Bjartell, Anders ^ak, Padhani, Anwar R. ^al, Bonekamp, David ^am, Villeirs, Geert ^an, Salomon, Georg ^ao, Giannarini, Gianluca ^ap, Kalpathy-Cramer, Jayashree ^aq, Barentsz, Jelle ^ai, Maier-Hein, Klaus H. ^{am, ar}, Rusu, Mirabela ^as, Obuchowski, Nancy A. ^at, Rouviere, Olivier ^au, van den Bergh, Roderick ^av, Panebianco, Valeria ^aw, Kasivisvanathan, Veeru ^{ax, ay}, Malakoti-Fard, Afsoun ^az, Mačiūnien, Agnė ^ba, Kawashima, Akira ^bb, Gaivão, Ana M. ^bc, Moreira, Ana S.L. ^bd, Ponsiglione, Andrea ^be, Rappaport, Annelies ^bf, Stanzione, Arnaldo ^be, Ciuvasovas, Arturas ^ba, Turkbey, Baris ^bg, Keyzer, Bart De ^bf, Pedersen, Bodil G. ^bh, Eijlers, Bram ^av, Chen, Christine ^bi, Riccardo, Ciabattoni ^bj, Alis, Deniz ^bk, Courrech Staal, Ewout F.W. ^bl, Thimansson, Erik ^bm, Jäderling, Fredrik ^bn, Langkilde, Fredrik ^bo, Aringhieri, Giacomo ^bp, Brembilla, Giorgio ^bq, Son, Hannah ^br, van der Lelij, Hans ^bl, Raat, Henricus P.J. ^bs, Pikūnienė, Ingrida ^bt, Macova, Iva ^bu, Schoots, Ivo ^{av, aj}, Caglic, Iztok ^bv, Zawaideh, Jeries P. ^bw, Wallström, Jonas ^bo, Bittencourt, Leonardo K. ^bx, Khurram, Misbah ^by, Choi, Moon Hyung ^bz, Takahashi, Naoki ^ca, Tan, Nelly ^bb, Franco, Paolo N. ^cb, Gutierrez, Patricia A. ^cc, Hanus, Petr ^bu, Puech, Philippe ^cc, Rau, Philipp R. ^cd, de Visschere, Pieter ^an, Guillaume, Ramette ^ce, Cuocolo, Renato ^cf, Falcão, Ricardo O. ^cg, van Stiphout, Rogier S.A. ^bs, Girometti, Rossano ^{ch, ci}, Briediene, Ruta ^cj, Grigienė, Rūta ^cj, Gitau, Samuel ^ck, Withey, Samuel ^cl, Ghai, Sangeet ^cm, Penzkofer, Tobias ^cn, Barrett, Tristan ^bv, Tammisetti, Varaha Sai ^co, Løgager, Vibeke B. ^az, Černý, Vladimír ^bu, Venderink, Wulphert ^ac, Law, Yan Mee ^cp, Lee, Young Joon ^cq, Rouvière, Olivier ^{o, p}

Source: In European Urology February 2025 87(2):240-250

Artificial intelligence and radiologists in prostate cancer detection on MRI (PI-CAI): an international, paired, non-inferiority, confirmatory study

