GDF15 Circulating Levels Are Associated with Metabolic-Associated Liver Injury and Atherosclerotic Cardiovascular Disease.

Authors: Girona, Josefa^1,2,3,4 (AUTHOR), Guardiola, Montse^1,2,3,4 (AUTHOR), Barroso, Emma^3,4,5,6,7 (AUTHOR), García-Altares, María^4,8 (AUTHOR), Ibarretxe, Daiana^1,2,3,4,5 (AUTHOR), Plana, Núria^1,2,3,4,6 (AUTHOR), Ribalta, Josep^1,2,3,4,7 (AUTHOR), Amigó, Núria^3,4,8,9,10 (AUTHOR), Correig, Xavier^4,8,9 (AUTHOR), Vázquez-Carrera, Manuel^4,5,6,7,10 (AUTHOR), Masana, Lluís^1,2,3,4 (AUTHOR), Rodríguez-Calvo, Ricardo^1,2,3,4 (AUTHOR) ricardo.rodriguez@ciberdem.org

Source: International Journal of Molecular Sciences. Mar2025, Vol. 26 Issue 5, p2039. 13p.

Subject Terms: *GROWTH differentiation factors, *NUCLEAR magnetic resonance, *LIVER injuries, *CARDIOVASCULAR diseases, *LIPOPROTEINS

ApoC-III proteoforms are associated with better lipid, inflammatory, and glucose profiles independent of total apoC-III.

Authors: Rehues, Pere^1,2,3 (AUTHOR), Girona, Josefa^1,2,3 (AUTHOR), Guardiola, Montse^1,2,3 (AUTHOR) montse.guardiola@urv.cat, Ozcariz, Enrique^4,5 (AUTHOR), Amigó, Núria^2,3,5,6,7 (AUTHOR), Rosales, Roser^1,2,3 (AUTHOR), Esteban, Yaiza^1,2,3 (AUTHOR), Banús, Helena¹ (AUTHOR), Gavaldà-Alsina, Gemma^1,2 (AUTHOR), González-Lleó, Ana^8,9 (AUTHOR), Rojo-Martínez, Gemma^3,10 (AUTHOR), Ribalta, Josep^1,2,3 (AUTHOR)

Source: Cardiovascular Diabetology. 12/4/2024, Vol. 23 Issue 1, p1-15. 15p.

Subject Terms: *PROTON magnetic resonance, *TYPE 2 diabetes, *APOLIPOPROTEIN C, *INSULIN resistance, *NUCLEAR magnetic resonance

PCSK9 Antibodies Treatment Specifically Enhances the Macrophage-specific Reverse Cholesterol Transport Pathway in Heterozygous Familial Hypercholesterolemia

Authors: Borràs, Carla, Canyelles, Marina, Girona, Josefa, Ibarretxe, Daiana, Santos, David, Revilla, Giovanna, Llorente-Cortes, Vicenta, Rotllan, Noemí, Kovanen, Petri T., Jauhiainen, Matti, Lee-Rueckert, Miriam, Masana, Luis, Arrieta, Francisco, Martínez-Botas, Javier, Gómez-Coronado, Diego, Ribalta, Josep, Tondo, Mireia, Blanco-Vaca, Francisco, Escolà-Gil, Joan Carles

Source: In JACC: Basic to Translational Science October 2024 9(10):1195-1210

The GDF15 3′ UTR Polymorphism rs1054564 Is Associated with Diabetes and Subclinical Atherosclerosis.

Authors: Guardiola, Montse^1,2,3,4 (AUTHOR), Girona, Josefa^1,2,3,4 (AUTHOR), Barroso, Emma^4,5,6,7 (AUTHOR), García-Altares, María^4,8 (AUTHOR), Ibarretxe, Daiana^1,2,3,4 (AUTHOR), Plana, Núria^1,2,3,4 (AUTHOR), Ribalta, Josep^1,2,3,4 (AUTHOR), Correig, Xavier^4,8 (AUTHOR), Vázquez-Carrera, Manuel^4,5,6,7 (AUTHOR), Masana, Lluís^1,2,3,4 (AUTHOR), Rodríguez-Calvo, Ricardo^1,2,3,4 (AUTHOR) ricardo.rodriguez@ciberdem.org

Source: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 22, p11985. 10p.

