Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition

Authors: Crespo-Garcia, Sergio, Tsuruda, Pamela R., Dejda, Agnieszka, Ryan, Rathi D., Fournier, Frederik, Chaney, Shawnta Y., Pilon, Frederique, Dogan, Taner, Cagnone, Gael, Patel, Priyanka, Buscarlet, Manuel, Dasgupta, Sonali, Girouard, Gabrielle, Rao, Surabhi R., Wilson, Ariel M., O’Brien, Robert, Juneau, Rachel, Guber, Vera, Dubrac, Alexandre, Beausejour, Christian, Armstrong, Scott, Mallette, Frederick A., Yohn, Christopher B., Joyal, Jean-Sebastien, Marquess, Dan, Beltran, Pedro J., Sapieha, Przemyslaw

Source: In Cell Metabolism 6 April 2021 33(4):818-832

Obesity triggers tumoral senescence and renders poorly immunogenic malignancies amenable to senolysis.

Authors: Fournier, Frédérik, Diaz-Marin, Roberto, Pilon, Frédérique, Neault, Mathieu, Juneau, Rachel, Girouard, Gabrielle, Wilson, Ariel M., Larrivée, Bruno, Mallette, Frédérick A., Crespo-Garcia, Sergio, Sapieha, Przemyslaw

Source: Proceedings of the National Academy of Sciences of the United States of America; 1/3/2023, Vol. 120 Issue 1, p1-10, 32p

Subject Terms: TUMOR growth, BODY mass index, OBESITY, DISEASE risk factors

New stimulation ligand of the adenovirus 2 protease.

Authors: Diouri, Mounir, Girouard, Gabrielle S., Allen, Cynthia M.

Source: Virology; October 15 1996, Vol. 224, p510-516, 7p

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