Authors: Saha, Anindo, Bosma, Joeran S., Twilt, Jasper J., van Ginneken, Bram, Noordman, Constant R., Slootweg, Ivan, Roest, Christian, Fransen, Stefan J., Sunoqrot, Mohammed R.S., Bathen, Tone F., Rouw, Dennis, Immerzeel, Jos, Geerdink, Jeroen, van Run, Chris, Groeneveld, Miriam, Meakin, James, Karagöz, Ahmet, Bône, Alexandre, Routier, Alexandre, Marcoux, Arnaud, Abi-Nader, Clément, Li, Cynthia Xinran, Feng, Dagan, Alis, Deniz, Karaarslan, Ercan, Ahn, Euijoon, Nicolas, François, Sonn, Geoffrey A., Bhattacharya, Indrani, Kim, Jinman, Shi, Jun, Jahanandish, Hassan, An, Hong, Kan, Hongyu, Oksuz, Ilkay, Qiao, Liang, Rohé, Marc-Michel, Yergin, Mert, Khadra, Mohamed, Şeker, Mustafa E., Kartal, Mustafa S., Debs, Noëlie, Fan, Richard E., Saunders, Sara, Soerensen, Simon J.C., Moroianu, Stefania, Vesal, Sulaiman, Yuan, Yuan, Malakoti-Fard, Afsoun, Mačiūnien, Agnė, Kawashima, Akira, de Sousa Machadov, Ana M.M. de M.G., Moreira, Ana Sofia L., Ponsiglione, Andrea, Rappaport, Annelies, Stanzione, Arnaldo, Ciuvasovas, Arturas, Turkbey, Baris, de Keyzer, Bart, Pedersen, Bodil G., Eijlers, Bram, Chen, Christine, Riccardo, Ciabattoni, Courrech Staal, Ewout F.W., Jäderling, Fredrik, Langkilde, Fredrik, Aringhieri, Giacomo, Brembilla, Giorgio, Son, Hannah, Vanderlelij, Hans, Raat, Henricus P.J., Pikūnienė, Ingrida, Macova, Iva, Schoots, Ivo, Caglic, Iztok, Zawaideh, Jeries P., Wallström, Jonas, Bittencourt, Leonardo K., Khurram, Misbah, Choi, Moon H., Takahashi, Naoki, Tan, Nelly, Franco, Paolo N., Gutierrez, Patricia A., Thimansson, Per Erik, Hanus, Pieter, Puech, Philippe, Rau, Philipp R., de Visschere, Pieter, Guillaume, Ramette, Cuocolo, Renato, Falcão, Ricardo O., van Stiphout, Rogier S.A., Girometti, Rossano, Briediene, Ruta, Grigienė, Rūta, Gitau, Samuel, Withey, Samuel, Ghai, Sangeet, Penzkofer, Tobias, Barrett, Tristan, Tammisetti, Varaha S., Løgager, Vibeke B., Černý, Vladimír, Venderink, Wulphert, Law, Yan M., Lee, Young J., Bjartell, Anders, Padhani, Anwar R., Bonekamp, David, Villeirs, Geert, Salomon, Georg, Giannarini, Gianluca, Kalpathy-Cramer, Jayashree, Barentsz, Jelle, Maier-Hein, Klaus H., Rusu, Mirabela, Obuchowski, Nancy A., Rouvière, Olivier, van den Bergh, Roderick, Panebianco, Valeria, Kasivisvanathan, Veeru, Yakar, Derya, Elschot, Mattijs, Veltman, Jeroen, Fütterer, Jurgen J., de Rooij, Maarten, Huisman, Henkjan, Bosma, Joeran S ^*, Twilt, Jasper J ^*, Padhani, Anwar R, Maier-Hein, Klaus H, Obuchowski, Nancy A, Fütterer, Jurgen J

Source: In The Lancet Oncology July 2024 25(7):879-887

Thyroid Cartilage Metastases from Prostate Cancer on 18F PSMA PET CT: A Case Series.

Authors: Loyal, Poonamjeet¹ (AUTHOR) poonamjeet.loyal@aku.edu, Gitau, Samuel² (AUTHOR), Makhdomi, Khalid³ (AUTHOR)

Source: World Journal of Nuclear Medicine. Sep2024, Vol. 23 Issue 3, p199-201. 3p.

Subject Terms: *TRACHEAL cartilage, *POSITRON emission tomography, *CANCER patients, *PROSTATE cancer patients, *THYROID cancer, *PROSTATE cancer

Supraclavicular nodal metastasis at primary staging of prostate cancer using ¹⁸F-PSMA-1007 PET/CT.

Authors: Gitau, Samuel Nguku¹ samuel.gitau@aku.edu, Shah, Jasmit² jasmit.shah@aku.edu, Olwit, William¹ william.olwit@aku.edu, Saeed, Samnakay³ saeed.samnakay@aku.edu, Mansour, Manel Haj⁴ haj.manel@aku.edu, Makhdomi, Khalid¹ khalid.makhomi@aku.edu

Source: EJNMMI Reports. 3/17/2025, Vol. 9 Issue 1, p1-13. 13p.

Subject Terms: *PROSTATE cancer, *CANCER diagnosis, *COMPUTED tomography, *MEDICAL sciences, *DATA analysis

Seroprevalence of anti-SARS-CoV-2 IgM and IgG and COVID-19 vaccine uptake in healthy volunteers in Nairobi, Kenya: a cross-sectional study.