Subject Terms: *GROWTH differentiation factors, *ATHEROSCLEROTIC plaque, *GENETIC variation, *SINGLE nucleotide polymorphisms, *METABOLIC disorders

Association between Nordic and Mediterranean diets with lipoprotein phenotype assessed by 1HNMR in children with familial hypercholesterolemia

Authors: Rodríguez-Borjabad, Cèlia, Narveud, Ingunn, Christensen, Jacob Juel, Ibarretxe, Daiana, Andreychuk, Natalia, Girona, Josefa, Torvik, Kristin, Folkedal, Guro, Bogsrud, Martin P., Retterstøl, Kjetil, Plana, Núria, Masana, Luis, Holven, Kirsten B.

Source: In Atherosclerosis May 2023 373:38-45

Lipidomics Reveals Myocardial Lipid Composition in a Murine Model of Insulin Resistance Induced by a High-Fat Diet.

Authors: Girona, Josefa^1,2 (AUTHOR), Soler, Oria^1,2 (AUTHOR), Samino, Sara^2,3 (AUTHOR), Junza, Alexandra^2,3 (AUTHOR), Martínez-Micaelo, Neus^1,2 (AUTHOR), García-Altares, María^2,3 (AUTHOR), Ràfols, Pere^2,3 (AUTHOR), Esteban, Yaiza^1,2 (AUTHOR), Yanes, Oscar^2,3 (AUTHOR), Correig, Xavier^2,3 (AUTHOR), Masana, Lluís^1,2 (AUTHOR), Rodríguez-Calvo, Ricardo^1,2 (AUTHOR) ricardo.rodriguez@ciberdem.org

Source: International Journal of Molecular Sciences. Mar2024, Vol. 25 Issue 5, p2702. 15p.

Subject Terms: *HIGH-fat diet, *INSULIN resistance, *LIPIDOMICS, *LIQUID chromatography-mass spectrometry, *METABOLOMIC fingerprinting, *LIPIDS

Serum glycoproteins A and B assessed by 1H-NMR in familial hypercholesterolemia

Authors: Malo, Ana-Irene, Girona, Josefa, Ibarretxe, Daiana, Rodríguez-Borjabad, Cèlia, Amigó, Núria, Plana, Núria, Masana, Lluís

Source: In Atherosclerosis August 2021 330:1-7

Dietary intake and lipid levels in Norwegian and Spanish children with familial hypercholesterolemia

Authors: Rodríguez-Borjabad, Cèlia, Narveud, Ingunn, Christensen, Jacob Juel, Ulven, Stine Marie, Malo, Ana Irene, Ibarretxe, Daiana, Girona, Josefa, Torvik, Kristin, Bogsrud, Martin Prøven, Retterstøl, Kjetil, Plana, Núria, Masana, Luis, Holven, Kristen Bjørklund

Source: In Nutrition, Metabolism and Cardiovascular Diseases 9 April 2021 31(4):1299-1307

Statistical mediation of the relationships between chronological age and lipoproteins by nonessential amino acids in healthy men

Authors: Mallol, Roger, Vallvé, Joan Carles, Solà, Rosa, Girona, Josefa, Bergmann, Sven, Correig, Xavier, Rock, Edmond, Winklhofer-Roob, Brigitte M, Rehues, Pere, Guardiola, Montse, Masana, Lluís, Ribalta, Josep

Source: In Computational and Structural Biotechnology Journal 2021 19:6169-6178

Triglyceride-independent associations between circulating levels of apolipoprotein C-III and biomarkers of inflammation.

Authors: Llop, Dídac, Rehues, Pere, Paredes, Silvia, Guardiola, Montse, Girona, Josefa, Rosales, Roser, Esteban, Yaiza, Masana, Lluís, Ibarretxe, Daiana, Vallvé, Joan-Carles, Ribalta, Josep

Source: Cardiovascular Diabetology; 1/8/2025, Vol. 24 Issue 1, p1-10, 10p

Subject Terms: C-reactive protein, APOLIPOPROTEIN C, TYPE 2 diabetes, GLYCOPROTEINS, METABOLIC disorders

Efficacy of therapeutic lifestyle changes on lipid profiles assessed by NMR in children with familial and non-familial hypercholesterolemia