Authors: Otindo, Agnes Muhonja¹, Ndombi, Eric M.^1,2, emakuto@gmail.com, Theuri, Martin¹, Muturi, Margaret¹, Thamaini, Peris³, Ogutu, James², Onsongo, Lister⁴, Madete, June K.⁵, Ofula, Victor⁶, Gitau, Samuel⁷, Mwangi, Gladys⁷, Okemo, Paul⁸

Source: Frontiers in Virology; 2024, p1-10, 10p

Association Between CA 15-3 and ¹⁸F-FDG PET/CT Findings in Recurrent Breast Cancer Patients at a Tertiary Referral Hospital in Kenya.

Authors: Mwania, Margaret M., Gitau, Samuel Nguku, Shah, Jasmit, Makhdomi, Khalid

Source: Journal of Nuclear Medicine; Oct2024, Vol. 65 Issue 10, p1521-1525, 5p

Clinical characteristics, anti-SARS-CoV-2 IgG titers, and inflammatory markers in individuals with post-COVID-19 condition in Kenya: a cross-sectional study.

Authors: Theuri, Martin, Ndombi, Eric M., Thamaini, Peris, Ogutu, James Opiyo, Onsongo, Lister, Madete, June K., Ofula, Victor, Gitau, Samuel, Mwangi, Gladys, Okemo, Paul

Source: PeerJ; Jul2024, p1-17, 17p

Subject Terms: CLINICAL chemistry, ENZYME-linked immunosorbent assay, C-reactive protein, COVID-19 pandemic, VOLUNTEER recruitment

HIV-Associated Cardiovascular Disease Pathogenesis: An Emerging Understanding Through Imaging and Immunology.

Authors: Hudson, Jonathan A., Ferrand, Rashida A., Gitau, Samuel N., Mureithi, Marianne Wanjiru, Maffia, Pasquale, Alam, Shirjel R., Shah, Anoop S. V.

Source: Circulation Research; 5/24/2024, Vol. 134 Issue 11, p1546-1565, 20p

Kiosk 7R-TA-04 - Cardiac Inflammation Based on Multi-modality Imaging and Its Relation to Viraemia and Systemic Inflammation in Viral Myocarditis

Authors: Mouy, Florence, Horn, Kevin, Vinayak, Sudhir, Makhdomi, Khalid, Ombati, Kevin, El-Medany, Ahmed, Scott, Rachel, Obino, Mariah, Nganga, Edward, Chung, Michael, Shah, Anoop, Bowen, Stephen, Gitau, Samuel, Alam, Shirjel

Source: In Journal of Cardiovascular Magnetic Resonance Spring 2024 26 Supplement 1

Aspirin Reduces Cardiac Interstitial Fibrosis by Inhibiting Erk1/2-Serpine2 and P-Akt Signalling Pathways

Authors: Li, Xuelian, Wang, GuoYuan, QiLi, MuGe, Liang, HaiHai, Li, TianShi, E, XiaoQiang, Feng, Ying, Zhang, Ying, Liu, Xiao, Qian, Ming, Xu, BoZhi, Shen, ZhiHang, Gitau, Samuel Chege, Zhao, DanDan, Shan, HongLi

Source: Cellular physiology and biochemistry. 45(5):1955-1965

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085677835.0x000001&indx=1&recIds=ETOCvdc_100085677835.0x000001

Lower limb lymphoscintigraphy patterns among patients with lower limb lymphedema: a pictorial essay

Authors: Nganga, Edward C., Gitau, Samuel, Makhdomi, Khalid

Source: Clinical and translational imaging. 6(2):135-143

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131008022.0x000001&indx=1&recIds=ETOCvdc_100131008022.0x000001

Optimal method for metabolic tumour volume assessment of cervical cancers with inter-observer agreement on [18F]-fluoro-deoxy-glucose positron emission tomography with computed tomography.

Authors: Arshad, Mubarik A.¹ (AUTHOR) mubarik@doctors.org.uk, Gitau, Samuel¹ (AUTHOR), Tam, Henry¹ (AUTHOR), Park, Won-Ho E.² (AUTHOR), Patel, Neva H.¹ (AUTHOR), Rockall, Andrea^1,3 (AUTHOR), Aboagye, Eric O.³ (AUTHOR), Bharwani, Nishat^1,3 (AUTHOR), Barwick, Tara D.^1,3 (AUTHOR)

Source: European Journal of Nuclear Medicine & Molecular Imaging. Jun2021, Vol. 48 Issue 6, p2009-2023. 15p. 2 Color Photographs, 1 Diagram, 6 Charts.

Subject Terms: *COMPUTED tomography, *CERVICAL cancer, *POSITRON emission tomography computed tomography, *TUMORS

Bone scintigraphy imaging of cardiac amyloidosis

Authors: Kuria, Issa, Gitau, Samuel, Makhdomi, Khalid

Source: WORLD JOURNAL OF NUCLEAR MEDICINE. 18(3):314-316

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100088762239.0x000001&indx=1&recIds=ETOCvdc_100088762239.0x000001

Cisapride protects against cardiac hypertrophy via inhibiting the up-regulation of calcineurin and NFATc-3

Authors: Zhou, Xin, Zhang, Qi, Zhao, Tianyang, Bai, Xiaopeng, Yuan, Wei, Wu, Yanping, Liu, Di, Li, Shuang, Ju, Jiaming, Chege Gitau, Samuel, Chu, Wenfeng, Xu, Chaoqian, Lu, Yanjie

Source: In European Journal of Pharmacology 15 July 2014 735:202-210

The Antifibrotic Effects and Mechanisms of MicroRNA-26a Action in Idiopathic Pulmonary Fibrosis

Authors: Liang, Haihai, Xu, Chaoqian, Pan, Zhenwei, Zhang, Ying, Xu, Zhidan, Chen, Yingzhun, Li, Tianyu, Li, Xuelian, Liu, Ying, Huangfu, Longtao, Lu, Ying, Zhang, Zhihua, Yang, Baofeng, Gitau, Samuel, Lu, Yanjie, Shan, Hongli, Du, Zhimin

Source: In Molecular Therapy June 2014 22(6):1122-1133

Spectrum of imaging findings in AIDS-related diffuse large B cell lymphoma.

Authors: Nganga, Edward Chege¹ (AUTHOR) edward.nganga@aku.edu, Gitau, Samuel¹ (AUTHOR)

Source: Insights into Imaging. 5/19/2020, Vol. 11 Issue 1, p1-8. 8p.

Subject Terms: *DIFFUSE large B-cell lymphomas, *B cells, *KAPOSI'S sarcoma, *OPPORTUNISTIC infections, *HIV-positive persons, *VIRAL load

A Rare Case of Biliary Atresia with Biliary Ascites on a (Hepatobiliary Iminodiacetic Acid) HIDA Scan.

Authors: Loyal, Poonamjeet Kaur, Makhdomi, Khalid, Gitau, Samuel

Source: World Journal of Nuclear Medicine; Jun2024, Vol. 23 Issue 2, p123-125, 3p

Subject Terms: ASCITES, BILIARY atresia, PEDIATRIC surgery, ACIDS

The Female Brain Health and Endocrine Research in Africa Study (FemBER‐AFRICA): Identifying endocrinological, lifestyle, psychosocial and socio‐cultural targets for Alzheimer's disease prevention in women of African ancestry.

Authors: Udeh‐Momoh, Chinedu, Maina, Rachel W, Bosire, Edna N, Khakali, Linda N, Gregory, Sarah, Blackmon, Karen, Thesen, Thomas, Kafetsouli, Dimitra, Gitau, Samuel, Njogu, Anne Nyambura, Smith, Cynthia, Mbugua, Sylvia, Waa, Sheila, Shah, Jasmit N, Muchungi, Kendi, Hill‐Jarrett, Tanisha G, Tsoy, Elena, Merali, Zul, Yokoyama, Jennifer S., Solomon, Alina

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Dec2024 Supplement 7, Vol. 20 Issue S7, p1-2, 2p

Endometriosis management in a low/middle income country – Integration of a multidisciplinary medical team and patient social support group

Authors: Muteshi, Charles, Mwaka, Gilbert, Duncan, Andrew, Gitau, Samuel, Kathiresan, Prabu, Bwika, Jumaa, Yousef, Ahmed, Wandera, Elsie

Source: Journal of Endometriosis and Pelvic Pain Disorders; 20250101, Issue: Preprints