Alternate Title: Eficacia de los cambios terapéuticos en el estilo de vida en el perfil lipídico evaluado por RMN en niños con hipercolesterolemia familiar y no familiar (Spanish; Castilian)

Authors: Fèlix, Aguado, Elisabet, Amigó, Patricia, Andrés, Mercedes, Barrio, Ángel, Bilbao José, Montserrat, Bosch, Luis, Cabedo Jose, Josefa, Calvo, Carmen, Campillo, Alejandra, Caselles, Enma, Castejón, Gemma, Castillejo, Maria, Castro, Rosa, Cliville, Enrique, De Gotardo, Rebeca, De La Hoz, Vanesa, Domènech, Dolores, Domínguez, Maria, Escolà, Marta, Fernández, Joan, García, Raquel, Girona, Sílvia, Gispi, Jara, Guàrdia, Eugenio, Guijarro, MªAntonia, Gutierrez, Dolores, Iglesias, Marta, Jiménez, Verónica, Luque, Pilar, Machado, Jordi, Maixé, Marta, Mallafré, Ramona, Martin, Milagros, Jiménez, Raquel, Monne, Raquel, Morales, Susana, Morillo, Àngels, Naranjo, Cristina, Pérez, MªTeresa, Pérez, Montserrat, Planelles, Cecilia, Querol, MªJosé, Rabadà, Ayelen, Remedi, Carmen, Riquelme, Neus, Rodríguez, Laura, Rosell, Miquel, Roset Laura Salsas Jaume, Maria, Salvadó, Olga, Salvador, Alicia, Santos, Sandra, Segura, Gloria, Subirana, Pilar, Tarrades, Montserrat, Vendrell, Mireia, Vilella, Eduardo, Zabala, Rodríguez-Borjabad, Cèlia, Malo, Ana Irene, Ibarretxe, Daiana, Girona, Josefa, Heras, Mercedes, Ferré, Raimon, Feliu, Albert, Salvadó, María, Varela, Anna, Amigó, Núria, Masana, Luis, Plana, Núria

Source: In Clínica e Investigación en arteriosclerosis (English edition) March-April 2020 32(2):49-58

Plasma glucose, triglycerides, VLDL, leptin and resistin levels as potential biomarkers for myocardial fat in mice

Alternate Title: Niveles plasmáticos de glucosa, triglicéridos, VLDL, leptina y resistina como potenciales biomarcadores de la grasa miocárdica en ratones (Spanish; Castilian)

Authors: Rodríguez-Calvo, Ricardo ^*, Samino, Sara, Guaita-Esteruelas, Sandra, Martínez-Micaelo, Neus, Heras, Mercedes, Girona, Josefa, Yanes, Oscar, Correig, Xavier, Masana, Lluis ^*

Source: In Clínica e Investigación en arteriosclerosis (English edition) January-February 2020 32(1):8-14

Niveles plasmáticos de glucosa, triglicéridos, VLDL, leptina y resistina como potenciales biomarcadores de la grasa miocárdica en ratones

Alternate Title: Plasma glucose, triglycerides, VLDL, leptin and resistin levels as potential biomarkers for myocardial fat in mice (English)

Authors: Rodríguez-Calvo, Ricardo, Samino, Sara, Guaita-Esteruelas, Sandra, Martínez-Micaelo, Neus, Heras, Mercedes, Girona, Josefa, Yanes, Oscar, Correig, Xavier, Masana, Lluis

Source: In Clinica e Investigacion en Arteriosclerosis January-February 2020 32(1):8-14

Fatty acid binding protein 4 (FABP4) as a potential biomarker reflecting myocardial lipid storage in type 2 diabetes

Authors: Rodríguez-Calvo, Ricardo, Girona, Josefa, Rodríguez, Marina, Samino, Sara, Barroso, Emma, de Gonzalo-Calvo, David, Guaita-Esteruelas, Sandra, Heras, Mercedes, van der Meer, Rutger W., Lamb, Hildo J., Yanes, Oscar, Correig, Xavier, Llorente-Cortés, Vicenta, Vázquez-Carrera, Manuel, Masana, Lluis

Source: In Metabolism July 2019 96:12-21

Enhanced Association of Novel Cardiovascular Biomarkers Fetuin-A and Catestatin with Serological and Inflammatory Markers in Rheumatoid Arthritis Patients.

Authors: Pàmies, Anna, Llop, Dídac, Ibarretxe, Daiana, Rosales, Roser, Girona, Josefa, Masana, Lluís, Vallvé, Joan-Carles, Paredes, Silvia

Source: International Journal of Molecular Sciences; Sep2024, Vol. 25 Issue 18, p9910, 15p

Subject Terms: CAROTID intima-media thickness, CAROTID artery ultrasonography, BLOOD sedimentation, RHEUMATOID factor, ATHEROSCLEROTIC plaque

PCSK9 Inhibitors Have Apolipoprotein C-III-Related Anti-Inflammatory Activity, Assessed by 1H-NMR Glycoprotein Profile in Subjects at High or very High Cardiovascular Risk.

Authors: Rehues, Pere^1,2,3 (AUTHOR), Girona, Josefa^1,2,3 (AUTHOR), Guardiola, Montse^1,2,3 (AUTHOR) montse.guardiola@urv.cat, Plana, Núria^2,3,4 (AUTHOR), Scicali, Roberto⁵ (AUTHOR), Piro, Salvatore⁵ (AUTHOR), Muñiz-Grijalvo, Ovidio⁶ (AUTHOR), Díaz-Díaz, José Luis⁷ (AUTHOR), Recasens, Lluís^8,9 (AUTHOR), Pinyol, Marta¹ (AUTHOR), Rosales, Roser^1,2,3 (AUTHOR), Esteban, Yaiza^1,2,3 (AUTHOR), Amigó, Núria^2,3,10 (AUTHOR), Masana, Lluís^1,2,3,4 (AUTHOR), Ibarretxe, Daiana^1,2,3,4 (AUTHOR) montse.guardiola@urv.cat, Ribalta, Josep^1,2,3 (AUTHOR)

Source: International Journal of Molecular Sciences. Feb2023, Vol. 24 Issue 3, p2319. 15p.

Subject Terms: *ANTI-inflammatory agents, *APOLIPOPROTEIN C, *BLOOD lipoproteins, *LDL cholesterol, *CHOLESTERYL ester transfer protein, *CARDIOVASCULAR diseases risk factors, *HDL cholesterol, *APOLIPOPROTEIN E4, *LOW density lipoproteins

FABP4 inhibitor BMS309403 decreases saturated-fatty-acid-induced endoplasmic reticulum stress-associated inflammation in skeletal muscle by reducing p38 MAPK activation

Authors: Bosquet, Alba, Girona, Josefa, Guaita-Esteruelas, Sandra, Heras, Mercedes, Saavedra-García, Paula, Martínez-Micaelo, Neus, Masana, Lluís, Rodríguez-Calvo, Ricardo

Source: In BBA - Molecular and Cell Biology of Lipids June 2018 1863(6):604-613

Clinical and pathophysiological evidence supporting the safety of extremely low LDL levels—The zero-LDL hypothesis

Authors: Masana, Luis, Girona, Josefa, Ibarretxe, Daiana, Rodríguez-Calvo, Ricardo, Rosales, Roser, Vallvé, Joan-Carles, Rodríguez-Borjabad, Cèlia, Guardiola, Montserrat, Rodríguez, Marina, Guaita-Esteruelas, Sandra, Oliva, Iris, Martínez-Micaelo, Neus, Heras, Mercedes, Ferré, Raimon, Ribalta, Josep, Plana, Núria

Source: In Journal of Clinical Lipidology March-April 2018 12(2):292-299

Lipoprotein profile assessed by 2D-1H-NMR and subclinical atherosclerosis in children with familial hypercholesterolaemia

Authors: Fèlix, Aguado, Elisabeth, Amigó, Patricia, Andrés, Mercedes, Barrio, Ángel, Bilbao José, Montserrat, Bosch, Luís, Cabedo José, Josefa, Calvo, Carmen, Campillo, Emma, Castejón, Gemma, Castillejo, María, Castro, Rosa, Cliville, Enrique, De Gotardo, Vanesa, Doménech, Dolores, Domínguez, Marta, Duràn-Ballén, Maria, Escolà, Marta, Fernández, Joan, García, Raquel, Girona, a<%2Fce%3Asup>%22">Antonia, Gutiérrez Ma<%2Fce%3Asup>%22">José, Rabadà M